Scholars@Duke
Joseph Donald Brogan

Joseph Donald Brogan

Assistant Professor of Medicine
Medicine, Hospital Medicine

Selected Publications

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.

Journal Article J Biol Chem · June 8, 2012 The cardiac Na(+) channel Na(V)1.5 current (I(Na)) is critical to cardiac excitability, and altered I(Na) gating has been implicated in genetic and acquired arrhythmias. Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is up-regulated in heart failur ... Full text Link to item Cite