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Joseph Ladowski

House Staff
Surgery

Current Appointments & Affiliations


Recent Publications


Major histocompatibility complex Matchmaker: An in silico based algorithm to analyze cross-species nonhuman primate, pig, and human major histocompatibility complex compatibility at the amino acid level.

Journal Article Am J Transplant · November 4, 2025 Xenotransplantation received US Food and Drug Administration approval for clinical trials in humans, and highly sensitized patients-those with antibodies against major histocompatibility complex (MHC)-are among the groups that stand to benefit. There is no ... Full text Link to item Cite

Xenotransplantation: Promises and Perils.

Journal Article Annu Rev Med · October 8, 2025 Xenotransplantation of genetically modified pig organs has the potential to change the landscape of transplantation and chronic disease management by providing limitless personalized organs on demand. Decades of progress have resulted in recent US Food and ... Full text Link to item Cite

International Xenotransplantation Association (IXA) Position Paper on Kidney Xenotransplantation.

Journal Article Transplantation · August 2025 Porcine kidney xenotransplantation for end-stage renal disease (ESRD) has reached the stage of clinical testing following major advances in donor pig genetic modifications and effective immunosuppressive strategies through decades of rigorous translational ... Full text Cite
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Recent Grants


Development of a Publicly Available MHC Matchmaker Algorithm

ResearchPrincipal Investigator · Awarded by American Society of Histocompatibility and Immunogenetics · 2024 - 2025

Genetic Engineering of the Swine Leukocyte Antigen as a Method to Decrease Human T Cell Reactivity

ResearchPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2023 - 2025

The Effect of a Desensitization Protocol in Highly Sensitized Renal Transplant Recipients on T Follicular Helper Cells

FellowshipPI-Fellow · Awarded by National Institutes of Health · 2023 - 2024

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