Skip to main content

Joseph Patrick Horrigan

Medical Associate Professor in the Department of Psychiatry and Behavioral Sciences
Psychiatry, Child & Family Mental Health & Community Psychiatry
DUMC 2737, Durham, NC 27710
2424 Erwin Road, Suite 501, Durham, NC 27705

Current Appointments & Affiliations


Medical Associate Professor in the Department of Psychiatry and Behavioral Sciences · 2025 - Present Psychiatry, Child & Family Mental Health & Community Psychiatry, Psychiatry & Behavioral Sciences

Recent Publications


An open-label study evaluating the safety and efficacy of AMO-01 for the treatment of seizures in Phelan-McDermid syndrome.

Journal Article HGG Adv · April 10, 2025 Phelan-McDermid syndrome (PMS) is a neurodevelopmental disorder caused by haploinsufficiency of the SHANK3 gene. Approximately 25% of individuals with PMS have epilepsy. Treatment of epilepsy in PMS may require multiple anticonvulsants, and in a minority o ... Full text Link to item Cite

International workshop: what is needed to ensure outcome measures for Rett syndrome are fit-for-purpose for clinical trials? June 7, 2023, Nashville, USA.

Journal Article Trials · December 21, 2024 INTRODUCTION: The clinical, research and advocacy communities for Rett syndrome are striving to achieve clinical trial readiness, including having fit-for-purpose clinical outcome assessments. This study aimed to (1) describe psychometric properties of cli ... Full text Link to item Cite

Ensuring Stakeholder Feedback in the Design and Conduct of Clinical Trials for Rare Diseases: ISCTM Position Paper of the Orphan Disease Working Group.

Journal Article Innov Clin Neurosci · 2024 The 1983 Orphan Drug Act in the United States (US) changed the landscape for development of therapeutics for rare or orphan diseases, which collectively affect approximately 300 million people worldwide, half of whom are children. The act has undoubtedly a ... Link to item Cite
View All Publications

Education, Training & Certifications


University of Rochester, School of Medicine and Dentistry · 1988 M.D.