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Joshua Colin Vessey

Medical Assistant Professor in the Department of Medicine
Medicine, Hospital Medicine
302 Watts Bldg, DRH, Durham, NC 27704
Duke Regional Hospital, 3643 N Roxboro St -302 Watts, Durham, NC 27704

Selected Publications


Physiology of the third heart sound: novel insights from tissue Doppler imaging.

Journal Article J Am Soc Echocardiogr · April 2008 BACKGROUND: The third heart sound (S(3)) is thought to be caused by the abrupt deceleration of left ventricular (LV) inflow during early diastole, increased LV filling pressures, and decreased LV compliance. We sought to determine whether the ratio of earl ... Full text Link to item Cite

Performance of phonoelectrocardiographic left ventricular systolic time intervals and B-type natriuretic peptide levels in the diagnosis of left ventricular dysfunction.

Journal Article Ann Noninvasive Electrocardiol · April 2007 BACKGROUND: Systolic time intervals measured by echocardiography and carotid artery tracings are validated methods of assessing left ventricular function. However, the clinical utility of phonoelectrocardiographic systolic time intervals for predicting hea ... Full text Link to item Cite

Diagnostic characteristics of combining phonocardiographic third heart sound and systolic time intervals for the prediction of left ventricular dysfunction.

Journal Article J Card Fail · February 2007 BACKGROUND: The third heart sound (S3) and systolic time intervals (STIs) are validated clinical indicators of left ventricular (LV) dysfunction. We investigated the test characteristics of a combined score summarizing S3 and STI results for predicting LV ... Full text Link to item Cite

The utility of gestures in patients with chest discomfort.

Journal Article Am J Med · January 2007 PURPOSE: Patient gestures are thought to be useful in determining the etiology of chest discomfort. We sought to determine the utility of certain patient gestures in the diagnosis of ischemic chest discomfort or myocardial infarction. METHODS: We performed ... Full text Link to item Cite

Relationship between accurate auscultation of a clinically useful third heart sound and level of experience.

Journal Article Arch Intern Med · March 27, 2006 BACKGROUND: Poor performance by physicians-in-training and interobserver variability between physicians have diminished clinicians' confidence in the value of the third heart sound (S3). METHODS: To determine whether auscultation of a clinically useful S3 ... Full text Link to item Cite

High-sensitivity C-reactive protein and parameters of left ventricular dysfunction.

Journal Article J Card Fail · February 2006 BACKGROUND: Elevated levels of high-sensitivity C-reactive protein (CRP), an inflammatory marker, have been associated with heart failure. However, it is not known which parameters of left ventricular dysfunction correlate with elevated levels of CRP. METH ... Full text Link to item Cite

Obese patients have lower B-type and atrial natriuretic peptide levels compared with nonobese.

Journal Article Congest Heart Fail · 2006 Obesity is a risk factor for the development of heart failure, but the causal mechanism remains unclear. Impaired production or enhanced clearance of natriuretic peptides, which regulate sodium balance and sympathetic activation, may play an important role ... Full text Link to item Cite

Association between phonocardiographic third and fourth heart sounds and objective measures of left ventricular function.

Journal Article JAMA · May 11, 2005 CONTEXT: The third (S3) and fourth (S4) heart sounds detected by phonocardiography are considered to represent the criterion standards of the gallop sounds, but their test characteristics have not been explored. OBJECTIVE: To determine the diagnostic test ... Full text Link to item Cite