Current Appointments & Affiliations
Assistant Research Professor in the Department of Biomedical Engineering
·
2025 - Present
Biomedical Engineering,
Pratt School of Engineering
Recent Publications
Phage therapy with nebulized cocktail BX004-A for chronic Pseudomonas aeruginosa infections in cystic fibrosis: a randomized first-in-human trial.
Journal Article Nature communications · July 2025 Cystic fibrosis is a monogenetic disease complicated by recurrent bacterial lung infections that require chronic antibiotics. Pseudomonas aeruginosa is an increasingly antibiotic-resistant pathogen associated with cystic fibrosis morbidity and mortality. H ... Full text CiteBacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis.
Journal Article Nature communications · June 2023 Primary sclerosing cholangitis (PSC) is characterized by progressive biliary inflammation and fibrosis. Although gut commensals are associated with PSC, their causative roles and therapeutic strategies remain elusive. Here we detect abundant Klebsiella pne ... Full text CiteTargeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation.
Journal Article Cell · August 2022 Human gut commensals are increasingly suggested to impact non-communicable diseases, such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a daunting unmet challenge. In four geographically distinct IBD cohorts (n = 537), we ide ... Full text CiteEducation, Training & Certifications
Weizmann Institute of Science (Israel) ·
2017
MD./PhD.