Scholars@Duke
Julie Joo Yeon Kim-Chang

Julie Joo Yeon Kim-Chang

Assistant Professor of Pediatrics
Pediatrics, Allergy and Immunology
DUMC Box 2644, Durham, NC 27710
203 Research Drive (MSRB1, Room 127), Durham, NC 27710

Selected Publications

Multi-Modal Profiling Reveals Contrasting Immunomodulatory Effects of Recreational Marijuana Used Alone or with Tobacco in Youth with HIV.

Journal Article Cells · August 16, 2025 The evolving legal landscape has increased marijuana accessibility across the United States, including for medical use to manage clinical symptoms among people with HIV. The effects of marijuana use remain understudied in youth with HIV (YWH), who face lif ... Full text Link to item Cite

Pediatric oral food challenges in the outpatient setting: A single-center experience.

Journal Article J Allergy Clin Immunol Glob · February 2024 BACKGROUND: Oral food challenge (OFC) is the criterion standard for diagnosing food allergy (FA). It is important to have parameters to aid in selecting ideal OFC candidates. OBJECTIVE: We sought to characterize outcomes and predictors of OFCs for common f ... Full text Link to item Cite

Case Report: Profound newborn leukopenia related to a novel RAC2 variant.

Journal Article Front Pediatr · 2024 We report the case of a 1-week-old male born full-term, who had two inconclusive severe combined immunodeficiency (SCID) newborn screens and developed scalp cellulitis and Escherichia coli bacteremia. He did not pass early confirmatory hearing screens. Ini ... Full text Open Access Link to item Cite

Maternal immunity shapes biomarkers of germinal center development in HIV-exposed uninfected infants.

Journal Article Front Immunol · 2024 INTRODUCTION: HIV-exposed uninfected (HEU) infants exhibit elevated pro-inflammatory biomarkers that persist after birth. However, comprehensive assessments of bioprofiles associated with immune regulation and development in pregnant women with HIV (PWH) a ... Full text Link to item Cite

Recent Advances and Controversies in Inborn Errors of Immunity Presenting in the Newborn Period

Chapter · August 1, 2023 Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles! ... Cite

Biomarkers detected in cord blood predict vaccine responses in young infants.

Journal Article Front Immunol · 2023 INTRODUCTION: Factors influencing vaccine immune priming in the first year of life involve both innate and adaptive immunity but there are gaps in understanding how these factors sustain vaccine antibody levels in healthy infants. The hypothesis was that b ... Full text Link to item Cite

Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana.

Journal Article Retrovirology · May 31, 2022 BACKGROUND: Marijuana's putative anti-inflammatory properties may benefit HIV-associated comorbidities. How recreational marijuana use affects gene expression in peripheral blood cells (PBC) among youth with HIV-1 (YWH) is unknown. APPROACH: YWH with defin ... Full text Open Access Link to item Cite

Defining the Clinical, Emotional, Social, and Financial Burden of Congenital Athymia.

Journal Article Adv Ther · August 2021 INTRODUCTION: Characterize the burden of illness in pediatric patients with congen̄ital athymia who were receiving supportive care. METHODS: This cross-sectional study of adult caregivers of patients with congenital athymia used both a quantitative survey a ... Full text Link to item Cite

Trajectories of Depressive Symptoms, Neurocognitive Function, and Viral Suppression With Antiretroviral Therapy Among Youth With HIV Over 36 months.

Journal Article J Acquir Immune Defic Syndr · June 1, 2021 BACKGROUND: Depression and neurocognitive impairment are highly prevalent among persons living with HIV and associated with poorer clinical outcomes; however, longitudinal studies of depression-neurocognition relationships in youth living with HIV (YLWH), ... Full text Link to item Cite

Economic burden of congenital athymia in the United States for patients receiving supportive care during the first 3 years of life.

Journal Article J Med Econ · 2021 AIMS: Congenital athymia is an ultra-rare pediatric condition characterized by the lack of thymus in utero and the naïve T cells critical for infection defense and immune regulation. Patients with congenital athymia receive supportive care to minimize and ... Full text Link to item Cite

Higher soluble CD14 levels are associated with lower visuospatial memory performance in Youth with HIV (YWH).

Journal Article AIDS · September 2, 2019 OBJECTIVE: HIV-associated neurocognitive disorders persist despite early antiretroviral therapy (ART) and optimal viral suppression. We examined the relationship between immunopathogenesis driven by various pathways of immune activation and discrete neuroc ... Full text Link to item Cite

Tenofovir Has Minimal Effect on Biomarkers of Bone Health in Youth with HIV Receiving Initial Antiretroviral Therapy.

Journal Article AIDS Res Hum Retroviruses · August 2019 Both HIV infection and tenofovir disoproxil fumarate (TDF) treatment adversely impact bone metabolism and may lead to osteopenia, which has critical implications for youth with HIV (YWH). This study evaluates changes in the biomarkers of bone metabolism an ... Full text Link to item Cite

A Pilot Study of Omalizumab in Eosinophilic Esophagitis

Journal Article PLOS ONE · March 19, 2015 Full text Cite

Migrating Hair: A Case Confused with Cutaneous Larva Migrans

Journal Article Pediatric Dermatology · November 2010 Full text Cite

SCD14, SICAM-1, AND SVCAM-1 CORRELATE WITH NEUROCOGNITIVE FUNCTION IN YOUTH WITH HIV

Conference HIV infection affects cognitive performance through immune activation and related mechanisms. We hypothesized that in youth with HIV (YWH), biomarkers of macrophage activation and vascular injury are associated with impairment in distinct neurocognitive do ... Cite