Jun Ren | Scholars@Duke

Jun Ren
Visiting Scholar in the Comprehensive Cancer Center

Jun Ren MD, PhD joined Duke University as faculty from 2008. He has actively worked with Professor Kim Lyerly to create the global cancer programs featured on education and research on cancer immunotherapy and cancer vaccines program. They have been keeping pursuing to set up the win-to-win platform thought overcoming these differences and difficulties between US and China since 2008. He and Kim Lyerly secured the transitional research for cancer immunotherapy and achieved clinical research success and expand the global academic prospectives of Duke University.

Current Research Interests

Translational driven cancer therapeutic improvements featured by cancer immunotherapy and adoptive T cell immunotherapy.Identifications of new epitopes identifying the responsive T cells.

Current Appointments & Affiliations

Visiting Scholar in the Comprehensive Cancer Center, Duke Cancer Institute, Institutes and Centers 2008

Contact Information

203 Research Drive Room 433, Box 2606, Durham, NC 27710
Box 2606 Med Ctr, Durham, NC 27710
jun.ren@duke.edu (919) 684-6408

Expertise
Global Scholarship
- Research
  - United States of America (Country)
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Song, Linan, Shuo Wang, Tong Fang, Xiaoguang Qiu, Xiaoli Wang, Xinna Zhou, Michael A. Morse, et al. “Changes in Peripheral Blood Regulatory T Cells and IL-6 and IL-10 Levels Predict Response of Pediatric Medulloblastoma and Germ Cell Tumors With Residual or Disseminated Disease to Craniospinal Irradiation.” Int J Radiat Oncol Biol Phys 111, no. 2 (October 1, 2021): 479–90. https://doi.org/10.1016/j.ijrobp.2021.04.041.
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  - Wang, Xiaoli, Guoliang Qiao, Ni Jiang, Michael A. Morse, Xinna Zhou, Shuo Wang, Jiangping Wu, et al. “Serial assessment of circulating T lymphocyte phenotype and receptor repertoire during treatment of non-muscle invasive bladder cancer with adoptive T cell immunotherapy.” Am J Cancer Res 11, no. 4 (2021): 1709–18.
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  - Yang, Duo, Xiaoli Wang, Xinna Zhou, Jing Zhao, Huabing Yang, Shuo Wang, Michael A. Morse, et al. “Blood microbiota diversity determines response of advanced colorectal cancer to chemotherapy combined with adoptive T cell immunotherapy.” Oncoimmunology 10, no. 1 (2021): 1976953. https://doi.org/10.1080/2162402X.2021.1976953.
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  - Wang, Shuo, Xiaoli Wang, Xinna Zhou, Herbert Kim Lyerly, Michael A. Morse, and Jun Ren. “DC-CIK as a widely applicable cancer immunotherapy.” Expert Opin Biol Ther 20, no. 6 (June 2020): 601–7. https://doi.org/10.1080/14712598.2020.1728250.
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  - He, Zixuan, Shuo Wang, Guoliang Qiao, Xiaoli Wang, Xinna Zhou, Siyu Zhu, Yanhua Yuan, et al. “Clinical efficacy of intra-cavitary infusions of autologous dendritic cell/cytokine-induced killer cell products for the treatment of refractory malignant pleural effusions and ascites.” Am J Transl Res 12, no. 7 (2020): 3940–52.
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  - Wang, Shuo, Yuguang Song, Michael A. Morse, Pingping Sun, Guoliang Qiao, Xiaoli Wang, Xinna Zhou, Amy Hobeika, Jun Ren, and Herbert Kim Lyerly. “Infiltration of metastatic lymph nodes with PD-1+ T cells is associated with improved disease-free and overall survival in resected N+ NSCLC.” Am J Cancer Res 10, no. 12 (2020): 4435–49.
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  - Zhou, Xinna, Guoliang Qiao, Jun Ren, Xiaoli Wang, Shuo Wang, Siyu Zhu, Yanhua Yuan, Michael A. Morse, Amy Hobeika, and Herbert Kim Lyerly. “Adoptive immunotherapy with autologous T-cell infusions reduces opioid requirements in advanced cancer patients.” Pain 161, no. 1 (January 2020): 127–34. https://doi.org/10.1097/j.pain.0000000000001702.
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  - Huang, Lefu, Guoliang Qiao, Michael A. Morse, Xiaoli Wang, Xinna Zhou, Jiangping Wu, Amy Hobeika, Jun Ren, and Herbert K. Lyerly. “Predictive significance of T cell subset changes during ex vivo generation of adoptive cellular therapy products for the treatment of advanced non-small cell lung cancer.” Oncol Lett 18, no. 6 (December 2019): 5717–24. https://doi.org/10.3892/ol.2019.10964.
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  - Zhao, Xia, Yanping Li, Xiaoli Wang, Jiangping Wu, Yanhua Yuan, Shuzhen Lv, and Jun Ren. “Synergistic association of FOXP3+ tumor infiltrating lymphocytes with CCL20 expressions with poor prognosis of primary breast cancer: A retrospective cohort study.” Medicine (Baltimore) 98, no. 50 (December 2019): e18403. https://doi.org/10.1097/MD.0000000000018403.
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  - Qiao, Guoliang, Xiaoli Wang, Xinna Zhou, Michael A. Morse, Jiangping Wu, Shuo Wang, Yuguang Song, et al. “Immune correlates of clinical benefit in a phase I study of hyperthermia with adoptive T cell immunotherapy in patients with solid tumors.” Int J Hyperthermia 36, no. sup1 (November 2019): 74–82. https://doi.org/10.1080/02656736.2019.1647350.
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  - Lv, Shuzhen, Shuo Wang, Guoliang Qiao, Xiaoli Wang, Xinna Zhou, Fengcai Yan, Yanping Li, et al. “Functional CD3+CD8+PD1- T Cell Accumulation and PD-L1 Expression Increases During Tumor Invasion in DCIS of the Breast.” Clin Breast Cancer 19, no. 5 (October 2019): e617–23. https://doi.org/10.1016/j.clbc.2019.04.001.
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  - Sun, Yuanyuan, Suya Wang, Hainan Yang, Jiangping Wu, Sha Li, Guoliang Qiao, Shuo Wang, et al. “Impact of synchronized anti-PD-1 with Ad-CEA vaccination on inhibition of colon cancer growth.” Immunotherapy 11, no. 11 (August 2019): 953–66. https://doi.org/10.2217/imt-2019-0055.
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  - Zhao, Y., G. Qiao, X. Wang, Y. Song, X. Zhou, N. Jiang, L. Zhou, et al. “Combination of DC/CIK adoptive T cell immunotherapy with chemotherapy in advanced non-small-cell lung cancer (NSCLC) patients: a prospective patients' preference-based study (PPPS).” Clin Transl Oncol 21, no. 6 (June 2019): 721–28. https://doi.org/10.1007/s12094-018-1968-3.
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  - Wang, Xiaoli, Shuo Wang, Michael A. Morse, Ni Jiang, Yanjie Zhao, Yuguang Song, Lei Zhou, et al. “Prospective randomized comparative study on rivaroxaban and LMWH for prophylaxis of post-apheresis thrombosis in adoptive T cell immunotherapy cancer patients.” J Thromb Thrombolysis 47, no. 4 (May 2019): 505–11. https://doi.org/10.1007/s11239-019-01844-7.
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  - Qiao, Guoliang, Xiaoli Wang, Lei Zhou, Xinna Zhou, Yuguang Song, Shuo Wang, Lei Zhao, et al. “Autologous Dendritic Cell-Cytokine Induced Killer Cell Immunotherapy Combined with S-1 Plus Cisplatin in Patients with Advanced Gastric Cancer: A Prospective Study.” Clin Cancer Res 25, no. 5 (March 1, 2019): 1494–1504. https://doi.org/10.1158/1078-0432.CCR-18-2360.
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  - Lyerly, H Kim, Jun Ren, Renzo Canetta, Gi Hyun Kim, Sumimasa Nagai, Tomohiro Yamaguchi, Ken Hatogai, et al. “Global Development of Anticancer Therapies for Rare Cancers, Pediatric Cancers, and Molecular Subtypes of Common Cancers.” J Glob Oncol 4 (December 2018): 1–11. https://doi.org/10.1200/JGO.18.00092.
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  - Zhou, Xinna, Guoliang Qiao, Xiaoli Wang, Qingkun Song, Michael A. Morse, Amy Hobeika, William R. Gwin, Jun Ren, and H Kim Lyerly. “CYP1A1 genetic polymorphism is a promising predictor to improve chemotherapy effects in patients with metastatic breast cancer treated with docetaxel plus thiotepa vs. docetaxel plus capecitabine.” Cancer Chemother Pharmacol 81, no. 2 (February 2018): 365–72. https://doi.org/10.1007/s00280-017-3500-9.
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  - Song, Qingkun, Jun Ren, Xinna Zhou, Xiaoli Wang, Guohong Song, Amy Hobeika, Yanhua Yuan, and Herbert Kim Lyerly. “Circulating CD8+CD28- suppressor T cells tied to poorer prognosis among metastatic breast cancer patients receiving adoptive T-cell therapy: A cohort study.” Cytotherapy 20, no. 1 (January 2018): 126–33. https://doi.org/10.1016/j.jcyt.2017.08.018.
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  - Jiang, Ni, Guoliang Qiao, Xiaoli Wang, Michael A. Morse, William R. Gwin, Lei Zhou, Yuguang Song, et al. “Dendritic Cell/Cytokine-Induced Killer Cell Immunotherapy Combined with S-1 in Patients with Advanced Pancreatic Cancer: A Prospective Study.” Clin Cancer Res 23, no. 17 (September 1, 2017): 5066–73. https://doi.org/10.1158/1078-0432.CCR-17-0492.
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  - Zhang, Yanbin, Yue Liu, Yingjiang Ye, Danhua Shen, Hui Zhang, Hongyan Huang, Sha Li, Shan Wang, and Jun Ren. “Quantitative proteome analysis of colorectal cancer-related differential proteins.” J Cancer Res Clin Oncol 143, no. 2 (February 2017): 233–41. https://doi.org/10.1007/s00432-016-2274-5.
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  - Zhou, L., L. -. C. Zhao, N. Jiang, X. -. L. Wang, X. -. N. Zhou, X. -. L. Luo, and J. Ren. “MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2.” Eur Rev Med Pharmacol Sci 21, no. 1 (January 2017): 87–94.
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  - Ren, Jun, William R. Gwin, Xinna Zhou, Xiaoli Wang, Hongyan Huang, Ni Jiang, Lei Zhou, et al. “Adaptive T cell responses induced by oncolytic Herpes Simplex Virus-granulocyte macrophage-colony-stimulating factor therapy expanded by dendritic cell and cytokine-induced killer cell adoptive therapy.” Oncoimmunology 6, no. 4 (2017): e1264563. https://doi.org/10.1080/2162402X.2016.1264563.
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  - Wang, X., J. Ren, J. Zhang, Y. Yan, N. Jiang, J. Yu, L. Di, et al. “Prospective study of cyclophosphamide, thiotepa, carboplatin combined with adoptive DC-CIK followed by metronomic cyclophosphamide therapy as salvage treatment for triple negative metastatic breast cancers patients (aged <45).” Clin Transl Oncol 18, no. 1 (January 2016): 82–87. https://doi.org/10.1007/s12094-015-1339-2.
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  - Song, Qing-Kun, Jun Ren, Xin-Na Zhou, Xiao-Li Wang, Guo-Hong Song, Li-Jun Di, Jing Yu, et al. “The prognostic value of peripheral CD4+CD25+ T lymphocytes among early stage and triple negative breast cancer patients receiving dendritic cells-cytokine induced killer cells infusion.” Oncotarget 6, no. 38 (December 1, 2015): 41350–59. https://doi.org/10.18632/oncotarget.5534.
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  - Song, Qingkun, Xinna Zhou, Jing Yu, Ningning Dong, Xiaoli Wang, Huabing Yang, Jun Ren, and H Kim Lyerly. “The prognostic values of CYP2B6 genetic polymorphisms and metastatic sites for advanced breast cancer patients treated with docetaxel and thiotepa.” Sci Rep 5 (November 25, 2015): 16775. https://doi.org/10.1038/srep16775.
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  - Zhou, Xinna, Xiaoli Wang, Qingkun Song, Huabing Yang, Xishan Zhu, Jing Yu, Guohong Song, et al. “Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy.” Int J Clin Pharmacol Ther 53, no. 11 (November 2015): 914–22. https://doi.org/10.5414/CP202391.
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  - Song, Qing-Kun, Xiao-Li Wang, Xin-Na Zhou, Hua-Bing Yang, Yu-Chen Li, Jiang-Ping Wu, Jun Ren, and Herbert Kim Lyerly. “Breast Cancer Challenges and Screening in China: Lessons From Current Registry Data and Population Screening Studies.” Oncologist 20, no. 7 (July 2015): 773–79. https://doi.org/10.1634/theoncologist.2014-0351.
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  - Lyerly, H Kim, Maria R. Fawzy, Zeba Aziz, Reena Nair, C. S. Pramesh, Vani Parmar, Purvish M. Parikh, et al. “Regional variation in identified cancer care needs of early-career oncologists in China, India, and Pakistan.” Oncologist 20, no. 5 (May 2015): 532–38. https://doi.org/10.1634/theoncologist.2014-0213.
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  - Huang, H. Y., A. Chen, T. Wang, M. N. Wang, X. K. Ning, M. F. He, Y. Z. Hu, et al. “Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining.” Oncotarget 6 (2015): 20278–87.
  - Lu, M., L. Zhou, X. H. Zheng, Y. Quan, X. L. Wang, X. N. Zhou, and J. Ren. “A novel molecular marker of breast cancer stem cells identified by cell-SELEX method.” Cancer Biomarkers 15 (2015): 163–70. https://doi.org/10.3233/cbm-140450.
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  - Song, Q. K., L. Zhao, J. Li, and J. Ren. “Fruit Consumption Reduces the Risk of Esophageal Cancer in Yanting, People's Republic of China.” Asia Pacific Journal of Public Health 27 (2015): 469–75. https://doi.org/10.1177/1010539514551199.
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  - Zhao, Yan-Jie, Ni Jiang, Qing-Kun Song, Jiang-Ping Wu, Yu-Guang Song, Hong-Mei Zhang, Feng Chen, et al. “Continuous DC-CIK infusions restore CD8+ cellular immunity, physical activity and improve clinical efficacy in advanced cancer patients unresponsive to conventional treatments.” Asian Pac J Cancer Prev 16, no. 6 (2015): 2419–23. https://doi.org/10.7314/apjcp.2015.16.6.2419.
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  - Cha, N. E., W. Liu, N. Yang, S. Z. Xie, Y. W. Gao, X. Chen, X. L. Wang, and J. Ren. “Oncogenicity of LHX4 in colorectal cancer through Wnt/beta-catenin/TCF4 cascade.” Tumor Biology 35 (2014): 10319–24. https://doi.org/10.1007/s13277-014-2210-8.
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  - Jiang, Ni, Xishan Zhu, Hongmei Zhang, Xiaoli Wang, Xinna Zhou, Jiezhun Gu, Baoan Chen, and Jun Ren. “The relationship between methylenetetrahydrofolate reductase polymorphism and hematological malignancy.” Clin Lab 60, no. 5 (2014): 767–74. https://doi.org/10.7754/clin.lab.2013.130447.
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  - Song, Q. K., D. C. Christiani, X. R. Wang, and J. Ren. “The Global Contribution of Outdoor Air Pollution to the Incidence, Prevalence, Mortality and Hospital Admission for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.” International Journal of Environmental Research and Public Health 11 (2014): 11822–32. https://doi.org/10.3390/ijerph111111822.
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  - Zhu, X. S., H. J. Yu, B. X. He, X. N. Zhou, N. Jiang, H. M. Zhang, X. L. Wang, and J. Ren. “Mouse Flk-1(+) Sca-1(-) Mesenchymal Stem Cells: Functional Plasticity In Vitro and Immunoregulation In Vivo.” Transplantation 97 (2014): 509–17. https://doi.org/10.1097/01.tp.0000442775.46133.38.
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  - Ren, Jun, Lijun Di, Guohong Song, Jing Yu, Jun Jia, Yuling Zhu, Ying Yan, et al. “Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free and overall survival in patients with metastatic breast cancer: reargument of such contentious therapeutic preferences.” Clin Transl Oncol 15, no. 10 (October 2013): 780–88. https://doi.org/10.1007/s12094-013-1001-9.
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  - Song, Guohong, Xiaoli Wang, Jun Jia, Yanhua Yuan, Fengling Wan, Xinna Zhou, Huabing Yang, Jun Ren, Jiezhun Gu, and Herbert Kim Lyerly. “Elevated level of peripheral CD8(+)CD28(-) T lymphocytes are an independent predictor of progression-free survival in patients with metastatic breast cancer during the course of chemotherapy.” Cancer Immunol Immunother 62, no. 6 (June 2013): 1123–30. https://doi.org/10.1007/s00262-013-1424-8.
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  - Liang, Xu, Jie Zhang, Yulin Zhu, Yuanli Lu, Xinna Zhou, Zheng Wang, Jing Yu, et al. “Specific genetic polymorphisms of IL10-592 AA and IL10-819 TT genotypes lead to the key role for inducing docetaxel-induced liver injury in breast cancer patients.” Clin Transl Oncol 15, no. 4 (April 2013): 331–34. https://doi.org/10.1007/s12094-012-0936-6.
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  - Sun, Hongmei, Jun Jia, Xiaoli Wang, Bo Ma, Lijun Di, Guohong Song, and Jun Ren. “CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties.” Clin Transl Oncol 15, no. 1 (January 2013): 46–54. https://doi.org/10.1007/s12094-012-0891-2.
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  - Zhu, X. S., X. N. Zhou, B. X. He, and J. Ren. “Impaired immunomodulatory function of chronic myeloid leukemia cancer stem cells and the possible mechanism involved in it.” Cancer Immunology Immunotherapy 62 (2013): 689–703. https://doi.org/10.1007/s00262-012-1367-5.
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  - Zhu, X. S., B. X. He, X. N. Zhou, and J. Ren. “Comparison of the effects of human adipose and bone marrow mesenchymal stem cells on T lymphocytes.” Cell Biology International 37 (2013): 11–18. https://doi.org/10.1002/cbin.10002.
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  - Zhu, X. S., B. X. He, X. N. Zhou, and J. Ren. “Effects of transplanted bone-marrow-derived mesenchymal stem cells in animal models of acute hepatitis.” Cell and Tissue Research 351 (2013): 477–86. https://doi.org/10.1007/s00441-012-1524-3.
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  - Ma, Bo, Hanfang Jiang, Jun Jia, Lijun Di, Guohong Song, Jing Yu, Yulin Zhu, et al. “Murine bone marrow stromal cells pulsed with homologous tumor-derived exosomes inhibit proliferation of liver cancer cells.” Clin Transl Oncol 14, no. 10 (October 2012): 764–73. https://doi.org/10.1007/s12094-012-0860-9.
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  - Cao, Baoshan, Jun Jia, Liwen Ma, Lijun Di, Guohong Song, Yanhua Yuan, Bo Ma, et al. “Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells.” Clin Transl Oncol 14, no. 8 (August 2012): 575–85. https://doi.org/10.1007/s12094-012-0844-9.
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  - Wang, Zheng, Xu Liang, Jing Yu, Xiaohui Zheng, Yulin Zhu, Ying Yan, Ningning Dong, et al. “Non-genetic risk factors and predicting efficacy for docetaxel--drug-induced liver injury among metastatic breast cancer patients.” J Gastroenterol Hepatol 27, no. 8 (August 2012): 1348–52. https://doi.org/10.1111/j.1440-1746.2012.07131.x.
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  - Di, L. J., Y. L. Zhu, J. Jia, J. Yu, G. H. Song, J. Zhang, L. Che, et al. “Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients.” Clinical & Translational Oncology 14 (2012): 675–81. https://doi.org/10.1007/s12094-012-0854-7.
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  - Che, L., Y. H. Yuan, J. Jia, and J. Ren. “Activation of sonic hedgehog signaling pathway is an independent potential prognosis predictor in human hepatocellular carcinoma patients.” Chinese Journal of Cancer Research 24 (2012): 323–31. https://doi.org/10.3978/j.issn.1000-9604.2012.10.10.
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  - Dong, N. N., J. Yu, C. Y. Wang, X. H. Zheng, Z. Wang, L. J. Di, G. H. Song, et al. “Pharmacogenetic assessment of clinical outcome in patients with metastatic breast cancer treated with docetaxel plus capecitabine.” Journal of Cancer Research and Clinical Oncology 138 (2012): 1197–1203. https://doi.org/10.1007/s00432-012-1183-5.
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  - Lin, X. L., X. L. Wang, B. Ma, J. Jia, Y. Yan, L. J. Di, Y. H. Yuan, et al. “HER2-specific T lymphocytes kill both trastuzumab-resistant and trastuzumab-sensitive breast cell lines in vitro.” Chinese Journal of Cancer Research 24 (2012): 143–50. https://doi.org/10.1007/s11670-012-0143-6.
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  - Quan, Y., Y. Yan, X. L. Wang, Q. B. Fu, W. K. Wang, J. W. Wu, G. Yang, J. Ren, and Y. G. Wang. “Impact of cell dissociation on identification of breast cancer stem cells.” Cancer Biomarkers 12 (2012): 125–33. https://doi.org/10.3233/cbm-130300.
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  - Song, G. H., J. Ren, A. Stojadinovic, W. Chen, Z. Sahab, S. W. Fu, and Y. G. Man. “Conjunction of tumor cells with lymphocytes: Implications for tumor invasion and metastasis.” Cancer Epidemiology 36 (2012): 354–63. https://doi.org/10.1016/j.canep.2011.12.006.
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  - Yu, J., J. Ren, L. J. Di, G. H. Song, Y. L. Zhu, J. Zhang, X. Liang, et al. “Mobilization of Peripheral Blood Stem Cells Using Regimen Combining Docetaxel with Granulocyte Colony-stimulating Factor in Breast Cancer Patients.” Chinese Journal of Cancer Research 23 (2011): 49–53. https://doi.org/10.1007/s11670-011-0049-8.
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  - Cheng, J. P., Y. Yan, X. Y. Wang, Y. L. Lu, Y. H. Yuan, X. L. Wang, J. Jia, and J. Ren. “Circulating Tumor Cells in Metastatic Breast Cancer: Monitoring Response to Chemotherapy and Predicting Progression-Free Survival.” Chinese Journal of Cancer Research 22 (2010): 201–10. https://doi.org/10.1007/s11670-010-0201-x.
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  - Song, G. H., J. Ren, L. J. Di, J. Yu, J. Zhang, B. Shao, J. Jia, and W. Sun. “Decrease of peripheral blood CD8+/CD28-suppressor T cell followed by dentritic cells immunomodulation among metastatic breast cancer patients.” Chinese Journal of Cancer Research 22 (2010): 310–15. https://doi.org/10.1007/s11670-010-0310-6.
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  - Song, G. H., J. Ren, L. J. Zhang, L. J. Di, Y. H. Yuan, J. Yu, and J. Jia. “Low correspondence of EGFR mutations in tumor tissue and paired serum of non-small-cell lung cancer patients.” Chinese Journal of Cancer Research 22 (2010): 27–31. https://doi.org/10.1007/s11670-010-0027-6.
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  - Zhang, L., J. Ren, K. F. Pan, J. L. Ma, J. Y. Li, L. Shen, X. D. Zhang, et al. “Detection of gastric carcinoma-associated MG7-Ag by serum immuno-PCR assay in a high-risk Chinese population, with implication for screening.” International Journal of Cancer 126 (2010): 469–73. https://doi.org/10.1002/ijc.24739.
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  - Zhu, B. D., X. L. Li, Y. Liu, J. Chang, D. D. Zhang, Q. A. Wang, J. Ren, and C. P. Cui. “Involvement of Hepatopoietin Cn in the development of human hepatocellular carcinoma.” Clinical & Experimental Metastasis 27 (2010): 571–80. https://doi.org/10.1007/s10585-010-9346-8.
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  - Ren, J., J. Jia, H. M. Zhang, L. W. Zhang, B. Ma, H. F. Jiang, L. J. Di, G. H. Song, and J. Yu. “Dendritic cells pulsed with alpha-fetoprotein and mutant P53 fused gene induce bi-targeted cytotoxic T lymphocyte response against hepatic carcinoma.” Cancer Science 99 (2008): 1420–26. https://doi.org/10.1111/j.1349-7006.2008.00820.x.
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  - Zhang, Xiaotian, Masakazu Yashiro, Masaichi Ohira, Jun Ren, and Kosei Hirakawa. “Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.” Cancer Sci 97, no. 9 (September 2006): 938–44. https://doi.org/10.1111/j.1349-7006.2006.00253.x.
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  - Zhang, X. T., M. Yashiro, J. Ren, and K. Hirakawa. “Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines.” Oncology Reports 16 (2006): 563–68.
  - Yang, J. Y., D. Y. Cao, W. C. Liu, H. M. Zhang, Z. H. Teng, and J. Ren. “Dendritic cell generated from CD34+hematopoietic progenitors can be transfected with adenovirus containing gene of HBsAg and induce antigen-specific cytotoxic T cell responses.” Cellular Immunology 240 (2006): 14–21. https://doi.org/10.1016/j.cellimm.2006.06.005.
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  - Zhang, H. M., L. W. Zhang, J. Ren, L. Fan, X. M. Si, and W. C. Liu. “Induction of alpha-fetoprotein-specific CD4-and CD8-mediated T-cell response using RNA-transfected dendritic cells.” Cellular Immunology 239 (2006): 144–50. https://doi.org/10.1016/j.cellimm.2006.05.004.
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  - Zhang, H. M., L. W. Zhang, W. C. Liu, J. Cheng, X. M. Si, and J. Ren. “Comparative analysis of DC fused with tumor cells or transfected with tumor total RNA as potential cancer vaccines against hepatocellular carcinoma.” Cytotherapy 8 (2006): 580–88. https://doi.org/10.1080/14653240600991353.
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  - Fan, L., W. C. Liu, Y. J. Zhang, J. Ren, B. R. Pan, D. H. Liu, Y. Chen, and Z. C. Yu. “Oral Xeloda plus bi-platinu two-way combined chemotherapy in treatment of advanced gastrointestinal malignancies.” World Journal of Gastroenterology 11 (2005): 4300–4304.
  - Zhang, L. W., H. M. Zhang, W. C. Liu, H. Wang, J. Jia, X. M. Si, and J. Ren. “Specific antihepatocellular carcinoma T cells generated by dendritic cells pulsed with hepatocellular carcinoma cell line HepG2 total RNA.” Cellular Immunology 238 (2005): 61–66. https://doi.org/10.1016/j.cellimm.2006.01.003.
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  - Huang, X. F., C. M. Wang, B. R. Pan, X. W. Dai, L. Fang, J. J. Yang, H. Yu, and J. Ren. “Pathological characteristics of gastric leiomyoblastoma.” World Journal of Gastroenterology 10 (2004): 3182–84.
  - Wan, Y., Y. Y. Xu, J. H. Jiang, F. S. Kong, F. B. Xue, Y. X. Bai, B. R. Pan, J. Ren, and D. M. Fan. “Chinese literature associated with diagnosis of Helicobacter pylori.” World Journal of Gastroenterology 10 (2004): 231–33.
  - Wang, H. D., J. Ren, and L. Zhang. “CDH1 germline mutation in hereditary gastric carcinoma.” World Journal of Gastroenterology 10 (2004): 3088–93.
  - Zhang, L. W., J. Ren, L. Zhang, H. M. Zhang, B. Jin, B. R. Pan, X. M. Si, et al. “Construction and expression of recombined human AFP eukaryotic expression vector.” World Journal of Gastroenterology 9 (2003): 1465–68.
  - Ren, J., W. C. Liu, L. Ge, D. M. Fan, and X. Yong. “Detection of circulating gastric cancer associated antigen MG7-Ag in human sera with McAb and bispecific ScFv-streptavidin fusion protein-based immuno-PCR technique.” Clinical Chemistry 47 (2001): 366–366.
  - Xue, F. B., Y. Y. Xu, Y. Wan, B. R. Pan, J. Ren, and D. M. Fan. “Association of H-pylori infection with gastric carcinoma: a Meta analysis.” World Journal of Gastroenterology 7 (2001): 801–4.
  - Ren, J., L. Ge, Y. Q. Li, J. Bai, W. C. Liu, and X. M. Si. “Detection of circulating CEA molecules in human sera and leukopheresis of peripheral blood stem cells with E. coli expressed bispecific CEAScFv-streptavidin fusion protein-based immuno-PCR technique.” Edited by Y. M. D. Lo, R. W. K. Chiu, and P. J. Johnson. Ann.Ny Acad.Sci., 2001, 116–18.
  - Ren, J., Z. Chen, S. J. Zhou, X. Y. Zhang, B. R. Pan, and D. M. Fan. “Detection of circulating gastric carcinoma-associated antigen MG7-Ag in human sera using an established single determinant immuno-polymerase chain reaction technique.” Cancer 88 (2000): 280–85.
- Conference Papers
  - Song, Qingkun, Jun Ren, Jing Yu, Xiaoli Wang, Xinna Zhou, and Herbert Kim Lyerly. “Abstract 3417: Peripheral CD8+CD28-suppressive T lymphocytes act as a prognosticator among breast cancer patients with adoptive T-cell immunotherapy.” In Cancer Research, 76:3417–3417. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.am2016-3417.
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  - Yu, Jing, Ningning Dong, Ying Yan, Bin Shao, Lijun Di, Guohong Song, Li Che, et al. “Abstract 5298: Two distinctive single nucleotide polymorphisms determine liver metastases responses to docetaxel plus thiotepa for metastatic breast cancer patients.” In Cancer Research, 73:5298–5298. American Association for Cancer Research (AACR), 2013. https://doi.org/10.1158/1538-7445.am2013-5298.
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Conference Papers