Konstantin Arbeev
Associate Research Professor in the Social Science Research Institute
Konstantin G. Arbeev received the M.S. degree in Applied Mathematics from Moscow State University (branch in Ulyanovsk, Russia) in 1995 and the Ph.D. degree in Mathematics and Physics (specialization in Theoretical Foundations of Mathematical Modeling, Numerical Methods and Programming) from Ulyanovsk State University (Russia) in 1999. He was a post-doctoral fellow in Max Planck Institute for Demographic Research in Rostock (Germany) before moving to Duke University in 2004 to work as a Research Scientist and a Senior Research Scientist in the Department of Sociology and the Social Science Research Institute (SSRI). He is currently an Associate Research Professor in SSRI. Dr. Arbeev's major research interests are related to three interconnected fields of biodemography, biostatistics and genetic epidemiology as pertains to research on aging. The focus of his research is on discovering genetic and non-genetic factors that can affect the process of aging and determine longevity and healthy lifespan. He is interested in both methodological advances in this research area as well as their practical applications to analyses of large-scale longitudinal studies with phenotypic, genetic and, recently, genomic information. Dr. Arbeev authored and co-authored more than 150 peer-reviewed publications in these areas.
Current Appointments & Affiliations
- Associate Research Professor in the Social Science Research Institute, Social Science Research Institute, University Institutes and Centers 2017
Contact Information
- 2024 W. Main Street, Room A102f, Durham, NC 27705
- Box 90420, Durham, NC 27708
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ka29@duke.edu
(919) 668-2707
- Background
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Education, Training, & Certifications
- Ph.D., Ulyanovsk State University (Russia) 1999
- Research
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Selected Grants
- Leveraging population-based human data to uncover mechanisms connecting Alzheimer's disease and common infections and facilitate vaccines repurposing for AD prevention awarded by National Institutes of Health 2021 - 2026
- Dissecting genetic and non-genetic heterogeneity in predisposition to Alzheimer's disease and vascular traits in pleiotropic context awarded by National Institutes of Health 2020 - 2025
- Personalized genetic profiles of risk and resilience in Alzheimer's and vascular diseases awarded by National Institutes of Health 2020 - 2025
- Understanding Alzheimer's Disease in the Context of the Aging awarded by National Institutes of Health 2019 - 2024
- Genetics of aging, health and longevity: focus on regulatory mechanisms and functional variants connecting aging and Alzheimer's disease" awarded by National Institutes of Health 2020 - 2024
- Analysis: The Long Life Family Study awarded by Washington University in St. Louis 2019 - 2024
- Project 1: The Long Life Family Study awarded by Washington University in St. Louis 2019 - 2024
- ApoE2 and protective molecular signatures in Alzheimer's disease and aging awarded by National Institutes of Health 2018 - 2023
- Genetics of changes in population pyramids: Implications for health forecasting with a focus on Alzheimer's Disease and related dementias awarded by National Institute on Aging 2014 - 2023
- Functional Aging in Health and Disease - the COmPLETE Project awarded by University of Basel 2020
- Long Life Family Study: Duke Univ./Univ. of Southern Denmark Field Center awarded by National Institutes of Health 2004 - 2019
- Causal Effects of Time-Dependent Treatment: Optimizing Care of Cancer Patients awarded by National Institutes of Health 2013 - 2015
- Integrating Population and Basic Science in Cancer Research awarded by National Institutes of Health 2009 - 2015
- The Future of Major Geriatric Disorders in the US Elderly awarded by National Institutes of Health 2008 - 2013
- Evaluating New Genetic Effects on Health and Aging from Longitudinal Data awarded by National Institutes of Health 2007 - 2013
- New Methods of Studying Aging, Health and Longevity: Combining Longitudinal Data awarded by National Institutes of Health 2009 - 2011
- Healthy Life at Risk: The Role of Senesence awarded by National Institutes of Health 2005 - 2011
- missing activity
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External Relationships
- Lab Me Analytics
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Song, Zeyuan, Anastasia Gurinovich, Marianne Nygaard, Jonas Mengel-From, Stacy Andersen, Stephanie Cosentino, Nicole Schupf, et al. “Rare genetic variants correlate with better processing speed.” Neurobiology of Aging 125 (May 2023): 115–22. https://doi.org/10.1016/j.neurobiolaging.2022.11.018.Full Text
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Akushevich, I., A. Yashkin, M. Kovtun, J. Kravchenko, K. Arbeev, and A. I. Yashin. “Forecasting prevalence and mortality of Alzheimer's disease using the partitioning models.” Exp Gerontol 174 (April 2023): 112133. https://doi.org/10.1016/j.exger.2023.112133.Full Text Link to Item
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Arbeev, Konstantin G., Olivia Bagley, Arseniy P. Yashkin, Hongzhe Duan, Igor Akushevich, Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “Understanding Alzheimer's disease in the context of aging: Findings from applications of stochastic process models to the Health and Retirement Study.” Mechanisms of Ageing and Development 211 (April 2023): 111791. https://doi.org/10.1016/j.mad.2023.111791.Full Text
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Bae, Harold, Anastasia Gurinovich, Tanya T. Karagiannis, Zeyuan Song, Anastasia Leshchyk, Mengze Li, Stacy L. Andersen, et al. “A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.” International Journal of Molecular Sciences 24, no. 1 (December 2022): 116. https://doi.org/10.3390/ijms24010116.Full Text
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Kulminski, Alexander M., Ethan Jain-Washburn, Ian Philipp, Liang He, Yury Loika, Elena Loiko, Olivia Bagley, et al. “APOE ɛ4 allele and TOMM40-APOC1 variants jointly contribute to survival to older ages.” Aging Cell 21, no. 12 (December 2022): e13730. https://doi.org/10.1111/acel.13730.Full Text
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Galvin, Angéline, Mary Feitosa, Konstantin Arbeev, Allison L. Kuipers, Mary Wojczynski, Svetlana Ukrainsteva, and Kaare Christensen. “Physical resilience after a diagnosis of cardiovascular disease among offspring of long-lived siblings.” European Journal of Ageing 19, no. 3 (September 2022): 437–45. https://doi.org/10.1007/s10433-021-00641-7.Full Text
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Nazarian, Alireza, Konstantin G. Arbeev, Arseniy P. Yashkin, and Alexander M. Kulminski. “Genome-wide analysis of genetic predisposition to common polygenic cancers.” Journal of Applied Genetics 63, no. 2 (May 2022): 315–25. https://doi.org/10.1007/s13353-021-00679-4.Full Text
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Anderson, James J., Ezra Susser, Konstantin G. Arbeev, Anatoliy I. Yashin, Daniel Levy, Simon Verhulst, and Abraham Aviv. “Telomere-length dependent T-cell clonal expansion: A model linking ageing to COVID-19 T-cell lymphopenia and mortality.” Ebiomedicine 78 (April 2022): 103978. https://doi.org/10.1016/j.ebiom.2022.103978.Full Text
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Gurinovich, Anastasia, Mengze Li, Anastasia Leshchyk, Harold Bae, Zeyuan Song, Konstantin G. Arbeev, Marianne Nygaard, Mary F. Feitosa, Thomas T. Perls, and Paola Sebastiani. “Evaluation of GENESIS, SAIGE, REGENIE and fastGWA-GLMM for genome-wide association studies of binary traits in correlated data.” Frontiers in Genetics 13 (January 2022): 897210. https://doi.org/10.3389/fgene.2022.897210.Full Text
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Anderson, James J., Ezra Susser, Konstantin G. Arbeev, Anatoliy I. Yashin, Daniel Levy, Simon Verhulst, and Abraham Aviv. “Short Telomeres and a T-Cell Shortfall in COVID-19: The Aging Effect.” Medrxiv, July 10, 2021. https://doi.org/10.1101/2021.05.19.21257474.Full Text Link to Item
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Yashin, Anatoliy I., Deqing Wu, Konstantin Arbeev, Olivia Bagley, Igor Akushevich, Matt Duan, Arseniy Yashkin, and Svetlana Ukraintseva. “Interplay between stress-related genes may influence Alzheimer's disease development: The results of genetic interaction analyses of human data.” Mechanisms of Ageing and Development 196 (June 2021): 111477. https://doi.org/10.1016/j.mad.2021.111477.Full Text
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Ukraintseva, Svetlana, Konstantin Arbeev, Matt Duan, Igor Akushevich, Alexander Kulminski, Eric Stallard, and Anatoliy Yashin. “Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity.” Mechanisms of Ageing and Development 194 (March 2021): 111418. https://doi.org/10.1016/j.mad.2020.111418.Full Text
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Ukraintseva, Svetlana, Matt Duan, Konstantin Arbeev, Deqing Wu, Olivia Bagley, Arseniy P. Yashkin, Galina Gorbunova, Igor Akushevich, Alexander Kulminski, and Anatoliy Yashin. “Interactions Between Genes From Aging Pathways May Influence Human Lifespan and Improve Animal to Human Translation.” Frontiers in Cell and Developmental Biology 9 (January 2021): 692020. https://doi.org/10.3389/fcell.2021.692020.Full Text
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Yashin, Anatoliy I., Deqing Wu, Konstantin Arbeev, Arseniy P. Yashkin, Igor Akushevich, Olivia Bagley, Matt Duan, and Svetlana Ukraintseva. “Roles of interacting stress-related genes in lifespan regulation: insights for translating experimental findings to humans.” Journal of Translational Genetics and Genomics 5, no. 4 (January 2021): 357–79.
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Galvin, Angéline, Svetlana Ukraintseva, Konstantin Arbeev, Mary Feitosa, and Kaare Christensen. “Physical robustness and resilience among long-lived female siblings: a comparison with sporadic long-livers.” Aging 12, no. 14 (July 2020): 15157–68. https://doi.org/10.18632/aging.103618.Full Text
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Santanasto, Adam J., Megan M. Marron, Robert M. Boudreau, Mary F. Feitosa, Mary K. Wojczynski, Konstantin G. Arbeev, Bharat Thyagarajan, et al. “Prevalence, Incidence, and Risk Factors for Overall, Physical, and Cognitive Independence Among Those From Exceptionally Long-Lived Families: The Long Life Family Study.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 75, no. 5 (April 2020): 899–905. https://doi.org/10.1093/gerona/glz124.Full Text
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Arbeev, Konstantin G., Olivia Bagley, Svetlana V. Ukraintseva, Deqing Wu, Hongzhe Duan, Alexander M. Kulminski, Eric Stallard, et al. “Genetics of physiological dysregulation: findings from the long life family study using joint models.” Aging 12, no. 7 (April 2020): 5920–47. https://doi.org/10.18632/aging.102987.Full Text
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Kulminski, Alexander M., Leonardo Shu, Yury Loika, Alireza Nazarian, Konstantin Arbeev, Svetlana Ukraintseva, Anatoliy Yashin, and Irina Culminskaya. “APOE region molecular signatures of Alzheimer's disease across races/ethnicities.” Neurobiology of Aging 87 (March 2020): 141.e1-141.e8. https://doi.org/10.1016/j.neurobiolaging.2019.11.007.Full Text
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Arbeev, Konstantin G., Simon Verhulst, Troels Steenstrup, Jeremy D. Kark, Olivia Bagley, Charles Kooperberg, Alexander P. Reiner, et al. “Association of Leukocyte Telomere Length With Mortality Among Adult Participants in 3 Longitudinal Studies.” Jama Network Open 3, no. 2 (February 5, 2020): e200023. https://doi.org/10.1001/jamanetworkopen.2020.0023.Full Text
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Nazarian, Alireza, Konstantin G. Arbeev, and Alexander M. Kulminski. “The impact of disregarding family structure on genome-wide association analysis of complex diseases in cohorts with simple pedigrees.” Journal of Applied Genetics 61, no. 1 (February 2020): 75–86. https://doi.org/10.1007/s13353-019-00526-7.Full Text
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Arbeev, Konstantin G., Olivia Bagley, Svetlana V. Ukraintseva, Hongzhe Duan, Alexander M. Kulminski, Eric Stallard, Deqing Wu, et al. “Composite Measure of Physiological Dysregulation as a Predictor of Mortality: The Long Life Family Study.” Frontiers in Public Health 8 (January 2020): 56. https://doi.org/10.3389/fpubh.2020.00056.Full Text
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Kulminski, Alexander M., Leonardo Shu, Yury Loika, Liang He, Alireza Nazarian, Konstantin Arbeev, Svetlana Ukraintseva, Anatoliy Yashin, and Irina Culminskaya. “Genetic and regulatory architecture of Alzheimer's disease in the APOE region.” Alzheimer’S & Dementia (Amsterdam, Netherlands) 12, no. 1 (January 2020): e12008. https://doi.org/10.1002/dad2.12008.Full Text
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Wagner, Jonathan, Raphael Knaier, Karsten Königstein, Christopher Klenk, Justin Carrard, Eric Lichtenstein, Hubert Scharnagl, et al. “Composite Measures of Physical Fitness to Discriminate Between Healthy Aging and Heart Failure: The COmPLETE Study.” Frontiers in Physiology 11 (January 2020): 596240. https://doi.org/10.3389/fphys.2020.596240.Full Text
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Wagner, Jonathan, Raphael Knaier, Denis Infanger, Konstantin Arbeev, Matthias Briel, Thomas Dieterle, Henner Hanssen, et al. “Functional aging in health and heart failure: the COmPLETE Study.” Bmc Cardiovascular Disorders 19, no. 1 (July 2019): 180. https://doi.org/10.1186/s12872-019-1164-6.Full Text
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Akushevich, I., A. Yashkin, J. Kravchenko, F. Fang, K. Arbeev, F. Sloan, and A. I. Yashin. “A forecasting model of disease prevalence based on the McKendrick-von Foerster equation.” Math Biosci 311 (May 2019): 31–38. https://doi.org/10.1016/j.mbs.2018.12.017.Full Text Link to Item
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Nazarian, Alireza, Konstantin G. Arbeev, Arseniy P. Yashkin, and Alexander M. Kulminski. “Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.” Geroscience 41, no. 2 (April 2019): 137–54. https://doi.org/10.1007/s11357-019-00071-5.Full Text
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Olivia Bagley, Ilya Y. Zhbannikov, Alan A. Cohen, Alexander M. Kulminski, and Anatoliy I. Yashin. “"Physiological Dysregulation" as a Promising Measure of Robustness and Resilience in Studies of Aging and a New Indicator of Preclinical Disease.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 74, no. 4 (March 2019): 462–68. https://doi.org/10.1093/gerona/gly136.Full Text
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Kulminski, Alexander M., Yury Loika, Irina Culminskaya, Jian Huang, Konstantin G. Arbeev, Olivia Bagley, Mary F. Feitosa, et al. “Independent associations of TOMM40 and APOE variants with body mass index.” Aging Cell 18, no. 1 (February 2019): e12869. https://doi.org/10.1111/acel.12869.Full Text
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Kulminski, Alexander M., Yury Loika, Jian Huang, Konstantin G. Arbeev, Olivia Bagley, Svetlana Ukraintseva, Anatoliy I. Yashin, and Irina Culminskaya. “Pleiotropic Meta-Analysis of Age-Related Phenotypes Addressing Evolutionary Uncertainty in Their Molecular Mechanisms.” Frontiers in Genetics 10 (January 2019): 433. https://doi.org/10.3389/fgene.2019.00433.Full Text
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Yashin, Anatoliy I., Konstantin G. Arbeev, Deqing Wu, Liubov S. Arbeeva, Olivia Bagley, Eric Stallard, Alexander M. Kulminski, et al. “Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 73, no. 11 (October 2018): 1472–81. https://doi.org/10.1093/gerona/gly057.Full Text
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He, Liang, Irina Culminskaya, Yury Loika, Konstantin G. Arbeev, Olivia Bagley, Matt Duan, Anatoliy I. Yashin, and Alexander M. Kulminski. “Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study.” Experimental Gerontology 107 (July 2018): 74–86. https://doi.org/10.1016/j.exger.2017.09.019.Full Text
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Yashin, Anatoliy I., Fang Fang, Mikhail Kovtun, Deqing Wu, Matt Duan, Konstantin Arbeev, Igor Akushevich, et al. “Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.” Experimental Gerontology 107 (July 2018): 148–60. https://doi.org/10.1016/j.exger.2017.10.020.Full Text
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Akushevich, Igor, Arseniy P. Yashkin, Julia Kravchenko, Fang Fang, Konstantin Arbeev, Frank Sloan, and Anatoliy I. Yashin. “Identifying the causes of the changes in the prevalence patterns of diabetes in older U.S. adults: A new trend partitioning approach.” J Diabetes Complications 32, no. 4 (April 2018): 362–67. https://doi.org/10.1016/j.jdiacomp.2017.12.014.Full Text Link to Item
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Kulminski, Alexander M., Jian Huang, Yury Loika, Konstantin G. Arbeev, Olivia Bagley, Arseniy Yashkin, Matt Duan, and Irina Culminskaya. “Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.” Aging 10, no. 3 (March 2018): 492–514. https://doi.org/10.18632/aging.101407.Full Text
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Arbeeva, Liubov S., Heidi A. Hanson, Konstantin G. Arbeev, Alexander M. Kulminski, Eric Stallard, Svetlana V. Ukraintseva, Deqing Wu, et al. “How Well Does the Family Longevity Selection Score Work: A Validation Test Using the Utah Population Database.” Frontiers in Public Health 6 (January 2018): 277. https://doi.org/10.3389/fpubh.2018.00277.Full Text
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Kulminski, Alexander M., Amisha V. Barochia, Yury Loika, Nalini Raghavachari, Konstantin G. Arbeev, Mary K. Wojczynski, Bharat Thyagarajan, et al. “The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study.” Plos One 13, no. 11 (January 2018): e0206873. https://doi.org/10.1371/journal.pone.0206873.Full Text
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He, Liang, Ilya Zhbannikov, Konstantin G. Arbeev, Anatoliy I. Yashin, and Alexander M. Kulminski. “A genetic stochastic process model for genome-wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data.” Genetic Epidemiology 41, no. 7 (November 2017): 620–35. https://doi.org/10.1002/gepi.22058.Full Text
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Zhbannikov, Ilya Y., Konstantin G. Arbeev, and Anatoliy I. Yashin. “rqt: an R package for gene-level meta-analysis.” Bioinformatics (Oxford, England) 33, no. 19 (October 2017): 3129–30. https://doi.org/10.1093/bioinformatics/btx395.Full Text
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Steenstrup, Troels, Jeremy D. Kark, Simon Verhulst, Mikael Thinggaard, Jacob V. B. Hjelmborg, Christine Dalgård, Kirsten Ohm Kyvik, et al. “Telomeres and the natural lifespan limit in humans.” Aging 9, no. 4 (April 2017): 1130–42. https://doi.org/10.18632/aging.101216.Full Text Open Access Copy
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Akushevich, I., A. P. Yashkin, J. Kravchenko, F. Fang, K. Arbeev, F. Sloan, and A. I. Yashin. “Theory of partitioning of disease prevalence and mortality in observational data.” Theor Popul Biol 114 (April 2017): 117–27. https://doi.org/10.1016/j.tpb.2017.01.003.Full Text Open Access Copy Link to Item
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Kulminski, Alexander M., Yelena Kernogitski, Irina Culminskaya, Yury Loika, Konstantin G. Arbeev, Olivia Bagley, Matt Duan, et al. “Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits.” Aging Cell 16, no. 1 (February 2017): 61–72. https://doi.org/10.1111/acel.12526.Full Text Open Access Copy
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Zhbannikov, Ilya Y., Konstantin Arbeev, Igor Akushevich, Eric Stallard, and Anatoliy I. Yashin. “stpm: an R package for stochastic process model.” Bmc Bioinformatics 18, no. 1 (February 2017): 125. https://doi.org/10.1186/s12859-017-1538-7.Full Text Open Access Copy
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Zhbannikov, Ilya Y., Konstantin Arbeev, Svetlana Ukraintseva, and Anatoliy I. Yashin. “haploR: an R package for querying web-based annotation tools.” F1000research 6 (January 2017): 97. https://doi.org/10.12688/f1000research.10742.2.Full Text
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Zhbannikov, Ilya Y., Konstantin G. Arbeev, and Anatoliy I. Yashin. “cophesim: a comprehensive phenotype simulator for testing novel association methods.” F1000research 6 (January 2017): 1294. https://doi.org/10.12688/f1000research.11968.1.Full Text
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He, Liang, Yelena Kernogitski, Irina Kulminskaya, Yury Loika, Konstantin G. Arbeev, Elena Loiko, Olivia Bagley, et al. “Corrigendum: Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.” Frontiers in Genetics 8 (January 2017): 226. https://doi.org/10.3389/fgene.2017.00226.Full Text
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Kulminski, Alexander M., Nalini Raghavachari, Konstantin G. Arbeev, Irina Culminskaya, Liubov Arbeeva, Deqing Wu, Svetlana V. Ukraintseva, Kaare Christensen, and Anatoliy I. Yashin. “Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study.” Biogerontology 17, no. 5–6 (November 2016): 893–905. https://doi.org/10.1007/s10522-016-9659-3.Full Text Open Access Copy
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Ukraintseva, Svetlana, Anatoliy I. Yashin, and Konstantin G. Arbeev. “Resilience Versus Robustness in Aging.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 71, no. 11 (November 2016): 1533–34. https://doi.org/10.1093/gerona/glw083.Full Text Open Access Copy
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Kulminski, Alexander M., Liang He, Irina Culminskaya, Yury Loika, Yelena Kernogitski, Konstantin G. Arbeev, Elena Loiko, et al. “Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality.” Plos Genetics 12, no. 11 (November 2016): e1006314. https://doi.org/10.1371/journal.pgen.1006314.Full Text
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Zhbannikov, I., K. Arbeev, and A. Yashin. “Multidimensional Stochastic Process Model and its applications to analysis of longitudinal data with genetic information.” Acm Bcb 2016 7th Acm Conference on Bioinformatics, Computational Biology, and Health Informatics, October 2, 2016, 467–68. https://doi.org/10.1145/2975167.2985634.Full Text Open Access Copy
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Kulminski, Alexander M., Yury Loika, Irina Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Eric Stallard, and Anatoliy I. Yashin. “Explicating heterogeneity of complex traits has strong potential for improving GWAS efficiency.” Scientific Reports 6 (October 2016): 35390. https://doi.org/10.1038/srep35390.Full Text Open Access Copy
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “Dynamics of biomarkers in relation to aging and mortality.” Mechanisms of Ageing and Development 156 (June 2016): 42–54. https://doi.org/10.1016/j.mad.2016.04.010.Full Text Open Access Copy
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Ukraintseva, Svetlana, Anatoliy Yashin, Konstantin Arbeev, Alexander Kulminski, Igor Akushevich, Deqing Wu, Gaurang Joshi, Kenneth C. Land, and Eric Stallard. “Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants.” Biogerontology 17, no. 1 (February 2016): 109–27. https://doi.org/10.1007/s10522-015-9600-1.Full Text Open Access Copy
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Yashin, Anatoliy I., Konstantin G. Arbeev, Liubov S. Arbeeva, Deqing Wu, Igor Akushevich, Mikhail Kovtun, Arseniy Yashkin, et al. “How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity.” Biogerontology 17, no. 1 (February 2016): 89–107. https://doi.org/10.1007/s10522-015-9594-8.Full Text Open Access Copy
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Yashin, Anatoliy I., Konstantin G. Arbeev, Deqing Wu, Liubov Arbeeva, Alexander Kulminski, Irina Kulminskaya, Igor Akushevich, and Svetlana V. Ukraintseva. “How Genes Modulate Patterns of Aging-Related Changes on the Way to 100: Biodemographic Models and Methods in Genetic Analyses of Longitudinal Data.” North American Actuarial Journal : Naaj 20, no. 3 (January 2016): 201–32. https://doi.org/10.1080/10920277.2016.1178588.Full Text Open Access Copy
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He, Liang, Yelena Kernogitski, Irina Kulminskaya, Yury Loika, Konstantin G. Arbeev, Elena Loiko, Olivia Bagley, et al. “Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.” Frontiers in Genetics 7 (January 2016): 179. https://doi.org/10.3389/fgene.2016.00179.Full Text Open Access Copy
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Yashin, Anatoliy I., Ilya Zhbannikov, Liubov Arbeeva, Konstantin G. Arbeev, Deqing Wu, Igor Akushevich, Arseniy Yashkin, et al. “Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures.” Frontiers in Genetics 7 (January 2016): 188. https://doi.org/10.3389/fgene.2016.00188.Full Text Open Access Copy
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“IMPACTS OF CEREBROVASCULAR AND NEURODEGENERATIVE DISEASES ON SURVIVAL OF LUNG CANCER PATIENTS.” The Gerontologist 55, no. Suppl_2 (November 2015): 496–496. https://doi.org/10.1093/geront/gnv214.03.Full Text Open Access Copy
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Kulminski, Alexander M., Konstantin G. Arbeev, Irina Culminskaya, Svetlana V. Ukraintseva, Eric Stallard, Michael A. Province, and Anatoli I. Yashin. “Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: insights on mechanisms from the Long Life Family Study.” Rejuvenation Research 18, no. 2 (April 2015): 128–35. https://doi.org/10.1089/rej.2014.1616.Full Text Open Access Copy
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Kravchenko, Julia, Mark Berry, Konstantin Arbeev, H Kim Lyerly, Anatoly Yashin, and Igor Akushevich. “Cardiovascular comorbidities and survival of lung cancer patients: Medicare data based analysis.” Lung Cancer 88, no. 1 (April 2015): 85–93. https://doi.org/10.1016/j.lungcan.2015.01.006.Full Text Open Access Copy Link to Item
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Kulminski, Alexander M., Irina Culminskaya, Konstantin G. Arbeev, Liubov Arbeeva, Svetlana V. Ukraintseva, Eric Stallard, Deqing Wu, and Anatoliy I. Yashin. “Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies.” Plos One 10, no. 8 (January 2015): e0136319. https://doi.org/10.1371/journal.pone.0136319.Full Text Open Access Copy
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Yashin, Anatoliy I., Deqing Wu, Liubov S. Arbeeva, Konstantin G. Arbeev, Alexander M. Kulminski, Igor Akushevich, Mikhail Kovtun, et al. “Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.” Frontiers in Genetics 6 (January 2015): 122. https://doi.org/10.3389/fgene.2015.00122.Full Text Open Access Copy
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Akushevich, Igor, Konstantin Arbeev, Julia Kravchenko, and Mark Berry. “Causal effects of time-dependent treatments in older patients with non-small cell lung cancer.” Plos One 10, no. 4 (2015): e0121406. https://doi.org/10.1371/journal.pone.0121406.Full Text Open Access Copy Link to Item
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Kravchenko, J., M. F. Berry, K. G. Arbeev, and I. Akushevich. “CARDIOVASCULAR COMORBIDITIES IN LUNG CANCER PATIENTS: TREATMENT-SPECIFIC EFFECTS ON SURVIVAL.” Gerontologist 54 (November 1, 2014): 122–122.Open Access Copy Link to Item
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Arbeev, Konstantin G., Igor Akushevich, Alexander M. Kulminski, Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “Joint Analyses of Longitudinal and Time-to-Event Data in Research on Aging: Implications for Predicting Health and Survival.” Frontiers in Public Health 2 (January 2014): 228. https://doi.org/10.3389/fpubh.2014.00228.Full Text Open Access Copy
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Kulminski, A. M., K. G. Arbeev, I. Culminskaya, L. Arbeeva, S. V. Ukraintseva, E. Stallard, K. Christensen, N. Schupf, M. A. Province, and A. I. Yashin. “Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan.” Plos Genetics 10, no. 1 (January 1, 2014). https://doi.org/10.1371/journal.pgen.1004141.Full Text
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Arbeev, Konstantin G., Igor Akushevich, Alexander M. Kulminski, Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “Biodemographic Analyses of Longitudinal Data on Aging, Health, and Longevity: Recent Advances and Future Perspectives.” Advances in Geriatrics 2014 (January 2014): 957073. https://doi.org/10.1155/2014/957073.Full Text Open Access Copy
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Kulminski, Alexander M., Konstantin G. Arbeev, Irina Culminskaya, Liubov Arbeeva, Svetlana V. Ukraintseva, Eric Stallard, Kaare Christensen, Nicole Schupf, Michael A. Province, and Anatoli I. Yashin. “Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan.” Plos Genetics 10, no. 1 (January 2014): e1004141. https://doi.org/10.1371/journal.pgen.1004141.Full Text Open Access Copy
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Yashin, Anatoliy I., Deqing Wu, Konstantin G. Arbeev, Liubov S. Arbeeva, Igor Akushevich, Alexander Kulminski, Irina Culminskaya, Eric Stallard, and Svetlana V. Ukraintseva. “Genetic Structures of Population Cohorts Change with Increasing Age: Implications for Genetic Analyses of Human aging and Life Span.” Annals of Gerontology and Geriatric Research 1, no. 4 (January 2014): 1020.Open Access Copy
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Akushevich, Igor, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, Alexander Kulminski, and Anatoliy I. Yashin. “Morbidity risks among older adults with pre-existing age-related diseases.” Exp Gerontol 48, no. 12 (December 2013): 1395–1401. https://doi.org/10.1016/j.exger.2013.09.005.Full Text Open Access Copy Link to Item
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Arbeev, K. G., A. A. Cohen, L. Arbeeva, E. Milot, I. Akushevich, A. Kulminski, and A. I. Yashin. “MATHEMATICAL MODELS OF PHYSIOLOGICAL DYSREGULATION TRAJECTORIES DURING AGING.” Gerontologist 53 (November 1, 2013): 222–222.Link to Item
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Kulminski, A., I. Culminskaya, K. G. Arbeev, L. Arbeeva, S. V. Ukraintseva, and A. I. Yashin. “THE ROLE OF THE APOLIPOPROTEIN E4 ALLELE, CANCER, CVD AND NEURODEGENERATIVE DISORDERS IN HUMAN LIFESPAN.” Gerontologist 53 (November 1, 2013): 250–250.Open Access Copy Link to Item
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Akushevich, Igor, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoliy I. Yashin. “Recovery and survival from aging-associated diseases.” Exp Gerontol 48, no. 8 (August 2013): 824–30. https://doi.org/10.1016/j.exger.2013.05.056.Full Text Open Access Copy Link to Item
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Kulminski, Alexander M., Konstantin G. Arbeev, Kaare Christensen, Eric Stallard, Iva Miljkovic, Michael Barmada, and Anatoliy I. Yashin. “Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children.” J Gerontol a Biol Sci Med Sci 68, no. 7 (July 2013): 760–68. https://doi.org/10.1093/gerona/gls243.Full Text Open Access Copy Link to Item
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Akushevich, Igor, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoli I. Yashin. “Circulatory Diseases in the U.S. Elderly in the Linked National Long-Term Care Survey-Medicare Database: Population-Based Analysis of Incidence, Comorbidity, and Disability.” Res Aging 35, no. 4 (July 2013): 437–58. https://doi.org/10.1177/0164027512446941.Full Text Open Access Copy Link to Item
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Akushevich, Igor, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoly I. Yashin. “Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis.” Age Ageing 42, no. 4 (July 2013): 494–500. https://doi.org/10.1093/ageing/aft032.Full Text Open Access Copy Link to Item
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Kulminski, Alexander M., Irina Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Eric Stallard, Liubov Arbeeva, and Anatoli I. Yashin. “The role of lipid-related genes, aging-related processes, and environment in healthspan.” Aging Cell 12, no. 2 (April 2013): 237–46. https://doi.org/10.1111/acel.12046.Full Text Open Access Copy
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Kulminski, Alexander M., Irina Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Liubov Arbeeva, and Anatoli I. Yashin. “Trade-off in the effect of the APOE gene on the ages at onset of cardiocascular disease and cancer across ages, gender, and human generations.” Rejuvenation Research 16, no. 1 (February 2013): 28–34. https://doi.org/10.1089/rej.2012.1362.Full Text Open Access Copy
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Yashin, Anatoliy I., Deqing Wu, Konstantin G. Arbeev, Alexander M. Kulminski, Eric Stallard, and Svetlana V. Ukraintseva. “Why does melanoma metastasize into the brain? Genes with pleiotropic effects might be the key.” Frontiers in Genetics 4 (January 2013): 75. https://doi.org/10.3389/fgene.2013.00075.Full Text Open Access Copy
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Yashin, Anatoliy I., Konstantin G. Arbeev, Deqing Wu, Liubov S. Arbeeva, Alexander M. Kulminski, Igor Akushevich, Irina Culminskaya, Eric Stallard, and Svetlana V. Ukraintseva. “How the quality of GWAS of human lifespan and health span can be improved.” Frontiers in Genetics 4 (January 2013): 125. https://doi.org/10.3389/fgene.2013.00125.Full Text Open Access Copy
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Yashin, Anatoliy I., Konstantin G. Arbeev, Deqing Wu, Liubov S. Arbeeva, Alexander Kulminski, Igor Akushevich, Irina Culminskaya, Eric Stallard, and Svetlana V. Ukraintseva. “How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data.” Frontiers in Genetics 4 (January 2013): 3. https://doi.org/10.3389/fgene.2013.00003.Full Text Open Access Copy
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Yashin, A. I., K. G. Arbeev, S. V. Ukraintseva, I. Akushevich, and A. Kulminski. “Patterns of Aging-Related changes on the way to 100: An Approach to studying aging, mortality, and longevity from longitudinal data.” North American Actuarial Journal 16, no. 4 (December 1, 2012): 403–33. https://doi.org/10.1080/10920277.2012.10597640.Full Text Open Access Copy
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Akushevich, I., J. Kravchenko, H. Whitson, H. J. Cohen, S. V. Ukraintseva, K. G. Arbeev, and A. I. Yashin. “MEDICARE-BASED MULTIMORBIDITY INDEX FOR PROJECTING MORBIDITY AND MORTALITY AMONG OLDER ADULTS IN THE U.S.” Gerontologist 52 (November 1, 2012): 630–630.Open Access Copy Link to Item
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Akushevich, I., J. Kravchenko, S. V. Ukraintseva, K. G. Arbeev, and A. I. Yashin. “MUTUAL DEPENDENCE OF RISKS OF CANCER AND CHRONIC NON-CANCER DISEASES: MEDICARE-BASED ANALYSIS.” Gerontologist 52 (November 1, 2012): 372–372.Link to Item
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Arbeev, K. G., I. Akushevich, A. Kulminski, S. V. Ukraintseva, L. Arbeeva, I. Culminskaya, D. Wu, and A. I. Yashin. “EVALUATING EFFECTS OF GENES AND AGE TRAJECTORIES OF PHYSIOLOGICAL VARIABLES ON MORTALITY AND MORBIDITY RISKS: APPLICATION OF GENETIC STOCHASTIC PROCESS MODEL.” Gerontologist 52 (November 1, 2012): 152–152.Link to Item
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Kulminski, A., I. Culminskaya, K. G. Arbeev, S. V. Ukraintseva, L. Arbeeva, and A. I. Yashin. “TRADE-OFF IN THE EFFECT OF THE APOLIPOPROTEIN E POLYMORPHISM ON THE AGES AT ONSET OF CVD AND CANCER: THE ROLE OF AGE AND GENDER ACROSS GENERATIONS.” Gerontologist 52 (November 1, 2012): 153–153.Open Access Copy Link to Item
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Kulminski, A., I. Culminskaya, K. G. Arbeev, S. V. Ukraintseva, L. Arbeeva, and A. I. Yashin. “GENES, HEALTH, AGING, AND ENVIRONMENT: HOW ARE THEY RELATED?” Gerontologist 52 (November 1, 2012): 123–123.Link to Item
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Yashin, A. I., D. Wu, K. G. Arbeev, I. Akushevich, A. Kulminski, P. Stallard, L. Arbeeva, and S. V. Ukraintseva. “GENETIC AND NON-GENETIC FACTORS IN AGING, HEALTH, AND LIFESPAN: INSIGHTS FROM BIODEMOGRAPHIC ANALYSES.” Gerontologist 52 (November 1, 2012): 123–123.Link to Item
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Yashin, A. I., K. G. Arbeev, I. Akushevich, A. Kulminski, P. Stallard, D. Wu, L. Arbeeva, and S. V. Ukraintseva. “CONNECTION BETWEEN INDIVIDUAL AGING AND MORTALITY: THE RESULTS OF BIO-DEMOGRAPHIC ANALYSES.” Gerontologist 52 (November 1, 2012): 261–261.Link to Item
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Yashin, Anatoliy I., Deqing Wu, Konstantin G. Arbeev, Eric Stallard, Kenneth C. Land, and Svetlana V. Ukraintseva. “How genes influence life span: the biodemography of human survival.” Rejuvenation Research 15, no. 4 (August 2012): 374–80. https://doi.org/10.1089/rej.2011.1290.Full Text Open Access Copy
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Yashin, Anatoliy I., Deqing Wu, Konstantin G. Arbeev, and Svetlana V. Ukraintseva. “Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality.” Rejuvenation Research 15, no. 4 (August 2012): 381–94. https://doi.org/10.1089/rej.2011.1257.Full Text Open Access Copy
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Yashin, A. I., K. G. Arbeev, I. Akushevich, A. Kulminski, S. V. Ukraintseva, E. Stallard, and K. C. Land. “Modeling longitudinal data on health aging and life span.” Physics of Life Reviews 9, no. 2 (June 1, 2012): 195–97. https://doi.org/10.1016/j.plrev.2012.05.018.Full Text Open Access Copy
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Yashin, A. I., K. G. Arbeev, I. Akushevich, A. Kulminski, S. V. Ukraintseva, E. Stallard, and K. C. Land. “The quadratic hazard model for analyzing longitudinal data on aging, health, and the life span.” Physics of Life Reviews 9, no. 2 (June 2012): 177–88. https://doi.org/10.1016/j.plrev.2012.05.002.Full Text Open Access Copy
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Akushevich, Igor, Galina Veremeyeva, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, Alexander V. Akleyev, and Anatoly I. Yashin. “New stochastic carcinogenesis model with covariates: an approach involving intracellular barrier mechanisms.” Math Biosci 236, no. 1 (March 2012): 16–30. https://doi.org/10.1016/j.mbs.2011.12.002.Full Text Open Access Copy Link to Item
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Akushevich, Igor, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoliy I. Yashin. “Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis.” J Am Geriatr Soc 60, no. 2 (February 2012): 323–27. https://doi.org/10.1111/j.1532-5415.2011.03786.x.Full Text Open Access Copy Link to Item
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Alexander M. Kulminski, Igor Akushevich, Liubov S. Arbeeva, Irina V. Culminskaya, Deqing Wu, and Anatoliy I. Yashin. “Effect of the APOE Polymorphism and Age Trajectories of Physiological Variables on Mortality: Application of Genetic Stochastic Process Model of Aging.” Scientifica 2012 (January 2012): 568628. https://doi.org/10.6064/2012/568628.Full Text Open Access Copy
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Yashin, A. I., I. Akushevich, K. G. Arbeev, A. Kulminski, and S. Ukraintseva. “Joint analysis of health histories, physiological state, and survival.” Mathematical Population Studies 18, no. 4 (December 1, 2011): 207–33. https://doi.org/10.1080/08898480.2011.614486.Full Text Open Access Copy
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Akushevich, I., J. Kravchenko, S. V. Ukraintseva, K. G. Arbeev, and A. I. Yashin. “PATTERNS OF AGING-RELATED DISEASES INCIDENCE AND RECOVERY IN US ELDERLY.” Gerontologist 51 (November 1, 2011): 229–229.Open Access Copy Link to Item
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Akushevich, I., J. Kravchenko, S. V. Ukraintseva, K. G. Arbeev, and A. I. Yashin. “LIFESTYLE EFFECTS ON MORBIDITY AND MORTALITY IN US ELDERLY POPULATION.” Gerontologist 51 (November 1, 2011): 333–333.Link to Item
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Kulminski, A., K. G. Arbeev, K. Christensen, A. B. Newman, M. A. Province, I. T. Elo, R. Mayeux, and A. I. Yashin. “DO EARLY-LIFE AGING-RELATED PHENOTYPES IN ADULTS PREDICT HEALTH TRAITS AT LATE AGES IN FAMILIES? INSIGHTS FROM THE LONG-LIFE FAMILY STUDY.” Gerontologist 51 (November 1, 2011): 122–122.Link to Item
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Yashin, A. I., D. Wu, K. G. Arbeev, and S. V. Ukraintseva. “HOW GENES CONTRIBUTE TO AGING RELATED CHANGES AND AFFECT LIFE SPAN IN HUMANS.” Gerontologist 51 (November 1, 2011): 121–121.Link to Item
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Kulminski, Alexander M., Irina Culminskaya, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Liubov Arbeeva, Deqing Wu, Igor Akushevich, Kenneth C. Land, and Anatoli I. Yashin. “Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan.” Aging Cell 10, no. 3 (June 2011): 533–41. https://doi.org/10.1111/j.1474-9726.2011.00689.x.Full Text Open Access Copy
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Akushevich, Igor V., Galina A. Veremeyeva, Georgy P. Dimov, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Alexander V. Akleyev, and Anatoly I. Yashin. “Modeling hematopoietic system response caused by chronic exposure to ionizing radiation.” Radiation and Environmental Biophysics 50, no. 2 (May 2011): 299–311. https://doi.org/10.1007/s00411-011-0351-3.Full Text Open Access Copy
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Arbeev, Konstantin G., Steven C. Hunt, Masayuki Kimura, Abraham Aviv, and Anatoliy I. Yashin. “Leukocyte telomere length, breast cancer risk in the offspring: the relations with father's age at birth.” Mechanisms of Ageing and Development 132, no. 4 (April 2011): 149–53. https://doi.org/10.1016/j.mad.2011.02.004.Full Text Open Access Copy
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Liubov S. Arbeeva, Igor Akushevich, Alexander M. Kulminski, and Anatoliy I. Yashin. “Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data.” Biogerontology 12, no. 2 (April 2011): 157–66. https://doi.org/10.1007/s10522-010-9316-1.Full Text Open Access Copy
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Kulminski, Alexander M., Konstantin G. Arbeev, Kaare Christensen, Richard Mayeux, Anne B. Newman, Michael A. Province, Evan C. Hadley, et al. “Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits.” Mechanisms of Ageing and Development 132, no. 4 (April 2011): 195–201. https://doi.org/10.1016/j.mad.2011.03.006.Full Text Open Access Copy
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Igor Akushevich, Alexander M. Kulminski, Liubov S. Arbeeva, Lucy Akushevich, Irina V. Culminskaya, and Anatoliy I. Yashin. “Age trajectories of physiological indices in relation to healthy life course.” Mechanisms of Ageing and Development 132, no. 3 (March 2011): 93–102. https://doi.org/10.1016/j.mad.2011.01.001.Full Text Open Access Copy
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Akushevich, Igor, Julia Kravchenko, Lucy Akushevich, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoliy I. Yashin. “Medical cost trajectories and onsets of cancer and noncancer diseases in US elderly population.” Comput Math Methods Med 2011 (2011): 857892. https://doi.org/10.1155/2011/857892.Full Text Open Access Copy Link to Item
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Akushevich, Igor, Julia Kravchenko, Lucy Akushevich, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoliy Yashin. “Cancer Risk and Behavioral Factors, Comorbidities, and Functional Status in the US Elderly Population.” Isrn Oncology 2011 (January 2011): 415790. https://doi.org/10.5402/2011/415790.Full Text Open Access Copy
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Matteini, Amy M., M Daniele Fallin, Candace M. Kammerer, Nicole Schupf, Anatoli I. Yashin, Kaare Christensen, Konstantin G. Arbeev, et al. “Heritability estimates of endophenotypes of long and health life: the Long Life Family Study.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 65, no. 12 (December 2010): 1375–79. https://doi.org/10.1093/gerona/glq154.Full Text Open Access Copy
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Kulminski, A., I. Culminskaya, S. V. Ukraintseva, K. G. Arbeev, and A. I. Yashin. “SYSTEMIC GENETIC DETERMINANTS OF HEALTHY AGING AND EVOLUTIONARY SELECTION IN HUMANS.” Gerontologist 50 (October 1, 2010): 266–266.Link to Item
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Yashin, A. I., K. G. Arbeev, S. V. Ukraintseva, I. Akushevich, A. Kulminski, J. Kravchenko, D. Il’yasova, and D. Wu. “NEW PREDICTORS OF EXCEPTIONAL HEALTH AND SURVIVAL FROM LONGITUDINAL DATA.” Gerontologist 50 (October 1, 2010): 20–20.Link to Item
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Akushevich, Igor V., Galina A. Veremeyeva, Georgy P. Dimov, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Alexander V. Akleyev, and Anatoly I. Yashin. “Modeling deterministic effects in hematopoietic system caused by chronic exposure to ionizing radiation in large human cohorts.” Health Physics 99, no. 3 (September 2010): 322–29. https://doi.org/10.1097/hp.0b013e3181c61dc1.Full Text Open Access Copy
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Yashin, Anatoliy I., Deqing Wu, Konstantin G. Arbeev, and Svetlana V. Ukraintseva. “Joint influence of small-effect genetic variants on human longevity.” Aging 2, no. 9 (September 2010): 612–20. https://doi.org/10.18632/aging.100191.Full Text Open Access Copy
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Ukraintseva, Svetlana V., Konstantin G. Arbeev, Igor Akushevich, Alexander Kulminski, Liubov Arbeeva, Irina Culminskaya, Lucy Akushevich, and Anatoli I. Yashin. “Trade-offs between cancer and other diseases: do they exist and influence longevity?” Rejuvenation Research 13, no. 4 (August 2010): 387–96. https://doi.org/10.1089/rej.2009.0941.Full Text Open Access Copy
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Risques, Rosa Ana, Konstantin G. Arbeev, Anatoli I. Yashin, Svetlana V. Ukraintseva, George M. Martin, Peter S. Rabinovitch, and Junko Oshima. “Leukocyte telomere length is associated with disability in older u.s. Population.” Journal of the American Geriatrics Society 58, no. 7 (July 2010): 1289–98. https://doi.org/10.1111/j.1532-5415.2010.02948.x.Full Text Open Access Copy
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Yashin, Anatoli I., Konstantin G. Arbeev, Igor Akushevich, Svetlana V. Ukraintseva, Alexander Kulminski, Liubov S. Arbeeva, and Irina Culminskaya. “Exceptional survivors have lower age trajectories of blood glucose: lessons from longitudinal data.” Biogerontology 11, no. 3 (June 2010): 257–65. https://doi.org/10.1007/s10522-009-9243-1.Full Text
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Kulminski, Alexander M., Irina Culminskaya, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Kenneth C. Land, and Anatoli I. Yashin. “Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context.” Mechanisms of Ageing and Development 131, no. 5 (May 2010): 338–45. https://doi.org/10.1016/j.mad.2010.04.001.Full Text Open Access Copy
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Yashin, Anatoli I., Konstantin G. Arbeev, Alexander Kulminski, Ingrid Borecki, Kaare Christensen, Michael Barmada, Evan Hadley, et al. “"Predicting" parental longevity from offspring endophenotypes: data from the Long Life Family Study (LLFS).” Mechanisms of Ageing and Development 131, no. 3 (March 2010): 215–22. https://doi.org/10.1016/j.mad.2010.02.001.Full Text
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Yashin, Anatoli, Igor Akushevich, Svetlana Ukraintseva, Lucy Akushevich, Konstantin Arbeev, and Alexander Kulminski. “Trends in survival and recovery from stroke: evidence from the National Long-Term Care Survey/Medicare data.” Stroke 41, no. 3 (March 2010): 563–65. https://doi.org/10.1161/strokeaha.109.572339.Full Text
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Kulminski, Alexander M., Irina V. Culminskaya, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Igor Akushevich, Kenneth C. Land, and Anatoli I. Yashin. “Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction.” Rejuvenation Research 13, no. 1 (February 2010): 13–21. https://doi.org/10.1089/rej.2009.0905.Full Text Open Access Copy
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Yashin, Anatoli I., Konstantin G. Arbeev, Igor Akushevich, Liubov Arbeeva, Julia Kravchenko, Dora Il’yasova, Alexander Kulminski, et al. “Dynamic determinants of longevity and exceptional health.” Curr Gerontol Geriatr Res 2010 (2010). https://doi.org/10.1155/2010/381637.Full Text Link to Item
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Kulminski, Alexander M., Freerk Molleman, Irina V. Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, James R. Carey, and Anatoli I. Yashin. “Date of eclosion modulates longevity: insights across dietary-restriction gradients and female reproduction in the mexfly Anastrepha ludens.” Experimental Gerontology 44, no. 11 (November 2009): 718–26. https://doi.org/10.1016/j.exger.2009.08.007.Full Text
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Kulminski, A., F. Molleman, I. Culminskaya, K. Arbeev, S. Ukraintseva, J. Carey, and A. I. Yashin. “DATE OF ECLOSION AS A DETERMINANT OF LONG LIFE IN THE MEXFLY ANASTREPHA LUDENS: INSIGHTS ACROSS DIET, CALORIC RESTRICTION AND REPRODUCTION.” Gerontologist 49 (October 1, 2009): 141–141.Link to Item
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Kulminski, A., I. Culminskaya, S. V. Ukraintseva, K. G. Arbeev, K. Land, and A. I. Yashin. “SYSTEMIC BIOLOGICAL ROLE OF THE BETA2-ADRENERGIC RECEPTOR GENE POLYMORPHISMS IN HEALTHY AGING.” Gerontologist 49 (October 1, 2009): 90–90.Link to Item
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Yashin, A. I., K. G. Arbeev, I. Akushevich, S. V. Ukraintseva, A. Kulminski, L. Arbeeva, and I. Culminskaya. “DYNAMIC DETERMINANTS OF EXCEPTIONAL HEALTH AND LONGEVITY.” Gerontologist 49 (October 1, 2009): 183–183.Link to Item
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Yashin, A. I., K. G. Arbeev, I. Akushevich, S. V. Ukraintseva, A. Kulminski, L. Arbeeva, and I. Culminskaya. “PHYSIOLOGICAL CHANGES DURING THE LIFE COURSE: INSIGHTS FOR AGING, HEALTH, AND LONGEVITY.” Gerontologist 49 (October 1, 2009): 90–90.Link to Item
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Yashin, Anatoli I., Svetlana V. Ukraintseva, Konstantin G. Arbeev, Igor Akushevich, Liubov S. Arbeeva, and Alexander M. Kulminski. “Maintaining physiological state for exceptional survival: What is the normal level of blood glucose and does it change with age?” Mechanisms of Ageing and Development 130, no. 9 (September 2009): 611–18. https://doi.org/10.1016/j.mad.2009.07.004.Full Text
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Arbeev, Konstantin G., Igor Akushevich, Alexander M. Kulminski, Liubov S. Arbeeva, Lucy Akushevich, Svetlana V. Ukraintseva, Irina V. Culminskaya, and Anatoli I. Yashin. “Genetic model for longitudinal studies of aging, health, and longevity and its potential application to incomplete data.” Journal of Theoretical Biology 258, no. 1 (May 2009): 103–11. https://doi.org/10.1016/j.jtbi.2009.01.023.Full Text
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Yashin, Anatoli I., Igor Akushevich, Konstantin Arbeev, Lucy Akushevich, Alexander Kulminski, and Svetlana Ukraintseva. “Studying health histories of cancer: a new model connecting cancer incidence and survival.” Mathematical Biosciences 218, no. 2 (April 2009): 88–97. https://doi.org/10.1016/j.mbs.2008.12.007.Full Text
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Kulminski, Alexander M., Konstantin G. Arbeev, Irina V. Culminskaya, Svetlana V. Ukraintseva, Kaare Christensen, and Anatoli I. Yashin. “Health-related phenotypes and longevity in danish twins.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 64, no. 1 (January 2009): 1–8. https://doi.org/10.1093/gerona/gln051.Full Text
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Yashin, Anatoli I., Svetlana V. Ukraintseva, Igor V. Akushevich, Konstantin G. Arbeev, Alexander Kulminski, and Lucy Akushevich. “Trade-off between cancer and aging: what role do other diseases play? Evidence from experimental and human population studies.” Mechanisms of Ageing and Development 130, no. 1–2 (January 2009): 98–104. https://doi.org/10.1016/j.mad.2008.03.006.Full Text
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Kulminski, Alexander M., Irina V. Culminskaya, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Kenneth C. Land, and Anatoli I. Yashin. “Sex-specific health deterioration and mortality: the morbidity-mortality paradox over age and time.” Experimental Gerontology 43, no. 12 (December 2008): 1052–57. https://doi.org/10.1016/j.exger.2008.09.007.Full Text
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Kulminski, A. M., I. Culminskaya, S. Ukraintseva, K. Arbeev, K. Land, and A. Yashin. “GENDER-SPECIFIC HEALTH DETERIORATION AND MORTALITY: THE MORBIDITY-MORTALITY PARADOX OVER AGE AND TIME.” Gerontologist 48 (October 1, 2008): 544–544.Link to Item
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Kulminski, Alexander M., Svetlana V. Ukraintseva, Irina V. Culminskaya, Konstantin G. Arbeev, Kenneth C. Land, Lucy Akushevich, and Anatoli I. Yashin. “Cumulative deficits and physiological indices as predictors of mortality and long life.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 63, no. 10 (October 2008): 1053–59. https://doi.org/10.1093/gerona/63.10.1053.Full Text
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Ukraintseva, S., I. Culminskaya, K. Arbeev, K. Land, L. Akushevich, and A. Yashin. “CUMULATIVE DEFICIT INDICES BETTER PREDICT MORTALITY AND LONG LIFE THEN PHYSIOLOGICAL RISK FACTORS.” Gerontologist 48 (October 1, 2008): 161–161.Link to Item
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Ukraintseva, S., K. Arbeev, I. Akushevich, I. Culminskaya, and A. Kulminski. “CAPTURING SYSTEMIC ASPECTS OF AGING RELATED CHANGES IN HUMAN: FROM DATA TO MODEL.” Gerontologist 48 (October 1, 2008): 161–161.Link to Item
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Yashin, A., K. Arbeev, A. Kulminski, K. Christensen, I. Borecki, J. Lee, I. Elo, et al. “PREDICTING PARENTAL LONGEVITY FROM OFFSPRING ENDOPHENOTYPES USING DATA FROM THE LONG LIFE FAMILY STUDY.” Gerontologist 48 (October 1, 2008): 492–93.Link to Item
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Kulminski, Alexander M., Konstantin G. Arbeev, Svetlana V. Ukraintseva, Irina V. Culminskaya, Kenneth Land, and Anatoli I. Yashin. “Changes in health status among participants of the Framingham Heart Study from the 1960s to the 1990s: application of an index of cumulative deficits.” Annals of Epidemiology 18, no. 9 (September 2008): 696–701. https://doi.org/10.1016/j.annepidem.2008.06.005.Full Text
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Kulminski, Alexander M., Svetlana V. Ukraintseva, Irina V. Kulminskaya, Konstantin G. Arbeev, Kenneth Land, and Anatoli I. Yashin. “Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study.” Journal of the American Geriatrics Society 56, no. 5 (May 2008): 898–903. https://doi.org/10.1111/j.1532-5415.2008.01656.x.Full Text
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Kulminski, Alexander, Svetlana V. Ukraintseva, Konstantin G. Arbeev, Kenneth G. Manton, Junko Oshima, George M. Martin, and Anatoli I. Yashin. “Association between APOE epsilon 2/epsilon 3/epsilon 4 polymorphism and disability severity in a national long-term care survey sample.” Age and Ageing 37, no. 3 (May 2008): 288–93. https://doi.org/10.1093/ageing/afn003.Full Text
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Yashin, Anatoli I., Konstantin G. Arbeev, Alexander Kulminski, Igor Akushevich, Lucy Akushevich, and Svetlana V. Ukraintseva. “What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data.” Mechanisms of Ageing and Development 129, no. 4 (April 2008): 191–200. https://doi.org/10.1016/j.mad.2007.12.005.Full Text
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Kulminski, Alexander M., Svetlana V. Ukraintseva, Konstantin G. Arbeev, Kenneth G. Manton, Junko Oshima, George M. Martin, Dora Il’yasova, and Anatoli I. Yashin. “Health-protective and adverse effects of the apolipoprotein E epsilon2 allele in older men.” J Am Geriatr Soc 56, no. 3 (March 2008): 478–83. https://doi.org/10.1111/j.1532-5415.2007.01574.x.Full Text Link to Item
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Yashin, Anatoli I., Konstantin G. Arbeev, Igor Akushevich, Alexander Kulminski, Lucy Akushevich, and Svetlana V. Ukraintseva. “Model of hidden heterogeneity in longitudinal data.” Theoretical Population Biology 73, no. 1 (February 2008): 1–10. https://doi.org/10.1016/j.tpb.2007.09.001.Full Text
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Kulminski, Alexander M., Konstantin G. Arbeev, Irina V. Kulminskaya, Svetlana V. Ukraintseva, Kenneth Land, Igor Akushevich, and Anatoli I. Yashin. “Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals.” Journal of the American Geriatrics Society 56, no. 1 (January 2008): 105–10. https://doi.org/10.1111/j.1532-5415.2007.01494.x.Full Text
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Ukraintseva, Svetlana V., Konstantin G. Arbeev, and Anatoli I. Yashin. “Epidemiology of hormone-associated cancers as a reflection of age.” Advances in Experimental Medicine and Biology 630 (January 2008): 57–71. https://doi.org/10.1007/978-0-387-78818-0_5.Full Text
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Kulminski, Alexander, Svetlana V. Ukraintseva, Igor Akushevich, Konstantin G. Arbeev, Kenneth Land, and Anatoli I. Yashin. “Accelerated accumulation of health deficits as a characteristic of aging.” Experimental Gerontology 42, no. 10 (October 2007): 963–70. https://doi.org/10.1016/j.exger.2007.05.009.Full Text
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Yashin, Anatoli I., Konstantin G. Arbeev, Igor Akushevich, Aliaksandr Kulminski, Lucy Akushevich, and Svetlana V. Ukraintseva. “Stochastic model for analysis of longitudinal data on aging and mortality.” Mathematical Biosciences 208, no. 2 (August 2007): 538–51. https://doi.org/10.1016/j.mbs.2006.11.006.Full Text
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Kulminski, Alexander M., Svetlana V. Ukraintseva, Igor V. Akushevich, Konstantin G. Arbeev, and Anatoli I. Yashin. “Cumulative index of health deficiencies as a characteristic of long life.” Journal of the American Geriatrics Society 55, no. 6 (June 2007): 935–40. https://doi.org/10.1111/j.1532-5415.2007.01155.x.Full Text
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Yashin, Anatoli I., Konstantin G. Arbeev, Aliaksandr Kulminski, Igor Akushevich, Lucy Akushevich, and Svetlana V. Ukraintseva. “Health decline, aging and mortality: how are they related?” Biogerontology 8, no. 3 (June 2007): 291–302. https://doi.org/10.1007/s10522-006-9073-3.Full Text
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Yashin, Anatoli I., Konstantin G. Arbeev, and Svetlana V. Ukraintseva. “The accuracy of statistical estimates in genetic studies of aging can be significantly improved.” Biogerontology 8, no. 3 (June 2007): 243–55. https://doi.org/10.1007/s10522-006-9072-4.Full Text
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Kulminski, A., A. Yashin, K. Arbeev, I. Akushevich, S. Ukraintseva, K. Land, and K. Manton. “Cumulative index of health disorders as an indicator of aging-associated processes in the elderly: results from analyses of the National Long Term Care Survey.” Mechanisms of Ageing and Development 128, no. 3 (March 2007): 250–58. https://doi.org/10.1016/j.mad.2006.12.004.Full Text
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Yashin, Anatoli I., Konstantin G. Arbeev, Alexander Kulminski, Igor Akushevich, Lucy Akushevich, and Svetlana V. Ukraintseva. “Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity.” Rejuvenation Research 10, no. 1 (March 2007): 75–86. https://doi.org/10.1089/rej.2006.0500.Full Text
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Yashin, Anatoli I., Igor V. Akushevich, Konstantin G. Arbeev, Lucy Akushevich, Svetlana V. Ukraintseva, and Aliaksandr Kulminski. “Insights on aging and exceptional longevity from longitudinal data: novel findings from the Framingham Heart Study.” Age (Dordrecht, Netherlands) 28, no. 4 (December 2006): 363–74. https://doi.org/10.1007/s11357-006-9023-7.Full Text
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Kulminski, Alexander, Anatoli Yashin, Svetlana Ukraintseva, Igor Akushevich, Konstantin Arbeev, Kenneth Land, and Kenneth Manton. “Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.” Mechanisms of Ageing and Development 127, no. 11 (November 2006): 840–48. https://doi.org/10.1016/j.mad.2006.08.005.Full Text
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Golubovsky, Mikhail D., Nataly Y. Weisman, Konstantin G. Arbeev, Svetlana V. Ukraintseva, and Anatoly I. Yashin. “Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions.” Experimental Gerontology 41, no. 9 (September 2006): 819–27. https://doi.org/10.1016/j.exger.2006.06.035.Full Text
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Ukraintseva, Svetlana, Frank Sloan, Konstantin Arbeev, and Anatoly Yashin. “Increasing rates of dementia at time of declining mortality from stroke.” Stroke 37, no. 5 (May 2006): 1155–59. https://doi.org/10.1161/01.str.0000217971.88034.e9.Full Text
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Weisman, N. Y., K. G. Arbeev, and M. D. Golubovsky. “A decrease in the dose of the lgl tumor suppressor increases life span of Drosophila in stress and is related to the maternal effect.” Doklady Biological Sciences : Proceedings of the Academy of Sciences of the Ussr, Biological Sciences Sections 406 (January 2006): 37–40. https://doi.org/10.1134/s0012496606010108.Full Text
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Wienke, Andreas, Konstantin G. Arbeev, Isabella Locatelli, and Anatoli I. Yashin. “A comparison of different bivariate correlated frailty models and estimation strategies.” Mathematical Biosciences 198, no. 1 (November 2005): 1–13. https://doi.org/10.1016/j.mbs.2004.11.010.Full Text
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Kulminski, A., A. Yashin, I. Akushevich, S. Ukraintseva, K. Land, K. Arbeev, and K. Manton. “Frailty Index as a Major Indicator of Aging Processes and Mortality in Elderly: Results From Analyses of the National Long Term Care Survey Data,” September 27, 2005.Open Access Copy Link to Item
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Kulminski, A., A. Yashin, S. Ukraintseva, I. Akushevich, K. Arbeev, K. Land, and K. Manton. “Age-Associated Disorders As A Proxy Measure Of Biological Age: Findings From the NLTCS Data,” September 25, 2005.Open Access Copy Link to Item
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Arbeev, K. G., S. V. Ukraintseva, L. S. Arbeeva, and A. I. Yashin. “Decline in human cancer incidence rates at old ages: Age-period-cohort considerations.” Demographic Research 12 (May 13, 2005): 273–300. https://doi.org/10.4054/DemRes.2005.12.11.Full Text
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Arbeev, K. G., S. V. Ukraintseva, L. S. Arbeeva, and A. I. Yashin. “Mathematical models for human cancer incidence rates.” Demographic Research 12 (May 7, 2005): 237–72. https://doi.org/10.4054/DemRes.2005.12.10.Full Text
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Ukraintseva, Svetlana V., Konstantin G. Arbeev, Anatoly I. Michalsky, and Anatoly I. Yashin. “Antiaging treatments have been legally prescribed for approximately thirty years.” Annals of the New York Academy of Sciences 1019 (June 2004): 64–69. https://doi.org/10.1196/annals.1297.014.Full Text
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Anisimov, Vladimir N., Konstantin G. Arbeev, Irina G. Popovich, Mark A. Zabezhinksi, Lyubov S. Arbeeva, and Anatoli I. Yashin. “Is early life body weight a predictor of longevity and tumor risk in rats?” Experimental Gerontology 39, no. 5 (May 2004): 807–16. https://doi.org/10.1016/j.exger.2004.02.004.Full Text
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Anisimov, Vladimir N., Konstantin G. Arbeev, Irina G. Popovich, Mark A. Zabezhinksi, Svetlana V. Rosenfeld, Tatiana S. Piskunova, Lyubov S. Arbeeva, Anna V. Semenchenko, and Anatoli I. Yashin. “Body weight is not always a good predictor of longevity in mice.” Experimental Gerontology 39, no. 3 (March 2004): 305–19. https://doi.org/10.1016/j.exger.2003.12.007.Full Text
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Arbeev, Konstantin G., Alexander A. Butov, Kenneth G. Manton, Igor A. Sannikov, and Anatoli I. Yashin. “Disability trends in gender and race groups of early retirement ages in the USA.” Sozial Und Praventivmedizin 49, no. 2 (January 2004): 142–51. https://doi.org/10.1007/s00038-004-3041-y.Full Text
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Yashin, Anatoli I., Svetlana V. Ukraintseva, Serge I. Boiko, and Konstantin G. Arbeev. “Individual aging and mortality rate: how are they related?” Social Biology 49, no. 3–4 (September 2002): 206–17. https://doi.org/10.1080/19485565.2002.9989059.Full Text
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Yashin, A. I., S. V. Ukraintseva, G. De Benedictis, V. N. Anisimov, A. A. Butov, K. Arbeev, D. A. Jdanov, et al. “Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 56, no. 10 (October 2001): B432–42. https://doi.org/10.1093/gerona/56.10.b432.Full Text
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Book Sections
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Akushevich, I., J. Kravchenko, K. G. Arbeev, S. V. Ukraintseva, K. C. Land, and A. I. Yashin. “Health Effects and Medicare Trajectories: Population-Based Analysis of Morbidity and Mortality Patterns.” In Springer Series on Demographic Methods and Population Analysis, 40:47–93, 2016. https://doi.org/10.1007/978-94-017-7587-8_3.Full Text
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Akushevich, I., J. Kravchenko, K. G. Arbeev, S. V. Ukraintseva, K. C. Land, and A. I. Yashin. “Medical Cost Trajectories and Onset of Age-Associated Diseases.” In Springer Series on Demographic Methods and Population Analysis, 40:143–62, 2016. https://doi.org/10.1007/978-94-017-7587-8_6.Full Text
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Arbeev, K. G., I. Akushevich, A. M. Kulminski, K. C. Land, and A. I. Yashin. “Approaches to Statistical Analysis of Longitudinal Data on Aging, Health, and Longevity: Biodemographic Perspectives.” In Springer Series on Demographic Methods and Population Analysis, 40:241–61, 2016. https://doi.org/10.1007/978-94-017-7587-8_11.Full Text
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Arbeev, K. G., K. C. Land, and A. I. Yashin. “The Latent Class Stochastic Process Model for Evaluation of Hidden Heterogeneity in Longitudinal Data.” In Springer Series on Demographic Methods and Population Analysis, 40:285–302, 2016. https://doi.org/10.1007/978-94-017-7587-8_13.Full Text
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Arbeev, K. G., and A. I. Yashin. “How Biodemographic Approaches Can Improve Statistical Power in Genetic Analyses of Longitudinal Data on Aging, Health, and Longevity.” In Springer Series on Demographic Methods and Population Analysis, 40:303–19, 2016. https://doi.org/10.1007/978-94-017-7587-8_14.Full Text
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Kulminski, A. M., A. I. Yashin, K. G. Arbeev, S. V. Ukraintseva, I. Akushevich, K. C. Land, and E. Stallard. “Continuing the Search for Determinants of Healthy Life Span and Longevity.” In Springer Series on Demographic Methods and Population Analysis, 40:453–63, 2016. https://doi.org/10.1007/978-94-017-7587-8_20.Full Text
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Ukraintseva, S. V., K. G. Arbeev, I. Akushevich, A. M. Kulminski, E. Stallard, and A. I. Yashin. “Factors That May Increase Vulnerability to Cancer and Longevity in Modern Human Populations.” In Springer Series on Demographic Methods and Population Analysis, 40:113–41, 2016. https://doi.org/10.1007/978-94-017-7587-8_5.Full Text
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Yashin, A. I., I. Akushevich, K. G. Arbeev, A. M. Kulminski, and S. V. Ukraintseva. “Integrative Mortality Models for the Study of Aging, Health, and Longevity: Benefits of Combining Data.” In Springer Series on Demographic Methods and Population Analysis, 40:331–52, 2016. https://doi.org/10.1007/978-94-017-7587-8_16.Full Text
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Yashin, A. I., I. Akushevich, K. G. Arbeev, A. M. Kulminski, and S. V. Ukraintseva. “Integrative Mortality Models with Parameters That Have Biological Interpretations.” In Springer Series on Demographic Methods and Population Analysis, 40:321–30, 2016. https://doi.org/10.1007/978-94-017-7587-8_15.Full Text
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Yashin, A. I., K. G. Arbeev, L. S. Arbeeva, I. Akushevich, S. V. Ukraintseva, A. M. Kulminski, E. Stallard, and K. C. Land. “Stochastic Process Models of Mortality and Aging.” In Springer Series on Demographic Methods and Population Analysis, 40:263–84, 2016. https://doi.org/10.1007/978-94-017-7587-8_12.Full Text
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Yashin, A. I., K. G. Arbeev, S. V. Ukraintseva, L. S. Arbeeva, I. Akushevich, J. Kravchenko, A. M. Kulminski, I. Culminskaya, D. Wu, and K. C. Land. “Dynamic Characteristics of Aging-Related Changes as Predictors of Longevity and Healthy Lifespan.” In Springer Series on Demographic Methods and Population Analysis, 40:187–210, 2016. https://doi.org/10.1007/978-94-017-7587-8_8.Full Text
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Yashin, A. I., L. S. Arbeeva, K. G. Arbeev, I. Akushevich, A. M. Kulminski, E. Stallard, and S. V. Ukraintseva. “Age Trajectories of Physiological Indices: Which Factors Influence Them?” In Springer Series on Demographic Methods and Population Analysis, 40:21–45, 2016. https://doi.org/10.1007/978-94-017-7587-8_2.Full Text
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Yashin, A. I., S. V. Ukraintseva, I. Akushevich, A. M. Kulminski, K. G. Arbeev, and E. Stallard. “Evidence for Dependence Among Diseases.” In Springer Series on Demographic Methods and Population Analysis, 40:95–111, 2016. https://doi.org/10.1007/978-94-017-7587-8_4.Full Text
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Yashin, A. I., I. Akushevich, K. Arbeev, A. Kulminski, and S. Ukraintseva. “Methodological aspects of studying human aging, health, and mortality.” In Applied Demography and Public Health, 337–55, 2013. https://doi.org/10.1007/978-94-007-6140-7_19.Full Text
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Scholarly Editions
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Wienke, Andreas, Konstantin G. Arbeev, Isabella Locatelli, and Anatoli I. Yashin. “A simulation study of different correlated frailty models and estimation strategies,” n.d.
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Conference Papers
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Arbeev, Konstantin G., Olivia Bagley, Hongzhe Duan, Arseniy P. Yashkin, Alexander M. Kulminski, Irina V. Culminskaya, Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “Genetics of the measure of physiological dysregulation: findings from the health and retirement study.” In Genetic Epidemiology, 42:687–687. WILEY, 2018.Link to Item
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Zhbannikov, I., K. Arbeev, and A. Yashin. “Applying Stochastic Process Model to Imputation of Censored Longitudinal Data.” In Acm Bcb 2018 Proceedings of the 2018 Acm International Conference on Bioinformatics, Computational Biology, and Health Informatics, 457–64, 2018. https://doi.org/10.1145/3233547.3233591.Full Text
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Arbeev, Konstantin G., Olivia Bagley, Deqing Wu, Mikhail Kovtun, Igor Akushevich, Irina V. Culminskaya, Ilya Y. Zhbannikov, Alexander M. Kulminski, Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “Genetics of the Measure of Physiological Dysregulation: Insights from Longitudinal Data.” In Genetic Epidemiology, 41:674–75. WILEY, 2017.Link to Item
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Kulminski, Alexander M., Yury Loika, Jian Huang, Jiayi Wang, Konstantin G. Arbeev, Olivia Bagley, Matt Duan, Anatoliy Yashin, and Irina Culminskaya. “Genome-wide Meta-analysis of 24 Age-related Phenotypes Leveraging Longitudinal Follow-up and Genetic Heterogeneity Identified Abundant Associations in a Modest Sample of 26,371 Individuals.” In Genetic Epidemiology, 41:666–67. WILEY, 2017.Link to Item
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Zhbannikov, Ilya Y., and Konstantin G. Arbeev. “Stochastic Process Model and Its Applications to Analysis of Longitudinal Data.” In Proceedings of the 8th Acm International Conference on Bioinformatics, Computational Biology,And Health Informatics. ACM, 2017. https://doi.org/10.1145/3107411.3107496.Full Text
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Arbeev, Konstantin G., Liubov S. Arbeeva, Ilya Y. Zhbannikov, Olivia Bagley, Igor Akushevich, Mikhail Kovtun, Alexander M. Kulminski, Irina V. Culminskaya, Svetlana V. Ukraintseva, and Anatoliy I. Yashin. “High-Resolution Analyses of Effects of Polygenic Risk Scores on Time-to-Event Outcomes in Longitudinal Studies.” In Genetic Epidemiology, 40:622–622. WILEY-BLACKWELL, 2016.Link to Item
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“GENE-LEVEL META-ANALYSIS OF CANDIDATE GENES INVOLVED IN ALZHEIMER’S DISEASE AND LONGEVITY.” In The Gerontologist, 56:104–104. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.402.Full Text
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“ANALYSIS OF INTERACTIONS BETWEEN ALZHEIMER’S DISEASE CANDIDATE GENES AND THEIR IMPACT ON LONGEVITY.” In The Gerontologist, 56:103–103. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.400.Full Text
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“PHYSIOLOGICAL DYSREGULATION AS PROMISING MEASURE OF ROBUSTNESS AND RESILIENCE IN AGING STUDIES.” In The Gerontologist, 56:180–81. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.706.Full Text Open Access Copy
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“RELATIONSHIPS AMONG AGING HEALTH AND LONGEVITY IN HRS: CAUSAL ANALYSES USING MENDELIAN RANDOMIZATION.” In The Gerontologist, 56:181–181. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.707.Full Text
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“GENETIC PREDISPOSITION TO AGE-RELATED PHENOTYPES IN THE LIGHT OF EVOLUTION.” In The Gerontologist, 56:49–49. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.204.Full Text
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“PLEIOTROPIC META-ANALYSIS IDENTIFIES SHARED GENETIC CONNECTIONS BETWEEN DISTINCT AGE-RELATED TRAITS.” In The Gerontologist, 56:251–251. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.1006.Full Text
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“GENES WITH PLEIOTROPIC EFFECTS ON AGING-RELATED TRAITS IN HUMANS.” In The Gerontologist, 56:266–266. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.1074.Full Text
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“A NOVEL ALLELIC VARIANT IN A 2Q22 REGION CONFERS RISKS OF MAJOR HUMAN DISEASES AND MORTALITY.” In The Gerontologist, 56:266–266. Oxford University Press (OUP), 2016. https://doi.org/10.1093/geront/gnw162.1072.Full Text
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Yashin, A. I., K. G. Arbeev, L. S. Arbeeva, D. Wu, I. Akushevich, A. Kulminski, M. Kovtun, I. Zhbannikov, and S. V. Ukraintseva. “Resistance to stresses and reliability of biological systems: Insights for genetic studies of human aging, health, and longevity.” In Proceedings 2nd International Symposium on Stochastic Models in Reliability Engineering, Life Science, and Operations Management, Smrlo 2016, 403–9, 2016. https://doi.org/10.1109/SMRLO.2016.70.Full Text Open Access Copy
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Arbeev, Konstantin G., Liubov S. Arbeeva, Olivia Bagley, Hongzhe Duan, Igor Akushevich, Alexander M. Kulminski, Mikhail Kovtun, et al. “On Approaches to Improve Power in Analyses of Genetic Effects on Time-To-Event Outcomes in Longitudinal Studies.” In Genetic Epidemiology, 39:530–530. WILEY-BLACKWELL, 2015.Link to Item
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Kulminski, Alexander M., Yury Loika, Irina Culminskaya, Konstantin G. Arbeev, and Anatoliy I. Yashin. “Unfolding heterogeneity of complex traits has strong potential for advancing GWAS.” In Genetic Epidemiology, 39:562–562. WILEY-BLACKWELL, 2015.Link to Item
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Uemura, Rina, Igor Akushevich, Mikhail Kovtun, Arseniy P. Yashkin, Miaozhu Li, Konstantin G. Arbeev, Svetlana Ukraintseva, and Anatoliy I. Yashin. “Lipofuscin: as an aging marker in nematodes, Caenorhabditis elegans.” In Gerontologist, Vol. 55. OXFORD UNIV PRESS INC, 2015.Link to Item
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“GENETIC HETEROGENEITY AND ITS ROLE IN GWAS OF HUMAN AGING AND LONGEVITY.” In The Gerontologist, 55:859–859. Oxford University Press (OUP), 2015. https://doi.org/10.1093/geront/gnv490.04.Full Text
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“BIODEMOGRAPHIC APPROACHES TO ANALYSES OF POLYGENETIC EFFECTS ON MORTALITY AND AGING.” In The Gerontologist, 55:200–200. Oxford University Press (OUP), 2015. https://doi.org/10.1093/geront/gnv554.16.Full Text
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“PLEIOTROPIC EFFECTS OF GENES ON AGE-RELATED PHENOTYPES: INSIGHTS FROM GERONTOLOGICAL APPROACHES.” In The Gerontologist, 55:460–61. Oxford University Press (OUP), 2015. https://doi.org/10.1093/geront/gnv195.07.Full Text
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“PLEIOTROPIC EFFECTS OF GENES ON PHENOTYPES OF AGING, COMPLEX DISEASE AND LONGEVITY.” In The Gerontologist, 55:459–459. Oxford University Press (OUP), 2015. https://doi.org/10.1093/geront/gnv195.02.Full Text
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“THE ROLE OF BIODEMOGRAPHIC FACTORS IN GENETICS OF AGE-RELATED PHENOTYPES.” In The Gerontologist, 55:460–460. Oxford University Press (OUP), 2015. https://doi.org/10.1093/geront/gnv195.06.Full Text
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Greenup, R. A., K. Arbeev, I. Akushevich, A. Mackey, L. Tolnitch, and E. S. Hwang. “Incidence Patterns of Breast Cancer among Women 35 and Younger at Diagnosis.” In Annals of Surgical Oncology, 21:S56–57. SPRINGER, 2014.Link to Item
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Mackey, A., K. Arbeev, I. Akushevich, R. Greenup, G. Georgiade, J. Horton, M. F. Brennan, and E. S. Hwang. “The Cumulative Impact of Breast Irradiation on Chest Wall Angiosarcoma: A 40-year Outcome Study.” In Annals of Surgical Oncology, 21:S10–S10. SPRINGER, 2014.Link to Item
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Alexander M. Kulminski, Liubov S. Arbeeva, Igor Akushevich, Irina V. Culminskaya, Deqing Wu, and Anatoliy I. Yashin. “Relationship Between the APOE Polymorphism and Risks of Cancer and Alzheimer's Disease: Application of the Genetic Stochastic Process Model.” In Genetic Epidemiology, 36:747–747. WILEY-BLACKWELL, 2012.Link to Item
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Kulminski, Alexander M., Irina Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Liubov Arbeeva, and Anatoli I. Yashin. “The Role of Genes and Life Course in Late Life Diseases.” In Genetic Epidemiology, 36:743–44. WILEY-BLACKWELL, 2012.Link to Item
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Arbeev, Konstantin G., AlexanderM Kulminski, Svetlana V. Ukraintseva, Liubov S. Arbeeva, Igor Akushevich, Irina V. Culminskaya, Deqing Wu, and Anatoliy I. Yashin. “Trade-Off In The Effects Of The APOE Polymorphism On The Ages At Onset Of CVD And Cancer: Insights From The Genetic Stochastic Process Model.” In Genetic Epidemiology, 36:157–157. WILEY-BLACKWELL, 2012.Link to Item
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Kulminski, Alexander, Irina Culminskaya, Svetlana Ukraintseva, Konstantin Arbeev, and Anatoli Yashin. “Complex Modalities Of Gene Action On Phenotypes With Post Reproductive Manifestation: The Case Of Genetic Trade-Off.” In Genetic Epidemiology, 36:162–162. WILEY-BLACKWELL, 2012.Link to Item
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Liubov S. Arbeeva, Igor Akushevich, Alexander M. Kulminski, Deqing Wu, and Anatoliy I. Yashin. “Evaluation of Effects of Genetic polymorphisms and Age Trajectories of Physiological Indices on survival.” In Genetic Epidemiology, 34:965–66. WILEY-BLACKWELL, 2010.Link to Item
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Liubov S. Arbeeva, Alexander M. Kulminski, Igor Akushevich, and Anatoli I. Yashin. “Evaluation of Genotype-specific Age Patterns of Hazard Rates Using Joint Analysis of Genetic and Non-genetic Subsamples of Longitudinal Data.” In Genetic Epidemiology, 33:822–822. WILEY-LISS, 2009.Link to Item
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Kulminski, Alexander, Svetlana Ukraintseva, Irina Culminskaya, Konstantin Arbeev, Igor Akushevich, and Anatoli Yashin. “The Role of Polymorphisms in the ACE and ADRB2 Genes in Incidence of Myocardial Infarction in Framingham Heart Study Participants.” In Genetic Epidemiology, 33:824–824. WILEY-LISS, 2009.Link to Item
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Kulminski, Alexander, Svetlana Ukraintseva, Konstantin Arbeev, Irina Culminskaya, and Anatoli Yashin. “Polymorphisms in the Angiotensin-Converting Enzyme (ACE) Gene as Determinants of Cardiovascular Diseases Risks and Short Life in Framingham Heart Study.” In Genetic Epidemiology, 33:822–822. WILEY-LISS, 2009.Link to Item
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Arbeev, K. G., A. I. Yashin, I. Akushevich, A. M. Kulminski, L. S. Arbeeva, L. Akushevich, and S. V. Ukraintseva. “Stochastic Model for Joint Analysis of Genetic and Non-Genetic Data from Longitudinal Studies of Aging, Health and Longevity.” In Genetic Epidemiology, 32:678–678. WILEY-LISS, 2008.Link to Item
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Matteini, A. M., M. D. Fallin, C. M. Kammerer, N. Schupf, A. I. Yashin, R. Mayeux, R. G. Barr, et al. “Heritability of Endophenotypes of Pulmonary & Physical Function in Long Life Family Study.” In Genetic Epidemiology, 32:706–7. WILEY-LISS, 2008.Link to Item
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Yashin, A. I., I. V. Culminskaya, K. G. Arbeev, S. V. Ukraintseva, I. Akushevich, and A. Kulminski. “Effects of ACE D/I Polymorphism and 11 SNPs Heterozygosity in the Same Gene on Health Risks in Framingham Study.” In Genetic Epidemiology, 32:722–722. WILEY, 2008.Link to Item
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Yashin, A. I., S. V. Ukraintseva, K. G. Arbeev, I. V. Culminskaya, I. Akushevich, and A. Kulminski. “Interacting Effect of ACE D/I Polymorphism and Smoking on Health Risks in Framingham Study.” In Genetic Epidemiology, 32:722–23. WILEY, 2008.Link to Item
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Arbeev, Konstantin G., Svetlana V. Ukraintseva, Lyubov S. Arbeeva, and Anatoli I. Yashin. “Difference between Male and Female Cancer Incidence Rates: How Can It Be Explained?,” 12–22. Springer-Verlag, n.d. https://doi.org/10.1007/0-387-26023-4_2.Full Text
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