Kafui Dzirasa
Associate Professor of Psychiatry and Behavioral Sciences
Current Appointments & Affiliations
- Associate Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Brain Stimulation and Neurophysiology, Psychiatry & Behavioral Sciences 2017
- Assistant Professor in Neurobiology, Neurobiology, Basic Science Departments 2013
- Assistant Professor in Neurosurgery, Neurosurgery, Neurosurgery 2017
- Associate Professor in Neurobiology, without tenure, Neurobiology, Basic Science Departments 2017
- Associate Professor in Neurobiology, without tenure, Neurobiology, Basic Science Departments 2017
- Associate Professor in Neurobiology, without tenure, Neurobiology, Basic Science Departments 2017
- Investigator in the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2013
Contact Information
- Box 3209 Medctr, Durham, NC 27710
- Bryan Research Bldg, Room 361, Durham, NC 27710
-
kafui.dzirasa@duke.edu
(919) 613-2832
- Background
-
Education, Training, & Certifications
- Resident in Psychiatry, Psychiatry, Duke University School of Medicine 2010 - 2016
- M.D., Duke University School of Medicine 2009
- Ph.D., Duke University 2007
-
Duke Appointment History
- Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Brain Stimulation and Neurophysiology, Psychiatry & Behavioral Sciences 2013 - 2017
- Assistant Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2014 - 2017
- Assistant Research Professor in Neurobiology, Neurobiology, Basic Science Departments 2012 - 2013
- Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Brain Stimulation and Neurophysiology, Psychiatry & Behavioral Sciences 2013
- Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Geriatric Behavioral Health, Psychiatry & Behavioral Sciences 2009 - 2013
- Instructor, Temporary in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Geriatric Behavioral Health, Psychiatry & Behavioral Sciences 2009
- Recognition
-
In the News
-
MAR 1, 2018 Duke University -
JUN 23, 2017 -
FEB 15, 2017 -
OCT 18, 2016 -
AUG 9, 2016 -
JUN 23, 2016 -
MAY 9, 2016 -
APR 14, 2016 PBS “Ride the Tiger” documentary -
FEB 19, 2016 -
JUN 26, 2015 -
JUL 30, 2014 USA Today -
JUL 29, 2014
-
- Research
-
Selected Grants
- Akt/GSK-3 Signaling Cascade and the Actions of Dopamine awarded by National Institutes of Health 2005 - 2020
- Simultaneous and Bidirectional Chemogenetic Control of Mesolimbic and Nigrostriatal Circuits awarded by National Institutes of Health 2018 - 2020
- Unraveling the neural gate to consciousness awarded by W.M. Keck Foundation 2016 - 2019
- Enabling Stress Resistance awarded by National Institutes of Health 2012 - 2018
- Environmental Toxins and Microglia-Synapse Interactions in Autism awarded by Massachusetts General Hospital 2016 - 2018
- Basic predoctoral training in neuroscience awarded by National Institutes of Health 1992 - 2018
- A novel neural circuit analysis paradigm to model autism in mice awarded by National Institutes of Health 2014 - 2017
- BRAIN EAGER: Bayesian Models of Translational Neural Networks: Motivation and Reward awarded by National Science Foundation 2014 - 2017
- The 5-HT theory of depression tested in a naturalistic model of 5-HT deficiency awarded by National Institutes of Health 2006 - 2017
- Characterizing sensorimotor gaiting dysfunction in mouse models of schizophrenia awarded by National Institutes of Health 2013 - 2016
- Publications & Artistic Works
-
Selected Publications
-
Conference Papers
- Ulrich, K, Carlson, DE, Dzirasa, K, and Carin, L. "GP kernels for cross-spectrum analysis." January 1, 2015.
- Carlson, DE, Borg, JS, Dzirasa, K, and Carin, L. "On the relationship between LFP & spiking data." January 1, 2014.
- Ulrich, K, Carlson, DE, Lian, W, Borg, JS, Dzirasa, K, and Carin, L. "Analysis of brain states from multi-region LFP time-series." January 1, 2014.
-
Journal Articles
- Hultman, R, Ulrich, K, Sachs, BD, Blount, C, Carlson, DE, Ndubuizu, N, Bagot, RC, Parise, EM, Vu, M-AT, Gallagher, NM, Wang, J, Silva, AJ, Deisseroth, K, Mague, SD, Caron, MG, Nestler, EJ, Carin, L, and Dzirasa, K. "Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability." Cell 173, no. 1 (March 2018): 166-180.e14. Full Text
- Vu, M-AT, Adalı, T, Ba, D, Buzsáki, G, Carlson, D, Heller, K, Liston, C, Rudin, C, Sohal, VS, Widge, AS, Mayberg, HS, Sapiro, G, and Dzirasa, K. "A Shared Vision for Machine Learning in Neuroscience." The Journal of neuroscience : the official journal of the Society for Neuroscience 38, no. 7 (February 2018): 1601-1607. Full Text
- Dzirasa, K. "Neuronal suppression causing depression?." Science Translational Medicine 10, no. 425 (January 24, 2018). (Review) Full Text
- Dzirasa, K. "Brain leak, mind bleak." Science Translational Medicine 9, no. 419 (December 6, 2017). Full Text
- Carlson, D, David, LK, Gallagher, NM, Vu, M-AT, Shirley, M, Hultman, R, Wang, J, Burrus, C, McClung, CA, Kumar, S, Carin, L, Mague, SD, and Dzirasa, K. "Dynamically Timed Stimulation of Corticolimbic Circuitry Activates a Stress-Compensatory Pathway." Biological psychiatry 82, no. 12 (December 2017): 904-913. Full Text
- Dzirasa, K. "In the mood for food." Science Translational Medicine 9, no. 407 (September 13, 2017): eaao6124-eaao6124. Full Text
- Dzirasa, K. "A brilliant approach to study the basis of intelligence?." Science Translational Medicine 9, no. 401 (August 2, 2017): eaao0978-eaao0978. Full Text
- Dzirasa, K. "When they go low, we go high." Science translational medicine 9, no. 395 (June 2017). Full Text
- Schaich Borg, J, Srivastava, S, Lin, L, Heffner, J, Dunson, D, Dzirasa, K, and de Lecea, L. "Rat intersubjective decisions are encoded by frequency-specific oscillatory contexts." Brain and behavior 7, no. 6 (June 2017): e00710-. Full Text Open Access Copy
- Dzirasa, K. "Working memory: The real VIP." Science translational medicine 9, no. 389 (May 2017). Full Text
- Dzirasa, K. "The neural substrates of super memory." Science translational medicine 9, no. 383 (March 2017). Full Text
- Ade, KK, Wan, Y, Hamann, HC, O'Hare, JK, Guo, W, Quian, A, Kumar, S, Bhagat, S, Rodriguiz, RM, Wetsel, WC, Conn, PJ, Dzirasa, K, Huber, KM, and Calakos, N. "Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice." Biological psychiatry 80, no. 7 (October 2016): 522-533. Full Text
- Hultman, R, Mague, SD, Li, Q, Katz, BM, Michel, N, Lin, L, Wang, J, David, LK, Blount, C, Chandy, R, Carlson, D, Ulrich, K, Carin, L, Dunson, D, Kumar, S, Deisseroth, K, Moore, SD, and Dzirasa, K. "Dysregulation of Prefrontal Cortex-Mediated Slow-Evolving Limbic Dynamics Drives Stress-Induced Emotional Pathology." Neuron 91, no. 2 (July 2016): 439-452. Full Text
- Wang, X, Bey, AL, Katz, BM, Badea, A, Kim, N, David, LK, Duffney, LJ, Kumar, S, Mague, SD, Hulbert, SW, Dutta, N, Hayrapetyan, V, Yu, C, Gaidis, E, Zhao, S, Ding, J-D, Xu, Q, Chung, L, Rodriguiz, RM, Wang, F, Weinberg, RJ, Wetsel, WC, Dzirasa, K, Yin, H, and Jiang, Y-H. "Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism." Nature communications 7 (May 10, 2016): 11459-. Full Text Open Access Copy
- Gordon, JA, and Dzirasa, K. "Animal models of psychiatric disorders." Neuroscience 321 (May 2016): 1-2. Full Text
- Sidor, MM, Spencer, SM, Dzirasa, K, Parekh, PK, Tye, KM, Warden, MR, Arey, RN, Enwright, JF, Jacobsen, JPR, Kumar, S, Remillard, EM, Caron, MG, Deisseroth, K, and McClung, CA. "Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice." Molecular psychiatry 20, no. 11 (November 2015): 1406-1419. Full Text
- Sidor, MM, Spencer, SM, Dzirasa, K, Parekh, PK, Tye, KM, Warden, MR, Arey, RN, Enwright, JF, Jacobsen, JPR, Kumar, S, Remillard, EM, Caron, MG, Deisseroth, K, and McClung, CA. "Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice." Molecular psychiatry 20, no. 11 (November 2015): 1479-1480. Full Text
- Borg, JS, Vu, M-A, Badea, C, Badea, A, Johnson, GA, and Dzirasa, K. "Localization of Metal Electrodes in the Intact Rat Brain Using Registration of 3D Microcomputed Tomography Images to a Magnetic Resonance Histology Atlas." eNeuro 2, no. 4 (July 2015). Full Text Open Access Copy
- Dzirasa, K, Krishnan, RR, and Williams, RS. "Incubating the research independence of a medical scientist training program graduate: A case study." Academic Medicine 90, no. 2 (February 6, 2015): 176-179. Full Text
- Dzirasa, K, Krishnan, RR, and Williams, RS. "Incubating the research independence of a medical scientist training program graduate: a case study." Academic medicine : journal of the Association of American Medical Colleges 90, no. 2 (February 2015): 176-179. Full Text
- Kumar, S, Hultman, R, Hughes, D, Michel, N, Katz, BM, and Dzirasa, K. "Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress." Nature communications 5 (July 29, 2014): 4537-. Full Text
- Dzirasa, K, Kumar, S, Sachs, BD, Caron, MG, and Nicolelis, MAL. "Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency." J Neurosci 33, no. 10 (March 6, 2013): 4505-4513. Full Text Link to Item
- Kumar, S, Black, SJ, Hultman, R, Szabo, ST, DeMaio, KD, Du, J, Katz, BM, Feng, G, III, CHE, and Dzirasa, K. "Cortical Control of Affective Networks." JOURNAL OF NEUROSCIENCE 33, no. 3 (January 16, 2013): 1116-1129. Full Text Link to Item
- Dzirasa, K, and Lisanby, SH. "How does deep brain stimulation work?." Biol Psychiatry 72, no. 11 (December 1, 2012): 892-894. Full Text Link to Item
- Dzirasa, K, and Covington, HE. "Increasing the validity of experimental models for depression." Ann N Y Acad Sci 1265 (August 2012): 36-45. (Review) Full Text Link to Item
- Dzirasa, K, McGarity, DL, Bhattacharya, A, Kumar, S, Takahashi, JS, Dunson, D, McClung, CA, and Nicolelis, MAL. "Impaired limbic gamma oscillatory synchrony during anxiety-related behavior in a genetic mouse model of bipolar mania." J Neurosci 31, no. 17 (April 27, 2011): 6449-6456. Full Text Link to Item
- Dzirasa, K, Fuentes, R, Kumar, S, Potes, JM, and Nicolelis, MAL. "Chronic in vivo multi-circuit neurophysiological recordings in mice." J Neurosci Methods 195, no. 1 (January 30, 2011): 36-46. Full Text Link to Item
- Dzirasa, K, Coque, L, Sidor, MM, Kumar, S, Dancy, EA, Takahashi, JS, McClung, CA, and Nicolelis, MAL. "Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania." J Neurosci 30, no. 48 (December 1, 2010): 16314-16323. Full Text Link to Item
- Fuentes, R, Dzirasa, K, and Nicolelis, MAL. "Acute Effects of Spinal Cord Stimulation in Large-Scale Brain Circuits in a Transgenic Mouse Parkinson's Model." MOVEMENT DISORDERS 25 (September 15, 2010): S630-S630. Link to Item
- Dzirasa, K, Phillips, HW, Sotnikova, TD, Salahpour, A, Kumar, S, Gainetdinov, RR, Caron, MG, and Nicolelis, MAL. "Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony." J Neurosci 30, no. 18 (May 5, 2010): 6387-6397. Full Text Link to Item
- Dzirasa, K, Ramsey, AJ, Takahashi, DY, Stapleton, J, Potes, JM, Williams, JK, Gainetdinov, RR, Sameshima, K, Caron, MG, and Nicolelis, MAL. "Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling." J Neurosci 29, no. 25 (June 24, 2009): 8215-8224. Full Text Link to Item
- Dzirasa, K, Santos, LM, Ribeiro, S, Stapleton, J, Gainetdinov, RR, Caron, MG, and Nicolelis, MAL. "Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep." PLoS One 4, no. 4 (2009): e5238-. Full Text Link to Item
- Santos, LM, Dzirasa, K, Kubo, R, Silva, MTA, Ribeiro, S, Sameshima, K, Valle, AC, and Timo-Iaria, C. "Baseline hippocampal theta oscillation speeds correlate with rate of operant task acquisition." Behav Brain Res 190, no. 1 (June 26, 2008): 152-155. Full Text Link to Item
- Dzirasa, K, Ribeiro, S, Costa, R, Santos, LM, Lin, S-C, Grosmark, A, Sotnikova, TD, Gainetdinov, RR, Caron, MG, and Nicolelis, MAL. "Dopaminergic control of sleep-wake states." J Neurosci 26, no. 41 (October 11, 2006): 10577-10589. Full Text Link to Item
- Dzirasa, K, Ribeiro, S, Costa, R, Santos, LM, Lin, S-C, Grosmark, A, Sotnikova, TD, Gainetdinov, RR, Caron, MG, and Nicolelis, MAL. "Erratum: Dopaminergic Control of Sleep-Wake States (Journal of Neuroscience (October 11, 2006) (10577-10589))." Journal of Neuroscience 26, no. 47 (2006).
- Semple, KT, Lee, PH, Reid, BJ, and Dzirasa, K. "Bioavailability of cable insulating oil to soil biota." Battelle Memorial Institute International In Situ and On-Site Bioreclamation Symposium Proceedings 5 (1999): 8/--.
-
- Teaching & Mentoring
-
Recent Courses
- NEUROBIO 393: Research Independent Study 2018
- NEUROBIO 793: Research in Neurobiology 2018
- NEUROSCI 493: Research Independent Study 1 2018
- NEUROSCI 494: Research Independent Study 2 2018
- NEUROSCI 150: Research Practicum 2017
- NEUROSCI 495: Research Independent Study 3 2017
- NEUROSCI 496: Research Independent Study 4 2017
- NEUROSCI 755: Interdisciplinary Program in Cognitive Neuroscience (IPCN) Independent Research Rotation 2016
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.
