Research Interests
- Outcomes and novel biomarkers in patients with heart failure undergoing surgery
- Modification of pulmonary circulation for perioperative end-organ protection
- Thromboinflammation in lung injury and extracorporeal life support
- Thromboembolic events after treatment for acquired bleeding disorders in cardiovascular surgery
Selected Grants
Integrated Training in Anesthesiology Research
Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 1996 - 2031ATN-108
Clinical TrialPrincipal Investigator · Awarded by Octapharma AG · 2024 - 2027Trajectories of Recovery after Intravenous propofol versus inhaled VolatilE anesthesia: THRIVE Trial
ResearchPrincipal Investigator · Awarded by University of Michigan · 2023 - 2026Prospective, multicentre, active-control randomised trial comparing 4-factor prothrombin complex concentrate with frozen plasma in bleeding adult cardiac surgical patients
Clinical TrialPrincipal Investigator · Awarded by Octapharma AG · 2022 - 2025Right Ventricular Metabolic Dysregulation after Surgery for Heart Failure
ResearchPrincipal Investigator · Awarded by International Anesthesia Research Society · 2021 - 2023LEX-209 Octapharma
Clinical TrialPrincipal Investigator · Awarded by Octapharma AG · 2017 - 2018Fellowships, Gifts & Other Supported Research
Integrated Training in Anesthesiology & Critical Care Research ·
February 2018
- February 2021
Awarded by: NIH T32 GM008600
INSPIRE-FLO: Inhaled Selective Pulmonary Vasodilation for Advanced Heart Failure Therapies and Lung Transplantation Outcomes ·
May 2017
- December 2021
Principal Investigator ·
Awarded by: Duke University Health System
Randomized, controlled, triple-blinded trial comparing the ability of inhaled nitric oxide and aerosolized epoprostenol with extended stability (iPGI2,Veletri®) to reduce the incidence of (1) right-sided heart failure after advanced left-heart replacement therapies (durable LVAD, heart transplantation); and (2) severe primary graft dysfunction after lung transplantation.