Karen Chiswell | Scholars@Duke

Karen Chiswell
Statistical Scientist

Ph.D., North Carolina State University - 2007

I work closely with clinical and quantitative colleagues to provide statistical leadership, guidance and mentoring on the design, execution, and analysis of clinical research studies. My work includes design and analysis of observational studies (including large cardiovascular registries, and clinical care databases linked with electronic health record data) and early-phase trials in pediatric populations. My statistical interests include study design, linear and non-linear mixed effects models, survival analysis, biology- and mechanism-based models, and statistical thinking and learning.

Current Appointments & Affiliations

Statistical Scientist, Duke Clinical Research Institute, Institutes and Centers

Contact Information

Durham Center, 300 West Morgan Street, Durham, NC 27701
karen.chiswell@duke.edu +1 919 668 8395

Expertise
Subject Headings
Research
Selected Grants
- VCID Biomarkers Coordinating Center awarded by Massachusetts General Hospital 2022 - 2025
- The North Carolina Congenital Heart Disease Surveillance Network awarded by Centers for Disease Control and Prevention 2019 - 2024
- iPRO (Inspiratory Pulmonary Rehabilitation for Children with Obesity and Asthma) awarded by American Lung Association 2022 - 2024
- Infrastructure for Musculoskeletal Pediatric Acute Care Clinical Trials (IMPACCT) awarded by Ann & Robert H Lurie Children's Hospital of Chicago 2021 - 2023
- Pathways to cardiovascular disease prevention and impact of specialty referral in under-represented racial/ethnic minorities with HIV awarded by National Institutes of Health 2018 - 2023
- PTN 2.0- TO 3 - Option 3 - BPCA Concept Development and Clinical Trial Readiness Support awarded by National Institute for Child Health & Human Develo 2021 - 2022
- North Carolina Congenital Heart Defects Surveillance Network awarded by Centers for Disease Control and Prevention 2015 - 2020
- Using AACT - to answer Oncology landscape portfolio of open trials awarded by American Cancer Society Cancer Action Network 2017 - 2018
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Olsen, C., Mandawat, A., Sun, J.-L., Triana, T., Chiswell, K., & Karra, R. (2022). Recovery of left ventricular function is associated with improved outcomes in LVAD recipients. J Heart Lung Transplant, 41(8), 1055–1062. https://doi.org/10.1016/j.healun.2022.03.008
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  - Pokorney, S. D., Berchuck, S. I., Chiswell, K., Sun, J.-L., Thomas, L., Jones, W. S., … Piccini, J. P. (2022). Atrial branch coronary artery stenosis as a mechanism for atrial fibrillation. Heart Rhythm, 19(8), 1237–1244. https://doi.org/10.1016/j.hrthm.2021.12.020
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  - Bergin, S. P., Calvert, S. B., Farley, J., Sun, J.-L., Chiswell, K., Dieperink, W., … Hullegie, S. J. (2022). PROPHETIC EU: Prospective Identification of Pneumonia in Hospitalized Patients in the Intensive Care Unit in European and United States Cohorts. Open Forum Infect Dis, 9(7), ofac231. https://doi.org/10.1093/ofid/ofac231
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  - Keshvani, N., Mehta, A., Alger, H. M., Rutan, C., Williams, J., Zhang, S., … Pandey, A. (2022). Heart failure quality of care and in-hospital outcomes during the COVID-19 pandemic: findings from the Get With The Guidelines-Heart Failure registry. Eur J Heart Fail, 24(6), 1117–1128. https://doi.org/10.1002/ejhf.2484
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  - Shah, N. P., Clare, R. M., Chiswell, K., Navar, A. M., Shah, B. R., & Peterson, E. D. (2022). Trends of blood pressure control in the U.S. during the COVID-19 pandemic. Am Heart J, 247, 15–23. https://doi.org/10.1016/j.ahj.2021.11.017
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  - Vaduganathan, M., Greene, S. J., Zhang, S., Solomon, N., Chiswell, K., Devore, A. D., … Fonarow, G. C. (2022). Projected Clinical Benefits of Implementation of SGLT-2 Inhibitors Among Medicare Beneficiaries Hospitalized for Heart Failure. J Card Fail, 28(4), 554–563. https://doi.org/10.1016/j.cardfail.2021.11.010
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  - Carnicelli, A. P., Clare, R. M., Hofmann, P., Chiswell, K., DeVore, A. D., Vemulapalli, S., … Mentz, R. J. (2022). Clinical trajectory of patients with a worsening heart failure event and reduced ventricular ejection fraction. Am Heart J, 245, 110–116. https://doi.org/10.1016/j.ahj.2021.12.003
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  - Pasquali, S. K., Thibault, D., Hall, M., Chiswell, K., Romano, J. C., Gaynor, J. W., … Jacobs, J. P. (2022). Evolving Cost-Quality Relationship in Pediatric Heart Surgery. Ann Thorac Surg, 113(3), 866–873. https://doi.org/10.1016/j.athoracsur.2021.05.050
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  - Bloomfield, G. S., Alenezi, F., Chiswell, K., Dunning, A., Okeke, N. L., & Velazquez, E. J. (2022). Progression of cardiac structure and function in people with human immunodeficiency virus. Echocardiography, 39(2), 268–277. https://doi.org/10.1111/echo.15302
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  - Hein, A. M., Scialla, J. J., Sun, J.-L., Greene, S. J., Shaw, L. K., Chiswell, K., … Mentz, R. J. (2021). Estimated Glomerular Filtration Rate Variability in Patients With Heart Failure and Chronic Kidney Disease. J Card Fail, 27(11), 1175–1184. https://doi.org/10.1016/j.cardfail.2021.04.016
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  - Long, J. B., Engorn, B. M., Hill, K. D., Feng, L., Chiswell, K., Jacobs, M. L., … Goswami, D. (2021). Postoperative Hematocrit and Adverse Outcomes in Pediatric Cardiac Surgery Patients: A Cross-Sectional Study From the Society of Thoracic Surgeons and Congenital Cardiac Anesthesia Society Database Collaboration. Anesth Analg, 133(5), 1077–1088. https://doi.org/10.1213/ANE.0000000000005416
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  - Luo, N., O’Connor, C. M., Chiswell, K., Anstrom, K. J., Newby, L. K., & Mentz, R. J. (2021). Survival in Patients With Nonischemic Cardiomyopathy With Preserved vs Reduced Ejection Fraction. Cjc Open, 3(11), 1333–1340. https://doi.org/10.1016/j.cjco.2021.06.007
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  - Nanna, M. G., Wang, T. Y., Chiswell, K., Sun, J. L., Vemulapalli, S., Hoffmann, U., … Douglas, P. S. (2021). Estimating the real-world performance of the PROMISE minimal-risk tool. Am Heart J, 239, 100–109. https://doi.org/10.1016/j.ahj.2021.05.016
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  - Williams, J. L., Torok, R. D., D’Ottavio, A., Spears, T., Chiswell, K., Forestieri, N. E., … Li, J. S. (2021). Causes of Death in Infants and Children with Congenital Heart Disease. Pediatr Cardiol, 42(6), 1308–1315. https://doi.org/10.1007/s00246-021-02612-2
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  - Fraser, C. D., Ravekes, W., Thibault, D., Scully, B., Chiswell, K., Giuliano, K., … Hibino, N. (2021). Diaphragm Paralysis After Pediatric Cardiac Surgery: An STS Congenital Heart Surgery Database Study. Ann Thorac Surg, 112(1), 139–146. https://doi.org/10.1016/j.athoracsur.2020.05.175
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  - Serfas, J. D., Thibault, D., Andersen, N. D., Chiswell, K., Jacobs, J. P., Jacobs, M. L., … Hill, K. D. (2021). The Evolving Surgical Burden of Fontan Failure: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database. Ann Thorac Surg, 112(1), 179–187. https://doi.org/10.1016/j.athoracsur.2020.05.174
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  - Yankey, G. S., Jackson, L. R., Marts, C., Chiswell, K., Wu, A., Ugowe, F., … Thomas, K. L. (2021). African American-Caucasian American differences in aortic valve replacement in patients with severe aortic stenosis. Am Heart J, 234, 111–121. https://doi.org/10.1016/j.ahj.2021.01.005
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  - Lunyera, J., Clare, R. M., Chiswell, K., Scialla, J. J., Pun, P. H., Thomas, K. L., … Diamantidis, C. J. (2021). Racial Differences in AKI Incidence Following Percutaneous Coronary Intervention. J Am Soc Nephrol, 32(3), 654–662. https://doi.org/10.1681/ASN.2020040502
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  - Nanna, M. G., Peterson, E. D., Chiswell, K., Overton, R. A., Nelson, A. J., Kong, D. F., & Navar, A. M. (2021). The incremental value of angiographic features for predicting recurrent cardiovascular events: Insights from the Duke Databank for Cardiovascular Disease. Atherosclerosis, 321, 1–7. https://doi.org/10.1016/j.atherosclerosis.2021.02.004
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  - Riggs, K. W., Zafar, F., Jacobs, M. L., Jacobs, J. P., Thibault, D., Guleserian, K. J., … Tweddell, J. S. (2021). Tracheal surgery for airway anomalies associated with increased mortality in pediatric patients undergoing heart surgery: Society of Thoracic Surgeons Database analysis. J Thorac Cardiovasc Surg, 161(3), 1112-1121.e7. https://doi.org/10.1016/j.jtcvs.2020.10.149
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  - Zeitler, E. P., Cooper, L. B., Clare, R. M., Chiswell, K., Lowenstern, A., Rogers, J. G., … Mentz, R. J. (2021). OptiVol for Volume Assessment in Patients With Continuous Flow Left Ventricular Assist Device. Asaio J, 67(2), 192–195. https://doi.org/10.1097/MAT.0000000000001244
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  - Yamada, M. M., Rosamilia, M. B., Chiswell, K. E., D’Ottavio, A., Spears, T., Osgood, C., … Landstrom, A. P. (2021). Risk Factors for Sudden Infant Death in North Carolina. Front Pediatr, 9, 770803. https://doi.org/10.3389/fped.2021.770803
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  - Zeitouni, M., Clare, R. M., Chiswell, K., Abdulrahim, J., Shah, N., Pagidipati, N. P., … Jones, W. S. (2020). Risk Factor Burden and Long-Term Prognosis of Patients With Premature Coronary Artery Disease. J Am Heart Assoc, 9(24), e017712. https://doi.org/10.1161/JAHA.120.017712
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  - Bergin, S. P., Coles, A., Calvert, S. B., Farley, J., Powers, J. H., Zervos, M. J., … Holland, T. L. (2020). PROPHETIC: Prospective Identification of Pneumonia in Hospitalized Patients in the ICU. Chest, 158(6), 2370–2380. https://doi.org/10.1016/j.chest.2020.06.034
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  - Grubb, A. F., Pumill, C. A., Greene, S. J., Wu, A., Chiswell, K., & Mentz, R. J. (2020). Tobacco smoking in patients with heart failure and coronary artery disease: A 20-year experience at Duke University Medical Center. Am Heart J, 230, 25–34. https://doi.org/10.1016/j.ahj.2020.09.011
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  - Pasquali, S. K., Chiswell, K., Hall, M., Thibault, D., Romano, J. C., Gaynor, J. W., … Jacobs, J. P. (2020). Estimating Resource Utilization in Congenital Heart Surgery. Ann Thorac Surg, 110(3), 962–968. https://doi.org/10.1016/j.athoracsur.2020.01.013
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  - Zeitouni, M., Nanna, M. G., Sun, J.-L., Chiswell, K., Peterson, E. D., & Navar, A. M. (2020). Performance of Guideline Recommendations for Prevention of Myocardial Infarction in Young Adults. J Am Coll Cardiol, 76(6), 653–664. https://doi.org/10.1016/j.jacc.2020.06.030
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  - Goldstein, S. A., D’Ottavio, A., Spears, T., Chiswell, K., Hartman, R. J., Krasuski, R. A., … Li, J. S. (2020). Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease. J Am Heart Assoc, 9(14), e016400. https://doi.org/10.1161/JAHA.119.016400
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  - Carnicelli, A. P., Clare, R., Chiswell, K., Lytle, B., Bjursell, M., Perl, S., … Mentz, R. J. (2020). Comparison of Characteristics and Outcomes of Patients With Heart Failure With Preserved Ejection Fraction With Versus Without Hyperuricemia or Gout. Am J Cardiol, 127, 64–72. https://doi.org/10.1016/j.amjcard.2020.04.026
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  - Patel, P. A., Ambrosy, A. P., Phelan, M., Alenezi, F., Chiswell, K., Van Dyke, M. K., … Velazquez, E. J. (2020). Association between systolic ejection time and outcomes in heart failure by ejection fraction. European Journal of Heart Failure, 22(7), 1174–1182. https://doi.org/10.1002/ejhf.1659
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  - Lumsden, R. H., Pagidipati, N. J., Phelan, M. P., Chiswell, K., & Peterson, E. D. (2020). Prevalence and Management of Adult Obesity in a Large U.S. Academic Health System. Am J Prev Med, 58(6), 817–824. https://doi.org/10.1016/j.amepre.2020.01.018
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  - Ross, F. J., Radman, M., Jacobs, M. L., Sassano-Miguel, C., Joffe, D. C., Hill, K. D., … Latham, G. J. (2020). Associations between anthropometric indices and outcomes of congenital heart operations in infants and young children: An analysis of data from the Society of Thoracic Surgeons Database. Am Heart J, 224, 85–97. https://doi.org/10.1016/j.ahj.2020.03.012
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  - Tran, G., Harker, M., Chiswell, K., Unger, J. M., Fleury, M. E., Hirsch, B., … Zafar, S. Y. (2020). Feasibility of Cancer Clinical Trial Enrollment Goals Based on Cancer Incidence. Jco Clin Cancer Inform, 4, 35–49. https://doi.org/10.1200/CCI.19.00088
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  - DeVore, A. D., Yow, E., Krucoff, M. W., Sherwood, M. W., Shaw, L. K., Chiswell, K., … Velazquez, E. J. (2019). Percutaneous coronary intervention outcomes in patients with stable coronary disease and left ventricular systolic dysfunction. Esc Heart Fail, 6(6), 1233–1242. https://doi.org/10.1002/ehf2.12510
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  - Chew, J. D., Hill, K. D., Jacobs, M. L., Jacobs, J. P., Killen, S. A. S., Godown, J., … Soslow, J. H. (2019). Congenital Heart Surgery Outcomes in Turner Syndrome: The Society of Thoracic Surgeons Database Analysis. Ann Thorac Surg, 108(5), 1430–1437. https://doi.org/10.1016/j.athoracsur.2019.05.047
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  - Shelburne, N. J., Parikh, K. S., Chiswell, K., Shaw, L. K., Sivak, J., Arges, K., … Rajagopal, S. (2019). Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension. Am J Cardiol, 124(8), 1298–1304. https://doi.org/10.1016/j.amjcard.2019.07.026
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  - Pagidipati, N. J., Mudrick, D. W., Chiswell, K., Brucker, A., Peterson, E. D., & Douglas, P. S. (2019). Sex differences in long-term outcomes of patients across the spectrum of coronary artery disease (vol 206, pg 51, 2018). American Heart Journal, 216, 150–150.
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  - Jacobs, M. L., Jacobs, J. P., Hill, K. D., O’Brien, S. M., Pasquali, S. K., Vener, D., … Fernandez, F. G. (2019). The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2019 Update on Research. Ann Thorac Surg, 108(3), 671–679. https://doi.org/10.1016/j.athoracsur.2019.07.002
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  - Sullivan, L. T., Mulder, H., Chiswell, K., Shaw, L. K., Wang, T. Y., Jackson, L. R., & Thomas, K. L. (2019). Racial differences in long-term outcomes among black and white patients with drug-eluting stents. Am Heart J, 214, 46–53. https://doi.org/10.1016/j.ahj.2019.04.005
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  - Jaffe, I. S., Chiswell, K., & Tsalik, E. L. (2019). A Decade On: Systematic Review of ClinicalTrials.gov Infectious Disease Trials, 2007-2017. Open Forum Infect Dis, 6(6), ofz189. https://doi.org/10.1093/ofid/ofz189
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  - Kogon, B. E., Oster, M. E., Wallace, A., Chiswell, K., Hill, K. D., Cox, M. L., … Jacobs, M. L. (2019). Readmission After Pediatric Cardiothoracic Surgery: An Analysis of The Society of Thoracic Surgeons Database. Ann Thorac Surg, 107(6), 1816–1823. https://doi.org/10.1016/j.athoracsur.2019.01.009
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  - Stewart, R. A. H., Held, C., Krug-Gourley, S., Waterworth, D., Stebbins, A., Chiswell, K., … White, H. (2019). Cardiovascular and Lifestyle Risk Factors and Cognitive Function in Patients With Stable Coronary Heart Disease. J Am Heart Assoc, 8(7), e010641. https://doi.org/10.1161/JAHA.118.010641
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  - Marquis-Gravel, G., Thiele, H., Jones, W. S., Smalling, R. W., Cohen, M., Perera, D., … Ohman, E. M. (2019). Size of Anterior Wall Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention in United States Versus Europe/Australia Versus India (from the CRISP-AMI Randomized Controlled Trial). Am J Cardiol, 123(7), 1026–1034. https://doi.org/10.1016/j.amjcard.2018.12.027
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  - Alenezi, F., Fudim, M., Rymer, J., Dunning, A., Chiswell, K., Swaminathan, M., … Samad, Z. (2019). Predictors and Changes in Cardiac Hemodynamics and Geometry With Transcatheter Aortic Valve Implantation. Am J Cardiol, 123(5), 813–819. https://doi.org/10.1016/j.amjcard.2018.11.038
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  - Kontos, M. C., Fordyce, C. B., Chen, A. Y., Chiswell, K., Enriquez, J. R., de Lemos, J., & Roe, M. T. (2019). Association of acute myocardial infarction cardiac arrest patient volume and in-hospital mortality in the United States: Insights from the National Cardiovascular Data Registry Acute Coronary Treatment And Intervention Outcomes Network Registry. Clin Cardiol, 42(3), 352–357. https://doi.org/10.1002/clc.23146
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  - Alenezi, F., Ambrosy, A. P., Phelan, M., Chiswell, K., Abudaqa, L., Alajmi, H., … Velazquez, E. J. (2019). Left Ventricular Global Longitudinal Strain Can Reliably Be Measured from a Single Apical Four-Chamber View in Patients with Heart Failure. J Am Soc Echocardiogr, 32(2), 317–318. https://doi.org/10.1016/j.echo.2018.10.009
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  - Held, C., White, H. D., Stewart, R. A. H., Davies, R., Sampson, S., Chiswell, K., … STABILITY Investigators, . (2019). Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial. Am Heart J, 208, 65–73. https://doi.org/10.1016/j.ahj.2018.10.010
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  - Fraser, C. D., Hill, K. D., Wallace, A., Chiswell, K., Zhou, X., Jelin, E. B., … Vricella, L. A. (2019). The Prevalence and Impact of Congenital Diaphragmatic Hernia Among Patients Undergoing Surgery for Congenital Heart Disease. Semin Thorac Cardiovasc Surg, 31(1), 69–77. https://doi.org/10.1053/j.semtcvs.2018.09.014
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  - Mahajan, A. M., Gandhi, H., Smilowitz, N. R., Roe, M. T., Hellkamp, A. S., Chiswell, K., … Reynolds, H. R. (2019). Seasonal and circadian patterns of myocardial infarction by coronary artery disease status and sex in the ACTION Registry-GWTG. Int J Cardiol, 274, 16–20. https://doi.org/10.1016/j.ijcard.2018.08.103
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  - Pagidipati, N. J., Mudrick, D. W., Chiswell, K., Brucker, A., Peterson, E. D., & Douglas, P. S. (2018). Sex differences in long-term outcomes of patients across the spectrum of coronary artery disease. Am Heart J, 206, 51–60. https://doi.org/10.1016/j.ahj.2018.09.014
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  - Kartha, V. M., Jacobs, J. P., Vener, D. F., Hill, K. D., Goldenberg, N. A., Pasquali, S. K., … Jacobs, M. L. (2018). National Benchmarks for Proportions of Patients Receiving Blood Transfusions During Pediatric and Congenital Heart Surgery: An Analysis of the STS Congenital Heart Surgery Database. Ann Thorac Surg, 106(4), 1197–1203. https://doi.org/10.1016/j.athoracsur.2018.04.088
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  - Holst, K. A., Dearani, J. A., Said, S. M., Davies, R. R., Pizarro, C., Knott-Craig, C., … Jacobs, M. L. (2018). Surgical Management and Outcomes of Ebstein Anomaly in Neonates and Infants: A Society of Thoracic Surgeons Congenital Heart Surgery Database Analysis. Ann Thorac Surg, 106(3), 785–791. https://doi.org/10.1016/j.athoracsur.2018.04.049
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  - Jacobs, M. L., Jacobs, J. P., Hill, K. D., O’Brien, S. M., Pasquali, S. K., Vener, D., … Fernandez, F. G. (2018). The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2018 Update on Research. Ann Thorac Surg, 106(3), 654–663. https://doi.org/10.1016/j.athoracsur.2018.06.032
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  - Siddiqui, I., Rajagopal, S., Brucker, A., Chiswell, K., Christopher, B., Alenezi, F., … Samad, Z. (2018). Clinical and Echocardiographic Predictors of Outcomes in Patients With Pulmonary Hypertension. Am J Cardiol, 122(5), 872–878. https://doi.org/10.1016/j.amjcard.2018.05.019
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  - Thaden, J. T., Chiswell, K., Jaffe, I., Bergin, S. P., Yang, W. E., Romaine, A., … Tsalik, E. L. (2018). Pediatric Antibacterial and Antifungal Trials From 2007 to 2017. Pediatrics, 142(3). https://doi.org/10.1542/peds.2017-1849
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  - Pagidipati, N. J., Clare, R. M., Keenan, R. T., Chiswell, K., Roe, M. T., & Hess, C. N. (2018). Association of Gout With Long-Term Cardiovascular Outcomes Among Patients With Obstructive Coronary Artery Disease. J Am Heart Assoc, 7(16), e009328. https://doi.org/10.1161/JAHA.118.009328
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  - Henry, T. D., Losordo, D. W., Traverse, J. H., Schatz, R. A., Jolicoeur, E. M., Schaer, G. L., … Povsic, T. J. (2018). Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials. Eur Heart J, 39(23), 2208–2216. https://doi.org/10.1093/eurheartj/ehx764
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  - Basra, S. S., Wang, T. Y., Simon, D. N., Chiswell, K., Virani, S. S., Alam, M., … Jneid, H. (2018). Ticagrelor Use in Acute Myocardial Infarction: Insights From the National Cardiovascular Data Registry. J Am Heart Assoc, 7(12). https://doi.org/10.1161/JAHA.117.008125
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  - Il’Giovine, Z. J., Mulder, H., Chiswell, K., Arges, K., Tomfohr, J., Hashmi, A., … Rajagopal, S. (2018). Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software. J Am Soc Echocardiogr, 31(6), 721-732.e5. https://doi.org/10.1016/j.echo.2018.01.008
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  - Green, J. L., Jacobs, A. K., Holmes, D., Chiswell, K., Blanco, R., Bates, E. R., … Nallamothu, B. K. (2018). Taking the Reins on Systems of Care for ST-Segment-Elevation Myocardial Infarction Patients: A Report From the American Heart Association Mission: Lifeline Program. Circ Cardiovasc Interv, 11(5), e005706. https://doi.org/10.1161/CIRCINTERVENTIONS.117.005706
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  - Sze, E., Samad, Z., Dunning, A., Campbell, K. B., Loring, Z., Atwater, B. D., … Daubert, J. P. (2018). Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block (vol 71, pg 306, 2018). Journal of the American College of Cardiology, 71(11), 1296–1296.
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  - Malta Hansen, C., Wang, T. Y., Chen, A. Y., Chiswell, K., Bhatt, D. L., Enriquez, J. R., … Roe, M. T. (2018). Contemporary Patterns of Early Coronary Angiography Use in Patients With Non-ST-Segment Elevation Myocardial Infarction in the United States: Insights From the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry. Jacc Cardiovasc Interv, 11(4), 369–380. https://doi.org/10.1016/j.jcin.2017.12.016
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  - Riley, I. L., Boulware, L. E., Sun, J.-L., Chiswell, K., Que, L. G., Kraft, M., … Anderson, M. L. (2018). Factors associated with reporting results for pulmonary clinical trials in ClinicalTrials.gov. Clin Trials, 15(1), 87–94. https://doi.org/10.1177/1740774517740352
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  - Sze, E., Samad, Z., Dunning, A., Campbell, K. B., Loring, Z., Atwater, B. D., … Daubert, J. P. (2018). Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block. J Am Coll Cardiol, 71(3), 306–317. https://doi.org/10.1016/j.jacc.2017.11.020
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  - Doll, J. A., Li, S., Chiswell, K., Roe, M. T., Kosiborod, M., Scirica, B. M., & Wang, T. Y. (2018). Clopidogrel reloading for patients with acute myocardial infarction already on clopidogrel therapy. Eur Heart J, 39(3), 193–200. https://doi.org/10.1093/eurheartj/ehx255
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  - Hagström, E., Norlund, F., Stebbins, A., Armstrong, P. W., Chiswell, K., Granger, C. B., … Held, C. (2018). Psychosocial stress and major cardiovascular events in patients with stable coronary heart disease. J Intern Med, 283(1), 83–92. https://doi.org/10.1111/joim.12692
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  - Mody, P., Wang, T., McNamara, R., Das, S., Li, S., Chiswell, K., … de Lemos, J. A. (2018). Association of acute kidney injury and chronic kidney disease with processes of care and long-term outcomes in patients with acute myocardial infarction. Eur Heart J Qual Care Clin Outcomes, 4(1), 43–50. https://doi.org/10.1093/ehjqcco/qcx020
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  - Krishnamoorthy, A., DeVore, A. D., Sun, J.-L., Barnett, A. S., Samsky, M. D., Shaw, L. K., … Patel, M. R. (2017). The impact of a failing right heart in patients supported by intra-aortic balloon counterpulsation. Eur Heart J Acute Cardiovasc Care, 6(8), 709–718. https://doi.org/10.1177/2048872616652262
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  - Smilowitz, N. R., Mahajan, A. M., Roe, M. T., Hellkamp, A. S., Chiswell, K., Gulati, M., & Reynolds, H. R. (2017). Mortality of Myocardial Infarction by Sex, Age, and Obstructive Coronary Artery Disease Status in the ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines). Circ Cardiovasc Qual Outcomes, 10(12), e003443. https://doi.org/10.1161/CIRCOUTCOMES.116.003443
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  - Sze, E., Dunning, A., Loring, Z., Atwater, B. D., Chiswell, K., Daubert, J. P., … Samad, Z. (2017). Comparison of Incidence of Left Ventricular Systolic Dysfunction Among Patients With Left Bundle Branch Block Versus Those With Normal QRS Duration. Am J Cardiol, 120(11), 1990–1997. https://doi.org/10.1016/j.amjcard.2017.08.003
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  - Kragholm, K., Lu, D., Chiswell, K., Al-Khalidi, H. R., Roettig, M. L., Roe, M., … Granger, C. B. (2017). Improvement in Care and Outcomes for Emergency Medical Service-Transported Patients With ST-Elevation Myocardial Infarction (STEMI) With and Without Prehospital Cardiac Arrest: A Mission: Lifeline STEMI Accelerator Study. J Am Heart Assoc, 6(10). https://doi.org/10.1161/JAHA.117.005717
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  - Vidal-Petiot, E., Stebbins, A., Chiswell, K., Ardissino, D., Aylward, P. E., Cannon, C. P., … STABILITY Investigators, . (2017). Visit-to-visit variability of blood pressure and cardiovascular outcomes in patients with stable coronary heart disease. Insights from the STABILITY trial. European Heart Journal, 38(37), 2813–2822. https://doi.org/10.1093/eurheartj/ehx250
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  - Badri, M., Abdelbaky, A., Li, S., Chiswell, K., & Wang, T. Y. (2017). Precatheterization Use of P2Y12 Inhibitors in Non-ST-Elevation Myocardial Infarction Patients Undergoing Early Cardiac Catheterization and In-Hospital Coronary Artery Bypass Grafting: Insights From the National Cardiovascular Data Registry®. J Am Heart Assoc, 6(9). https://doi.org/10.1161/JAHA.117.006508
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  - Guimarães, P. O., Granger, C. B., Stebbins, A., Chiswell, K., Held, C., Hochman, J. S., … Danchin, N. (2017). Sex Differences in Clinical Characteristics, Psychosocial Factors, and Outcomes Among Patients With Stable Coronary Heart Disease: Insights from the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial. J Am Heart Assoc, 6(9). https://doi.org/10.1161/JAHA.117.006695
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  - Vora, A. N., Wang, T. Y., Li, S., Chiswell, K., Hess, C., Lopes, R. D., … Peterson, E. D. (2017). Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines. J Am Heart Assoc, 6(8). https://doi.org/10.1161/JAHA.116.005280
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  - Pi, Y., Roe, M. T., Holmes, D. N., Chiswell, K., Garvey, J. L., Fonarow, G. C., … Xian, Y. (2017). Utilization, Characteristics, and In-Hospital Outcomes of Coronary Artery Bypass Grafting in Patients With ST-Segment-Elevation Myocardial Infarction: Results From the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines. Circ Cardiovasc Qual Outcomes, 10(8). https://doi.org/10.1161/CIRCOUTCOMES.116.003490
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  - Pandey, A., Golwala, H., Hall, H. M., Wang, T. Y., Lu, D., Xian, Y., … de Lemos, J. A. (2017). Association of US Centers for Medicare and Medicaid Services Hospital 30-Day Risk-Standardized Readmission Metric With Care Quality and Outcomes After Acute Myocardial Infarction: Findings From the National Cardiovascular Data Registry/Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines. Jama Cardiol, 2(7), 723–731. https://doi.org/10.1001/jamacardio.2017.1143
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  - Banks, A., Broderick, S., Chiswell, K., Shaw, L., Devore, A., Fiuzat, M., … Mentz, R. (2017). Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease). Am J Cardiol, 119(11), 1703–1709. https://doi.org/10.1016/j.amjcard.2017.02.053
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  - Randolph, T. C., Broderick, S., Shaw, L. K., Chiswell, K., Mentz, R. J., Kutyifa, V., … Thomas, K. L. (2017). Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction. J Am Heart Assoc, 6(3). https://doi.org/10.1161/JAHA.116.004381
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  - Roswell, R. O., Kunkes, J., Chen, A. Y., Chiswell, K., Iqbal, S., Roe, M. T., & Bangalore, S. (2017). Impact of Sex and Contact-to-Device Time on Clinical Outcomes in Acute ST-Segment Elevation Myocardial Infarction-Findings From the National Cardiovascular Data Registry. Journal of the American Heart Association, 6(1), e004521. https://doi.org/10.1161/jaha.116.004521
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  - Shah, R., Clare, R. M., Chiswell, K., Jones, W. S., Kumar, A. S., Thiele, H., … Patel, M. R. (2016). Impact of Non-Infarct-Related Artery Disease on Infarct Size and Outcomes (from the CRISP-AMI Trial). Am J Med, 129(12), 1307–1315. https://doi.org/10.1016/j.amjmed.2016.07.011
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  - Douglas, P. S., De Bruyne, B., Pontone, G., Patel, M. R., Norgaard, B. L., Byrne, R. A., … PLATFORM Investigators, . (2016). 1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease: The PLATFORM Study. J Am Coll Cardiol, 68(5), 435–445. https://doi.org/10.1016/j.jacc.2016.05.057
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  - Stewart, R. A. H., Wallentin, L., Benatar, J., Danchin, N., Hagström, E., Held, C., … STABILITY Investigators, . (2016). Dietary patterns and the risk of major adverse cardiovascular events in a global study of high-risk patients with stable coronary heart disease. European Heart Journal, 37(25), 1993–2001. https://doi.org/10.1093/eurheartj/ehw125
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  - Kohl, L. P., Leimberger, J. D., Chiswell, K., Jones, W. S., Thiele, H., Smalling, R. W., … Patel, M. R. (2016). Clinical characteristics and outcomes after unplanned intraaortic balloon counterpulsation in the Counterpulsation to Reduce Infarct Size Pre-PCI Acute Myocardial Infarction trial. Am Heart J, 174, 7–13. https://doi.org/10.1016/j.ahj.2015.12.004
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  - Barnard, K., Lakey, W. C., Batch, B. C., Chiswell, K., Tasneem, A., & Green, J. B. (2016). Recent Clinical Trials in Osteoporosis: A Firm Foundation or Falling Short? Plos One, 11(5), e0156068. https://doi.org/10.1371/journal.pone.0156068
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  - Douglas, P. S., Pontone, G., Hlatky, M. A., Patel, M. R., Norgaard, B. L., Byrne, R. A., … PLATFORM Investigators, . (2015). Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR(CT): outcome and resource impacts study. Eur Heart J, 36(47), 3359–3367. https://doi.org/10.1093/eurheartj/ehv444
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  - Ruopp, M., Chiswell, K., Thaden, J. T., Merchant, K., & Tsalik, E. L. (2015). Respiratory Tract Infection Clinical Trials from 2007 to 2012. A Systematic Review of ClinicalTrials.gov. Ann Am Thorac Soc, 12(12), 1852–1863. https://doi.org/10.1513/AnnalsATS.201505-291OC
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  - Mentz, R. J., Velazquez, E. J., Metra, M., McKendry, C., Chiswell, K., Fiuzat, M., … O’Connor, C. M. (2015). Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial. Future Cardiol, 11(5), 585–595. https://doi.org/10.2217/fca.15.56
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  - Pontone, G., Patel, M. R., Hlatky, M. A., Chiswell, K., Andreini, D., Norgaard, B. L., … Douglas, P. S. (2015). Rationale and design of the Prospective LongitudinAl Trial of FFRCT: Outcome and Resource IMpacts study. Am Heart J, 170(3), 438-46.e44. https://doi.org/10.1016/j.ahj.2015.06.002
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  - Hess, C. N., Roe, M. T., Clare, R. M., Chiswell, K., Kelly, J., Tcheng, J. E., … Krucoff, M. W. (2015). Relationship Between Cancer and Cardiovascular Outcomes Following Percutaneous Coronary Intervention. J Am Heart Assoc, 4(7). https://doi.org/10.1161/JAHA.115.001779
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  - Mentz, R. J., Metra, M., Cotter, G., Milo, O., McKendry, C., Chiswell, K., … O’Connor, C. M. (2015). Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial. Eur J Heart Fail, 17(7), 697–706. https://doi.org/10.1002/ejhf.308
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  - Holmqvist, F., Thomas, K. L., Broderick, S., Ersbøll, M., Singh, D., Chiswell, K., … Daubert, J. P. (2015). Clinical outcome as a function of the PR-interval-there is virtue in moderation: data from the Duke Databank for cardiovascular disease. Europace, 17(6), 978–985. https://doi.org/10.1093/europace/euu211
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  - Subherwal, S., Patel, M. R., & Chiswell, K. (2015). Clinical trials in peripheral vascular disease pipeline and trial designs: An evaluation of the clinical trials.gov database. Journal of Vascular Surgery, 61(4), 1099. https://doi.org/10.1016/j.jvs.2015.03.005
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  - Anderson, M. L., Chiswell, K., Peterson, E. D., Tasneem, A., Topping, J., & Califf, R. M. (2015). Compliance with results reporting at ClinicalTrials.gov. N Engl J Med, 372(11), 1031–1039. https://doi.org/10.1056/NEJMsa1409364
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  - Jones, W. S., Clare, R. M., Chiswell, K., Perera, D., French, J. K., Kumar, A. S., … Patel, M. R. (2015). The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial. Clin Cardiol, 38(1), 25–31. https://doi.org/10.1002/clc.22349
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  - Metra, M., Mentz, R. J., Chiswell, K., Bloomfield, D. M., Cleland, J. G. F., Cotter, G., … O’Connor, C. M. (2015). Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. Eur J Heart Fail, 17(1), 109–118. https://doi.org/10.1002/ejhf.207
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  - Mentz, R. J., Broderick, S., Shaw, L. K., Chiswell, K., Fiuzat, M., & O’Connor, C. M. (2014). Persistent angina pectoris in ischaemic cardiomyopathy: increased rehospitalization and major adverse cardiac events. Eur J Heart Fail, 16(8), 854–860. https://doi.org/10.1002/ejhf.130
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  - Hill, K. D., Chiswell, K., Califf, R. M., Pearson, G., & Li, J. S. (2014). Characteristics of pediatric cardiovascular clinical trials registered on ClinicalTrials.gov. Am Heart J, 167(6), 921-9.e2. https://doi.org/10.1016/j.ahj.2014.02.002
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  - Mentz, R. J., Cotter, G., Cleland, J. G. F., Stevens, S. R., Chiswell, K., Davison, B. A., … O’Connor, C. M. (2014). International differences in clinical characteristics, management, and outcomes in acute heart failure patients: better short-term outcomes in patients enrolled in Eastern Europe and Russia in the PROTECT trial. Eur J Heart Fail, 16(6), 614–624. https://doi.org/10.1002/ejhf.92
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  - Inrig, J. K., Califf, R. M., Tasneem, A., Vegunta, R. K., Molina, C., Stanifer, J. W., … Patel, U. D. (2014). The landscape of clinical trials in nephrology: a systematic review of Clinicaltrials.gov. Am J Kidney Dis, 63(5), 771–780. https://doi.org/10.1053/j.ajkd.2013.10.043
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  - Cleland, J. G., Chiswell, K., Teerlink, J. R., Stevens, S., Fiuzat, M., Givertz, M. M., … O’Connor, C. M. (2014). Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function (PROTECT) Study. Circ Heart Fail, 7(1), 76–87. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000284
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  - Witsell, D. L., Schulz, K. A., Lee, W. T., & Chiswell, K. (2013). An analysis of registered clinical trials in otolaryngology from 2007 to 2010: ClinicalTrials.gov. Otolaryngol Head Neck Surg, 149(5), 692–699. https://doi.org/10.1177/0194599813506545
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  - Todd, J. L., White, K. R., Chiswell, K., Tasneem, A., & Palmer, S. M. (2013). Using ClinicalTrials.gov to understand the state of clinical research in pulmonary, critical care, and sleep medicine. Ann Am Thorac Soc, 10(5), 411–417. https://doi.org/10.1513/AnnalsATS.201305-111OC
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  - Alexander, K. P., Kong, D. F., Starr, A. Z., Kramer, J., Chiswell, K., Tasneem, A., & Califf, R. M. (2013). Portfolio of clinical research in adult cardiovascular disease as reflected in ClinicalTrials.gov. J Am Heart Assoc, 2(5), e000009. https://doi.org/10.1161/JAHA.113.000009
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  - Vavalle, J. P., Clare, R., Chiswell, K., Rao, S. V., Petersen, J. L., Kleiman, N. S., … Wang, T. Y. (2013). Prognostic significance of bleeding location and severity among patients with acute coronary syndromes. Jacc Cardiovasc Interv, 6(7), 709–717. https://doi.org/10.1016/j.jcin.2013.03.010
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  - Hirsch, B. R., Califf, R. M., Cheng, S. K., Tasneem, A., Horton, J., Chiswell, K., … Abernethy, A. P. (2013). Characteristics of oncology clinical trials: insights from a systematic analysis of ClinicalTrials.gov. Jama Intern Med, 173(11), 972–979. https://doi.org/10.1001/jamainternmed.2013.627
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  - Lakey, W. C., Barnard, K., Batch, B. C., Chiswell, K., Tasneem, A., & Green, J. B. (2013). Are current clinical trials in diabetes addressing important issues in diabetes care? Diabetologia, 56(6), 1226–1235. https://doi.org/10.1007/s00125-013-2890-4
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  - Rose, J. J., Newby, L. K., Broderick, S., Chiswell, K., Van de Werf, F., Armstrong, P. W., … Lopes, R. D. (2013). Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes. J Am Coll Cardiol, 61(13), 1461–1463. https://doi.org/10.1016/j.jacc.2012.12.032
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  - Berger, P. B., Williams, J. B., Hasselblad, V., Chiswell, K., Pieper, K. S., & Califf, R. M. (2013). Would tirofiban have been shown non-inferior to abciximab had the TENACITY trial not been terminated for financial reasons? J Interv Cardiol, 26(2), 123–130. https://doi.org/10.1111/j.1540-8183.2013.12020.x
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  - Mentz, R. J., Wojdyla, D., Fiuzat, M., Chiswell, K., Fonarow, G. C., & O’Connor, C. M. (2013). Association of beta-blocker use and selectivity with outcomes in patients with heart failure and chronic obstructive pulmonary disease (from OPTIMIZE-HF). Am J Cardiol, 111(4), 582–587. https://doi.org/10.1016/j.amjcard.2012.10.041
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  - Goswami, N. D., Pfeiffer, C. D., Horton, J. R., Chiswell, K., Tasneem, A., & Tsalik, E. L. (2013). The state of infectious diseases clinical trials: a systematic review of ClinicalTrials.gov. Plos One, 8(10), e77086. https://doi.org/10.1371/journal.pone.0077086
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  - Williams, E. S., Thompson, V. P., Chiswell, K. E., Alexander, J. H., White, H. D., Ohman, E. M., & Al-Khatib, S. M. (2013). Rate versus rhythm control and outcomes in patients with atrial fibrillation and chronic kidney disease: data from the GUSTO-III Trial. Cardiol J, 20(4), 439–446. https://doi.org/10.5603/CJ.2013.0104
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  - Pasquali, S. K., Lam, W. K., Chiswell, K., Kemper, A. R., & Li, J. S. (2012). Status of the pediatric clinical trials enterprise: an analysis of the US ClinicalTrials.gov registry. Pediatrics, 130(5), e1269–e1277. https://doi.org/10.1542/peds.2011-3565
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  - Green, J. B., Lakey, W., Barnard, K., Batch, B., Bethel, M., Chiswell, K., & Tasneem, A. (2012). State of diabetes-related trials in the clinicaltrials.gov dataset. Diabetologia, 55, S90–S91.
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  - Thomas, M. P., Mahaffey, K. W., Chiswell, K., Cohen, M., Kontos, M. C., Antman, E. M., … Becker, R. C. (2012). Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin. J Thromb Thrombolysis, 34(1), 114–119. https://doi.org/10.1007/s11239-012-0693-y
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  - O’Connor, C. M., Mentz, R. J., Cotter, G., Metra, M., Cleland, J. G., Davison, B. A., … Massie, B. M. (2012). The PROTECT in-hospital risk model: 7-day outcome in patients hospitalized with acute heart failure and renal dysfunction. Eur J Heart Fail, 14(6), 605–612. https://doi.org/10.1093/eurjhf/hfs029
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  - Mentz, R. J., Fiuzat, M., Wojdyla, D. M., Chiswell, K., Gheorghiade, M., Fonarow, G. C., & O’Connor, C. M. (2012). Clinical characteristics and outcomes of hospitalized heart failure patients with systolic dysfunction and chronic obstructive pulmonary disease: findings from OPTIMIZE-HF. Eur J Heart Fail, 14(4), 395–403. https://doi.org/10.1093/eurjhf/hfs009
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  - Novick, S., Chiswell, K., & Peterson, J. (2012). A Bayesian Approach to Show Assay Equivalence with Replicate Measurements Over a Specified Response Range. Statistics in Biopharmaceutical Research, 4(2), 102–117. https://doi.org/10.1198/sbr.2010.09049
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  - Tasneem, A., Aberle, L., Ananth, H., Chakraborty, S., Chiswell, K., McCourt, B. J., & Pietrobon, R. (2012). The database for aggregate analysis of ClinicalTrials.gov (AACT) and subsequent regrouping by clinical specialty. Plos One, 7(3), e33677. https://doi.org/10.1371/journal.pone.0033677
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  - Hirsch, B. R., Califf, R. M., Tasneem, A., Chiswell, K., Bolte, J., Schulman, K. A., & Abernethy, A. P. (2011). Assessment of clinical trials in oncology: An evaluation of 40,696 trials on ClinicalTrials.gov. J Clin Oncol, 29(15_suppl), 6095.
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  - Goffinet, C., Allespach, I., Oberbremer, L., Golden, P. L., Foster, S. A., Johns, B. A., … Keppler, O. T. (2009). Pharmacovirological impact of an integrase inhibitor on human immunodeficiency virus type 1 cDNA species in vivo. Journal of Virology, 83(15), 7706–7717. https://doi.org/10.1128/jvi.00683-09
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  - Muniz-Medina, V. M., Jones, S., Maglich, J. M., Galardi, C., Hollingsworth, R. E., Kazmierski, W. M., … Kenakin, T. P. (2009). The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property? Molecular Pharmacology, 75(3), 490–501. https://doi.org/10.1124/mol.108.052555
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  - Rao, S. V., Chiswell, K., Sun, J.-L., Granger, C. B., Newby, L. K., Van de Werf, F., … Harrington, R. A. (2008). International variation in the use of blood transfusion in patients with non-ST-segment elevation acute coronary syndromes. Am J Cardiol, 101(1), 25–29. https://doi.org/10.1016/j.amjcard.2007.07.042
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  - Fonarow, G. C., Lukas, M. A., Robertson, M., Colucci, W. S., & Dargie, H. J. (2007). Effects of carvedilol early after myocardial infarction: Analysis of the first 30 days in Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN). American Heart Journal, 154(4), 637–644. https://doi.org/10.1016/j.ahj.2007.06.002
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  - Greenberg, B. H., Abraham, W. T., Albert, N. M., Chiswell, K., Clare, R., Stough, W. G., … Fonarow, G. C. (2007). Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: A report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). American Heart Journal, 154(4), 647–654. https://doi.org/10.1016/j.ahj.2007.08.002
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  - Greenberg, B. H., Abraham, W. T., Albert, N. M., Chiswell, K., Clare, R., Stough, W. G., … Fonarow, G. C. (2007). Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: a report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Am Heart J, 154(2), 277.e1-277.e8. https://doi.org/10.1016/j.ahj.2007.05.001
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  - Albert, N. M., Fonarow, G. C., Abraham, W. T., Chiswell, K., Stough, W. G., Gheorghiade, M., … Young, J. B. (2007). Predictors of delivery of hospital-based heart failure patient education: a report from OPTIMIZE-HF. J Card Fail, 13(3), 189–198. https://doi.org/10.1016/j.cardfail.2006.11.008
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  - White, H. D., Kleiman, N. S., Mahaffey, K. W., Lokhnygina, Y., Pieper, K. S., Chiswell, K., … Califf, R. M. (2006). Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial. Am Heart J, 152(6), 1042–1050. https://doi.org/10.1016/j.ahj.2006.08.002
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  - Chandler, R. E., Chiswell, K. E., & Faulkner, G. D. (2006). Quantifying a possible miocene phyletic change in Hemipristis (Chondrichthyes) teeth. Palaeontologia Electronica, 9(1).
  - Viero, P. W. M., Chiswell, K. E. A., & Theron, J. M. (2002). The effect of a soil-amended hydrogel on the establishment of a eucalyptus grandis clone on a sandy clay loam soil in zululand during winter. Southern African Forestry Journal, 193(1), 65–75. https://doi.org/10.1080/20702620.2002.10433519
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- Conference Papers
  - Carnicelli, A. P., Clare, R., Hofmann, P., Chiswell, K., DeVore, A. D., Vemulapalli, S., … Mentz, R. J. (2021). Characteristics and Outcomes of Patients With Heart Failure With Reduced Ejection Fraction After a Recent Worsening Heart Failure Event. In J Am Heart Assoc (Vol. 10, p. e021276). England. https://doi.org/10.1161/JAHA.120.021276
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  - Serfas, J. D., Thibault, D., Andersen, N. D., Chiswell, K., Jacobs, J. P., Jacobs, M. L., … Hill, K. D. (2021). The Evolving Surgical Burden of Fontan Failure: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database. In Annals of Thoracic Surgery (Vol. 112, pp. 179–187). https://doi.org/10.1016/j.athoracsur.2020.05.174
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  - Chew, J., Hill, K., Soslow, J., Jacobs, M., Jacobs, J., Eghtesady, P., … Godown, J. (2021). CONTEMPORARY PRACTICE IN SURGICAL MANAGEMENT OF CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES:AN ANALYSIS THE SOCIETYOF THORACIC SURGEONS CONGENITAL HEART SURGERY DATABASE(STS-CHD). In Journal of the American College of Cardiology (Vol. 77, pp. 499–499).
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  - Kelsey, M. D., Mulder, H., Chiswell, K., Lampron, Z. M., Nilles, E. K. K., Kulinski, J. P., … Pagidipati, N. J. (2021). Contemporary Patterns of Lipoprotein(a) Testing and Associated Clinical Care and Outcomes. In Circulation (Vol. 144).
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  - Vaduganathan, M., Greene, S. J., Patel, R. B., Zhang, S., Chiswell, K., Devore, A. D., … Kittleson, M. M. (2021). Incident Dialysis and Acute Kidney Injury Among Medicare Beneficiaries After Hospitalization for Heart Failure in the US. In Circulation (Vol. 144).
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  - Swaminathan, A. C., Li, J., Chiswell, K., McManigle, W., O’Doherty, I., Fitzsimmons, W., … Palmer, S. M. (2020). The State of Interventional Clinical Trials in Solid Organ Transplant: Insights from a Systematic Analysis of Clinicaltrials.gov. In American Journal of Transplantation (Vol. 20, pp. 598–598).
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  - Goodman, S. G., Mahaffey, K. W., Chiswell, K., Cohen, M., Kontos, M. C., Antman, E. M., … Becker, R. (2007). Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin. In Journal of the American College of Cardiology (Vol. 49, pp. 186A-186A). New Orleans, LA: ELSEVIER SCIENCE INC.
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  - Albert, N. M., Fonarow, G., Abraham, W., Chiswell, K., Stough, W. G., Gheorghiade, M., … Young, J. (2006). Do hospitals that provide heart failure patient education prior to discharge also promote continuity of care? A report from OPTIMIZE-HF. In Journal of Cardiac Failure (Vol. 12, pp. S112–S112). Seattle, WA: CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS.
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  - Abraham, W. T., Greenberg, B., Fonarow, G. C., Albert, N. M., Chiswell, K., Stough, W. G., … Young, J. B. (2006). Cardiac resynchronization device placement during hospitalization for heart failure is associated with a significant improvement in early clinical outcomes. In Journal of the American College of Cardiology (Vol. 47, pp. 19A-19A). Atlanta, GA: ELSEVIER SCIENCE INC.
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  - Albert, N. M., Fonarow, G. C., Abraham, W. T., Chiswell, K., Stough, W. G., Gheorghiade, M., … Young, J. B. (2006). Do hospitals that provide heart failure patient education prior to discharge also promote continuity of care? - A report from OPTIMIZE-HF. In Journal of the American College of Cardiology (Vol. 47, pp. 267A-268A). Atlanta, GA: ELSEVIER SCIENCE INC.
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  - Ferrarow, G. C., Abraham, W. T., Albert, N. M., Chiswell, K., Stough, W. G., Gheorghiade, M., … Young, J. B. (2006). ACC/AHA performance measures for patients hospitalized with HF: Are they predictive of clinical outcomes? In Journal of the American College of Cardiology (Vol. 47, pp. 255A-255A). Atlanta, GA: ELSEVIER SCIENCE INC.
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  - Levine, G. N., Lokhnygina, Y., White, H. D., Chiswell, K., Kleiman, N. S., Mahaffey, K. W., … Califf, R. M. (2006). Percutaneous coronary intervention in patients receiving only a single subcutaneous dose of enoxaparin: Results from the SYNERGY trial. In Journal of the American College of Cardiology (Vol. 47, pp. 228A-228A). Atlanta, GA: ELSEVIER SCIENCE INC.
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  - Moser, D., Chiswell, K., Yamokoski, L., Conway, G., Hartman, K. A., Binanay, C., & Stevenson, L. W. (2005). Lack of improvement in quality of life post-hospitalization predicts mortality in patients with advanced heart failure. In Journal of the American College of Cardiology (Vol. 45, pp. 178A-178A). Orlando, FL: ELSEVIER SCIENCE INC.
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