Overview
Ph.D., North Carolina State University - 2007
I work closely with clinical and quantitative colleagues to provide statistical leadership, guidance and mentoring on the design, execution, and analysis of clinical research studies. My work includes design and analysis of observational studies (including large cardiovascular registries, and clinical care databases linked with electronic health record data) and early-phase trials in pediatric populations. My statistical interests include study design, linear and non-linear mixed effects models, survival analysis, biology- and mechanism-based models, and statistical thinking and learning.
Current Appointments & Affiliations
Statistical Scientist
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Clinical Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors Among Older Patients Hospitalized for Heart Failure With Reduced Ejection Fraction.
Journal Article J Am Heart Assoc · May 19, 2026 BACKGROUND: SGLT2 (sodium-glucose cotransporter-2) inhibitors (SGLT2i) reduce cardiovascular events in randomized controlled trials of patients with heart failure with reduced ejection fraction (HFrEF), but these trials enrolled outpatient, relatively youn ... Full text Link to item CitePredictors of ischemic stroke and major bleeding among patients with atrial fibrillation in clinical practice.
Journal Article Am Heart J · May 19, 2026 BACKGROUND: Numerous risk scores exist to quantify the risk of ischemic stroke risk in patients with atrial fibrillation or flutter (AF/AFL). However, how these tools perform in cohorts or those already on oral anticoagulation (OAC) therapy is unclear. MET ... Full text Link to item CiteTrends in the Evaluation of Acute Chest Pain: An Analysis of the Chest Pain-MI National Cardiovascular Data Registry.
Conference JACC. Cardiovascular imaging · May 2026 Full text CiteRecent Grants
The North Carolina Congenital Heart Disease Surveillance Network
Public ServiceSenior Statistician · Awarded by Centers for Disease Control and Prevention · 2024 - 2029Increasing the Quality and Efficiency of Clinical Trials (U18)
ResearchStatistician · Awarded by Food and Drug Administration · 2014 - 2029Pharmacokinetic and pharmacodynamic study of montelukast in premature infants with BPD (PRISM)
ResearchStatistical Investigator · Awarded by National Institutes of Health · 2023 - 2028View All Grants