Karen Chiswell | Scholars@Duke

Karen Chiswell
Statistical Scientist

Ph.D., North Carolina State University - 2007

I work closely with clinical and quantitative colleagues to provide statistical leadership, guidance and mentoring on the design, execution, and analysis of clinical research studies. My work includes design and analysis of observational studies (including large cardiovascular registries, and clinical care databases linked with electronic health record data) and early-phase trials in pediatric populations. My statistical interests include study design, linear and non-linear mixed effects models, survival analysis, biology- and mechanism-based models, and statistical thinking and learning.

Current Appointments & Affiliations

Statistical Scientist, Duke Clinical Research Institute, Institutes and Centers

Contact Information

200 Morris Street, #5510, Durham, NC 27701
karen.chiswell@duke.edu +1 919 668 8395

Expertise
Subject Headings
Research
Selected Grants
- The North Carolina Congenital Heart Disease Surveillance Network 2019 - 2024
- Increasing the Quality and Efficiency of Clinical Trials (U18) awarded by Food and Drug Administration 2014 - 2024
- Pathways to cardiovascular disease prevention and impact of specialty referral in under-represented racial/ethnic minorities with HIV awarded by National Institutes of Health 2018 - 2023
- North Carolina Congenital Heart Defects Surveillance Network 2015 - 2020
- Using AACT - to answer Oncology landscape portfolio of open trials 2017 - 2018
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Chew, Joshua D., Kevin D. Hill, Marshall L. Jacobs, Jeffrey P. Jacobs, Stacy A. S. Killen, Justin Godown, Amelia S. Wallace, et al. “Congenital Heart Surgery Outcomes in Turner Syndrome: The Society of Thoracic Surgeons Database Analysis..” Ann Thorac Surg 108, no. 5 (November 2019): 1430–37. https://doi.org/10.1016/j.athoracsur.2019.05.047.
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  - Shelburne, Nicholas J., Kishan S. Parikh, Karen Chiswell, Linda K. Shaw, Joseph Sivak, Kristine Arges, Jennifer Tomfohr, et al. “Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension..” Am J Cardiol 124, no. 8 (October 15, 2019): 1298–1304. https://doi.org/10.1016/j.amjcard.2019.07.026.
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  - Jacobs, Marshall L., Jeffrey P. Jacobs, Kevin D. Hill, Sean M. O’Brien, Sara K. Pasquali, David Vener, S Ram Kumar, et al. “The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2019 Update on Research..” Ann Thorac Surg 108, no. 3 (September 2019): 671–79. https://doi.org/10.1016/j.athoracsur.2019.07.002.
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  - Sullivan, Lonnie T., Hillary Mulder, Karen Chiswell, Linda K. Shaw, Tracy Y. Wang, Larry R. Jackson, and Kevin L. Thomas. “Racial differences in long-term outcomes among black and white patients with drug-eluting stents..” Am Heart J 214 (August 2019): 46–53. https://doi.org/10.1016/j.ahj.2019.04.005.
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  - Jaffe, Ian S., Karen Chiswell, and Ephraim L. Tsalik. “A Decade On: Systematic Review of ClinicalTrials.gov Infectious Disease Trials, 2007-2017..” Open Forum Infect Dis 6, no. 6 (June 2019). https://doi.org/10.1093/ofid/ofz189.
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  - Kogon, Brian E., Matthew E. Oster, Amelia Wallace, Karen Chiswell, Kevin D. Hill, Morgan L. Cox, Jeffrey P. Jacobs, Sara Pasquali, Tara Karamlou, and Marshall L. Jacobs. “Readmission After Pediatric Cardiothoracic Surgery: An Analysis of The Society of Thoracic Surgeons Database..” Ann Thorac Surg 107, no. 6 (June 2019): 1816–23. https://doi.org/10.1016/j.athoracsur.2019.01.009.
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  - Stewart, Ralph A. H., Claes Held, Sue Krug-Gourley, Dawn Waterworth, Amanda Stebbins, Karen Chiswell, Emil Hagstrom, Paul W. Armstrong, Lars Wallentin, and Harvey White. “Cardiovascular and Lifestyle Risk Factors and Cognitive Function in Patients With Stable Coronary Heart Disease..” J Am Heart Assoc 8, no. 7 (April 2, 2019). https://doi.org/10.1161/JAHA.118.010641.
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  - Marquis-Gravel, Guillaume, Holger Thiele, W Schuyler Jones, Richard W. Smalling, Marc Cohen, Divaka Perera, Nico Pijls, et al. “Size of Anterior Wall Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention in United States Versus Europe/Australia Versus India (from the CRISP-AMI Randomized Controlled Trial)..” Am J Cardiol 123, no. 7 (April 1, 2019): 1026–34. https://doi.org/10.1016/j.amjcard.2018.12.027.
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  - Alenezi, Fawaz, Marat Fudim, Jennifer Rymer, Allison Dunning, Karen Chiswell, Madhav Swaminathan, Brandi Bottiger, et al. “Predictors and Changes in Cardiac Hemodynamics and Geometry With Transcatheter Aortic Valve Implantation..” Am J Cardiol 123, no. 5 (March 1, 2019): 813–19. https://doi.org/10.1016/j.amjcard.2018.11.038.
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  - Kontos, Michael C., Christopher B. Fordyce, Anita Y. Chen, Karen Chiswell, Jonathan R. Enriquez, James de Lemos, and Matthew T. Roe. “Association of acute myocardial infarction cardiac arrest patient volume and in-hospital mortality in the United States: Insights from the National Cardiovascular Data Registry Acute Coronary Treatment And Intervention Outcomes Network Registry..” Clin Cardiol 42, no. 3 (March 2019): 352–57. https://doi.org/10.1002/clc.23146.
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  - Alenezi, Fawaz, Andrew P. Ambrosy, Matthew Phelan, Karen Chiswell, Loai Abudaqa, Hasan Alajmi, Joseph Kisslo, and Eric J. Velazquez. “Left Ventricular Global Longitudinal Strain Can Reliably Be Measured from a Single Apical Four-Chamber View in Patients with Heart Failure..” J Am Soc Echocardiogr 32, no. 2 (February 2019): 317–18. https://doi.org/10.1016/j.echo.2018.10.009.
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  - Held, Claes, Harvey D. White, Ralph A. H. Stewart, Richard Davies, Shani Sampson, Karen Chiswell, Adam Silverstein, et al. “Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial..” Am Heart J 208 (February 2019): 65–73. https://doi.org/10.1016/j.ahj.2018.10.010.
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  - Fraser, Charles D., Kevin D. Hill, Amelia Wallace, Karen Chiswell, Xun Zhou, Eric B. Jelin, David Kays, et al. “The Prevalence and Impact of Congenital Diaphragmatic Hernia Among Patients Undergoing Surgery for Congenital Heart Disease..” Semin Thorac Cardiovasc Surg 31, no. 1 (2019): 69–77. https://doi.org/10.1053/j.semtcvs.2018.09.014.
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  - Mahajan, Asha M., Himali Gandhi, Nathaniel R. Smilowitz, Matthew T. Roe, Anne S. Hellkamp, Karen Chiswell, Martha Gulati, and Harmony R. Reynolds. “Seasonal and circadian patterns of myocardial infarction by coronary artery disease status and sex in the ACTION Registry-GWTG..” Int J Cardiol 274 (January 1, 2019): 16–20. https://doi.org/10.1016/j.ijcard.2018.08.103.
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  - Pagidipati, Neha J., Daniel W. Mudrick, Karen Chiswell, Amanda Brucker, Eric D. Peterson, and Pamela S. Douglas. “Sex differences in long-term outcomes of patients across the spectrum of coronary artery disease..” Am Heart J 206 (December 2018): 51–60. https://doi.org/10.1016/j.ahj.2018.09.014.
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  - Kartha, Vyas M., Jeffrey P. Jacobs, David F. Vener, Kevin D. Hill, Neil A. Goldenberg, Sara K. Pasquali, James M. Meza, et al. “National Benchmarks for Proportions of Patients Receiving Blood Transfusions During Pediatric and Congenital Heart Surgery: An Analysis of the STS Congenital Heart Surgery Database..” Ann Thorac Surg 106, no. 4 (October 2018): 1197–1203. https://doi.org/10.1016/j.athoracsur.2018.04.088.
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  - Holst, Kimberly A., Joseph A. Dearani, Sameh M. Said, Ryan R. Davies, Christian Pizarro, Christopher Knott-Craig, TK Susheel Kumar, et al. “Surgical Management and Outcomes of Ebstein Anomaly in Neonates and Infants: A Society of Thoracic Surgeons Congenital Heart Surgery Database Analysis..” Ann Thorac Surg 106, no. 3 (September 2018): 785–91. https://doi.org/10.1016/j.athoracsur.2018.04.049.
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  - Jacobs, Marshall L., Jeffrey P. Jacobs, Kevin D. Hill, Sean M. O’Brien, Sara K. Pasquali, David Vener, S Ram Kumar, et al. “The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2018 Update on Research..” Ann Thorac Surg 106, no. 3 (September 2018): 654–63. https://doi.org/10.1016/j.athoracsur.2018.06.032.
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  - Siddiqui, Irfan, Sudarshan Rajagopal, Amanda Brucker, Karen Chiswell, Bridgette Christopher, Fawaz Alenezi, Aditya Mandawat, et al. “Clinical and Echocardiographic Predictors of Outcomes in Patients With Pulmonary Hypertension..” Am J Cardiol 122, no. 5 (September 1, 2018): 872–78. https://doi.org/10.1016/j.amjcard.2018.05.019.
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  - Thaden, Joshua T., Karen Chiswell, Ian Jaffe, Stephen P. Bergin, William E. Yang, Andrew Romaine, Jamie Roberts, et al. “Pediatric Antibacterial and Antifungal Trials From 2007 to 2017..” Pediatrics 142, no. 3 (September 2018). https://doi.org/10.1542/peds.2017-1849.
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  - Pagidipati, Neha J., Robert M. Clare, Robert T. Keenan, Karen Chiswell, Matthew T. Roe, and Connie N. Hess. “Association of Gout With Long-Term Cardiovascular Outcomes Among Patients With Obstructive Coronary Artery Disease..” J Am Heart Assoc 7, no. 16 (August 21, 2018). https://doi.org/10.1161/JAHA.118.009328.
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  - Henry, Timothy D., Douglas W. Losordo, Jay H. Traverse, Richard A. Schatz, E Marc Jolicoeur, Gary L. Schaer, Robert Clare, et al. “Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials..” Eur Heart J 39, no. 23 (June 14, 2018): 2208–16. https://doi.org/10.1093/eurheartj/ehx764.
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  - Basra, Sukhdeep S., Tracy Y. Wang, DaJuanicia N. Simon, Karen Chiswell, Salim S. Virani, Mahboob Alam, Vijay Nambi, et al. “Ticagrelor Use in Acute Myocardial Infarction: Insights From the National Cardiovascular Data Registry..” J Am Heart Assoc 7, no. 12 (June 9, 2018). https://doi.org/10.1161/JAHA.117.008125.
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  - Il’Giovine, Zachary J., Hillary Mulder, Karen Chiswell, Kristine Arges, Jennifer Tomfohr, Abraham Hashmi, Eric J. Velazquez, Joseph A. Kisslo, Zainab Samad, and Sudarshan Rajagopal. “Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software..” J Am Soc Echocardiogr 31, no. 6 (June 2018): 721-732.e5. https://doi.org/10.1016/j.echo.2018.01.008.
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  - Green, Jacqueline L., Alice K. Jacobs, DaJuanicia Holmes, Karen Chiswell, Rosalia Blanco, Eric R. Bates, William French, et al. “Taking the Reins on Systems of Care for ST-Segment-Elevation Myocardial Infarction Patients: A Report From the American Heart Association Mission: Lifeline Program..” Circ Cardiovasc Interv 11, no. 5 (May 2018). https://doi.org/10.1161/CIRCINTERVENTIONS.117.005706.
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  - Sze, E., Z. Samad, A. Dunning, K. B. Campbell, Z. Loring, B. D. Atwater, K. Chiswell, J. A. Kisslo, E. J. Velazquez, and J. P. Daubert. “Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block (vol 71, pg 306, 2018).” Journal of the American College of Cardiology 71, no. 11 (March 20, 2018): 1296–1296.
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  - Malta Hansen, Carolina, Tracy Y. Wang, Anita Y. Chen, Karen Chiswell, Deepak L. Bhatt, Jonathan R. Enriquez, Timothy Henry, and Matthew T. Roe. “Contemporary Patterns of Early Coronary Angiography Use in Patients With Non-ST-Segment Elevation Myocardial Infarction in the United States: Insights From the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry..” Jacc Cardiovasc Interv 11, no. 4 (February 26, 2018): 369–80. https://doi.org/10.1016/j.jcin.2017.12.016.
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  - Riley, Isaretta L., L Ebony Boulware, Jie-Lena Sun, Karen Chiswell, Loretta G. Que, Monica Kraft, Jamie L. Todd, Scott M. Palmer, and Monique L. Anderson. “Factors associated with reporting results for pulmonary clinical trials in ClinicalTrials.gov..” Clin Trials 15, no. 1 (February 2018): 87–94. https://doi.org/10.1177/1740774517740352.
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  - Sze, Edward, Zainab Samad, Allison Dunning, Kristen Bova Campbell, Zak Loring, Brett D. Atwater, Karen Chiswell, Joseph A. Kisslo, Eric J. Velazquez, and James P. Daubert. “Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block..” J Am Coll Cardiol 71, no. 3 (January 23, 2018): 306–17. https://doi.org/10.1016/j.jacc.2017.11.020.
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  - Doll, Jacob A., Shuang Li, Karen Chiswell, Matthew T. Roe, Mikhail Kosiborod, Benjamin M. Scirica, and Tracy Y. Wang. “Clopidogrel reloading for patients with acute myocardial infarction already on clopidogrel therapy..” Eur Heart J 39, no. 3 (January 14, 2018): 193–200. https://doi.org/10.1093/eurheartj/ehx255.
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  - Hagström, E., F. Norlund, A. Stebbins, P. W. Armstrong, K. Chiswell, C. B. Granger, J. López-Sendón, et al. “Psychosocial stress and major cardiovascular events in patients with stable coronary heart disease..” J Intern Med 283, no. 1 (January 2018): 83–92. https://doi.org/10.1111/joim.12692.
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  - Mody, Purav, Tracy Wang, Robert McNamara, Sandeep Das, Shuang Li, Karen Chiswell, Thomas Tsai, et al. “Association of acute kidney injury and chronic kidney disease with processes of care and long-term outcomes in patients with acute myocardial infarction..” Eur Heart J Qual Care Clin Outcomes 4, no. 1 (January 1, 2018): 43–50. https://doi.org/10.1093/ehjqcco/qcx020.
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  - Krishnamoorthy, Arun, Adam D. DeVore, Jie-Lena Sun, Adam S. Barnett, Marc D. Samsky, Linda K. Shaw, Karen Chiswell, Chetan B. Patel, and Manesh R. Patel. “The impact of a failing right heart in patients supported by intra-aortic balloon counterpulsation..” Eur Heart J Acute Cardiovasc Care 6, no. 8 (December 2017): 709–18. https://doi.org/10.1177/2048872616652262.
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  - Smilowitz, Nathaniel R., Asha M. Mahajan, Matthew T. Roe, Anne S. Hellkamp, Karen Chiswell, Martha Gulati, and Harmony R. Reynolds. “Mortality of Myocardial Infarction by Sex, Age, and Obstructive Coronary Artery Disease Status in the ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines)..” Circ Cardiovasc Qual Outcomes 10, no. 12 (December 2017). https://doi.org/10.1161/CIRCOUTCOMES.116.003443.
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  - Sze, Edward, Allison Dunning, Zak Loring, Brett D. Atwater, Karen Chiswell, James P. Daubert, Joseph A. Kisslo, Daniel B. Mark, Eric J. Velazquez, and Zainab Samad. “Comparison of Incidence of Left Ventricular Systolic Dysfunction Among Patients With Left Bundle Branch Block Versus Those With Normal QRS Duration..” Am J Cardiol 120, no. 11 (December 1, 2017): 1990–97. https://doi.org/10.1016/j.amjcard.2017.08.003.
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  - Kragholm, Kristian, Di Lu, Karen Chiswell, Hussein R. Al-Khalidi, Mayme L. Roettig, Matthew Roe, James Jollis, and Christopher B. Granger. “Improvement in Care and Outcomes for Emergency Medical Service-Transported Patients With ST-Elevation Myocardial Infarction (STEMI) With and Without Prehospital Cardiac Arrest: A Mission: Lifeline STEMI Accelerator Study..” J Am Heart Assoc 6, no. 10 (October 11, 2017). https://doi.org/10.1161/JAHA.117.005717.
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  - Vidal-Petiot, Emmanuelle, Amanda Stebbins, Karen Chiswell, Diego Ardissino, Philip E. Aylward, Christopher P. Cannon, Marco A. Ramos Corrales, et al. “Visit-to-visit variability of blood pressure and cardiovascular outcomes in patients with stable coronary heart disease. Insights from the STABILITY trial..” European Heart Journal 38, no. 37 (October 2017): 2813–22. https://doi.org/10.1093/eurheartj/ehx250.
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  - Badri, Marwan, Amr Abdelbaky, Shuang Li, Karen Chiswell, and Tracy Y. Wang. “Precatheterization Use of P2Y12 Inhibitors in Non-ST-Elevation Myocardial Infarction Patients Undergoing Early Cardiac Catheterization and In-Hospital Coronary Artery Bypass Grafting: Insights From the National Cardiovascular Data Registry®..” J Am Heart Assoc 6, no. 9 (September 22, 2017). https://doi.org/10.1161/JAHA.117.006508.
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  - Guimarães, Patricia Oliveira, Christopher B. Granger, Amanda Stebbins, Karen Chiswell, Claes Held, Judith S. Hochman, Susan Krug-Gourley, et al. “Sex Differences in Clinical Characteristics, Psychosocial Factors, and Outcomes Among Patients With Stable Coronary Heart Disease: Insights from the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial..” J Am Heart Assoc 6, no. 9 (September 14, 2017). https://doi.org/10.1161/JAHA.117.006695.
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  - Vora, Amit N., Tracy Y. Wang, Shuang Li, Karen Chiswell, Connie Hess, Renato D. Lopes, Sunil V. Rao, and Eric D. Peterson. “Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines..” J Am Heart Assoc 6, no. 8 (August 21, 2017). https://doi.org/10.1161/JAHA.116.005280.
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  - Pi, Yi, Matthew T. Roe, DaJuanicia N. Holmes, Karen Chiswell, J Lee Garvey, Gregg C. Fonarow, James A. de Lemos, Kirk N. Garratt, and Ying Xian. “Utilization, Characteristics, and In-Hospital Outcomes of Coronary Artery Bypass Grafting in Patients With ST-Segment-Elevation Myocardial Infarction: Results From the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines..” Circ Cardiovasc Qual Outcomes 10, no. 8 (August 2017). https://doi.org/10.1161/CIRCOUTCOMES.116.003490.
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  - Pandey, Ambarish, Harsh Golwala, Hurst M. Hall, Tracy Y. Wang, Di Lu, Ying Xian, Karen Chiswell, et al. “Association of US Centers for Medicare and Medicaid Services Hospital 30-Day Risk-Standardized Readmission Metric With Care Quality and Outcomes After Acute Myocardial Infarction: Findings From the National Cardiovascular Data Registry/Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines..” Jama Cardiol 2, no. 7 (July 1, 2017): 723–31. https://doi.org/10.1001/jamacardio.2017.1143.
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  - Banks, Adam, Samuel Broderick, Karen Chiswell, Linda Shaw, Adam Devore, Mona Fiuzat, Christopher O’Connor, Gary Michael Felker, Eric Velazquez, and Robert Mentz. “Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease)..” Am J Cardiol 119, no. 11 (June 1, 2017): 1703–9. https://doi.org/10.1016/j.amjcard.2017.02.053.
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  - Randolph, Tiffany C., Samuel Broderick, Linda K. Shaw, Karen Chiswell, Robert J. Mentz, Valentina Kutyifa, Eric J. Velazquez, Francis R. Gilliam, and Kevin L. Thomas. “Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction..” J Am Heart Assoc 6, no. 3 (March 20, 2017). https://doi.org/10.1161/JAHA.116.004381.
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  - Roswell, Robert O., Jordan Kunkes, Anita Y. Chen, Karen Chiswell, Sohah Iqbal, Matthew T. Roe, and Sripal Bangalore. “Impact of Sex and Contact-to-Device Time on Clinical Outcomes in Acute ST-Segment Elevation Myocardial Infarction-Findings From the National Cardiovascular Data Registry..” J Am Heart Assoc 6, no. 1 (January 11, 2017). https://doi.org/10.1161/JAHA.116.004521.
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  - Shah, Rohan, Robert M. Clare, Karen Chiswell, W Schuyler Jones, A Sreenivas Kumar, Holger Thiele, Richard W. Smalling, et al. “Impact of Non-Infarct-Related Artery Disease on Infarct Size and Outcomes (from the CRISP-AMI Trial)..” Am J Med 129, no. 12 (December 2016): 1307–15. https://doi.org/10.1016/j.amjmed.2016.07.011.
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  - Douglas, Pamela S., Bernard De Bruyne, Gianluca Pontone, Manesh R. Patel, Bjarne L. Norgaard, Robert A. Byrne, Nick Curzen, et al. “1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease: The PLATFORM Study..” J Am Coll Cardiol 68, no. 5 (August 2, 2016): 435–45. https://doi.org/10.1016/j.jacc.2016.05.057.
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  - Stewart, Ralph A. H., Lars Wallentin, Jocelyne Benatar, Nicolas Danchin, Emil Hagström, Claes Held, Steen Husted, et al. “Dietary patterns and the risk of major adverse cardiovascular events in a global study of high-risk patients with stable coronary heart disease..” European Heart Journal 37, no. 25 (July 2016): 1993–2001. https://doi.org/10.1093/eurheartj/ehw125.
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  - Kohl, Louis P., Jeffrey D. Leimberger, Karen Chiswell, W Schuyler Jones, Holger Thiele, Richard W. Smalling, Praveen Chandra, et al. “Clinical characteristics and outcomes after unplanned intraaortic balloon counterpulsation in the Counterpulsation to Reduce Infarct Size Pre-PCI Acute Myocardial Infarction trial..” Am Heart J 174 (April 2016): 7–13. https://doi.org/10.1016/j.ahj.2015.12.004.
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  - Barnard, Karen, Wanda C. Lakey, Bryan C. Batch, Karen Chiswell, Asba Tasneem, and Jennifer B. Green. “Recent Clinical Trials in Osteoporosis: A Firm Foundation or Falling Short?.” Plos One 11, no. 5 (2016). https://doi.org/10.1371/journal.pone.0156068.
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  - Douglas, Pamela S., Gianluca Pontone, Mark A. Hlatky, Manesh R. Patel, Bjarne L. Norgaard, Robert A. Byrne, Nick Curzen, et al. “Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR(CT): outcome and resource impacts study..” Eur Heart J 36, no. 47 (December 14, 2015): 3359–67. https://doi.org/10.1093/eurheartj/ehv444.
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  - Ruopp, Marcus, Karen Chiswell, Joshua T. Thaden, Kunal Merchant, and Ephraim L. Tsalik. “Respiratory Tract Infection Clinical Trials from 2007 to 2012. A Systematic Review of ClinicalTrials.gov..” Ann Am Thorac Soc 12, no. 12 (December 2015): 1852–63. https://doi.org/10.1513/AnnalsATS.201505-291OC.
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  - Mentz, Robert J., Eric J. Velazquez, Marco Metra, Colleen McKendry, Karen Chiswell, Mona Fiuzat, Michael M. Givertz, Adriaan A. Voors, John R. Teerlink, and Christopher M. O’Connor. “Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial..” Future Cardiol 11, no. 5 (September 2015): 585–95. https://doi.org/10.2217/fca.15.56.
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  - Pontone, Gianluca, Manesh R. Patel, Mark A. Hlatky, Karen Chiswell, Daniele Andreini, Bjarne Linde Norgaard, Robert A. Byrne, et al. “Rationale and design of the Prospective LongitudinAl Trial of FFRCT: Outcome and Resource IMpacts study..” Am Heart J 170, no. 3 (September 2015): 438-46.e44. https://doi.org/10.1016/j.ahj.2015.06.002.
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  - Hess, Connie N., Matthew T. Roe, Robert M. Clare, Karen Chiswell, Joseph Kelly, James E. Tcheng, Emil Hagstrom, et al. “Relationship Between Cancer and Cardiovascular Outcomes Following Percutaneous Coronary Intervention..” J Am Heart Assoc 4, no. 7 (July 6, 2015). https://doi.org/10.1161/JAHA.115.001779.
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  - Mentz, Robert J., Marco Metra, Gad Cotter, Olga Milo, Colleen McKendry, Karen Chiswell, Beth A. Davison, et al. “Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial..” Eur J Heart Fail 17, no. 7 (July 2015): 697–706. https://doi.org/10.1002/ejhf.308.
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  - Holmqvist, Fredrik, Kevin L. Thomas, Samuel Broderick, Mads Ersbøll, Devinder Singh, Karen Chiswell, Linda K. Shaw, Donald D. Hegland, Eric J. Velazquez, and James P. Daubert. “Clinical outcome as a function of the PR-interval-there is virtue in moderation: data from the Duke Databank for cardiovascular disease..” Europace 17, no. 6 (June 2015): 978–85. https://doi.org/10.1093/europace/euu211.
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  - Anderson, Monique L., Karen Chiswell, Eric D. Peterson, Asba Tasneem, James Topping, and Robert M. Califf. “Compliance with results reporting at ClinicalTrials.gov..” N Engl J Med 372, no. 11 (March 12, 2015): 1031–39. https://doi.org/10.1056/NEJMsa1409364.
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  - Jones, W Schuyler, Robert M. Clare, Karen Chiswell, Divaka Perera, John K. French, A Sreenivas Kumar, Jonathan Blaxill, et al. “The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial..” Clin Cardiol 38, no. 1 (January 2015): 25–31. https://doi.org/10.1002/clc.22349.
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  - Metra, Marco, Robert J. Mentz, Karen Chiswell, Daniel M. Bloomfield, John G. F. Cleland, Gad Cotter, Beth A. Davison, et al. “Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial..” Eur J Heart Fail 17, no. 1 (January 2015): 109–18. https://doi.org/10.1002/ejhf.207.
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  - Subherwal, S., M. R. Patel, and K. Chiswell. “Clinical trials in peripheral vascular disease pipeline and trial designs: An evaluation of the clinical trials.gov database.” Journal of Vascular Surgery 61, no. 4 (January 1, 2015). https://doi.org/10.1016/j.jvs.2015.03.005.
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  - Mentz, Robert J., Samuel Broderick, Linda K. Shaw, Karen Chiswell, Mona Fiuzat, and Christopher M. O’Connor. “Persistent angina pectoris in ischaemic cardiomyopathy: increased rehospitalization and major adverse cardiac events..” Eur J Heart Fail 16, no. 8 (August 2014): 854–60. https://doi.org/10.1002/ejhf.130.
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  - Hill, Kevin D., Karen Chiswell, Robert M. Califf, Gail Pearson, and Jennifer S. Li. “Characteristics of pediatric cardiovascular clinical trials registered on ClinicalTrials.gov..” Am Heart J 167, no. 6 (June 2014): 921-9.e2. https://doi.org/10.1016/j.ahj.2014.02.002.
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  - Mentz, Robert J., Gad Cotter, John G. F. Cleland, Susanna R. Stevens, Karen Chiswell, Beth A. Davison, John R. Teerlink, et al. “International differences in clinical characteristics, management, and outcomes in acute heart failure patients: better short-term outcomes in patients enrolled in Eastern Europe and Russia in the PROTECT trial..” Eur J Heart Fail 16, no. 6 (June 2014): 614–24. https://doi.org/10.1002/ejhf.92.
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  - Inrig, Jula K., Robert M. Califf, Asba Tasneem, Radha K. Vegunta, Christopher Molina, John W. Stanifer, Karen Chiswell, and Uptal D. Patel. “The landscape of clinical trials in nephrology: a systematic review of Clinicaltrials.gov..” Am J Kidney Dis 63, no. 5 (May 2014): 771–80. https://doi.org/10.1053/j.ajkd.2013.10.043.
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  - Cleland, John G., Karen Chiswell, John R. Teerlink, Susanna Stevens, Mona Fiuzat, Michael M. Givertz, Beth A. Davison, et al. “Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function (PROTECT) Study..” Circ Heart Fail 7, no. 1 (January 2014): 76–87. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000284.
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  - Witsell, David L., Kristine A. Schulz, Walter T. Lee, and Karen Chiswell. “An analysis of registered clinical trials in otolaryngology from 2007 to 2010: ClinicalTrials.gov..” Otolaryngol Head Neck Surg 149, no. 5 (November 2013): 692–99. https://doi.org/10.1177/0194599813506545.
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  - Todd, Jamie L., Kyle R. White, Karen Chiswell, Asba Tasneem, and Scott M. Palmer. “Using ClinicalTrials.gov to understand the state of clinical research in pulmonary, critical care, and sleep medicine..” Ann Am Thorac Soc 10, no. 5 (October 2013): 411–17. https://doi.org/10.1513/AnnalsATS.201305-111OC.
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  - Alexander, Karen P., David F. Kong, Aijing Z. Starr, Judith Kramer, Karen Chiswell, Asba Tasneem, and Robert M. Califf. “Portfolio of clinical research in adult cardiovascular disease as reflected in ClinicalTrials.gov..” J Am Heart Assoc 2, no. 5 (September 26, 2013). https://doi.org/10.1161/JAHA.113.000009.
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  - Vavalle, John P., Robert Clare, Karen Chiswell, Sunil V. Rao, John L. Petersen, Neal S. Kleiman, Kenneth W. Mahaffey, and Tracy Y. Wang. “Prognostic significance of bleeding location and severity among patients with acute coronary syndromes..” Jacc Cardiovasc Interv 6, no. 7 (July 2013): 709–17. https://doi.org/10.1016/j.jcin.2013.03.010.
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  - Hirsch, Bradford R., Robert M. Califf, Steven K. Cheng, Asba Tasneem, John Horton, Karen Chiswell, Kevin A. Schulman, David M. Dilts, and Amy P. Abernethy. “Characteristics of oncology clinical trials: insights from a systematic analysis of ClinicalTrials.gov..” Jama Intern Med 173, no. 11 (June 10, 2013): 972–79. https://doi.org/10.1001/jamainternmed.2013.627.
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  - Lakey, W. C., K. Barnard, B. C. Batch, K. Chiswell, A. Tasneem, and J. B. Green. “Are current clinical trials in diabetes addressing important issues in diabetes care?.” Diabetologia 56, no. 6 (June 2013): 1226–35. https://doi.org/10.1007/s00125-013-2890-4.
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  - Rose, Jason J., L Kristin Newby, Samuel Broderick, Karen Chiswell, Frans Van de Werf, Paul W. Armstrong, Kenneth W. Mahaffey, et al. “Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes..” J Am Coll Cardiol 61, no. 13 (April 2, 2013): 1461–63. https://doi.org/10.1016/j.jacc.2012.12.032.
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  - Berger, Peter B., Judson B. Williams, Vic Hasselblad, Karen Chiswell, Karen S. Pieper, and Robert M. Califf. “Would tirofiban have been shown non-inferior to abciximab had the TENACITY trial not been terminated for financial reasons?.” J Interv Cardiol 26, no. 2 (April 2013): 123–30. https://doi.org/10.1111/j.1540-8183.2013.12020.x.
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  - Mentz, Robert J., Daniel Wojdyla, Mona Fiuzat, Karen Chiswell, Gregg C. Fonarow, and Christopher M. O’Connor. “Association of beta-blocker use and selectivity with outcomes in patients with heart failure and chronic obstructive pulmonary disease (from OPTIMIZE-HF)..” Am J Cardiol 111, no. 4 (February 15, 2013): 582–87. https://doi.org/10.1016/j.amjcard.2012.10.041.
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  - Goswami, Neela D., Christopher D. Pfeiffer, John R. Horton, Karen Chiswell, Asba Tasneem, and Ephraim L. Tsalik. “The state of infectious diseases clinical trials: a systematic review of ClinicalTrials.gov..” Plos One 8, no. 10 (2013). https://doi.org/10.1371/journal.pone.0077086.
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  - Williams, Eric S., Vivian P. Thompson, Karen E. Chiswell, John H. Alexander, Harvey D. White, E Magnus Ohman, and Sana M. Al-Khatib. “Rate versus rhythm control and outcomes in patients with atrial fibrillation and chronic kidney disease: data from the GUSTO-III Trial..” Cardiol J 20, no. 4 (2013): 439–46. https://doi.org/10.5603/CJ.2013.0104.
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  - Pasquali, Sara K., Wendy K. Lam, Karen Chiswell, Alex R. Kemper, and Jennifer S. Li. “Status of the pediatric clinical trials enterprise: an analysis of the US ClinicalTrials.gov registry..” Pediatrics 130, no. 5 (November 2012): e1269–77. https://doi.org/10.1542/peds.2011-3565.
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  - Green, J. B., W. Lakey, K. Barnard, B. Batch, M. Bethel, K. Chiswell, and A. Tasneem. “State of diabetes-related trials in the clinicaltrials.gov dataset.” Diabetologia 55 (October 1, 2012): S90–91.
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  - Thomas, Michael P., Kenneth W. Mahaffey, Karen Chiswell, Marc Cohen, Michael C. Kontos, Elliott M. Antman, James J. Ferguson, Robert M. Califf, Shaun G. Goodman, and Richard C. Becker. “Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin..” J Thromb Thrombolysis 34, no. 1 (July 2012): 114–19. https://doi.org/10.1007/s11239-012-0693-y.
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  - O’Connor, Christopher M., Robert J. Mentz, Gad Cotter, Marco Metra, John G. Cleland, Beth A. Davison, Michael M. Givertz, et al. “The PROTECT in-hospital risk model: 7-day outcome in patients hospitalized with acute heart failure and renal dysfunction..” Eur J Heart Fail 14, no. 6 (June 2012): 605–12. https://doi.org/10.1093/eurjhf/hfs029.
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  - Mentz, Robert J., Mona Fiuzat, Daniel M. Wojdyla, Karen Chiswell, Mihai Gheorghiade, Gregg C. Fonarow, and Christopher M. O’Connor. “Clinical characteristics and outcomes of hospitalized heart failure patients with systolic dysfunction and chronic obstructive pulmonary disease: findings from OPTIMIZE-HF..” Eur J Heart Fail 14, no. 4 (April 2012): 395–403. https://doi.org/10.1093/eurjhf/hfs009.
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  - Novick, S., K. Chiswell, and J. Peterson. “A Bayesian Approach to Show Assay Equivalence with Replicate Measurements Over a Specified Response Range.” Statistics in Biopharmaceutical Research 4, no. 2 (April 1, 2012): 102–17. https://doi.org/10.1198/sbr.2010.09049.
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  - Tasneem, Asba, Laura Aberle, Hari Ananth, Swati Chakraborty, Karen Chiswell, Brian J. McCourt, and Ricardo Pietrobon. “The database for aggregate analysis of ClinicalTrials.gov (AACT) and subsequent regrouping by clinical specialty..” Plos One 7, no. 3 (2012). https://doi.org/10.1371/journal.pone.0033677.
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  - Hirsch, B. R., R. M. Califf, A. Tasneem, K. Chiswell, J. Bolte, K. A. Schulman, and A. P. Abernethy. “Assessment of clinical trials in oncology: An evaluation of 40,696 trials on ClinicalTrials.gov..” J Clin Oncol 29, no. 15_suppl (May 20, 2011).
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  - Goffinet, Christine, Ina Allespach, Lena Oberbremer, Pamela L. Golden, Scott A. Foster, Brian A. Johns, Jason G. Weatherhead, et al. “Pharmacovirological impact of an integrase inhibitor on human immunodeficiency virus type 1 cDNA species in vivo..” Journal of Virology 83, no. 15 (August 2009): 7706–17. https://doi.org/10.1128/JVI.00683-09.
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  - Muniz-Medina, Vanessa M., Stacey Jones, Jodi M. Maglich, Cristin Galardi, Robert E. Hollingsworth, Wieslaw M. Kazmierski, Robert G. Ferris, Mark P. Edelstein, Karen E. Chiswell, and Terry P. Kenakin. “The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property?.” Molecular Pharmacology 75, no. 3 (March 2009): 490–501. https://doi.org/10.1124/mol.108.052555.
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  - Rao, Sunil V., Karen Chiswell, Jie-Lena Sun, Christopher B. Granger, L Kristin Newby, Frans Van de Werf, Harvey D. White, Paul W. Armstong, Robert M. Califf, and Robert A. Harrington. “International variation in the use of blood transfusion in patients with non-ST-segment elevation acute coronary syndromes..” Am J Cardiol 101, no. 1 (January 1, 2008): 25–29. https://doi.org/10.1016/j.amjcard.2007.07.042.
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  - Fonarow, Gregg C., Mary Ann Lukas, Michele Robertson, Wilson S. Colucci, and Henry J. Dargie. “Effects of carvedilol early after myocardial infarction: Analysis of the first 30 days in Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN).” American Heart Journal 154, no. 4 (October 2007): 637–44. https://doi.org/10.1016/j.ahj.2007.06.002.
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  - Greenberg, B. H., W. T. Abraham, N. M. Albert, K. Chiswell, R. Clare, W. G. Stough, M. Gheorghiade, et al. “Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: A report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).” American Heart Journal 154, no. 4 (October 1, 2007): 647–54. https://doi.org/10.1016/j.ahj.2007.08.002.
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  - Greenberg, Barry H., William T. Abraham, Nancy M. Albert, Karen Chiswell, Robert Clare, Wendy Gattis Stough, Mihai Gheorghiade, et al. “Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: a report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)..” Am Heart J 154, no. 2 (August 2007): 277.e1-277.e8. https://doi.org/10.1016/j.ahj.2007.05.001.
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  - Albert, Nancy M., Gregg C. Fonarow, William T. Abraham, Karen Chiswell, Wendy Gattis Stough, Mihai Gheorghiade, Barry H. Greenberg, et al. “Predictors of delivery of hospital-based heart failure patient education: a report from OPTIMIZE-HF..” J Card Fail 13, no. 3 (April 2007): 189–98. https://doi.org/10.1016/j.cardfail.2006.11.008.
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  - White, Harvey D., Neal S. Kleiman, Kenneth W. Mahaffey, Yuliya Lokhnygina, Karen S. Pieper, Karen Chiswell, Marc Cohen, et al. “Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial..” Am Heart J 152, no. 6 (December 2006): 1042–50. https://doi.org/10.1016/j.ahj.2006.08.002.
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  - Chandler, R. E., K. E. Chiswell, and G. D. Faulkner. “Quantifying a possible miocene phyletic change in Hemipristis (Chondrichthyes) teeth.” Palaeontologia Electronica 9, no. 1 (February 6, 2006).
  - Viero, P. W. M., K. E. A. Chiswell, and J. M. Theron. “The effect of a soil-amended hydrogel on the establishment of a eucalyptus grandis clone on a sandy clay loam soil in zululand during winter.” Southern African Forestry Journal 193, no. 1 (March 1, 2002): 65–75. https://doi.org/10.1080/20702620.2002.10433519.
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- Conference Papers
  - Hein, Aaron M., Julia J. Scialla, Linda K. Shaw, Karen Chiswell, Patrick H. Pun, and Robert J. Mentz. “Increased eGFR Variability is Observed in Patients with HFrEF Compared to no HF or HFpEF in the Setting of Chronic Kidney Disease.” In Journal of Cardiac Failure, 25:S92–S92. Elsevier BV, 2019. https://doi.org/10.1016/j.cardfail.2019.07.263.
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  - Serfas, J. D., Toi Spates, Alfred D’Ottavio, Tracy Spears, Elizabeth Ciociola, Karen Chiswell, Manuela Wiedemeier, et al. “ADULTS AND ADOLESCENTS WITH CONGENITAL HEART DISEASE: WHO ARE WE LOSING TO FOLLOW UP?.” In Journal of the American College of Cardiology, 73:596–596. Elsevier BV, 2019. https://doi.org/10.1016/s0735-1097(19)31204-5.
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  - Tran, George Nhat, Matthew Harker, Karen Chiswell, Joseph M. Unger, Mark Fleury, Bradford Richard Hirsch, Kimberly Miller, Philip D’Almada, Sheri Tibbs, and Yousuf Zafar. “Feasibility of cancer clinical trial enrollment goals based on cancer incidence..” In Journal of Clinical Oncology, 36:20–20. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.30_suppl.20.
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  - Tran, George, Matthew Harker, Karen Chiswell, Mark Fleury, Bradford Richard Hirsch, Joseph M. Unger, Kimberly Miller, Philip D’Almada, Sheri Tibbs, and Yousuf Zafar. “Comparison of cancer incidence to available oncology clinical trial slots..” In Journal of Clinical Oncology, 36:e18615–e18615. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.e18615.
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  - Pokorney, Sean, Samuel Berchuck, Karen Chiswell, Linda Shaw, Laine Thomas, William Jones, Manesh Patel, and Jonathan Piccini. “ATRIAL ISCHEMIA AS A MECHANISM OF ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 71:A372–A372. Elsevier BV, 2018. https://doi.org/10.1016/s0735-1097(18)30913-6.
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  - Yankey, George, Zainab Samad, Angie Wu, Karen Chiswell, Larry Jackson, Jimica Wilson, Terrell Jones, and Kevin Thomas. “AORTIC VALVE REPLACEMENT AND OUTCOMES IN PATIENTS WITH SEVERE AORTIC STENOSIS: IS IT BLACK OR WHITE?.” In Journal of the American College of Cardiology, 71:A2010–A2010. Elsevier BV, 2018. https://doi.org/10.1016/s0735-1097(18)32551-8.
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  - Alenezi, Fawaz, Marat Fudim, Jennifer Rymer, Allison Dunning, Karen Chiswell, Joseph Kisslo, Kevin Harrison, et al. “Changes in Cardiac Hemodynamics and Geometry After Transcatheter Aortic Valve Replacement.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Bloomfield, Gerald S., Allison Dunning, Fawaz Alenezi, Nwora L. Okeke, Karen Chiswell, and Eric J. Velazquez. “Longitudinal Evaluation of Cardiac Structure and Function in Patients Living With Human Immunodeficiency Virus in the Anti-Retroviral Therapy Era.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Pagidipati, Neha J., Matthew Phelan, Karen Chiswell, and Eric D. Peterson. “Prevalence and Management of Adult Obesity in a Large Academic Health System.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Shavadia, Jay, Karen Chiswell, Roseann White, Leslie Stephens, Tanya Schikorr, Prajakta Bhounsule, and Mitchell Krucoff. “Prevalence and treatment patterns for in-stent restenosis: A single center report from the Duke Databank for Cardiovascular Disease.” In Journal of the American College of Cardiology, 70:B173–B173. ELSEVIER SCIENCE INC, 2017.
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  - Guimaraes, P Oliveira, C. B. Granger, K. Chiswell, A. Stebbins, C. Held, J. S. Hochman, S. Krug-Gourley, et al. “Women with stable coronary artery disease have better clinical outcomes than men, but this association is modified by degree of depression: insights from the STABILITY trial.” In European Heart Journal, 38:188–188. OXFORD UNIV PRESS, 2017.
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  - Sullivan, Lonnie T., Hillary Mulder, Karen Chiswell, Linda Shaw, Tracy Wang, and Kevin Thomas. “DUAL ANTIPLATELET THERAPY UTILIZATION AND CARDIOVASCULAR OUTCOMES AMONG BLACK AND WHITE PATIENTS TREATED WITH DRUG ELUTING STENTS.” In Journal of the American College of Cardiology, 69:1017–1017. ELSEVIER SCIENCE INC, 2017.
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  - Tasneem, Asba, Karen Chiswell, Brian J. McCourt, Matt Gross, Eric Peterson, and Michael J. Pencina. “Developing a framework for a comprehensive data sharing program..” In Amia. AMIA, 2017.
  - Tibbs, Sheri R., Karen Chiswell, and Sara Calvert. “Making Aggregate Content of ClinicalTrials.gov Freely Available to Everyone..” In Cri. AMIA, 2017.
  - Kragholm, Kristian, Di Lu, Karen Chiswell, Hussein Al-Khalidi, Mayme L. Roettig, Matthew Roe, James Jollis, and Christopher B. Granger. “Improvement in Care and Outcomes for Ambulance-Transported ST-Elevation Myocardial Infarction Patients With and Without Out-of-Hospital Cardiac Arrest: A Mission: Lifeline STEMI ACCELERATOR Study.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Patel, Priyesh A., Matthew Phelan, Michael MacKenzie, Karen Chiswell, Melissa K. Van Dyke, Jennifer Tomfohr, Fawaz A. Alenezi, Narimon Honarpour, and Eric J. Velazquez. “Shorter Left Ventricular Ejection Time is Associated With Adverse Outcomes in Heart Failure Patients With Reduced Ejection Fraction.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Patel, Priyesh A., Matthew Phelan, Michael MacKenzie, Karen Chiswell, Melissa K. Van Dyke, Jennifer Tomfohr, Fawaz A. Alenezi, Narimon Honarpour, and Eric J. Velazquez. “Shorter Left Ventricular Ejection Time is Associated With Adverse Outcomes in Heart Failure Patients With Reduced Ejection Fraction.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Siddiqui, Irfan, Sudarshan Rajagopal, Amanda Brucker, Karen Chiswell, Fawaz Al Enezi, Danny Rivera, Aditya Mandawat, et al. “Clinical and Echocardiographic Predictors of Clinical Outcomes in Pulmonary Arterial Hypertension.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Badri, Marwan, Amr Abdelbaky, Shuang Li, Karen Chiswell, and Tracy Wang. “ASSOCIATION BETWEEN PRE-CATHETERIZATION USE OF P2Y12 INHIBITORS WITH TIMING OF CABG AND CABG-RELATED OUTCOMES IN PATIENTS PRESENTING WITH NSTEMI AND SURGICAL CORONARY DISEASE: INSIGHTS FROM NCDR ®.” In Journal of the American College of Cardiology, 67:544–544. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30545-9.
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  - Basra, Sukhdeep S., Tracy Wang, DaJuanicia Simon, Karen Chiswell, Salim Virani, Mahboob Alam, Vijay Nambi, et al. “ASPIRIN DOSING IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION TREATED WITH TICAGRELOR: INSIGHT FROM THE NATIONAL CARDIOVASCULAR DATA REGISTRY (NCDR).” In Journal of the American College of Cardiology, 67:537–537. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30538-1.
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  - Douglas, Pamela S., Bernard De Bruyne, Gianluca Pontone, Manesh Patel, Bjarne Norgaard, Robert Byrne, Nick Curzen, et al. “LONG-TERM OUTCOMES OF AN FFRCT DIAGNOSTIC STRATEGY VERSUS USUAL CARE IN SUSPECTED CORONARY ARTERY DISEASE: RESULTS FROM THE PLATFORM (PROSPECTIVE LONGITUDINAL TRIAL OF FFRCT: OUTCOME AND RESOURCE IMPACTS) STUDY.” In Journal of the American College of Cardiology, 67:1589–1589. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)31590-x.
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  - Hansen, Carolina Malta, Tracy Wang, Anita Chen, Karen Chiswell, Deepak Bhatt, Jonathan Enriquez, Timothy Henry, and Matthew Roe. “HOSPITAL-LEVEL VARIATION IN THE USE OF EARLY CATHETERIZATION FOR PATIENTS WITH NON-ST ELEVATION MYOCARDIAL INFARCTION: INSIGHTS FROM THE NCDR ACTION REGISTRY-GWTG.” In Journal of the American College of Cardiology, 67:463–463. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30464-8.
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  - Kontos, Michael C., Christopher Fordyce, Jonathan Enriquez, Matthew Roe, Karen Chiswell, Anita Y. Chen, and Lee Garvey. “ASSOCIATION OF ACUTE MYOCARDIAL INFARCTION CARDIAC ARREST PATIENT VOLUME AND IN-HOSPITAL MORTALITY.” In Journal of the American College of Cardiology, 67:567–567. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30568-x.
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  - Pagidipati, Neha J., Daniel Mudrick, Karen Chiswell, Amanda Brucker, Michael Mackenzie, Songlin Zhu, Eric Peterson, and Pamela Douglas. “SEX DIFFERENCES IN LONG-TERM OUTCOMES OF PATIENTS WITH NON-OBSTRUCTIVE CORONARY ARTERY DISEASE.” In Journal of the American College of Cardiology, 67:1860–1860. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)31861-7.
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  - Pi, Yi, Matthew Roe, DaJuanicia Simon, Karen Chiswell, Lee Garvey, Gregg Fonarow, James de Lemos, and Ying Xian. “UTILIZATION, CHARACTERISTICS, AND IN-HOSPITAL OUTCOMES FOR PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION UNDERGOING IN-HOSPITAL CORONARY ARTERY BYPASS GRAFTING (CABG).” In Journal of the American College of Cardiology, 67:605–605. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30606-4.
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  - Smilowitz, Nathaniel R., Asha Mahajan, Matthew Roe, Anne Hellkamp, Karen Chiswell, Martha Gulati, and Harmony Reynolds. “IN-HOSPITAL MORTALITY OF MYOCARDIAL INFARCTION BY SEX, AGE, AND OBSTRUCTIVE CORONARY ARTERY DISEASE STATUS IN THE ACTION REGISTRY-GWTG.” In Journal of the American College of Cardiology, 67:461–461. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30462-4.
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  - Green, Jacqueline L., Alice K. Jacobs, DaJuanicia N. Simon, Karen Chiswell, Rosalie Blanco, Eric R. Bates, William French, et al. “Are State Policies to Permit Pre-hospital Bypass Associated With Better Treatment Patterns Among Patients With ST-Elevation Myocardial Infarction? A Report From AHA's Mission: Lifeline Program.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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  - Harskamp, Ralf E., Karen Chiswell, Sharif Halim, Jennifer Rymer, Linda Shaw, and L Kristin Newby. “Revascularization versus Optimal Medical Therapy for Patients With Prior Coronary Artery Bypass Surgery: An Analysis From the Duke Databank for Cardiovascular Disease.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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  - Riley, Isaretta, L Ebony Boulware, Jie-Lena Sun, Karen Chiswell, Loretta Que, Robert Califf, Monica Kraft, and Monique Anderson. “Race/Ethnicity Reporting for Pulmonary Clinical Trials in ClinicalTrials.gov.” In Chest, 148:357A-357A. Elsevier BV, 2015. https://doi.org/10.1378/chest.2235991.
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  - Held, C., H. D. White, R. A. H. Stewart, R. Davies, S. H. Sampson, K. Chiswell, U. Boden, K. W. Mahaffey, and L. Wallentin. “Characterization of cardiovascular endpoints, impact of event adjudication and effects of darapladib in the STABILITY trial.” In European Heart Journal, 36:1104–1104. OXFORD UNIV PRESS, 2015.
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  - Psotka, Mitchell A., John R. Teerlink, Karen Chiswell, John G. Cleland, Gad Cotter, Beth A. Davison, Michael M. Givertz, et al. “Prediction of Post-Discharge Outcomes for Patients Hospitalized with Heart Failure: Results from PROTECT.” In Journal of Cardiac Failure, 21:S64–S64. Elsevier BV, 2015. https://doi.org/10.1016/j.cardfail.2015.06.205.
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  - Stewart, R. A. H., P. W. Armstrong, K. Chiswell, E. Hagstrom, C. Held, S. Krug-Gourley, C. M. Ryan, A. Stebbins, L. Wallentin, and H. D. White. “Effect of ivabradine on heart rate variability in patients with stable coronary artery disease.” In European Heart Journal, 36:1088–1088. OXFORD UNIV PRESS, 2015.
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  - Kakkar, A. K., G. Accetta, G. Agnelli, P. Angchaisuksiri, J. -. P. Bassand, K. Chiswell, F. Cools, et al. “Risk profiles and 1-year outcomes of patients with newly diagnosed atrial fibrillation: results from GARFIELD-AF.” In Journal of Thrombosis and Haemostasis, 13:139–139. WILEY-BLACKWELL, 2015.
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  - Randolph, Tiffany, Samuel Broderick, Linda Shaw, Robert Mentz, Karen Chiswell, Francis Gilliam, and Kevin Thomas. “RACE AND SEX DIFFERENCES IN THE QRS INTERVAL AMONG PATIENTS WITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTION.” In Journal of the American College of Cardiology, 65:A815–A815. Elsevier BV, 2015. https://doi.org/10.1016/s0735-1097(15)60815-4.
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  - DeVore, Adam D., Eric Yow, Mitchell W. Krucoff, Linda K. Shaw, Karen Chiswell, Christopher M. O’Connor, E Magnus Ohman, and Eric J. Velazquez. “Outcomes After Percutaneous Coronary Intervention for Patients With Stable Coronary Disease and Left Ventricular Systolic Dysfunction.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Subherwal, Sumeet, Manesh R. Patel, Karen Chiswell, Beth A. Tidemann-Miller, W Schuyler Jones, Michael S. Conte, Christopher J. White, et al. “Clinical trials in peripheral vascular disease: pipeline and trial designs: an evaluation of the ClinicalTrials.gov database..” In Circulation, 130:1812–19, 2014. https://doi.org/10.1161/CIRCULATIONAHA.114.011021.
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  - Holmqvist, Fredrik, Kevin L. Thomas, Samuel Broderick, Mads Ersboll, Devinder Singh, Karen Chiswell, Linda K. Shaw, Donald D. Hegland, Eric J. Velazquez, and James P. Daubert. “Heart Rhythm Disorders and Resuscitation Science.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Mentz, Robert J., Samuel Broderick, Linda K. Shaw, Karen Chiswell, Mona Fiuzat, and Christopher M. O’Connor. “Clinical Characteristics and Outcomes of Patients With Ischemic Cardiomyopathy and Persistent Angina Pectoris: From the Duke Databank for Cardiovascular Disease.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Shah, Ankoor, Samuel Broderick, Karen Chiswell, Asba Tasneem, and John S. Sundy. “Status of the Allergy and Immunology Clinical Trials Portfolio: Data From Clinicaltrials.Gov.” In Journal of Allergy and Clinical Immunology, 131:AB107–AB107. Elsevier BV, 2013. https://doi.org/10.1016/j.jaci.2012.12.1055.
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  - Shah, Ankoor, Samuel Broderick, Karen Chiswell, Asba Tasneem, and John S. Sundy. “Status of the Rheumatology Clinical Trials Portfolio: Data From Clinicaltrials.Gov..” In Arthritis and Rheumatism, 64:S785–86. WILEY-BLACKWELL, 2012.
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  - Metra, M., K. Chiswell, M. Fiuzat, V. Lazzarini, J. Horton, B. Davison, J. Cleland, et al. “Age, Clinical Characteristics and Outcomes of Patients With Acute Decompensated Heart Failure: Insights from the PROTECT Trial.” In Journal of Cardiac Failure, 18:S76–S76. Elsevier BV, 2012. https://doi.org/10.1016/j.cardfail.2012.06.484.
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  - Cleland, John, Karen Chiswell, Gerasimos Filippatos, Michael Givertz, Barry Massie, Gad Cotter, Beth Davison, et al. “QUALITY OF LIFE 60 DAYS AFTER AN ACUTE HEART FAILURE EVENT: INSIGHTS FROM THE PROTECT TRIAL.” In Journal of the American College of Cardiology, 59:E1032–E1032. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)61033-x.
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  - Mentz, Robert J., Daniel Wojdyla, Mona Fiuzat, Karen Chiswell, Tariq Ahmad, Gregg Fonarow, and Christopher O'Connor. “THE ASSOCIATION OF BETA-BLOCKER USE AND SELECTIVITY WITH OUTCOMES IN HEART FAILURE PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: FINDINGS FROM THE ORGANIZED PROGRAM TO INITIATE LIFE-SAVING TREATMENT IN HOSPITALIZED PATIENTS WITH HEART FAILURE.” In Journal of the American College of Cardiology, 59:E862–E862. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)60863-8.
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  - Fiuzat, Mona, Daniel Wojdyla, David Whellan, Karen Chiswell, Dalane Kitzman, William Kraus, Steven Keteyian, et al. “Relationship of Beta-Blocker (BB) Dose with Outcomes in Ambulatory Heart Failure (HF) Patients with Systolic Dysfunction: Results from the HF-ACTION Trial.” In Circulation, Vol. 124. LIPPINCOTT WILLIAMS & WILKINS, 2011.
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  - Fiuzat, M., B. Massie, K. Chiswell, M. Givertz, B. Davison, G. Cotter, J. Cleland, et al. “International Differences in Acute Heart Failure (AHF) Patients: Insight from the PROTECT Trial.” In Journal of Cardiac Failure, 17:S59–60. Elsevier BV, 2011. https://doi.org/10.1016/j.cardfail.2011.06.203.
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  - Mentz, R. J., M. Fiuzat, D. Wojdyla, K. Chiswell, K. Pieper, M. Gheorghiade, G. C. Fonarow, and C. M. O’Connor. “Clinical Characteristics and Outcomes for Hospitalized Heart Failure (HF) Patients with Chronic Obstructive Pulmonary Disease (COPD): Findings from OPTIMIZE-HF.” In Journal of Cardiac Failure, 17:S86–87. Elsevier BV, 2011. https://doi.org/10.1016/j.cardfail.2011.06.293.
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  - Mentz, R. J., M. Fiuzat, K. Chiswell, D. Wojdyla, B. Davison, J. Cleland, H. C. Dittrich, et al. “The PROTECT In-Hospital Risk Model: 7-Day Outcome in Patients Hospitalized with Acute Heart Failure (AHF) and Renal Dysfunction.” In Journal of Cardiac Failure, 17:S77–S77. Elsevier BV, 2011. https://doi.org/10.1016/j.cardfail.2011.06.258.
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  - Hirsch, B. R., R. M. Califf, A. Tasneem, K. Chiswell, J. Bolte, K. A. Schulman, and A. P. Abernethy. “Assessment of clinical trials in oncology: An evaluation of 40,696 trials on ClinicalTrials.gov..” In Journal of Clinical Oncology, 29:6095–6095. American Society of Clinical Oncology (ASCO), 2011. https://doi.org/10.1200/jco.2011.29.15_suppl.6095.
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  - Harigaya, Y., K. E. Chiswell, J. L. Hoover, and M. J. Fossler. “USE OF MONTE CARLO SIMULATION (MCS) TO EVALUATE TOXICITY AND EFFICACY BREAKPOINTS OF A NOVEL ANTIBIOTIC.” In Clinical Pharmacology & Therapeutics, 85:S29–S29. NATURE PUBLISHING GROUP, 2009.
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  - Goodman, Shaun G., Kenneth W. Mahaffey, Karen Chiswell, Marc Cohen, Michael C. Kontos, Elliott M. Antman, James J. Ferguson, Robert M. Califf, and Richard Becker. “Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin.” In Journal of the American College of Cardiology, 49:186A-186A. ELSEVIER SCIENCE INC, 2007.
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  - Albert, Nancy M., G. Fonarow, W. Abraham, K. Chiswell, W Gattis Stough, M. Gheorghiade, B. Greenberg, C. ’. O’Connor, C. Yancy, and J. Young. “Do hospitals that provide heart failure patient education prior to discharge also promote continuity of care? A report from OPTIMIZE-HF.” In Journal of Cardiac Failure, 12:S112–S112. CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, 2006.
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  - Abraham, W. T., B. Greenberg, G. C. Fonarow, N. M. Albert, K. Chiswell, W. G. Stough, M. Gheorghiade, et al. “Cardiac resynchronization device placement during hospitalization for heart failure is associated with a significant improvement in early clinical outcomes.” In Journal of the American College of Cardiology, 47:19A-19A. ELSEVIER SCIENCE INC, 2006.
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  - Albert, N. M., G. C. Fonarow, W. T. Abraham, K. Chiswell, W. G. Stough, M. Gheorghiade, B. Greenberg, C. M. O’Connor, C. Yancy, and J. B. Young. “Do hospitals that provide heart failure patient education prior to discharge also promote continuity of care? - A report from OPTIMIZE-HF.” In Journal of the American College of Cardiology, 47:267A-268A. ELSEVIER SCIENCE INC, 2006.
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  - Ferrarow, G. C., W. T. Abraham, N. M. Albert, K. Chiswell, W. G. Stough, M. Gheorghiade, B. Greenberg, et al. “ACC/AHA performance measures for patients hospitalized with HF: Are they predictive of clinical outcomes?.” In Journal of the American College of Cardiology, 47:255A-255A. ELSEVIER SCIENCE INC, 2006.
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  - Levine, G. N., Y. Lokhnygina, H. D. White, K. Chiswell, N. S. Kleiman, K. W. Mahaffey, D. C. Gulba, et al. “Percutaneous coronary intervention in patients receiving only a single subcutaneous dose of enoxaparin: Results from the SYNERGY trial.” In Journal of the American College of Cardiology, 47:228A-228A. ELSEVIER SCIENCE INC, 2006.
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  - Moser, D., K. Chiswell, L. Yamokoski, G. Conway, K. A. Hartman, C. Binanay, and L. W. Stevenson. “Lack of improvement in quality of life post-hospitalization predicts mortality in patients with advanced heart failure.” In Journal of the American College of Cardiology, 45:178A-178A. ELSEVIER SCIENCE INC, 2005.
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