Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.B.B.S., Tamilnadu Dr. M.G.R. Medical University 1997
• 

  Duke Appointment History

  • Assistant Professor of Anesthesiology, Anesthesiology, VA Anesthesiology Service, Anesthesiology 2012 - 2017
• Research
• 

  Selected Grants

  • Comparative effectiveness in Perioperative and Critical Care Medicine: Crystalloid Fluid Therapy awarded by Baxter Healthcare Corporation 2013 - 2014
• Publications & Artistic Works
• 

  Selected Publications

  • Journal Articles

    • Raghunathan, K, Layton, JB, Ohnuma, T, and Shaw, AD. "Observational Research Using Propensity Scores." Advances in chronic kidney disease 23, no. 6 (November 2016): 367-372. (Review)  Full Text  Open Access Copy
    • Stefan, MS, Hill, NS, Raghunathan, K, Liu, X, Pekow, PS, Memtsoudis, SG, Ramachandran, SK, and Lindenauer, PK. "Outcomes Associated with Early Postoperative Noninvasive Ventilation in Bariatric Surgical Patients with Sleep Apnea." Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 12, no. 11 (November 2016): 1507-1516.  Full Text
    • Guinn, NR, Waldron, NH, Cooter, ML, Goldberg, CL, Kertai, MD, Raghunathan, K, Bandarenko, N, Hoffman, M, and Bennett-Guerrero, E. "No association between donor age and recipient outcomes: transfusion of plasma in patients undergoing coronary artery bypass grafting surgery." Transfusion 56, no. 7 (July 2016): 1723-1729.  Full Text
    • Raghunathan, K, and Wang, XS. "In support of ‘usual’ perioperative care." British Journal of Anaesthesia 117, no. 1 (July 2016): 7-12.  Full Text  Open Access Copy
    • Barbeito, A, Raghunathan, K, and Albrecht, R. "Primus Inter Pares." Anesthesia and analgesia 122, no. 5 (May 2016): 1719-1720. (Letter)  Full Text
    • Barbeito, A, Guerri-Guttenberg, RA, Raghunathan, K, and Rao, S. "High-Velocity Jet in the Right Atrium: What Is the Diagnosis?." Anesthesia and analgesia 122, no. 3 (March 2016): 647-650.  Full Text
    • Conlin, F, Roy Connelly, N, Raghunathan, K, Friderici, J, and Schwabauer, A. "Focused Transthoracic Cardiac Ultrasound: A Survey of Training Practices." Journal of cardiothoracic and vascular anesthesia 30, no. 1 (January 2016): 102-106.  Full Text
    • Heath, M, Barbeito, A, Welsby, I, Maxwell, C, Iribarne, A, and Raghunathan, K. "Using Zero-Balance Ultrafiltration With Dialysate as a Replacement Solution for Toxin and Eptifibatide Removal on a Dialysis-Dependent Patient During Cardiopulmonary Bypass." Journal of cardiothoracic and vascular anesthesia 30, no. 1 (January 2016): 162-168.  Full Text
    • Thiele, RH, Raghunathan, K, Brudney, CS, Lobo, DN, Martin, D, Senagore, A, Cannesson, M, Gan, TJ, Mythen, MMG, Shaw, AD, Miller, TE, and Perioperative Quality Initiative (POQI) I Workgroup, . "American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative  (POQI) joint consensus statement on perioperative fluid management within an enhanced recovery pathway for colorectal surgery." Perioperative medicine (London, England) 5 (January 2016): 24-.  Full Text  Open Access Copy
    • McGee, WT, Raghunathan, K, and Adler, AC. "Utility of Functional Hemodynamics and Echocardiography to Aid Diagnosis and Management of Shock." Shock (Augusta, Ga.) 44, no. 6 (December 2015): 535-541. (Review)  Full Text
    • Raghunathan, K, Bonavia, A, Nathanson, BH, Beadles, CA, Shaw, AD, Brookhart, MA, Miller, TE, and Lindenauer, PK. "Association between Initial Fluid Choice and Subsequent In-hospital Mortality during the Resuscitation of Adults with Septic Shock." Anesthesiology 123, no. 6 (December 2015): 1385-1393.  Full Text  Open Access Copy
    • Raghunathan, K, Nailer, P, and Konoske, R. "What is the ideal crystalloid?." Current opinion in critical care 21, no. 4 (August 2015): 309-314. (Review)  Full Text
    • Raghunathan, K, Miller, TE, and Rashid, AM. "Confounders versus Mediators: An Important Distinction." Anesthesiology 123, no. 1 (July 2015): 234-. (Letter)  Full Text
    • Raghunathan, K, and Konoske, R. "The authors reply." Critical care medicine 43, no. 5 (May 2015): e156-. (Letter)  Full Text
    • Raghunathan, K, Singh, M, and Lobo, DN. "Fluid management in abdominal surgery: what, when, and when not to administer." Anesthesiology clinics 33, no. 1 (March 2015): 51-64. (Review)  Full Text
    • Krajewski, ML, Raghunathan, K, Paluszkiewicz, SM, Schermer, CR, and Shaw, AD. "Meta-analysis of high- versus low-chloride content in perioperative and critical care fluid resuscitation." The British journal of surgery 102, no. 1 (January 2015): 24-36. (Review)  Full Text
    • Raghunathan, K, Beadles, C, Nathanson, BH, and Lindenauer, PK. "The authors reply." Critical care medicine 43, no. 1 (January 2015): e27-e28. (Letter)  Full Text
    • Raghunathan, K, Murray, PT, Beattie, WS, Lobo, DN, Myburgh, J, Sladen, R, Kellum, JA, Mythen, MG, and Shaw, AD. "Choice of fluid in acute illness: what should be given? An international consensus." British journal of anaesthesia 114, no. 1 (January 2015): 175-.  Full Text
    • Beadles, C, Raghunathan, K, Nathanson, BH, and Lindenauer, PK. "The authors reply." Critical care medicine 42, no. 12 (December 2014): e796-e797. (Letter)  Full Text
    • Shaw, AD, Raghunathan, K, Peyerl, FW, Munson, SH, Paluszkiewicz, SM, and Schermer, CR. "Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS." Intensive care medicine 40, no. 12 (December 2014): 1897-1905.  Full Text
    • Raghunathan, K, Murray, PT, Beattie, WS, Lobo, DN, Myburgh, J, Sladen, R, Kellum, JA, Mythen, MG, Shaw, AD, and ADQI XII Investigators Group, . "Choice of fluid in acute illness: what should be given? An international consensus." British journal of anaesthesia 113, no. 5 (November 2014): 772-783. (Review)  Full Text
    • Heath, M, Raghunathan, K, Welsby, I, and Maxwell, C. "Using Zero Balance Ultrafiltration with Dialysate as a Replacement Fluid for Hyperkalemia during Cardiopulmonary Bypass." The Journal of Extra-corporeal Technology 46, no. 3 (September 2014): 262-266.
    • Miller, TE, Raghunathan, K, and Gan, TJ. "State-of-the-art fluid management in the operating room." Best practice & research. Clinical anaesthesiology 28, no. 3 (September 2014): 261-273. (Review)  Full Text  Open Access Copy
    • Raghunathan, K, Miller, TE, and Shaw, AD. "Intravenous starches: is suspension the best solution?." Anesthesia and analgesia 119, no. 3 (September 2014): 731-736.  Full Text  Open Access Copy
    • Raghunathan, K, Shaw, A, Nathanson, B, Stürmer, T, Brookhart, A, Stefan, MS, Setoguchi, S, Beadles, C, and Lindenauer, PK. "Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*." Critical care medicine 42, no. 7 (July 2014): 1585-1591.  Full Text
    • Raghunathan, K, Harris, PT, Spurbeck, RR, Arvidson, CG, and Arvidson, DN. "Crystal structure of an efficacious gonococcal adherence inhibitor: an enolase from Lactobacillus gasseri." FEBS letters 588, no. 14 (June 2014): 2212-2216.  Full Text
    • Miller, TE, Raghunathan, K, and Gan, TJ. "State-of-the-art fluid management in the operating room." Best Practice and Research: Clinical Anaesthesiology 28, no. 3 (2014): 261-273.  Full Text
    • Raghunathan, K, Shaw, A, Nathanson, B, Stürmer, T, Brookhart, A, Stefan, MS, Setoguchi, S, Beadles, C, and Lindenauer, PK. "Association between the choice of IV crystalloid and in-hospital mortality among critically Ill adults with sepsis." Critical Care Medicine 42, no. 7 (January 1, 2014): 1585-1591.  Full Text
    • Shaw, AD, Raghunathan, K, Peyerl, FW, Munson, SH, Paluszkiewicz, SM, and Schermer, CR. "Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS." Intensive Care Medicine 40, no. 12 (January 1, 2014): 1897-1905.  Full Text
    • Steingrub, JS, Lagu, T, Rothberg, MB, Nathanson, BH, Raghunathan, K, and Lindenauer, PK. "Treatment with neuromuscular blocking agents and the risk of in-hospital mortality among mechanically ventilated patients with severe sepsis." Critical Care Medicine 42, no. 1 (January 1, 2014): 90-96.  Full Text
    • Steingrub, JS, Lagu, T, Rothberg, MB, Nathanson, BH, Raghunathan, K, and Lindenauer, PK. "Treatment with neuromuscular blocking agents and the risk of in-hospital mortality among mechanically ventilated patients with severe sepsis." Crit Care Med 42, no. 1 (January 2014): 90-96.  Full Text  Link to Item
    • Adler, AC, Nathanson, BH, Raghunathan, K, and McGee, WT. "Effects of body surface area-indexed calculations in the morbidly obese: A mathematical analysis." Journal of Cardiothoracic and Vascular Anesthesia 27, no. 6 (December 1, 2013): 1140-1144.  Full Text
    • Adler, AC, Nathanson, BH, Raghunathan, K, and McGee, WT. "Effects of body surface area-indexed calculations in the morbidly obese: a mathematical analysis." J Cardiothorac Vasc Anesth 27, no. 6 (December 2013): 1140-1144.  Full Text  Link to Item
    • Karakala, N, Raghunathan, K, and Shaw, AD. "Intravenous fluids in sepsis: what to use and what to avoid." Curr Opin Crit Care 19, no. 6 (December 2013): 537-543. (Review)  Full Text  Link to Item
    • McGee, WT, and Raghunathan, K. "Physiologic goal-directed therapy in the perioperative period: The volume prescription for high-risk patients." Journal of Cardiothoracic and Vascular Anesthesia 27, no. 6 (December 1, 2013): 1079-1086.  Full Text
    • McGee, WT, and Raghunathan, K. "Physiologic goal-directed therapy in the perioperative period: the volume prescription for high-risk patients." J Cardiothorac Vasc Anesth 27, no. 6 (December 2013): 1079-1086. (Review)  Full Text  Link to Item
    • Raghunathan, K, Barbeito, A, and MacLeod, D. "Goal-directed advanced cardiac life support: coronary perfusion pressure as a target during resuscitation." Crit Care Med 41, no. 12 (December 2013): 2817-2818.  Full Text  Link to Item
    • Karakala, N, Raghunathan, K, and Shaw, AD. "Intravenous fluids in sepsis: What to use and what to avoid (Accepted)." Current Opinion in Critical Care (November 19, 2013).  Full Text
    • Marik, PE, Raghunathan, K, and Bloomstone, J. "Rebuttal from Dr Marik et al." Chest 144, no. 2 (August 2013): 379-380.  Full Text  Link to Item
    • Marik, PE, Raghunathan, K, and Bloomstone, J. "Counterpoint: Are the best patient outcomes achieved when ICU bundles are rigorously adhered to? No." Chest 144, no. 2 (August 2013): 374-378.  Full Text  Link to Item
    • Raghunathan, K, Shaw, AD, and Bagshaw, SM. "Fluids are drugs: type, dose and toxicity." Curr Opin Crit Care 19, no. 4 (August 2013): 290-298. (Review)  Full Text  Link to Item
    • Adler, AC, Connelly, NR, Ankam, A, and Raghunathan, K. "Technical communication: inhaled anesthetic agent-vaporizer mismatch: management in settings with limited resources: don't try this at home." Anesth Analg 116, no. 6 (June 2013): 1272-1275.  Full Text  Link to Item
    • Shaw, A, and Raghunathan, K. "Fluid management in cardiac surgery: colloid or crystalloid?." Anesthesiol Clin 31, no. 2 (June 2013): 269-280. (Review)  Full Text  Link to Item
    • Raghunathan, K, Connelly, NR, Friderici, J, Naglieri-Prescod, D, Joyce, R, Prasanna, P, and Ponnusamy, N. "Unwarranted variability in antibiotic prophylaxis for cesarean section delivery: a national survey of anesthesiologists." Anesth Analg 116, no. 3 (March 2013): 644-648.  Full Text  Link to Item
    • Adler, AC, Connelly, NR, Ankam, A, and Raghunathan, K. "Inhaled anesthetic agent-vaporizer mismatch: Management in settings with limited resources: Don't try this at home." Anesthesia and Analgesia 116, no. 6 (2013): 1272-1275.  Full Text
    • Raghunathan, K, and Pyati, S. "Persistent postsurgical pain--need for better methods." Reg Anesth Pain Med 38, no. 1 (January 2013): 73-74. (Letter)  Full Text  Link to Item
    • Raghunathan, K, and Shaw, A. "Hydroxyethyl starch or saline in intensive care [4]." New England Journal of Medicine 368, no. 8 (2013): 774-775.  Full Text
    • Adler, AC, Nathanson, BH, Raghunathan, K, and McGee, WT. "Indexed hemodynamic measurements may be inappropriate at body surface area extremes." Critical Care 16, no. 5 (2012).  Full Text
    • Adler, AC, Nathanson, BH, Raghunathan, K, and McGee, WT. "Misleading indexed hemodynamic parameters: The clinical importance of discordant BMI and BSA at extremes of weight." Critical Care 16, no. 6 (2012).  Full Text
    • Bloomstone, JA, Raghunathan, K, and McGee, WT. "Why the gray zone may shift within the fog." Anesthesiology 116, no. 3 (2012): 739-740.  Full Text
    • Raghunathan, K, Bloomstone, JA, and McGee, WT. "Cardiac output measured with both esophageal doppler device and vigileo-flotrac device." Anesthesia and Analgesia 114, no. 5 (2012): 1141-1142.  Full Text
    • Raghunathan, K, McGee, WT, and Higgins, T. "Importance of intravenous fluid dose and composition in surgical ICU patients." Current Opinion in Critical Care 18, no. 4 (2012): 350-357.  Full Text
    • Raghunathan, K. "Checklists, safety, my culture and me." BMJ Quality and Safety 21, no. 7 (2012): 617-620.  Full Text
    • Connelly, NR, Freiman, JP, Lucas, T, Parker, RK, Raghunathan, K, Gibson, C, Katz, B, and Iwashita, C. "Addition of epinephrine to epidural bupivacaine infusions following initiation of labor analgesia with epidural fentanyl." Journal of Clinical Anesthesia 23, no. 4 (2011): 265-269.  Full Text
    • Malik, A, Jenkins, ER, Raghunathan, K, and Connelly, NR. "General anesthesia is not defined by a BIS level." Journal of Clinical Anesthesia 23, no. 1 (2011): 79-80.  Full Text
    • Raghunathan, K, Al-Najjar, H, and Snavely, A. "Control charts and control limits." Anesthesia and Analgesia 112, no. 3 (2011): 736-737.  Full Text
    • Raghunathan, K, Connelly, NR, and Kanter, GJ. "ε-aminocaproic acid and clinical value in cardiac anesthesia." Journal of Cardiothoracic and Vascular Anesthesia 25, no. 1 (2011): 16-19.  Full Text
    • Connelly, NR, and Raghunathan, K. "The value of the P-value." Journal of Clinical Anesthesia 22, no. 2 (2010): 154-155.  Full Text
    • Raghunathan, K, Connelly, NR, Robbins, LD, Ganim, R, Hochheiser, G, and DiCampli, R. "Inhaled Epoprostenol During One-Lung Ventilation." Annals of Thoracic Surgery 89, no. 3 (2010): 981-983.  Full Text
    • Schwartz, DA, Raghunathan, K, and Connelly, NR. "Reply to 'Successful resuscitation of bupivacaine-induced cardiotoxicity in a neonate'." Paediatric Anaesthesia 20, no. 12 (2010): 1136-1137.  Full Text
    • Reuben, SS, Buvenandran, A, Kroin, JS, and Raghunathan, K. "Erratum: Analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery (Anesthesiology (2006) 105 (A1194))." Anesthesiology 110, no. 3 (March 1, 2009): 689-.  Full Text
    • Connelly, NR, Raghunathan, K, Zuegge, KL, and Lucas, T. "Maternal hemodynamic monitoring and the vigileo monitor." Anesthesiology 111, no. 1 (2009): 211-212.  Full Text
    • Schwartz, D, and Raghunathan, K. "Difficult venous access." Paediatric Anaesthesia 19, no. 1 (2009): 60--.  Full Text
    • Schwartz, D, and Raghunathan, K. "Anesthesia and mitochondrial disorders." Paediatric Anaesthesia 19, no. 1 (2009): 60-61.  Full Text
    • Raghunathan, K, Schwartz, D, and Connelly, NR. "Determining the accuracy of caudal needle placement in children: A comparison of the swoosh test and ultrasonography (Pediatric Anesthesia (2008) 18, (606-612))." Paediatric Anaesthesia 18, no. 11 (2008): 1147--.  Full Text
    • Raghunathan, K, Schwartz, D, and Connelly, NR. "Determining the accuracy of caudal needle placement in children: A comparison of the swoosh test and ultrasonography." Paediatric Anaesthesia 18, no. 7 (2008): 606-612.  Full Text
    • Schwartz, D, Raghunathan, K, Dunn, S, and Connelly, NR. "Ultrasonography and pediatric caudals." Anesthesia and Analgesia 106, no. 1 (2008): 97-99.  Full Text
    • Schwartz, D, and Raghunathan, K. "Reply." Paediatric Anaesthesia 18, no. 4 (2008): 334-335.  Full Text
    • Connelly, NR, and Raghunathan, K. "Commentary." Journal of Clinical Anesthesia 19, no. 8 (2007): 639-641.  Full Text
    • Liang, BA, Connelly, CBNR, and Raghunathan, K. "To tell the truth: potential liability for concealing physician impairment." Journal of Clinical Anesthesia 19, no. 8 (2007): 638-641.  Full Text
    • Schwartz, D, Raghunathan, K, and Han, D. "The 'Doppler-swoosh' test: A further modification to the 'swoosh' test [4]." Paediatric Anaesthesia 17, no. 6 (2007): 600-601.  Full Text
    • Reuben, SS, Buvanendran, A, Kroin, JS, and Raghunathan, K. "The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery (Retraction in: Anesthesia and Analgesia (2009) 108:4 (1350))." Anesthesia and Analgesia 103, no. 5 (2006): 1271-1277.  Full Text
    • Reuben, SS, Ekman, EF, Raghunathan, K, Steinberg, RB, Blinder, JL, and Adesioye, J. "The effect of cyclooxygenase-2 inhibition on acute and chronic donor-site pain after spinal-fusion surgery (Retraction in: Regional Anesthesia and Pain Medicine (2009) 34:2 (184))." Regional Anesthesia and Pain Medicine 31, no. 1 (2006): 6-13.  Full Text
    • Reuben, SS, Raghunathan, K, and Roissing, S. "Evaluating the analgesic effect of the perioperative perineural infiltration of bupivacaine and clonidine at the site of injury following lower extremity amputation." Acute Pain 8, no. 3 (2006): 117-123.  Full Text

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