Overview
Katherine Martucci Ph.D. is a neuroscientist who specializes in human clinical research of chronic pain, reward and motivation behaviors, sensory and acute pain perception, and opioid use and addiction. Dr. Martucci serves as Director of the Human Affect and Pain Neuroscience Lab which uses a combination of neuroimaging techniques, including functional magnetic resonance imaging (fMRI) of the brain and cervical spinal cord, as well as sensory, behavioral and psychological tests to study acute and chronic pain in humans.
As part of the Center for Translational Pain Medicine (CTPM), Dr. Martucci’s lab is part of Duke University’s Department of Anesthesiology, conducting research in collaboration with the Brain Imaging and Analysis Center (BIAC) and Duke Institute for Brain Sciences (DIBS).
Dr. Martucci earned her Ph.D. in Neurobiology and Anatomy at Wake Forest School of Medicine and continued her training in clinical research with a postdoctoral fellowship at Stanford University. While at Stanford, Dr. Martucci obtained a prestigious NIH K99 “Pathway to Independence Award”. Since joining Duke University in 2018, Dr. Martucci has acquired funding via multiple NIH grants to continue her line of neuroimaging clinical research of the central nervous system in chronic pain.
Current Appointments & Affiliations
Recent Publications
Nociplasticity: A Proposed Concept to Understand the Symptomatology of Systemic Lupus Erythematosus.
Journal Article Arthritis Rheumatol · March 10, 2025 Full text Link to item CiteEPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data.
Journal Article bioRxiv · January 27, 2025 Functional magnetic resonance imaging (fMRI) of the spinal cord is relevant for studying sensation, movement, and autonomic function. Preprocessing of spinal cord fMRI data involves segmentation of the spinal cord on gradient-echo echo planar imaging (EPI) ... Full text Link to item CiteENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain.
Journal Article Pain · December 1, 2024 Full text Link to item CiteRecent Grants
Neural correlates and behavioral impact of withdrawal-induced hyperalgesia among people who smoke with and without chronic pain
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2030Predictors of Pain Severity and Pain-Related Outcomes in Individuals with Sickle Cell Disease
ResearchConsultant · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2028Neurobiological Effects of Long-Term Opioid Therapy in the Brain and Spinal Cord
ResearchPrincipal Investigator · Awarded by National Institute on Drug Abuse · 2022 - 2027View All Grants