Katherine Martucci | Scholars@Duke

Katherine Martucci
Assistant Professor in Anesthesiology

Katherine Martucci Ph.D. is a neuroscientist who specializes in human clinical research of chronic pain, reward and motivation behaviors, sensory and acute pain perception, and opioid use and addiction. Dr. Martucci serves as Director of the Human Affect and Pain Neuroscience Lab which uses a combination of neuroimaging techniques, including functional magnetic resonance imaging (fMRI) of the brain and cervical spinal cord, as well as sensory, behavioral and psychological tests to study acute and chronic pain in humans.

As part of the Center for Translational Pain Medicine (CTPM) at Duke, Dr. Martucci’s lab is in the Department of Anesthesiology and conducts research in collaboration with the Brain Imaging and Analysis Center (BIAC) and Duke Institute for Brain Sciences (DIBS).

Dr. Martucci earned her Ph.D. in Neurobiology and Anatomy at Wake Forest School of Medicine and continued her training in clinical research with a postdoctoral fellowship at Stanford University. While at Stanford Dr. Martucci obtained a prestigious NIH K99 “Pathway to Independence Award” and launched her research program in human neuroscience of pain, reward, opioids, and addiction. At the start of her scientific career at Duke, Dr. Martucci obtained a NIH R00 “Transition to Independence Award” to conduct the first longitudinal neuroimaging clinical research study of how opioid medications affect the central nervous system in individuals with fibromyalgia. Dr. Martucci is passionate about providing new scientific knowledge related to chronic pain and opioid use and how these factors together influence central nervous system function and symptoms in individuals with chronic pain.

Current Appointments & Affiliations

Assistant Professor in Anesthesiology, Anesthesiology, Clinical Science Departments 2018
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2018

Contact Information

3 Genome Ct, Rm. #6134, Durham, NC 27710
DUMC 3094, Durham, NC 27710
katherine.martucci@duke.edu (919) 613-8023
@DrKatieMartucci
Dr. Katherine Martucci's LinkedIn
Duke Center for Translational Pain Medicine
Lab Website

Background
Education, Training, & Certifications
- Ph.D., Wake Forest University School Of Medicine 2011
- B.S., University of Connecticut 2005
Leadership & Clinical Positions at Duke
- Director, Human Affect and Pain Neuroscience Laboratory
Academic Positions Outside Duke
- Postdoctoral Scholar, Stanford University. 2012 - 2018
Recognition
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- The Impact of Opioids on Chronic Pain: Clinical Research and Career Training in Spinal Cord fMRI and Brain Reward Systems awarded by National Institutes of Health 2018 - 2021
Fellowships, Supported Research, & Other Grants
- NIH Pathway to Independence Award (K99/R00) awarded by NIH NIDA 2015 - 2018
- NIH Loan Repayment Program in Clinical Research awarded by NIH LRP 2014 - 2016
- NIH Institutional Postdoctoral Anesthesia Training Program in Biomedical Research (T32) awarded by NIH NIGMS 2013 - 2015
- NIH Individual Predoctoral Ruth L. Kirschstein National Research Service Award (F31) awarded by NIH NIDA 2010 - 2012
- NIH Institutional Predoctoral Neurobiology and Anatomy Sensory Training Grant (T31) awarded by NIH NINDS 2007 - 2009
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Clemens, JQ, Mullins, C, Ackerman, AL, Bavendam, T, van Bokhoven, A, Ellingson, BM, Harte, SE, Kutch, JJ, Lai, HH, Martucci, KT, Moldwin, R, Naliboff, BD, Pontari, MA, Sutcliffe, S, Landis, JR, and MAPP Research Network Study Group, . "Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network." Nature Reviews. Urology 16, no. 3 (March 2019): 187-200. (Review) Full Text
  - Martucci, KT, Weber, KA, and Mackey, SC. "Altered Cervical Spinal Cord Resting-State Activity in Fibromyalgia." Arthritis & Rheumatology (Hoboken, N.J.) 71, no. 3 (March 2019): 441-450. Full Text
  - Martucci, KT, Borg, N, MacNiven, KH, Knutson, B, and Mackey, SC. "Altered prefrontal correlates of monetary anticipation and outcome in chronic pain." Pain 159, no. 8 (August 2018): 1494-1507. Full Text
  - Martucci, KT, and MacKey, SC. "Neuroimaging of Pain: Human Evidence and Clinical Relevance of Central Nervous System Processes and Modulation." Anesthesiology 128, no. 6 (June 1, 2018): 1241-1254. (Review) Full Text
  - Kutch, JJ, Ichesco, E, Hampson, JP, Labus, JS, Farmer, MA, Martucci, KT, Ness, TJ, Deutsch, G, Apkarian, AV, Mackey, SC, Klumpp, DJ, Schaeffer, AJ, Rodriguez, LV, Kreder, KJ, Buchwald, D, Andriole, GL, Lai, HH, Mullins, C, Kusek, JW, Landis, JR, Mayer, EA, Clemens, JQ, Clauw, DJ, Harris, RE, and MAPP Research Network, . "Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study." Pain 158, no. 10 (October 2017): 1979-1991. Full Text
  - Kutch, JJ, Labus, JS, Harris, RE, Martucci, KT, Farmer, MA, Fenske, S, Fling, C, Ichesco, E, Peltier, S, Petre, B, Guo, W, Hou, X, Stephens, AJ, Mullins, C, Clauw, DJ, Mackey, SC, Apkarian, AV, Landis, JR, Mayer, EA, and MAPP Research Network, . "Resting-state functional connectivity predicts longitudinal pain symptom change in urologic chronic pelvic pain syndrome: a MAPP network study." Pain 158, no. 6 (June 2017): 1069-1082. Full Text
  - Martucci, KT. "Disentangling mood and pain: a commentary on 2 manuscripts." Pain 158, no. 1 (January 2017): 4-5. Full Text
  - Huang, L, Kutch, JJ, Ellingson, BM, Martucci, KT, Harris, RE, Clauw, DJ, Mackey, S, Mayer, EA, Schaeffer, AJ, Apkarian, AV, and Farmer, MA. "Brain white matter changes associated with urological chronic pelvic pain syndrome: multisite neuroimaging from a MAPP case-control study." Pain 157, no. 12 (December 2016): 2782-2791. Full Text
  - Martucci, KT, and Mackey, SC. "Imaging Pain." Anesthesiology Clinics 34, no. 2 (June 2016): 255-269. (Review) Full Text
  - Martucci, KT, Shirer, WR, Bagarinao, E, Johnson, KA, Farmer, MA, Labus, JS, Apkarian, AV, Deutsch, G, Harris, RE, Mayer, EA, Clauw, DJ, Greicius, MD, and Mackey, SC. "The posterior medial cortex in urologic chronic pelvic pain syndrome: detachment from default mode network-a resting-state study from the MAPP Research Network." Pain 156, no. 9 (September 2015): 1755-1764. Full Text
  - Farmer, MA, Huang, L, Martucci, K, Yang, CC, Maravilla, KR, Harris, RE, Clauw, DJ, Mackey, S, Ellingson, BM, Mayer, EA, Schaeffer, AJ, Apkarian, AV, and MAPP Research Network, . "Brain White Matter Abnormalities in Female Interstitial Cystitis/Bladder Pain Syndrome: A MAPP Network Neuroimaging Study." The Journal of Urology 194, no. 1 (July 2015): 118-126. Full Text
  - Kairys, AE, Schmidt-Wilcke, T, Puiu, T, Ichesco, E, Labus, JS, Martucci, K, Farmer, MA, Ness, TJ, Deutsch, G, Mayer, EA, Mackey, S, Apkarian, AV, Maravilla, K, Clauw, DJ, and Harris, RE. "Increased brain gray matter in the primary somatosensory cortex is associated with increased pain and mood disturbance in patients with interstitial cystitis/painful bladder syndrome." The Journal of Urology 193, no. 1 (January 2015): 131-137. Full Text
  - Bagarinao, E, Johnson, KA, Martucci, KT, Ichesco, E, Farmer, MA, Labus, J, Ness, TJ, Harris, R, Deutsch, G, Apkarian, AV, Mayer, EA, Clauw, DJ, and Mackey, S. "Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study." Pain 155, no. 12 (December 2014): 2502-2509. Full Text
  - Nahman-Averbuch, H, Martucci, KT, Granovsky, Y, Weissman-Fogel, I, Yarnitsky, D, and Coghill, RC. "Distinct brain mechanisms support spatial vs temporal filtering of nociceptive information." Pain 155, no. 12 (December 2014): 2491-2501. Full Text
  - Kilpatrick, LA, Kutch, JJ, Tillisch, K, Naliboff, BD, Labus, JS, Jiang, Z, Farmer, MA, Apkarian, AV, Mackey, S, Martucci, KT, Clauw, DJ, Harris, RE, Deutsch, G, Ness, TJ, Yang, CC, Maravilla, K, Mullins, C, and Mayer, EA. "Alterations in resting state oscillations and connectivity in sensory and motor networks in women with interstitial cystitis/painful bladder syndrome." The Journal of Urology 192, no. 3 (September 2014): 947-955. Full Text
  - Zeidan, F, Martucci, KT, Kraft, RA, McHaffie, JG, and Coghill, RC. "Neural correlates of mindfulness meditation-related anxiety relief." Social Cognitive and Affective Neuroscience 9, no. 6 (June 2014): 751-759. Full Text
  - Emerson, NM, Zeidan, F, Lobanov, OV, Hadsel, MS, Martucci, KT, Quevedo, AS, Starr, CJ, Nahman-Averbuch, H, Weissman-Fogel, I, Granovsky, Y, Yarnitsky, D, and Coghill, RC. "Pain sensitivity is inversely related to regional grey matter density in the brain." Pain 155, no. 3 (March 2014): 566-573. Full Text
  - Martucci, KT, Ng, P, and MacKey, S. "Neuroimaging chronic pain: What have we learned and where are we going?." Future Neurology 9, no. 6 (January 1, 2014): 615-626. (Review) Full Text
  - Martucci, KT, Eisenach, JC, Tong, C, and Coghill, RC. "Opioid-independent mechanisms supporting offset analgesia and temporal sharpening of nociceptive information." Pain 153, no. 6 (June 2012): 1232-1243. Full Text
  - Martucci, KT, Yelle, MD, and Coghill, RC. "Differential effects of experimental central sensitization on the time-course and magnitude of offset analgesia." Pain 153, no. 2 (February 2012): 463-472. Full Text
  - Zeidan, F, Martucci, KT, Kraft, RA, Gordon, NS, McHaffie, JG, and Coghill, RC. "Brain mechanisms supporting the modulation of pain by mindfulness meditation." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 31, no. 14 (April 2011): 5540-5548. Full Text
  - Martucci, KT, and Coghill, RC. "Regional anesthesia: Functional implications beyond the anesthetized nerve." Anesthesiology 114, no. 1 (January 1, 2011): 21-23. (Review) Full Text
- Conference Papers
  - Jarrahi, B, Martucci, KT, Nilakantan, AS, and Mackey, S. "Cold Water Pressor Test Differentially Modulates Functional Network Connectivity in Fibromyalgia Patients Compared with Healthy Controls." July 2018. Full Text
  - Jarrahi, B, Martucci, KT, Nilakantan, AS, and Mackey, S. "Investigating the BOLD spectral power of the intrinsic connectivity networks in fibromyalgia patients: A resting-state fMRI study." July 2017. Full Text
Teaching & Mentoring
Advising & Mentoring
- Research Mentorship
  
  Research Assistants / Research Coordinators
  2012-2014 Aneesha Nilakantan as a research coordinator, now Neuroscience PhD student, Northwestern University
  2013 - 2015 Amy Sentis as a research coordinator, now MD/PhD candidate at the University of Pittsburgh
  2014 - 2015 Lauren Foster as a research coordinator, now in Stanford Cancer Clinical Trials Office
  2016 Christina Cojocaru as a research coordinator, now a Medical Student at Midwestern University
  
  Undergraduate Student Research Assistants
  2012 Safwan Siddiqui as a sophomore Stanford undergraduate, now at Shockwave Medical
  2012 Emily Marx as a junior Stanford undergraduate, now Software Test Engineer at Illumina
  2014 - 2016 Marisa Borja as a sophomore - junior Stanford undergraduate, now at Biosense Webster
  2016 Erin Perrine as senior Stanford undergraduate, now intern at Google
  2017 Elizabeth Cha as a sophomore University of Rochester undergraduate
  2017 Grace Kim as a freshman Stanford undergraduate
  2017 Andrew Bassilakis as a junior Stanford undergraduate
  2018 Leah Tolby as a freshman Stanford undergraduate
  2019- Meghna Nanda as a Duke undergraduate
  2019-Vinny Krishna as a Duke undergraduate
Available to mentor:
- Post-Doc
- Undergraduate
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
Service to the Profession

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

Awards & Honors

Subject Headings

Selected Grants

Fellowships, Supported Research, & Other Grants

Selected Publications

Academic Articles

Conference Papers

Advising & Mentoring

Available to mentor:

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession