Overview
Biological molecules can unlock and harness the special chemical power of metal ions, while also maintaining control of metal homeostasis. The Haas Lab investigates the interactions between metal ions and polypeptides, with a focus on the proteins that harness copper redox chemistry in human extracellular fluids and at membrane interfaces.
Current Duke Appointments & Affiliations
Associate Professor of the Practice of Chemistry
·
2021 - Present
Chemistry,
Trinity College of Arts & Sciences
Recent Scholarly Works
A Flexible Framework for Course-Based Undergraduate Research Experiences
Preprint · September 29, 2026 Course-based undergraduate research experiences (CUREs) broaden access to the high-impact practice of undergraduate research. Unfortunately, many faculty lack a clear roadmap for developing a CURE. To address this barrier, we present a series of mo ... Full text CiteCu(I) and Cu(II) binding by hyperactive variants of the human CTR1 N-terminus: Insights from cellular and model peptide studies.
Journal article Journal of inorganic biochemistry · September 2026 Featured Work Copper (Cu) trafficking requires precise control of Cu(II)/Cu(I) redox chemistry to enable cellular acquisition while preventing toxicity. Human Cu transporter 1 protein (hCTR1) mediates cellular Cu uptake, yet key molecular details governing its extracell ... Full text Open Access CiteA Flexible Framework for Course-Based Undergraduate Research Experiences in Advanced Chemistry Laboratory Courses
Preprint · August 26, 2026 Course-based undergraduate research experiences (CUREs) broaden access to the high-impact practice of undergraduate research, but even faculty experienced in mentoring undergraduate researchers may lack a clear roadmap for translating that research ... Full text CiteRecent Grants
Communicating Science: 12 Profound Scientific Breakthroughs
ResearchPrincipal Investigator · Awarded by Research Corporation for Science Advancement · 2022 - 2025MRI: Acquisition of a Microscale Thermophoresis System
EquipmentMajor User · Awarded by National Science Foundation · 2022 - 2025Transporting Cu(I) as Cargo and Using Cu(III) as a Killer Cofactor: Histidine-rich Motifs in Ctr1 and Histatin 5 Control Cu Oxidation State and Reactivity
ResearchPrincipal Investigator · Awarded by Research Corporation for Science Advancement · 2021 - 2024View All Grants
Education
Duke University ·
2010
Ph.D.