Scholars@Duke
Kathryn Pax Lattimore Moore

Kathryn Pax Lattimore Moore

Assistant Professor of Neurology
Neurology, Movement Disorders
kathryn.p.moore@duke.edu
Box 3333 Med Ctr, Durham, NC 27710
932 Morreene Road, Durham, NC 27705

Selected Publications

Responsive Versus Continuous Deep Brain Stimulation for Speech in Essential Tremor: A Pilot Study.

Journal Article Mov Disord · September 2024 BACKGROUND: Responsive deep brain stimulation (rDBS) uses physiological signals to deliver stimulation when needed. rDBS is hypothesized to reduce stimulation-induced speech effects associated with continuous DBS (cDBS) in patients with essential tremor (E ... Full text Link to item Cite

Characterizing differences in retinal and choroidal microvasculature and structure in individuals with Huntington's Disease compared to healthy controls: A cross-sectional prospective study.

Journal Article PLoS One · 2024 OBJECTIVE: To characterize retinal and choroidal microvascular and structural changes in patients who are gene positive for mutant huntingtin protein (mHtt) with symptoms of Huntington's Disease (HD). METHODS: This study is a cross-sectional comparison of ... Full text Link to item Cite

Longitudinal Analysis of Retinal Microvascular and Choroidal Imaging Parameters in Parkinson's Disease Compared with Controls.

Journal Article Ophthalmol Sci · December 2023 PURPOSE: To quantify rate of change of retinal microvascular and choroidal structural parameters in subjects with Parkinson's disease (PD) compared with controls using OCT and OCT angiography (OCTA). DESIGN: Prospective longitudinal study. PARTICIPANTS: Se ... Full text Link to item Cite

Intrasession Repeatability of OCT Angiography Parameters in Neurodegenerative Disease.

Journal Article Ophthalmol Sci · June 2023 PURPOSE: To assess the intrasession repeatability of macular OCT angiography (OCTA) parameters in Alzheimer's disease (AD), mild cognitive impairment (MCI), Parkinson's disease (PD), and normal cognition (NC). DESIGN: Cross sectional study. SUBJECTS: Patie ... Full text Open Access Link to item Cite

A randomized clinical trial of burst vs. spaced physical therapy for Parkinsons disease.

Journal Article Parkinsonism Relat Disord · April 2022 INTRODUCTION: The optimal timing for physical therapy (PT) delivery in Parkinson's disease (PD) is unknown. Our objective was to determine whether spacing physical therapy visits over a longer period of time is beneficial for maintenance of physical functi ... Full text Link to item Cite

Frequency of suicidal ideation and associated clinical features in Lewy body dementia.

Journal Article Parkinsonism Relat Disord · September 2021 INTRODUCTION: Neuropsychiatric disturbance is common in individuals with Lewy body dementia (LBD). Despite this, there is minimal research regarding suicide risks in this population. METHODS: This study was a retrospective review of a prospectively-collect ... Full text Open Access Link to item Cite

Long-term clinical outcomes of bilateral GPi deep brain stimulation in advanced Parkinson's disease: 5 years and beyond.

Journal Article J Neurosurg · August 1, 2021 OBJECTIVE: Few studies have reported long-term outcomes of globus pallidus internus (GPi) deep brain stimulation (DBS) in Parkinson's disease (PD). The authors aimed to investigate long-term outcomes of bilateral GPi DBS for 5 years and beyond for PD patie ... Full text Link to item Cite

Globus Pallidus Internus (GPi) Deep Brain Stimulation for Parkinson's Disease: Expert Review and Commentary.

Journal Article Neurol Ther · June 2021 INTRODUCTION: The globus pallidus internus (GPi) region has evolved as a potential target for deep brain stimulation (DBS) in Parkinson's disease (PD). DBS of the GPi (GPi DBS) is an established, safe and effective method for addressing many of the motor s ... Full text Link to item Cite

Response to Telemedicine Visits From Patients With Parkinsonism During the COVID-19 Pandemic on Postvisit Surveys.

Journal Article J Patient Exp · 2021 Parkinson's disease and parkinsonism are common chronic neurodegenerative disorders that tend to affect older adults and cause physical and sometimes cognitive limitations. Given that these limitations could impact successful telemedicine use, we aimed to ... Full text Link to item Cite

Safety and Tolerability of Burst-Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson's Disease.

Journal Article Front Hum Neurosci · 2021 Background: Freezing of gait (FOG) is a common symptom in Parkinson's disease (PD) and can be difficult to treat with dopaminergic medications or with deep brain stimulation (DBS). Novel stimulation paradigms have been proposed to address suboptimal respon ... Full text Link to item Cite

Geospatial Analysis of Persons with Movement Disorders Living in Underserved Regions.

Journal Article Tremor Other Hyperkinet Mov (N Y) · 2021 BACKGROUND: Movement disorders persons from underserved areas have increased barriers to access tertiary care. There is currently limited data on the geographic and demographic profile of movement disorders persons from underserved areas. METHODS: A retros ... Full text Link to item Cite

Parkinson's disease motor subtypes and bilateral GPi deep brain stimulation: One-year outcomes.

Journal Article Parkinsonism Relat Disord · June 2020 OBJECTIVE: We aimed to explore the differences in motor symptoms and quality of life (QOL) outcomes following bilateral globus pallidus internus deep brain stimulation (GPi DBS), across well-defined motor subtypes of Parkinson's disease (PD), to improve cl ... Full text Link to item Cite

Physical activity mediates the association between striatal dopamine transporter availability and cognition in Parkinson's disease.

Journal Article Parkinsonism Relat Disord · May 2019 OBJECTIVE: Associations between cognition and nigrostriatal dopaminergic deficits in Parkinson's disease have been documented in the literature, but are incompletely understood. Here we studied the extent to which physical activity mediates the relationshi ... Full text Link to item Cite