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Kayla Kilpatrick

Biostatistician III
Biostatistics & Bioinformatics
2424 Erwin Rd Ste 1105, Hock Plaza, Durham, NC 27705

Selected Publications


Impact of Prognostic Notifications on Inpatient Advance Care Planning: A Cluster Randomized Trial.

Journal Article J Pain Symptom Manage · December 2025 BACKGROUND: A poor prognosis is an important trigger for advance care planning (ACP) conversations, but clinicians often overestimate prognosis. OBJECTIVE: To determine whether ACP note documentation increases by notifying inpatient physicians that a patie ... Full text Link to item Cite

Reporting the Degree of Certainty of CSF-Venous Fistulas in Patients with Spontaneous Intracranial Hypotension: The Duke CSF-Venous Fistula Confidence Score.

Journal Article AJNR Am J Neuroradiol · November 3, 2025 BACKGROUND AND PURPOSE: CSF-venous fistulas (CVFs) are a common cause of spontaneous intracranial hypotension (SIH). CVF identification and localization are critical for diagnosis and treatment, but inconsistent visualization of CVFs on myelography leads t ... Full text Link to item Cite

Investigating themes in hearing quality of life with user-nominated goals on the Glasgow Hearing Aid Benefit Profile (GHABP).

Journal Article J Patient Rep Outcomes · July 1, 2025 BACKGROUND: The Glasgow Hearing Aid Benefit Profile (GHABP) is a patient-reported outcome measure (PROM) that was developed for the assessment of hearing aid efficacy using standard goals and user-nominated goals. The objective of this study was to describ ... Full text Link to item Cite

G‐Estimation With Partial Interference

Journal Article Stat · June 2025 ABSTRACTIn the study of infectious disease interventions, one individual's treatment may affect another individual's outcome; that is, there may be interference. In this paper, methods are developed to draw inference about ... Full text Cite

A Cross-Biomeasure Study to Optimize Antiretroviral Adherence Estimation.

Journal Article Journal of acquired immune deficiency syndromes (1999) · March 2025 BackgroundIncomplete adherence to daily tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) reduces effectiveness. Adherence biomeasures (ie, drug concentrations in biological specimen) are more accurate than self-report. TDF/FTC's intracellular ... Full text Cite

Opportunity Cost of Surgical Management of Craniomaxillofacial Trauma: A Longitudinal Study.

Journal Article Craniomaxillofacial trauma & reconstruction · December 2024 Study designSingle-institution retrospective financial analysis.ObjectiveTrauma care is consistently linked to inadequate reimbursement, posing a significant financial burden for large trauma centers. Data show that declining Medicare rei ... Full text Open Access Cite

G-formula for observational studies under stratified interference, with application to bed net use on malaria.

Journal Article Statistics in medicine · July 2024 Assessing population-level effects of vaccines and other infectious disease prevention measures is important to the field of public health. In infectious disease studies, one person's treatment may affect another individual's outcome, that is, there may be ... Full text Cite

Predictors of Non-Rhinogenic Facial Pain or Pressure in Otolaryngology Clinic.

Journal Article Otolaryngol Head Neck Surg · May 2024 OBJECTIVES: Identify demographic and clinical characteristics that may help differentiate non-rhinogenic facial pain or pressure (NRFP) from sinusitis. STUDY DESIGN: Retrospective single-institution study. SETTING: Tertiary Care Center Rhinology Clinic. ME ... Full text Link to item Cite

Predictive Factors in Identifying Pediatric Patients at Risk of Diagnostically Limited Videofluoroscopic Swallow Studies.

Journal Article Ear Nose Throat J · October 26, 2023 Objective: Videofluoroscopic swallow studies (VFSS) are highly effective in characterizing pediatric dysphagia, but they are time- and resource-intensive, and necessitate the use of radiation. Identifying patients unlikely to benefit from VFSS is crucial t ... Full text Link to item Cite

Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral Therapy.

Journal Article The Journal of infectious diseases · July 2021 BackgroundThe replication-competent human immunodeficiency virus (HIV) reservoir is the major barrier to cure. The quantitative viral outgrowth assay (QVOA), the gold-standard method to quantify replication-competent HIV, is resource intensive, wh ... Full text Cite

G-Formula for Observational Studies under Stratified Interference, with Application to Bed Net Use on Malaria

Journal Article · February 1, 2021 Assessing population-level effects of vaccines and other infectious disease prevention measures is important to the field of public health. In infectious disease studies, one person's treatment may affect another individual's outcome, i.e., there may be in ... Link to item Cite

Long-term Complications of Ebola Virus Disease: Prevalence and Predictors of Major Symptoms and the Role of Inflammation.

Journal Article Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · October 2020 BackgroundCohort studies have reported a high prevalence of musculoskeletal, neurologic, auditory, and visual complications among Ebola virus disease (EVD) survivors. However, little is known about the host- and disease-related predictors of these ... Full text Cite

Estimands and inference in cluster-randomized vaccine trials.

Journal Article Pharmaceutical statistics · September 2020 Cluster-randomized trials are often conducted to assess vaccine effects. Defining estimands of interest before conducting a trial is integral to the alignment between a study's objectives and the data to be collected and analyzed. This paper considers esti ... Full text Cite

Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme.

Journal Article Reproductive toxicology (Elmsford, N.Y.) · June 2018 In utero exposure to vinclozolin (VIN), an antiandrogenic fungicide, is linked to multigenerational phenotypic and epigenetic effects. Mechanisms remain unclear. We assessed the role of antiandrogenic activity and DNA sequence context by comparing effects ... Full text Cite