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Kara Wegermann

Assistant Professor of Medicine
Medicine, Gastroenterology

Overview


My research focuses on genetic predictors of progression in non-alcoholic fatty liver disease (NAFLD) and hepatocellular carcinoma (HCC). I have investigated predictors of clinical progression in non-alcoholic fatty liver disease using the Duke NAFLD clinical database and biorepository. I find the genetic and modifiable risk factors for liver disease fascinating, particularly because of the potential for clinical intervention before cirrhosis or HCC are established.

Current Appointments & Affiliations


Assistant Professor of Medicine · 2024 - Present Medicine, Gastroenterology, Medicine

Recent Publications


The Basics of Metabolic Dysfunction-Associated Steatotic Liver Disease for Cardiologists: Pathophysiology, Diagnosis, and Treatment.

Journal Article J Am Coll Cardiol · November 18, 2025 Metabolic dysfunction-associated steatotic liver disease (MASLD) is now recognized as a multisystem disease closely linked to cardiovascular disease, which is the leading cause of death in this population. MASLD and cardiovascular disease share overlapping ... Full text Link to item Cite

Female Sex is Protective Against MASLD With Clinically Significant Fibrosis in a Large Cross-sectional Cohort of Persons With HIV.

Journal Article Open Forum Infect Dis · November 2025 BACKGROUND: Men are at higher risk for metabolic dysfunction-associated steatotic liver disease (MASLD) with clinically significant fibrosis (CSF) than premenopausal women, but data are lacking in persons with HIV (PWH). The aim of this study was to discov ... Full text Link to item Cite
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Recent Grants


Therapeutic modulation of a proteomic HCC risk signature with statins in patients with liver cirrhosis

ResearchCo Investigator · Awarded by University of Texas - Southwestern · 2023 - 2027

The Southeastern Liver Health Cohort Study

ResearchCo Investigator · Awarded by North Carolina State University · 2023 - 2027

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Education, Training & Certifications


Harvard Medical School · 2014 M.D.