Kelly S Acharya
Assistant Professor of Obstetrics and Gynecology
Current Research Interests
Optimizing success rates in IVF, the impact of environmental factors on fertility, fertility options concurrent with a cancer diagnosis, and the evaluation of fertility in the setting of benign conditions such as endometriosis and sickle cell anemia.
Current Appointments & Affiliations
- Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Endocrinology & Fertility, Obstetrics and Gynecology 2021
Contact Information
- 5601 Arringdon Park Dr, Suite 110, Morrisville, NC 27560
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kelly.acharya@duke.edu
(919) 572-4673
- Background
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Education, Training, & Certifications
- Fellowship in Reproductive Endocrinology and Infertility, Obstetrics And Gynecology, Duke University School of Medicine 2016 - 2019
- Residency in Obstetrics and Gynecology, Obstetrics And Gynecology, Duke University School of Medicine 2012 - 2016
- M.D., University of North Carolina, Chapel Hill, School of Medicine 2012
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Previous Appointments & Affiliations
- Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Endocrinology & Fertility, Obstetrics and Gynecology 2019 - 2020
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Leadership & Clinical Positions at Duke
- Director, Duke Fertility Preservation Program
- Research
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Selected Grants
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Fellowships, Supported Research, & Other Grants
- Clinical Research / Reproductive Scientist Training Program (CREST) awarded by ASRM/NICHD/Duke 2021 - 2023
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Acharya, Kelly S., Benjamin S. Harris, Jeremy M. Weber, Tracy Truong, Carl Pieper, and Jennifer L. Eaton. “Impact of increasing antimüllerian hormone level on in vitro fertilization fresh transfer and live birth rate.” F S Rep 3, no. 3 (September 2022): 223–30. https://doi.org/10.1016/j.xfre.2022.06.005.Full Text Link to Item
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Agrawala, Shilpi, and Kelly Acharya. “Sibling rivalry? Higher birthweight after frozen embryo transfer compared with fresh sibling embryo transfers.” Fertil Steril 118, no. 2 (August 2022): 335–36. https://doi.org/10.1016/j.fertnstert.2022.05.036.Full Text Link to Item
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Chung, Esther H., Chaitanya R. Acharya, Benjamin S. Harris, and Kelly S. Acharya. “Development of a fertility risk calculator to predict individualized chance of ovarian failure after chemotherapy.” J Assist Reprod Genet 38, no. 11 (November 2021): 3047–55. https://doi.org/10.1007/s10815-021-02311-0.Full Text Link to Item
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Dorfman, Caroline S., Juliann M. Stalls, Coleman Mills, Shannon Voelkel, Mallori Thompson, Kelly S. Acharya, Karen C. Baker, et al. “Addressing Barriers to Fertility Preservation for Cancer Patients: The Role of Oncofertility Patient Navigation.” J Oncol Navig Surviv 12, no. 10 (October 2021): 332–48.Link to Item
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Chung, Esther H., Stephanie L. Lim, Evan Myers, Haley A. Moss, and Kelly S. Acharya. “Oocyte cryopreservation versus ovarian tissue cryopreservation for adult female oncofertility patients: a cost-effectiveness study.” J Assist Reprod Genet 38, no. 9 (September 2021): 2435–43. https://doi.org/10.1007/s10815-021-02222-0.Full Text Link to Item
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Woodruff, Teresa K., Lauren Ataman-Millhouse, Kelly S. Acharya, Teresa Almeida-Santos, Antoinette Anazodo, Richard A. Anderson, Leslie Appiah, et al. “A View from the past into our collective future: the oncofertility consortium vision statement.” J Assist Reprod Genet 38, no. 1 (January 2021): 3–15. https://doi.org/10.1007/s10815-020-01983-4.Full Text Link to Item
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Acharya, K. S., R. Schrott, C. Grenier, Z. Huang, Z. Holloway, A. Hawkey, E. D. Levin, and S. K. Murphy. “Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC).” Scientific Reports 10, no. 1 (December 1, 2020). https://doi.org/10.1038/s41598-020-69204-7.Full Text
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Smeltzer, S., K. Acharya, T. Truong, C. Pieper, and S. Muasher. “Single blastocyst transfer yields similar pregnancy rates compared with multiple cleavage embryo transfer, with reduced twin rate, in patients with low number of fertilized oocytes.” Middle East Fertility Society Journal 25, no. 1 (December 1, 2020). https://doi.org/10.1186/s43043-020-0016-8.Full Text
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Schrott, Rose, Maya Rajavel, Kelly Acharya, Zhiqing Huang, Chaitanya Acharya, Andrew Hawkey, Erica Pippen, H Kim Lyerly, Edward D. Levin, and Susan K. Murphy. “Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin.” Sci Rep 10, no. 1 (September 29, 2020): 16022. https://doi.org/10.1038/s41598-020-72783-0.Full Text Link to Item
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Acharya, Kelly S., Rose Schrott, Carole Grenier, Zhiqing Huang, Zade Holloway, Andrew Hawkey, Edward D. Levin, and Susan K. Murphy. “Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC).” Sci Rep 10, no. 1 (July 23, 2020): 12251. https://doi.org/10.1038/s41598-020-69204-7.Full Text Open Access Copy Link to Item
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Howell, Elizabeth P., Benjamin S. Harris, Jeffrey A. Kuller, and Kelly S. Acharya. “Preconception Evaluation Before In Vitro Fertilization.” Obstet Gynecol Surv 75, no. 6 (June 2020): 359–68. https://doi.org/10.1097/OGX.0000000000000788.Full Text Link to Item
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Schrott, Rose, Kelly Acharya, Nilda Itchon-Ramos, Andrew B. Hawkey, Erica Pippen, John T. Mitchell, Scott H. Kollins, Edward D. Levin, and Susan K. Murphy. “Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm.” Epigenetics 15, no. 1–2 (2020): 161–73. https://doi.org/10.1080/15592294.2019.1656158.Full Text Link to Item
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Jones, C. A., K. S. Acharya, C. R. Acharya, D. Raburn, and S. J. Muasher. “Patient and in vitro fertilization (IVF) cycle characteristics associated with variable blastulation rates: a retrospective study from the Duke Fertility Center (2013–2017).” Middle East Fertility Society Journal 24, no. 1 (December 1, 2019). https://doi.org/10.1186/s43043-019-0004-z.Full Text
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Smeltzer, Stephanie, Kelly Acharya, Tracy Truong, Carl Pieper, and Suheil Muasher. “Clinical pregnancy and live birth increase significantly with every additional blastocyst up to five and decline after that: an analysis of 16,666 first fresh single-blastocyst transfers from the Society for Assisted Reproductive Technology registry.” Fertil Steril 112, no. 5 (November 2019): 866-873.e1. https://doi.org/10.1016/j.fertnstert.2019.06.030.Full Text Link to Item
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Smeltzer, Stephanie, Kelly Acharya, Tracy Truong, Carl Pieper, and Suheil Muasher. “Clinical pregnancy (CP) and live birth (LB) increase significantly with each additional fertilized oocyte up to nine, and CP and LB decline after that: an analysis of 15,803 first fresh in vitro fertilization cycles from the Society for Assisted Reproductive Technology registry.” Fertil Steril 112, no. 3 (September 2019): 520-526.e1. https://doi.org/10.1016/j.fertnstert.2019.04.023.Full Text Link to Item
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Bishop, K. C., K. S. Acharya, B. S. Harris, C. R. Acharya, D. Raburn, and S. J. Muasher. “Does a freeze-all policy lead to better IVF outcomes in first autologous cycles?” Middle East Fertility Society Journal 23, no. 4 (December 1, 2018): 263–67. https://doi.org/10.1016/j.mefs.2018.07.002.Full Text
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Acharya, Kelly S., Chaitanya R. Acharya, Katherine Bishop, Benjamin Harris, Douglas Raburn, and Suheil J. Muasher. “Freezing of all embryos in in vitro fertilization is beneficial in high responders, but not intermediate and low responders: an analysis of 82,935 cycles from the Society for Assisted Reproductive Technology registry.” Fertil Steril 110, no. 5 (October 2018): 880–87. https://doi.org/10.1016/j.fertnstert.2018.05.024.Full Text Link to Item
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Acharya, Kelly, and Suheil Muasher. “Infertility patients in general and those with celiac disease may be able to breathe a sigh of relief.” Fertil Steril 110, no. 3 (August 2018): 405. https://doi.org/10.1016/j.fertnstert.2018.04.018.Full Text Link to Item
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Murphy, Susan K., Nilda Itchon-Ramos, Zachary Visco, Zhiqing Huang, Carole Grenier, Rose Schrott, Kelly Acharya, et al. “Cannabinoid exposure and altered DNA methylation in rat and human sperm.” Epigenetics 13, no. 12 (2018): 1208–21. https://doi.org/10.1080/15592294.2018.1554521.Full Text Open Access Copy Link to Item
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Acharya, Kelly S., Sanaz Keyhan, Chaitanya R. Acharya, Jason S. Yeh, Meredith P. Provost, James M. Goldfarb, and Suheil J. Muasher. “Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry.” Fertil Steril 106, no. 3 (September 1, 2016): 603–7. https://doi.org/10.1016/j.fertnstert.2016.04.039.Full Text Link to Item
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Keyhan, Sanaz, Kelly S. Acharya, Chaitanya R. Acharya, Jason S. Yeh, Meredith P. Provost, James M. Goldfarb, and Suheil J. Muasher. “How compliant are in vitro fertilization member clinics in following embryo transfer guidelines? An analysis of 59,689 fresh first in vitro fertilization autologous cycles from 2011 to 2012.” Fertil Steril 106, no. 3 (September 1, 2016): 645-652.e1. https://doi.org/10.1016/j.fertnstert.2016.05.012.Full Text Link to Item
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Provost, M. P., K. S. Acharya, C. R. Acharya, J. S. Yeh, R. G. Steward, J. L. Eaton, J. M. Goldfarb, and S. J. Muasher. “Pregnancy Outcomes Decline with Increasing Recipient Body Mass Index: An Analysis of 22,317 Fresh Donor/Recipient Cycles from the 2008-2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System Registry.” Obstetrical and Gynecological Survey 71, no. 6 (June 1, 2016): 351–52. https://doi.org/10.1097/01.ogx.0000484276.80173.0e.Full Text
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Provost, Meredith P., Kelly S. Acharya, Chaitanya R. Acharya, Jason S. Yeh, Ryan G. Steward, Jennifer L. Eaton, James M. Goldfarb, and Suheil J. Muasher. “Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008-2010 Society for Assisted Reproductive Technology registry.” Fertil Steril 105, no. 3 (March 2016): 663–69. https://doi.org/10.1016/j.fertnstert.2015.11.008.Full Text Link to Item
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Provost, Meredith P., Kelly S. Acharya, Chaitanya R. Acharya, Jason S. Yeh, Ryan G. Steward, Jennifer L. Eaton, James M. Goldfarb, and Suheil J. Muasher. “Pregnancy outcomes decline with increasing recipient body mass index: an analysis of 22,317 fresh donor/recipient cycles from the 2008-2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry.” Fertil Steril 105, no. 2 (February 2016): 364–68. https://doi.org/10.1016/j.fertnstert.2015.10.015.Full Text Link to Item
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Acharya, Kelly S., Chaitanya R. Acharya, Meredith P. Provost, Jason S. Yeh, Ryan G. Steward, Jennifer L. Eaton, and Suheil J. Muasher. “Ectopic pregnancy rate increases with the number of retrieved oocytes in autologous in vitro fertilization with non-tubal infertility but not donor/recipient cycles: an analysis of 109,140 clinical pregnancies from the Society for Assisted Reproductive Technology registry.” Fertil Steril 104, no. 4 (October 2015): 873–78. https://doi.org/10.1016/j.fertnstert.2015.06.025.Full Text Link to Item
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Acharya, K. S., M. P. Provost, J. S. Yeh, C. R. Acharya, and S. J. Muasher. “Ectopic pregnancy rates in frozen versus fresh embryo transfer in in vitro fertilization: A systematic review and meta-analysis.” Middle East Fertility Society Journal 19, no. 4 (December 1, 2014): 233–38. https://doi.org/10.1016/j.mefs.2014.09.001.Full Text
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Book Sections
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Shelby, Rebecca, Jessica Coleman, Sarah Arthur, Kelly Acharya, Amanda Heath, Margaret Flather, Kelly Westbrook, and Caroline Dorfman. “Sexual and Reproductive Health Concerns.” In Common Issues in Breast Cancer Survivors: A Practical Guide to Evaluation and Management, edited by Gretchen Kimmick, Rebecca Shelby, and Linda Sutton. Springer, 2021.Link to Item
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Acharya, Kelly, and Jennifer Eaton. “Thyroid autoimmunity and miscarriage.” In Thyroid Disease and Reproduction, edited by Jennifer Eaton. Springer, n.d.
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Conference Papers
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Harris, Benjamin S., Kelly S. Acharya, Jeremy M. Weber, Tracy Truong, and Jennifer L. Eaton. “Can high antimüllerian hormone mitigate some of the age-related decline in live birth rates? The association between antimüllerian hormone and live birth among women over 40 undergoing in vitro fertilization.” In F S Rep, 2:440–47, 2021. https://doi.org/10.1016/j.xfre.2021.08.009.Full Text Link to Item
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Shaia, Kathryn L., Kelly S. Acharya, Benjamin S. Harris, Jeremy M. Weber, Tracy Truong, and Suheil J. Muasher. “Total follicle stimulating hormone dose is negatively correlated with live births in a donor/recipient model with fresh transfer: an analysis of 8,627 cycles from the Society for Assisted Reproductive Technology Registry.” In Fertil Steril, 114:545–51, 2020. https://doi.org/10.1016/j.fertnstert.2020.04.027.Full Text Link to Item
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Datasets
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Schrott, Rose, Douglas Raburn, Scott Kollins, Edward Levin, David Corcoran, Marie-Helene Boudreau, Zhiqing Huang, et al. “Data from: Cannabinoid exposure and altered DNA methylation in rat and human sperm,” August 25, 2020. https://doi.org/10.7924/r4v122j79.Data Access
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- Teaching & Mentoring
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Recent Courses
- Scholarly, Clinical, & Service Activities
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Academic & Administrative Activities
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Director, Duke Fertility Preservation Program
Member, national research committee for the Society for Assisted Reproductive Technology (SART)
Co-Lead, Duke Oncofertility Steering Committee
REI Representative, Duke Gynecology Peer Review Committee
REI Representative, OBGYN Resident Clinical Competency Committee
REI Liaison, Duke Prematurity Prevention Program
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Director, Duke Fertility Preservation Program
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