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Christopher Ryan Kelsey

Professor of Radiation Oncology
Radiation Oncology
Radiation Oncology, Box 3085, Durham, NC 27710
30 Duke Medicine Circle, Room 05125A, Durham, NC 27710

Overview


I specialize in the treatment of hematologic and thoracic malignancies. I have a special research interest in optimizing radiation therapy in lymphomas and leukemias, particularly consolidation radiation therapy in diffuse large B-cell lymphoma and total body irradiation in the setting of allogeneic stem cell transplantation. Other academic interests include cardiac toxicity after radiation therapy for lung cancer and optimizing stereotactic body radiation therapy for stage I non-small cell lung cancer.

Current Appointments & Affiliations


Professor of Radiation Oncology · 2020 - Present Radiation Oncology, Clinical Science Departments
Member of the Duke Cancer Institute · 2017 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Impact of Myc-Altered Pathology on Radiation Therapy Efficacy Among Patients With Relapsed/Refractory Large-B Cell Lymphoma: A Collaborative Study by ILROG

Conference International Journal of Radiation Oncology Biology Physics · April 1, 2025 Purpose: The presence of MYC and BCL2 translocations (ie, double-hit lymphoma, DHL) in large B-cell lymphoma (LBCL) is associated with reduced chemosensitivity, but less is known on its impact on radiotherapy (RT) efficacy. Methods and Materials: Patients ... Full text Cite

Long-Term Toxicity after Non-Myeloablative Conditioning Regimens Using Total Body Irradiation.

Journal Article Adv Radiat Oncol · April 2025 PURPOSE: To evaluate long-term health risks after allogeneic hematopoietic stem cell transplantation (HSCT) using non-myeloablative total body irradiation (TBI). METHODS AND MATERIALS: All adult patients undergoing non-myeloablative allogeneic HSCT using T ... Full text Link to item Cite

Long-term Update of a Phase 2 Study of Dose-Reduced Radiation in Diffuse Large B-Cell Lymphoma.

Journal Article Int J Radiat Oncol Biol Phys · February 22, 2025 PURPOSE: Consolidation radiation therapy (RT) is often recommended in diffuse large B-cell lymphoma. The current recommended dose of 30 Gy was established in the pre-rituximab and PET-CT era. We hypothesized that following a complete response to modern sys ... Full text Link to item Cite
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Recent Grants


Knowledge-based Tutoring for Knowledge-based Radiation Therapy

ResearchCo Investigator · Awarded by Varian Medical Systems, Inc. · 2020 - 2022

Developing knowledge models to enable rapid learning in radiation therapy

ResearchCo Investigator · Awarded by National Institutes of Health · 2016 - 2020

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Education, Training & Certifications


University of Colorado, Denver · 2002 M.D.
Brigham Young University · 1998 B.S.