Scholars@Duke
Kimberly Breglio

Kimberly Breglio

Adjunct Assistant Professor in the Department of Dermatology
Dermatology

Selected Publications

Repair of a Lateral Large Forehead Defect.

Journal Article Dermatol Surg · May 1, 2023 Full text Link to item Cite

Quality and Perceived Usefulness of Patient-Submitted Store-and-Forward Teledermatology Images.

Journal Article JAMA Dermatol · October 1, 2022 IMPORTANCE: Patient-submitted images vary considerably in quality and usefulness. Studies that characterize patient-submitted images in a real-life setting are lacking. OBJECTIVE: To evaluate the quality and perceived usefulness of patient-submitted images ... Full text Link to item Cite

SARS-CoV-2 infections in patients with autoimmune blistering disorders: A case series and retrospective analysis.

Journal Article JAAD Int · June 2022 BACKGROUND: Autoimmune blistering disorders (AIBDs) are rare, potentially life-threatening conditions often requiring immunosuppression. Throughout the SARS-CoV-2 pandemic, infection risk and mortality in patients with AIBDs are unknown. OBJECTIVE: We repo ... Full text Link to item Cite

Clinical and Immunologic Predictors of Mycobacterium avium Complex Immune Reconstitution Inflammatory Syndrome in a Contemporary Cohort of Patients With Human Immunodeficiency Virus.

Journal Article J Infect Dis · June 15, 2021 BACKGROUND: People with human immunodeficiency virus (HIV) can present with new or worsening symptoms associated with Mycobacterium avium complex (MAC) infection shortly after antiretroviral therapy (ART) initiation as MAC immune reconstitution inflammator ... Full text Link to item Cite

Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model.

Journal Article Proc Natl Acad Sci U S A · December 4, 2018 Concerns about malaria parasite resistance to treatment with artemisinin drugs (ARTs) have grown with findings of prolonged parasite clearance t1/2s (>5 h) and their association with mutations in Plasmodium falciparum Kelch-propeller protein K13. Here, we ... Full text Link to item Cite

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.

Journal Article Malar J · October 26, 2018 BACKGROUND: Artemisinin-resistant Plasmodium falciparum has been reported throughout the Greater Mekong subregion and threatens to disrupt current malaria control efforts worldwide. Polymorphisms in kelch13 have been associated with clinical and in vitro r ... Full text Link to item Cite

Emergence of Polyfunctional Cytotoxic CD4+ T Cells in Mycobacterium avium Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Patients.

Journal Article Clin Infect Dis · July 18, 2018 BACKGROUND: Immune reconstitution inflammatory syndrome (IRIS) is an aberrant inflammatory response in individuals with advanced human immunodeficiency virus (HIV) infection, after antiretroviral therapy (ART) initiation. The pathogenesis of Mycobacterium ... Full text Link to item Cite

Kelch Mutations in Plasmodium falciparum Protein K13 Do Not Modulate Dormancy after Artemisinin Exposure and Sorbitol Selection In Vitro.

Journal Article Antimicrob Agents Chemother · May 2018 Some Kelch mutations of the Plasmodium falciparum K13 protein confer increased survival to dihydroartemisinin (DHA)-treated ring-stage parasites. Here, we asked if K13 mutations affect a dormancy phenotype allowing parasites to survive DHA exposure and the ... Full text Link to item Cite