Current Appointments & Affiliations
Assistant Professor in Neurology
·
2025 - Present
Neurology, Translational Brain Sciences,
Neurology
Assistant Professor in Pathology
·
2020 - Present
Pathology,
Clinical Science Departments
Recent Publications
Genetic associations with longevity are on average stronger in females than in males.
Journal Article Heliyon · January 15, 2024 It is long observed that females tend to live longer than males in nearly every country. However, the underlying mechanism remains elusive. In this study, we discovered that genetic associations with longevity are on average stronger in females than in mal ... Full text Link to item CiteThe APOE-TOMM40 Humanized Mouse Model: Characterization of Age, Sex, and PolyT Variant Effects on Gene Expression.
Journal Article J Alzheimers Dis · 2023 BACKGROUND: The human chromosome 19q13.32 is a gene rich region and has been associated with multiple phenotypes, including late onset Alzheimer's disease (LOAD) and other age-related conditions. OBJECTIVE: Here we developed the first humanized mouse model ... Full text Link to item CiteAlzheimer's Disease Protein Relevance Analysis Using Human and Mouse Model Proteomics Data.
Journal Article Front Syst Biol · 2023 The principles governing genotype-phenotype relationships are still emerging(1-3), and detailed translational as well as transcriptomic information is required to understand complex phenotypes, such as the pathogenesis of Alzheimer's disease. For this reas ... Full text Link to item CiteRecent Grants
Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)"
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025Gender and APOE genotype interact to alter immune regulated metabolism in AD
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2024Hematopoietic Stem Cell Transplantation Combined with CSF1 Inhibition to Attenuate the Pathogenesis of Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2023View All Grants
Education, Training & Certifications
University of Wisconsin, Madison ·
1981
Ph.D.