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Kris Mahadeo

Professor of Pediatrics
Pediatrics, Transplant and Cellular Therapy
Pediatric Transplant and Cellular Therapy, 2400 Pratt Street, Durham, NC 27705

Overview


As a committed life-long learner, I am awed by the continued advancements in the field of pediatric transplant and cellular therapy (PTCT).   Following completion of my PTCT fellowship training at Duke, I have developed a career dedicated to expanding indications for PTCT and improving associated outcomes.  I have a special interest in the mitigation of endotheliopathies and continue to lead global harmonization efforts related to management of toxicities of therapy.  As the Division Chief of PTCT at Duke, I am committed to the ensuring our patients receive state of the art care with access to innovative research protocols that change the field.   We are committed to training the next generation of physicians in our field with a commitment to global partnerships to improve care for patients across the world.

Current Appointments & Affiliations


Professor of Pediatrics · 2023 - Present Pediatrics, Transplant and Cellular Therapy, Pediatrics
Chief, Division of Pediatric Transplant & Cellular Therapy · 2023 - Present Pediatrics, Transplant and Cellular Therapy, Pediatrics
Member of the Duke Cancer Institute · 2023 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Bezlotoxumab as Treatment for Recurrent/Chronic Clostridioides difficile Infection in Pediatric Stem Cell Transplant Recipients: A Multi-Institutional Experience.

Journal Article Pediatr Blood Cancer · October 2025 Clostridioides difficile infection (CDI) represents a significant health risk to pediatric stem cell transplant (SCT) patients. In these patients, recurrent CDI is common, requiring prolonged antibiotic usage and increased hospitalization. Bezlotoxumab, a ... Full text Link to item Cite

Integrating pulmonary and systemic transcriptomes to characterize lung injury after pediatric hematopoietic stem cell transplant.

Journal Article JCI Insight · September 9, 2025 Hematopoietic stem cell transplantation (HCT) is a potentially life-saving therapy but can lead to lung injury due to chemoradiation toxicity, infection, and immune dysregulationWe previously showed that bronchoalveolar lavage (BAL) transcriptomes represen ... Full text Link to item Cite
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Education, Training & Certifications


St. George's University, School of Medicine (West Indies) · 2003 M.D.
Adelphi University · 1999 B.S.