Overview
As a committed life-long learner, I am awed by the continued advancements in the field of pediatric transplant and cellular therapy (PTCT). Following completion of my PTCT fellowship training at Duke, I have developed a career dedicated to expanding indications for PTCT and improving associated outcomes. I have a special interest in the mitigation of endotheliopathies and continue to lead global harmonization efforts related to management of toxicities of therapy. As the Division Chief of PTCT at Duke, I am committed to the ensuring our patients receive state of the art care with access to innovative research protocols that change the field. We are committed to training the next generation of physicians in our field with a commitment to global partnerships to improve care for patients across the world.
Current Appointments & Affiliations
Professor of Pediatrics
·
2023 - Present
Pediatrics, Transplant and Cellular Therapy,
Pediatrics
Chief, Division of Pediatric Transplant & Cellular Therapy
·
2023 - Present
Pediatrics, Transplant and Cellular Therapy,
Pediatrics
Member of the Duke Cancer Institute
·
2023 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Allogeneic Hematopoietic Stem Cell Transplant for an Unknown Inherited Bone Marrow Failure Syndrome With a Novel Compound Heterozygous Mutation.
Journal Article Pediatr Blood Cancer · August 2025 Full text Link to item CiteInternational expert consensus statement on PICU admission and early critical care management for paediatric patients following haematopoietic cell transplant and immune effector cell therapy.
Journal Article Lancet Child Adolesc Health · June 2025 Advances in paediatric haematopoietic cell transplantation strategies using immune-effector cells (HCT-IEC) and in intensive care management have improved survival expectations for patients with malignant and non-malignant diseases. However, critical illne ... Full text Link to item CiteNewborn Screening for Hurler Syndrome Facilitates Early Transplant and Good Outcomes.
Journal Article Pediatr Neurol · February 2025 BACKGROUND: Hematopoietic cell transplantation (HCT) is the standard of care treatment for children with Hurler syndrome (HS). This study describes the impact of newborn screening (NBS) on HCT outcomes for these patients. METHODS: Retrospective study of HS ... Full text Link to item CiteRecent Grants
A Phase 1/2, Open-Label, Basket Study of Afamitresgene Autoleucel in Pediatric Subjects with MAGE-A4 Positive Tumors
Clinical TrialPrincipal Investigator · Awarded by Adaptimmune LLC · 2024 - 2038A randomized trial of low versus moderate exposure busulfan for infants with severe combined immunodeficiency (SCID) receiving TCR¿ss+/CD19+ depleted transplantation
Clinical TrialPrincipal Investigator · Awarded by National Marrow Donor Program · 2025 - 2029Addressing Food Insecurity in Transplant and Cellular Therapy Patients with Healthcare-Community Partnerships
ResearchPrincipal Investigator · Awarded by The University of Kansas Medical Center Research Institute, Inc · 2024 - 2029View All Grants
Education, Training & Certifications
St. George's University, School of Medicine (West Indies) ·
2003
M.D.
Adelphi University ·
1999
B.S.