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Kris Mahadeo

Professor of Pediatrics
Pediatrics, Transplant and Cellular Therapy
Pediatric Transplant and Cellular Therapy, 2400 Pratt Street, Durham, NC 27705

Overview


As a committed life-long learner, I am awed by the continued advancements in the field of pediatric transplant and cellular therapy (PTCT).   Following completion of my PTCT fellowship training at Duke, I have developed a career dedicated to expanding indications for PTCT and improving associated outcomes.  I have a special interest in the mitigation of endotheliopathies and continue to lead global harmonization efforts related to management of toxicities of therapy.  As the Division Chief of PTCT at Duke, I am committed to the ensuring our patients receive state of the art care with access to innovative research protocols that change the field.   We are committed to training the next generation of physicians in our field with a commitment to global partnerships to improve care for patients across the world.

Current Appointments & Affiliations


Professor of Pediatrics · 2023 - Present Pediatrics, Transplant and Cellular Therapy, Pediatrics
Chief, Division of Pediatric Transplant & Cellular Therapy · 2023 - Present Pediatrics, Transplant and Cellular Therapy, Pediatrics
Member of the Duke Cancer Institute · 2023 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


International expert consensus statement on PICU admission and early critical care management for paediatric patients following haematopoietic cell transplant and immune effector cell therapy.

Journal Article Lancet Child Adolesc Health · June 2025 Advances in paediatric haematopoietic cell transplantation strategies using immune-effector cells (HCT-IEC) and in intensive care management have improved survival expectations for patients with malignant and non-malignant diseases. However, critical illne ... Full text Link to item Cite

Newborn Screening for Hurler Syndrome Facilitates Early Transplant and Good Outcomes.

Journal Article Pediatr Neurol · February 2025 BACKGROUND: Hematopoietic cell transplantation (HCT) is the standard of care treatment for children with Hurler syndrome (HS). This study describes the impact of newborn screening (NBS) on HCT outcomes for these patients. METHODS: Retrospective study of HS ... Full text Link to item Cite
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Recent Grants


A Phase 1/2, Open-Label, Basket Study of Afamitresgene Autoleucel in Pediatric Subjects with MAGE-A4 Positive Tumors

Clinical TrialPrincipal Investigator · Awarded by Adaptimmune LLC · 2024 - 2038

Addressing Food Insecurity in Transplant and Cellular Therapy Patients with Healthcare-Community Partnerships

ResearchPrincipal Investigator · Awarded by The University of Kansas Medical Center Research Institute, Inc · 2024 - 2029

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Education, Training & Certifications


St. George's University, School of Medicine (West Indies) · 2003 M.D.
Adelphi University · 1999 B.S.