Scholars@Duke
Kristin Corey
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Selected Publications

Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study.

Journal Article Anesthesiology · July 1, 2022 BACKGROUND: COVID-19 causes hypercoagulability, but the association between coagulopathy and hypoxemia in critically ill patients has not been thoroughly explored. This study hypothesized that severity of coagulopathy would be associated with acute respira ... Full text Link to item Cite

Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The "PRONE" Study.

Journal Article Contemp Clin Trials · October 2021 While benefits of prone position in mechanically-ventilated patients have been well-described, a randomized-control trial to determine the effects of prone positioning in awake, spontaneously-breathing patients with an acute pneumonia has not been previous ... Full text Link to item Cite

COVID-19: Thrombosis, thromboinflammation, and anticoagulation considerations.

Journal Article Int J Lab Hematol · July 2021 Vascular endothelial injury is a hallmark of acute infection at both the microvascular and macrovascular levels. The hallmark of SARS-CoV-2 infection is the current COVID-19 clinical sequelae of the pathophysiologic responses of hypercoagulability and thro ... Full text Open Access Link to item Cite

Wide range of perioperative drugs and doses used in inguinal hernia repairs for premature infants.

Journal Article J Perinatol · March 2021 OBJECTIVE: Characterize the types and doses of commonly administered perioperative drugs in inguinal hernia (IH) repair for premature infants. STUDY DESIGN: Single-center, retrospective cohort study. RESULTS: In total, 112 premature infants underwent IH re ... Full text Link to item Cite

Machine Learning for Predictive Analytics

Book · November 20, 2020 Provides an overview of machine learning, both for a clinical and engineering audience Summarize recent advances in both cardiovascular medicine and artificial intelligence Discusses the advantages of using machine learning for outcomes ... ... Cite

Real-World Integration of a Sepsis Deep Learning Technology Into Routine Clinical Care: Implementation Study.

Journal Article JMIR Med Inform · July 15, 2020 BACKGROUND: Successful integrations of machine learning into routine clinical care are exceedingly rare, and barriers to its adoption are poorly characterized in the literature. OBJECTIVE: This study aims to report a quality improvement effort to integrate ... Full text Link to item Cite

Machine learning for early detection of sepsis: an internal and temporal validation study.

Journal Article JAMIA Open · July 2020 OBJECTIVE: Determine if deep learning detects sepsis earlier and more accurately than other models. To evaluate model performance using implementation-oriented metrics that simulate clinical practice. MATERIALS AND METHODS: We trained internally and tempor ... Full text Open Access Link to item Cite

Assessing Quality of Surgical Real-World Data from an Automated Electronic Health Record Pipeline.

Journal Article J Am Coll Surg · March 2020 BACKGROUND: Significant analysis errors can be caused by nonvalidated data quality of electronic health records data. To determine surgical data fitness, a framework of foundational and study-specific data analyses was adapted and assessed using conformanc ... Full text Link to item Cite

Pulmonary Valve Endocarditis: The Potential Utility of Multimodal Imaging Prior to Surgery.

Journal Article World J Pediatr Congenit Heart Surg · March 2020 BACKGROUND: The presence of echocardiographic (echo) evidence is a major criterion for the diagnosis of infective endocarditis (IE) by modified Duke criteria. Pulmonary valve (PV) IE, however, can be challenging to identify by echo. We sought to evaluate t ... Full text Link to item Cite

Development and validation of machine learning models to identify high-risk surgical patients using automatically curated electronic health record data (Pythia): A retrospective, single-site study.

Journal Article PLoS Med · November 2018 BACKGROUND: Pythia is an automated, clinically curated surgical data pipeline and repository housing all surgical patient electronic health record (EHR) data from a large, quaternary, multisite health institute for data science initiatives. In an effort to ... Full text Link to item Cite

Clinical outcomes in very low birth weight infants with major congenital heart defects.

Journal Article Early Hum Dev · December 2014 BACKGROUND: The combination of major congenital heart disease (CHD) and prematurity is associated with poor prognosis, but previous studies have not fully characterized morbidity and mortality in this population. We conducted a retrospective cohort study o ... Full text Link to item Cite

Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele.

Journal Article Early Hum Dev · August 2014 BACKGROUND: Gastroschisis and omphalocele are the most common anterior abdominal wall defects affecting infants. There are few large cohort studies describing the frequency of associated anomalies in infants with these 2 conditions. We describe associated ... Full text Link to item Cite

Safety of cardiac devices in children

Journal Article Progress in Pediatric Cardiology · May 1, 2012 Implanted cardiac devices have improved and prolonged the lives of countless children. Some of these devices have undergone vigorous pre-market assessment and are US Food and Drug Administration (FDA) approved for use in children; however, many devices are ... Full text Cite

An Evaluation of College Online Alcohol-Policy Information: 2007 Compared With 2002

Journal Article Journal of Studies on Alcohol and Drugs, Supplement · July 2009 Full text Cite