Scholars@Duke
Kristin E.D. Weimer

Kristin E.D. Weimer

Assistant Professor of Pediatrics
Pediatrics, Neonatology
kristin.weimer@duke.edu
DUMC 102509, Durham, NC 27710
2400 Pratt Street, 8th Floor, Durham, NC 27705
Manage Profile
Embed Profile Data

Selected Publications

Improved Dried Blood Spot PCR Assay for Universal Congenital Cytomegalovirus Screening in Newborns.

Journal Article Microbiol Spectr · March 20, 2023 Congenital cytomegalovirus (cCMV) is the most common perinatal infection, the leading cause of nongenetic sensorineural hearing loss, and one of the leading causes of neurodevelopmental impairment in the developed world. Early identification via newborn sc ... Full text Link to item Cite

Breast Milk and Saliva for Postnatal Cyto†megalovirus Screening among Very Low Birth Weight Infants.

Journal Article Pediatr Infect Dis J · November 1, 2022 BACKGROUND: The optimal approach to managing postnatal cytomegalovirus disease (pCMV) among very low birth weight (VLBW) infants remains unknown. Methods to facilitate screening are needed. OBJECTIVE: Determine whether mother's milk and infant saliva can b ... Full text Link to item Cite

Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series.

Journal Article Pediatr Infect Dis J · April 1, 2022 BACKGROUND: There has been a 291% relative increase in congenital syphilis (CS) cases in the United States from 2015 to 2019. Although the majority of affected fetuses/infants are stillborn or are asymptomatic, a subset is born with severe clinical illness ... Full text Link to item Cite

Invasive fungal infections in neonates: a review.

Journal Article Pediatr Res · January 2022 Invasive fungal infections remain the leading causes of morbidity and mortality in neonates, especially preterm and very low birth weight infants. Most invasive fungal infections are due to Candida or Aspergillus species, and other fungi are increasingly r ... Full text Link to item Cite

Comparison of short-term outcomes of 35-weeks' gestation infants cared for in a level II NICU vs mother-baby, a retrospective study.

Journal Article J Neonatal Perinatal Med · 2022 BACKGROUND: Late preterm infants are at high risk for medical complications and represent a growing NICU population. While 34-weeks' gestation infants are generally admitted to the NICU and 36-weeks'gestation infants stay in mother-baby, there is wide prac ... Full text Link to item Cite

Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection.

Journal Article Am J Perinatol · August 2021 OBJECTIVE: Very low birth weight preterm infants are at risk for life-threatening infections in the NICU. Breast milk protects against infections but carries the risk of infection by cytomegalovirus (CMV) shed in mother's milk. Lactoferrin is a breast milk ... Full text Link to item Cite

Long-term Outcomes after Postnatal Cytomegalovirus Infection in Low Birthweight Preterm Infants: A Systematic Review.

Journal Article Pediatr Infect Dis J · June 1, 2021 BACKGROUND: Cytomegalovirus (CMV) is the most common viral infection seen in newborns. Although postnatally acquired CMV (pCMV) infection rarely results in serious manifestations in term infants, preterm infants can develop severe clinical illness. However ... Full text Link to item Cite

Postnatally acquired CMV meningitis diagnosed via BioFire FilmArray: A case report.

Journal Article J Neonatal Perinatal Med · 2021 Postnatally acquired cytomegalovirus (CMV) is commonly acquired via breast milk, with premature infants more frequently developing symptoms of CMV infection in comparison to term infants. Meningitis is a rare clinical manifestation of CMV infection. The di ... Full text Link to item Cite

Economic Evaluation of Catheter Ablation of Atrial Fibrillation in Patients with Heart Failure With Reduced Ejection Fraction.

Journal Article Circ Cardiovasc Qual Outcomes · December 2020 BACKGROUND: Randomized clinical trials have demonstrated that catheter ablation for atrial fibrillation in patients with heart failure with reduced ejection fraction may improve survival and other cardiovascular outcomes. METHODS: We constructed a decision ... Full text Link to item Cite

Association of Adverse Hearing, Growth, and Discharge Age Outcomes With Postnatal Cytomegalovirus Infection in Infants With Very Low Birth Weight.

Journal Article JAMA Pediatr · February 1, 2020 IMPORTANCE: Studies suggest that postnatal cytomegalovirus (CMV) infection can lead to long-term morbidity in infants with very low birth weight (VLBW; <1500 g), including bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), and neurodevelopm ... Full text Link to item Cite

When and How to Treat Neonatal CMV Infection

Chapter · January 1, 2018 Cytomegalovirus (CMV) is the most common perinatal infection worldwide and the leading infectious cause of hearing loss and neurologic deficits, affecting up to 1% of live births worldwide. CMV can be acquired by infants either in utero (congenital infecti ... Full text Cite

Direct Evaluation of Pseudomonas aeruginosa Biofilm Mediators in a Chronic Infection Model

Journal Article Infection and Immunity · August 2011 ABSTRACT Biofilms contribute to Pseudomonas aeruginosa ... Full text Cite

Nontypeable Haemophilus influenzae Initiates Formation of Neutrophil Extracellular Traps

Journal Article Infection and Immunity · January 2011 ABSTRACT Nontypeable Haemophilus influenzae (NTHI) is a leading cause of otitis media infections, which are often chronic and/or recurrent in nature. ... Full text Cite

Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling

Journal Article mBio · August 31, 2010 ABSTRACT Otitis media (OM) is among the leading diseases of childhood and is caused by opportunists that reside within the nasopharynx, such as Haemophilus influenzae Full text Cite

LuxS Promotes Biofilm Maturation and Persistence of Nontypeable Haemophilus influenzae In Vivo via Modulation of Lipooligosaccharides on the Bacterial Surface

Journal Article Infection and Immunity · September 2009 ABSTRACT Nontypeable Haemophilus influenzae (NTHI) is an extremely common airway commensal which can cause opportunistic infections that are usually ... Full text Cite

Improved Dried Blood Spot PCR Assay for Universal Congenital Cytomegalovirus Screening in Newborns.

Journal Article Microbiol Spectr · March 20, 2023 Congenital cytomegalovirus (cCMV) is the most common perinatal infection, the leading cause of nongenetic sensorineural hearing loss, and one of the leading causes of neurodevelopmental impairment in the developed world. Early identification via newborn sc ... Full text Link to item Cite

Breast Milk and Saliva for Postnatal Cyto†megalovirus Screening among Very Low Birth Weight Infants.

Journal Article Pediatr Infect Dis J · November 1, 2022 BACKGROUND: The optimal approach to managing postnatal cytomegalovirus disease (pCMV) among very low birth weight (VLBW) infants remains unknown. Methods to facilitate screening are needed. OBJECTIVE: Determine whether mother's milk and infant saliva can b ... Full text Link to item Cite

Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series.

Journal Article Pediatr Infect Dis J · April 1, 2022 BACKGROUND: There has been a 291% relative increase in congenital syphilis (CS) cases in the United States from 2015 to 2019. Although the majority of affected fetuses/infants are stillborn or are asymptomatic, a subset is born with severe clinical illness ... Full text Link to item Cite

Invasive fungal infections in neonates: a review.

Journal Article Pediatr Res · January 2022 Invasive fungal infections remain the leading causes of morbidity and mortality in neonates, especially preterm and very low birth weight infants. Most invasive fungal infections are due to Candida or Aspergillus species, and other fungi are increasingly r ... Full text Link to item Cite

Comparison of short-term outcomes of 35-weeks' gestation infants cared for in a level II NICU vs mother-baby, a retrospective study.

Journal Article J Neonatal Perinatal Med · 2022 BACKGROUND: Late preterm infants are at high risk for medical complications and represent a growing NICU population. While 34-weeks' gestation infants are generally admitted to the NICU and 36-weeks'gestation infants stay in mother-baby, there is wide prac ... Full text Link to item Cite

Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection.

Journal Article Am J Perinatol · August 2021 OBJECTIVE: Very low birth weight preterm infants are at risk for life-threatening infections in the NICU. Breast milk protects against infections but carries the risk of infection by cytomegalovirus (CMV) shed in mother's milk. Lactoferrin is a breast milk ... Full text Link to item Cite

Long-term Outcomes after Postnatal Cytomegalovirus Infection in Low Birthweight Preterm Infants: A Systematic Review.

Journal Article Pediatr Infect Dis J · June 1, 2021 BACKGROUND: Cytomegalovirus (CMV) is the most common viral infection seen in newborns. Although postnatally acquired CMV (pCMV) infection rarely results in serious manifestations in term infants, preterm infants can develop severe clinical illness. However ... Full text Link to item Cite

Postnatally acquired CMV meningitis diagnosed via BioFire FilmArray: A case report.

Journal Article J Neonatal Perinatal Med · 2021 Postnatally acquired cytomegalovirus (CMV) is commonly acquired via breast milk, with premature infants more frequently developing symptoms of CMV infection in comparison to term infants. Meningitis is a rare clinical manifestation of CMV infection. The di ... Full text Link to item Cite

Economic Evaluation of Catheter Ablation of Atrial Fibrillation in Patients with Heart Failure With Reduced Ejection Fraction.

Journal Article Circ Cardiovasc Qual Outcomes · December 2020 BACKGROUND: Randomized clinical trials have demonstrated that catheter ablation for atrial fibrillation in patients with heart failure with reduced ejection fraction may improve survival and other cardiovascular outcomes. METHODS: We constructed a decision ... Full text Link to item Cite

Association of Adverse Hearing, Growth, and Discharge Age Outcomes With Postnatal Cytomegalovirus Infection in Infants With Very Low Birth Weight.

Journal Article JAMA Pediatr · February 1, 2020 IMPORTANCE: Studies suggest that postnatal cytomegalovirus (CMV) infection can lead to long-term morbidity in infants with very low birth weight (VLBW; <1500 g), including bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), and neurodevelopm ... Full text Link to item Cite

When and How to Treat Neonatal CMV Infection

Chapter · January 1, 2018 Cytomegalovirus (CMV) is the most common perinatal infection worldwide and the leading infectious cause of hearing loss and neurologic deficits, affecting up to 1% of live births worldwide. CMV can be acquired by infants either in utero (congenital infecti ... Full text Cite

Direct Evaluation of Pseudomonas aeruginosa Biofilm Mediators in a Chronic Infection Model

Journal Article Infection and Immunity · August 2011 ABSTRACT Biofilms contribute to Pseudomonas aeruginosa ... Full text Cite

Nontypeable Haemophilus influenzae Initiates Formation of Neutrophil Extracellular Traps

Journal Article Infection and Immunity · January 2011 ABSTRACT Nontypeable Haemophilus influenzae (NTHI) is a leading cause of otitis media infections, which are often chronic and/or recurrent in nature. ... Full text Cite

Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling

Journal Article mBio · August 31, 2010 ABSTRACT Otitis media (OM) is among the leading diseases of childhood and is caused by opportunists that reside within the nasopharynx, such as Haemophilus influenzae Full text Cite

LuxS Promotes Biofilm Maturation and Persistence of Nontypeable Haemophilus influenzae In Vivo via Modulation of Lipooligosaccharides on the Bacterial Surface

Journal Article Infection and Immunity · September 2009 ABSTRACT Nontypeable Haemophilus influenzae (NTHI) is an extremely common airway commensal which can cause opportunistic infections that are usually ... Full text Cite