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Alexander Kulminski

Research Professor in the Social Science Research Institute
Social Science Research Institute
Box 90420, Durham, NC 27708-0408
2024 W. Main St., Box 90420, Durham, NC 27708-0420

Current Appointments & Affiliations


Research Professor in the Social Science Research Institute · 2021 - Present Social Science Research Institute, University Institutes and Centers

In the News


Published September 24, 2019
Alzheimer's Has Many Causes. Research Needs to Be Broader

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Recent Publications


Association of APOE alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease neuroimaging markers.

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · February 2025 IntroductionTOMM40 and APOC1 variants can modulate the APOE-ε4-related Alzheimer's disease (AD) risk by up to fourfold. We aim to investigate whether the genetic modulation of ε4-related AD risk is reflected in brain morphology.MethodsWe ... Full text Cite

Complex genetic interactions affect susceptibility to Alzheimer's disease risk in the BIN1 and MS4A6A loci

Journal Article Geroscience · January 1, 2025 Genetics is the second strongest risk factor for Alzheimer’s disease (AD) after age. More than 70 loci have been implicated in AD susceptibility so far, and the genetic architecture of AD entails both additive and nonadditive contributions from these loci. ... Full text Cite

Basic Science and Pathogenesis

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 1, 2024 BACKGROUND: The Alzheimer's Association reports that more than two-thirds of the approximately 5 million Alzheimer's disease (AD) cases in the USA are women. With studies suggesting a high genetic heritability for AD, gaining a better understanding of the ... Full text Cite
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Recent Grants


Dissecting genetic and non-genetic heterogeneity in predisposition to Alzheimer's disease and vascular traits in pleiotropic context

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2026

Project 1: The Long Life Family Study

ResearchSenior Research Scientist · Awarded by Washington University in St. Louis · 2019 - 2026

Personalized genetic profiles of risk and resilience in Alzheimer's and vascular diseases

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2020 - 2026

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Education, Training & Certifications


The National Academy of Sciences of Belarus (Republic of Belarus) · 1991 Ph.D.