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Alexander Kulminski

Research Professor in the Social Science Research Institute
Social Science Research Institute
Box 90420, Durham, NC 27708-0408
2024 W. Main St., Box 90420, Durham, NC 27708-0420

Current Appointments & Affiliations


Research Professor in the Social Science Research Institute · 2021 - Present Social Science Research Institute, University Institutes and Centers

In the News


Published September 24, 2019
Alzheimer's Has Many Causes. Research Needs to Be Broader

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Recent Publications


Complex genetic interactions affect susceptibility to Alzheimer's disease risk in the BIN1 and MS4A6A loci

Journal Article GeroScience · January 1, 2025 Genetics is the second strongest risk factor for Alzheimer’s disease (AD) after age. More than 70 loci have been implicated in AD susceptibility so far, and the genetic architecture of AD entails both additive and nonadditive contributions from these loci. ... Full text Cite

Basic Science and Pathogenesis

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 1, 2024 BACKGROUND: The Alzheimer's Association reports that more than two-thirds of the approximately 5 million Alzheimer's disease (AD) cases in the USA are women. With studies suggesting a high genetic heritability for AD, gaining a better understanding of the ... Full text Cite

Pleiotropic Associations with Alzheimer's Disease and Physical Activity: Sex Differences and the Effects of Environment.

Journal Article International journal of molecular sciences · November 2024 Physical activity (PA) is a modifiable factor in mitigating/preventing Alzheimer's disease (AD). It is crucial to identify the conditions under which PA's effects on AD risk would be beneficial. This study aims to gain insights into pleiotropic predisposit ... Full text Cite
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Recent Grants


Dissecting genetic and non-genetic heterogeneity in predisposition to Alzheimer's disease and vascular traits in pleiotropic context

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2026

Personalized genetic profiles of risk and resilience in Alzheimer's and vascular diseases

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2020 - 2026

ApoE2 and protective molecular signatures in Alzheimer's disease and aging

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2025

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Education, Training & Certifications


The National Academy of Sciences of Belarus (Republic of Belarus) · 1991 Ph.D.