Madan Mohan Kwatra
Associate Professor in Anesthesiology

The focus of this laboratory is on signaling through G protein-coupled receptors and clinical proteomics. These goals are currently being realized through three major projects: (1) Mechanism of signal transduction through substance P receptor in human glioblastomas; (2) Effect of age and diabetes on G protein-coupled receptors in human heart; and (3) Molecular basis of postoperative delirium in the elderly. Our studies use state-of-the-art techniques in protein biochemistry and molecular biology including DNA microarrays. A major goal of project #3 is to identify biomarkers of delirium in plasma using a proteomic approach including analyses by 2D-gel electrophoresis, mass spectrometry,SELDI/TOF (protein-chip), and protein microarrays.

Current Appointments & Affiliations

Contact Information

  • 146 Sands Bldg, Durham, NC 27710
  • Box 3094 Med Ctr, Durham, NC 27710

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