Overview
I work with Dr. Catherine Bowes Rickman in the Department of Ophthalmology, where we are developing therapies to prevent blindness in age-related macular degeneration.
Recent Publications
The insulin-like peptides Dilp2 and Dilp6 exhibit divergent responses to dietary sugar and protein in <i>Drosophila</i> larvae.
Journal Article Proceedings of the National Academy of Sciences of the United States of America · October 2025 Nutrient intake drives secretion of insulin and insulin-like peptides that stimulate anabolic metabolism and tissue growth. Eight Drosophila insulin-like peptides (Dilps) are encoded in the Drosophila genome; whether these Dilps respond unifo ... Full text CiteTruncated complement factor H Y402 gene therapy rescues C3 glomerulonephritis.
Journal Article Mol Ther · August 6, 2025 There are no effective therapies for patients with dry age-related macular degeneration (AMD) or C3 glomerulonephritis (C3G). Unfortunately, past efforts to treat C3G using exogenous human complement factor H (CFH) found limited success due to immune rejec ... Full text Link to item CiteSynchronizing Drosophila larvae with the salivary gland reporter Sgs3-GFP for discovery of phenotypes in the late third instar stage.
Journal Article Developmental Biology · August 2024 Full text CiteRecent Grants
Gene therapy targeting CFH and lipoprotein dynamics in AMD
ResearchGraduate Student · Awarded by National Institutes of Health · 2025 - 2028View All Grants