Scholars@Duke
Lauren Beth Cooper

Lauren Beth Cooper

Adjunct Associate in the Department of Medicine
Medicine, Cardiology

Selected Publications

Amiodarone use in patients listed for heart transplant is associated with increased 1-year post-transplant mortality.

Journal Article J Heart Lung Transplant · February 2017 BACKGROUND: Pre-transplant amiodarone use has been postulated as a risk factor for morbidity and mortality after orthotopic heart transplantation (OHT). We assessed pre-OHT amiodarone use and tested the hypothesis that it is associated with impaired post-O ... Full text Link to item Cite

Clinical Implications of Serum Albumin Levels in Acute Heart Failure: Insights From DOSE-AHF and ROSE-AHF.

Journal Article J Card Fail · November 2016 BACKGROUND: Hypoalbuminemia is common in patients with chronic heart failure and, as a marker of disease severity, is associated with an adverse prognosis. Whether hypoalbuminemia contributes to (or is associated with) worse outcomes in acute heart failure ... Full text Link to item Cite

Serum Bicarbonate in Acute Heart Failure: Relationship to Treatment Strategies and Clinical Outcomes.

Journal Article J Card Fail · September 2016 BACKGROUND: Though commonly noted in clinical practice, it is unknown if decongestion in acute heart failure (AHF) results in increased serum bicarbonate. METHODS AND RESULTS: For 678 AHF patients in the DOSE-AHF, CARRESS-HF, and ROSE-AHF trials, we assess ... Full text Link to item Cite

Use of Heart Failure Medical Therapies Among Patients With Left Ventricular Assist Devices: Insights From INTERMACS.

Journal Article J Card Fail · September 2016 BACKGROUND: Use of left ventricular assist devices (LVADs) for treatment of advanced heart failure has expanded significantly over the past decade. However, concomitant use of heart failure medical therapies after implant is poorly characterized. METHODS A ... Full text Link to item Cite

Trends and outcomes of patients with adult congenital heart disease and pulmonary hypertension listed for orthotopic heart transplantation in the United States.

Journal Article J Heart Lung Transplant · May 2016 BACKGROUND: Heart transplantation is increasing in patients with adult congenital heart disease (ACHD). In this population, the association of pulmonary hypertension (PH) with post-transplant outcomes is not well-defined. METHODS: Using data from the Unite ... Full text Link to item Cite

Cardiac transplantation for older patients: Characteristics and outcomes in the septuagenarian population.

Journal Article J Heart Lung Transplant · March 2016 BACKGROUND: With increasing age of patients with heart failure, it is important to understand the potential role for orthotopic heart transplant (OHT) in elderly patients. We examined recipient and donor characteristics and long-term outcomes of older reci ... Full text Link to item Cite

Hemodynamic Predictors of Heart Failure Morbidity and Mortality: Fluid or Flow?

Journal Article J Card Fail · March 2016 BACKGROUND: Patients with advanced heart failure may continue for prolonged times with persistent hemodynamic abnormalities; intermediate- and long-term outcomes of these patients are unknown. METHODS AND RESULTS: We used ESCAPE (Evaluation Study of Conges ... Full text Link to item Cite

Pulmonary Hypertension in the Era of Mechanical Circulatory Support.

Journal Article ASAIO J · 2016 Left heart disease (LHD) represents the most common cause of pulmonary hypertension (PH), and is associated with worse prognosis compared with LHD without PH. In addition, PH due to LHD may prevent patients from receiving heart transplantation, because of ... Full text Link to item Cite

Differences in health care use and outcomes by the timing of in-hospital worsening heart failure.

Journal Article Am Heart J · December 2015 BACKGROUND: Patients hospitalized with acute heart failure may experience worsening symptoms requiring escalation of therapy. In-hospital worsening heart failure is associated with worse in-hospital and postdischarge outcomes, but associations between the ... Full text Link to item Cite

Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION).

Journal Article Circ Heart Fail · November 2015 BACKGROUND: Psychosocial factors may influence adherence with exercise training for heart failure (HF) patients. We aimed to describe the association between social support and barriers to participation with exercise adherence and clinical outcomes. METHOD ... Full text Link to item Cite

The Impact of Worsening Heart Failure in the United States.

Journal Article Heart Fail Clin · October 2015 In-hospital worsening heart failure represents a clinical scenario wherein a patient hospitalized for acute heart failure experiences a worsening of their condition, requiring escalation of therapy. Worsening heart failure is associated with worse in-hospi ... Full text Open Access Link to item Cite

Assessing the Quality and Comparative Effectiveness of Team-Based Care for Heart Failure: Who, What, Where, When, and How.

Journal Article Heart Fail Clin · July 2015 Team-based or multidisciplinary care may be a potential way to positively impact outcomes for heart failure (HF) patients by improving clinical outcomes, managing patient symptoms, and reducing costs. The multidisciplinary team includes the HF cardiologist ... Full text Link to item Cite

Commentary

Journal Article Annals of Internal Medicine · December 16, 2014 Cite