Current Appointments & Affiliations
Associate Professor in Neurology
·
2025 - Present
Neurology, Translational Brain Sciences,
Neurology
Associate Professor of Pathology
·
2022 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Member in the Duke Clinical Research Institute
·
2021 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Basic Science and Pathogenesis
Journal Article Alzheimer S Dementia the Journal of the Alzheimer S Association · December 1, 2025 BACKGROUND: Alzheimer's disease (AD) and primary tauopathies are characterized by pathological tau aggregation, in the form of neurofibrillary tangles and dystrophic neurites. Recent evidence suggests tau pathology is also commonly observed in synucleinopa ... Full text CiteLRRK2 kinase-mediated accumulation of lysosome-associated phospho-Rabs in tauopathies and synucleinopathies.
Journal Article Acta Neuropathol · October 23, 2025 Parkinson's disease (PD) pathogenic mutations in leucine-rich repeat kinase 2 (LRRK2) are associated with endolysosomal dysfunction across cell types, and carriers of LRRK2 mutations variably present with phosphorylated tau and α-synuclein deposits in post ... Full text Link to item CiteLessons from the Tim Greenamyre model.
Journal Article Neurobiol Dis · September 2025 Full text Link to item CiteRecent Grants
PD OLE
Clinical TrialPrincipal Investigator · Awarded by Annovis Bio, Inc. · 2025 - 2030The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2029Duke University Program in Environmental Health
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Environmental Health Sciences · 2019 - 2029View All Grants
Education
University at Buffalo, Jacobs School of Medicine and Biomedical Sciences ·
2008
Ph.D.