Current Duke Appointments & Affiliations
Associate Professor in Neurology
·
2025 - Present
Neurology, Translational Brain Sciences,
Neurology
Associate Professor of Pathology
·
2022 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Member in the Duke Clinical Research Institute
·
2021 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Scholarly Works
Wearable-sensor based walking and non-walking measures as progression markers in early to mid-stage Parkinson's disease.
Journal article NPJ Parkinsons Dis · April 18, 2026 Digital measures of walking and sedentariness may objectively quantify Parkinson's disease (PD) progression. We analyzed longitudinal wearable-sensor data to evaluate the sensitivity and specificity of digital walking and non-walking measures in ambulatory ... Full text Link to item CiteHypomorphic Protein Expression of DNA Polymerase Beta in PolβL301R-V303R/L301R-V303R Knock-In Transgenic Mice Does Not Impact Global DNA Methylation Levels in the Midbrain.
Journal article Biomolecules · March 11, 2026 DNA polymerase beta (Polβ) is a 39 kDa, single polypeptide enzyme that possesses both gap tailoring and nucleotidyl transferase activity and is the key polymerase involved in base excision repair (BER) and the final steps of active gene demethylation. We d ... Full text Link to item CiteE3 ubiquitin ligases in neurodegenerative diseases.
Journal article Mil Med Res · 2026 Neurodegenerative diseases (NDs) are characterized by progressive neuronal loss and proteostatic failure, driven by impaired clearance of misfolded proteins via the ubiquitin-proteasome system (UPS) and autophagy. In UPS, E3 ubiquitin ligases are crucial f ... Full text Link to item CiteRecent Grants
PD OLE
Clinical TrialPrincipal Investigator · Awarded by Annovis Bio, Inc. · 2025 - 2030The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)
ResearchCo-Principal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029Duke University Program in Environmental Health
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Environmental Health Sciences · 2019 - 2029View All Grants
Education
University at Buffalo, Jacobs School of Medicine and Biomedical Sciences ·
2008
Ph.D.