Skip to main content

Leanna Ross

Assistant Professor in Medicine
Medicine, Cardiology
3475 Erwin Road, Aesthetics Bldg., Rm 281, Durham, NC 27705

Overview


Dr. Ross's research focuses on understanding the mechanisms by which exercise interventions elicit short- and long-term cardiometabolic health benefits.  As cardiometabolic disease remains the leading cause of morbidity and mortality in the United States, the goal of her translational research is to enhance the development of evidence-based, precision exercise interventions that optimally prevent and treat disease.

Areas of Research Interest
Exercise dose-response and cardiometabolic health
Insulin action and glucose homeostasis
Legacy health benefits of exercise
Heterogeneity of response to exercise intervention
Precision lifestyle medicine
Epidemiology of physical activity and cardiorespiratory fitness

Current Appointments & Affiliations


Assistant Professor in Medicine · 2024 - Present Medicine, Cardiology, Medicine
Member of Duke Molecular Physiology Institute · 2022 - Present Duke Molecular Physiology Institute, Institutes and Centers

In the News


Published January 8, 2024
Study of Duke Heart Attack Patients Finds Definitive Benefit of Cardiac Rehab

View All News

Recent Publications


Biomarkers of Insulin Resistance and Their Performance as Predictors of Treatment Response in Overweight Adults.

Journal Article J Clin Endocrinol Metab · December 18, 2025 CONTEXT: Insulin resistance (IR) contributes to the pathogenesis of type 2 diabetes mellitus and is a risk factor for cardiovascular and neurodegenerative diseases. Amino acid and lipid metabolomic biomarkers associate with future type 2 diabetes mellitus ... Full text Open Access Link to item Cite

From Intention to Maintenance: A Two-Year Examination of Clinical and Lifestyle Changes in Rheumatoid Arthritis.

Journal Article ACR Open Rheumatol · December 2025 OBJECTIVE: To evaluate the long-term impacts of a 16-week remotely supervised exercise and weight loss intervention for rheumatoid arthritis (Supervised Weight Loss and Exercise Training in Rheumatoid Arthritis [SWET-RA]). METHODS: In total, 21 older adult ... Full text Open Access Link to item Cite
View All Publications

Recent Grants


A precision health approach to target exercise interventions for short- and long-term cardiometabolic health benefits

ResearchPrincipal Investigator · Awarded by American Heart Association · 2023 - 2026

Exercise-induced Legacy Health Benefits on Cardiometabolic Risk Factors in Aging Adults with Prediabetes

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2025

View All Grants

Education, Training & Certifications


University of South Carolina, Columbia · 2017 Ph.D.