Scholars@Duke
Lesley Skalla

Selected Publications

Management of Staphylococcus aureus Bacteremia: A Review.

Journal Article JAMA · September 2, 2025 IMPORTANCE: Staphylococcus aureus, a gram-positive bacterium, is the leading cause of death from bacteremia worldwide, with a case fatality rate of 15% to 30% and an estimated 300 000 deaths per year. OBSERVATIONS: Staphylococcus aureus bacteremia causes m ... Full text Link to item Cite

A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Complicated Intraabdominal Infections.

Journal Article Clin Infect Dis · August 6, 2025 BACKGROUND: In this systematic review, we assessed health-related quality-of-life (HRQoL) measures in patients with complicated intraabdominal infections (cIAIs) commonly associated with sepsis and evaluated the impact of cIAIs on HRQoL. METHODS: Following ... Full text Link to item Cite

A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia.

Journal Article Clin Infect Dis · August 6, 2025 BACKGROUND: We conducted a systematic review to gain insight into how health-related quality of life (HRQoL) is measured and reported in hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP), common causes of dis ... Full text Link to item Cite

A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Complicated Urinary Tract Infections.

Journal Article Clin Infect Dis · August 6, 2025 BACKGROUND: Complicated urinary tract infections (cUTIs) significantly affect patients' health-related quality of life (HRQoL), yet current end points defined by the United States Food and Drug Administration for antibiotic registrational trials fail to ca ... Full text Link to item Cite

A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Acute Bacterial Skin and Skin Structure Infections.

Journal Article Clin Infect Dis · August 6, 2025 BACKGROUND: Acute bacterial skin and skin structure infections (ABSSSIs) can diminish patients' health-related quality of life (HRQoL). We performed a systematic review to determine how HRQoL has been measured in patients with ABSSSIs. METHODS: We searched ... Full text Link to item Cite

Provider Perspectives on Implementation of Adult Community-Based Palliative Care: A Scoping Review.

Journal Article Med Care Res Rev · August 2025 While community-based palliative care (CBPC) programs have been expanding, there remain important obstacles to widespread use. Since provider perspectives on CBPC remain underexplored, we conducted a scoping review to summarize provider perspectives regard ... Full text Link to item Cite

Combination therapy with fosfomycin for Staphylococcus aureus bacteraemia or endocarditis: a systematic review and meta-analysis of randomized trials.

Journal Article JAC Antimicrob Resist · June 2025 BACKGROUND AND OBJECTIVES: Fosfomycin combination therapy for Staphylococcus aureus bacteraemia or endocarditis has been evaluated, but studies were limited by small sample sizes. We sought to conduct a systematic review and meta-analysis of randomized con ... Full text Link to item Cite

Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials.

Journal Article Clin Infect Dis · February 5, 2025 BACKGROUND: We conducted a systematic review of randomized, controlled trials (RCTs) to generate more precise estimates of the efficacy and safety of oral versus intravenous antibiotic therapy for Staphylococcus aureus bacteremia or endocarditis. METHODS: ... Full text Link to item Cite

IMPLEMENTATION OF COMMUNITY-BASED PALLIATIVE CARE: A SYSTEMATIC SCOPING REVIEW

Conference Innovation in Aging · December 31, 2024 AbstractCommunity-based palliative care (CBPC) models, which include palliative care (PC) delivered in outpatient clinics and homes, improve quality of life for people living with serious illness and their c ... Full text Cite

Standard Compared With Extended Red Blood Cell Antigen Matching for Prevention of Subsequent Hemolytic Disease of the Fetus and Newborn: A Systematic Review.

Journal Article Obstet Gynecol · October 1, 2024 OBJECTIVE: To systematically review and meta-analyze alloimmunization among recipients of red blood cells (RBCs) matched for ABO blood type and Rhesus D (ABO+D) antigen compared with those also matched for c, E, and Kell (cEK). DATA SOURCES: Four online da ... Full text Link to item Cite

Surgical Treatment of Severe Heterotopic Ossification After Total Hip Arthroplasty Over the Last 25 Years: A Systematic Review of the Literature and a New Case Series.

Journal Article J Arthroplasty · September 2024 BACKGROUND: Severe heterotopic ossification (HO) (grades III and IV) after total hip arthroplasty (THA) over the last 25 years requiring excision is very uncommon. We performed a systematic review of the literature and reported a new case series with opera ... Full text Link to item Cite

Use of Implementation Strategies to Promote the Uptake of Knee Osteoarthritis Practice Guidelines and Improve Patient Outcomes: A Systematic Review.

Journal Article Arthritis Care Res (Hoboken) · September 2024 OBJECTIVE: Translation of knee osteoarthritis (KOA) clinical practice guidelines (CPGs) to practice remains suboptimal. The primary purpose of this systematic review was to describe the use of implementation strategies to promote KOA CPG-recommended care. ... Full text Link to item Cite

The Landscape of Care for Women Veterans with Cancer: An Evidence Map.

Journal Article J Gen Intern Med · September 2024 BACKGROUND: Women are the fastest growing veteran group in the US and the number of women veterans (WVs) with cancer is rising; however, little is known about this population. Cancer care for WVs is complex and it is essential to understand their unique ne ... Full text Link to item Cite

Scoping review of percutaneous mechanical aspiration for valvular and cardiac implantable electronic device infective endocarditis.

Journal Article Clin Microbiol Infect · December 2023 BACKGROUND: Percutaneous mechanical aspiration (PMA) of intravascular vegetations is a novel strategy for management of patients with infective endocarditis (IE) who are at high risk of poor outcomes with conventional cardiac surgery. However, clear indica ... Full text Link to item Cite

Public reporting of black participation in anti-hypertensive drug clinical trials.

Journal Article Am Heart J · April 2023 BACKGROUND: Non-Hispanic Black people in the United States have the highest prevalence of essential hypertension. Unfortunately, clinical trials often underrepresent Black patients. We aim to understand whether trial sponsorship type is associated with rep ... Full text Link to item Cite

Regulation of glutathione synthesis in the rat testis.

Conference BIOLOGY OF REPRODUCTION · 2000 Cite

Annual changes in serum concentrations of prolactin in captive male black bears (Ursus americanus).

Journal Article Journal of reproduction and fertility · July 1995 Prolactin may be involved in the regulation of reproduction in black bears (Ursus americanus) as it is a mediator of photoperiodic changes in a number of species. The objectives of this study were to validate a radioimmunoassay to measure prolactin in bear ... Full text Cite

Impact of standard ABO and Rhesus D crossmatching versus extended red blood cell antigen matching (c, E and K) of donor blood on alloimmunization in adults of reproductive age.

Conference Impact of standard ABO and Rhesus D crossmatching versus extended red blood cell antigen matching (c, E and K) of donor blood on alloimmunization in adults of reproductive age. ... Cite