Jennifer Shiunroh Li | Scholars@Duke

Jennifer Shiunroh Li
Beverly C. Morgan, M.D., Distinguished Professor of Pediatric Cardiology in the School of Medicine

1. Pediatric hypertension and hyperlipidemia
2. Clinical trials in children with heart disease
3. Thrombosis in patients with congenital heart disease
4. Enzyme replacement in Pompe disease
5. Infective endocarditis

Office Hours

Current Appointments & Affiliations

Beverly C. Morgan, M.D., Distinguished Professor of Pediatric Cardiology in the School of Medicine, Pediatrics, Cardiology, Pediatrics 2012
Professor of Pediatrics, Pediatrics, Cardiology, Pediatrics 2008
Chief, Division of Pediatric Cardiology, Pediatrics, Cardiology, Pediatrics 2006
Professor of Medicine, Medicine, Cardiology, Medicine 2008
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 1999

Contact Information

1927C Childrens Hlth Ctr, Box 3090, Durham, NC 27710
1927C Childrens Hlth Ctr, Box 3090, Durham, NC 27710
li000001@mc.duke.edu (919) 684-3574

Background
Education, Training, & Certifications
- M.D., Duke University 1987
Duke Appointment History
- Medical Instructor in the Department of Medicine, Medicine, Cardiology, Medicine 1999 - 2008
- Associate Professor of Pediatrics, Pediatrics, Cardiology, Pediatrics 2005 - 2008
- Associate Professor of Pediatrics, Pediatrics, Cardiology, Pediatrics 2002 - 2005
- Assistant Professor of Pediatrics, Pediatrics, Cardiology, Pediatrics 1995 - 2002
- Associate in the Department of Medicine, Medicine, Clinical Science Departments 1995 - 1999
- Associate in the Department of Pediatrics, Pediatrics, Cardiology, Pediatrics 1993 - 1995
Recognition
In the News
- JUN 1, 2021 School of Medicine Magnify
  
  Asking New Questions in the Fight Against Childhood Obesity
- JUN 13, 2017 Duke Health News
  
  Duke Health Trials on Childhood Obesity Will Study Efficacy of Weight Loss Programs, Biomarkers of Obesity
Expertise
Global Scholarship
- Research
  - Kenya (Country)
Research
Selected Grants
- Duke-UNC Collaborative Pediatric Clinical Pharmacology Postdoctoral Training Program awarded by National Institutes of Health 2021 - 2026
- Duke Center for Advancement of Child Health (CAtCH). awarded by National Institutes of Health 2021 - 2026
- Parks & Pediatrics Fit Together: Translating knowledge into action for child obesity treatment in partnership with Parks and Recreation awarded by National Institutes of Health 2020 - 2025
- The North Carolina Congenital Heart Disease Surveillance Network awarded by Centers for Disease Control and Prevention 2019 - 2024
- The Colin's Kids Pediatric Cardiology Research Funds awarded by Colin's Kids, Inc. 2019 - 2024
- Pediatric Heart Network-SVRIII awarded by New England Research Institutes, Inc. 2017 - 2024
- Unified Program for Therapeutics in Children awarded by National Institutes of Health 2019 - 2024
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2003 - 2024
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (UL1) awarded by National Institutes of Health 2018 - 2023
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- Bridging the Gap to Enhance Clinical Research Program (BIGGER) awarded by National Institutes of Health 2016 - 2021
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2020 - 2021
- Leveraging registry resources for efficient and cost effective clinical trials awarded by National Institutes of Health 2016 - 2021
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2016 - 2021
- Grant- NU05DD004933 (Duke as a site #05) awarded by Centers for Disease Control and Prevention 2016 - 2020
- North Carolina Congenital Heart Defects Surveillance Network awarded by Centers for Disease Control and Prevention 2015 - 2020
- Echocardiogram to Diagnose Pulmonary Hypertension in Premature Infants awarded by University of North Carolina - Chapel Hill 2015 - 2019
- IMPROVING PATIENT AND FAMILY HEALTH USING FAMILY-CENTERED OUTCOMES AND SHARED DECISION MAKING awarded by University of Utah 2018 - 2019
- Duke CTSA (KL2) awarded by National Institutes of Health 2013 - 2018
- Duke CTSA (TL1) awarded by National Institutes of Health 2013 - 2018
- Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
- Duke CTSA (UL1) awarded by National Institutes of Health 2013 - 2018
- Safety, Pharmacokinetics (PK) and Hemodynamic Effects of Ambrisentan in Children with Single Ventricle Heart Defects. awarded by Gilead Sciences, Inc. 2015 - 2018
- Evaluation of endothelial function in single ventricle patients receiving Ambrisentan after surgery. awarded by Thrasher Research Fund 2015 - 2017
- Pediatric Heart Network awarded by New England Research Institutes, Inc. 2015 - 2017
- Pediatric Heart Network awarded by New England Research Institutes, Inc. 2011 - 2017
- Pediatric Heart Netwrok - Auxillary Site awarded by New England Research Institutes, Inc. 2015 - 2016
- The Duke Multidisciplinary Training Program in Pediatric Lung Disease awarded by National Institutes of Health 2010 - 2016
- Molecular Mechanisms of Thoracic Aortic Aneurysms awarded by Cincinnati Children's Hospital Medical Center 2014 - 2016
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2011 - 2016
- Pediatric Heart Netwrok awarded by New England Research Institutes, Inc. 2014 - 2015
- Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health 2010 - 2015
- Institutional Training Grant in Pediatric Cardiology awarded by National Institutes of Health 2009 - 2015
- Career Development in Outcomes Assessment in Congenital Heart Surgery awarded by National Institutes of Health 2010 - 2014
- CTSA UL awarded by National Institutes of Health 2006 - 2012
- Comparative Effectiveness of Medications Used in Congenital Heart Surgery awarded by National Institutes of Health 2009 - 2012
- Prevention of Cardiovascular Complications of Pediatric SLE awarded by National Institutes of Health 2002 - 2011
- Pediatric Heart Network North Carolina Consortium awarded by National Institutes of Health 2001 - 2011
- North Carolina Collaborative PPRU Network awarded by National Institutes of Health 2004 - 2010
- Best Pharmaceutical for Children Act (BPCA): Use of Meropenem in Infants awarded by National Institutes of Health 2007 - 2010
- NIH National Research Service Award Institutional Research Training Grant (T32) Duke Pediatric Cardiology awarded by National Institutes of Health 2004 - 2009
External Relationships
- American Board of Pediatrics
- Bayer Healthcare Pharmaceuticals, Germany
- Cytokinetics, Inc.
- Genzyme Corporation (Sanofi Aventis)
- Janssen Pharmaceuticals (Johnson & Johnson)
- W. L. Gore & Associates, Inc.
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Williams, Jason L., Rachel D. Torok, Alfred D’Ottavio, Tracy Spears, Karen Chiswell, Nina E. Forestieri, Charlie J. Sang, et al. “Causes of Death in Infants and Children with Congenital Heart Disease.” Pediatr Cardiol, April 22, 2021. https://doi.org/10.1007/s00246-021-02612-2.
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  - Hill, Kevin D., Anil R. Maharaj, Jennifer S. Li, Elizabeth Thompson, Piers C. A. Barker, and Christoph P. Hornik. “A Randomized, Controlled Pharmacokinetic and Pharmacodynamics Trial of Ambrisentan After Fontan Surgery.” Pediatr Crit Care Med 21, no. 9 (September 2020): e795–803. https://doi.org/10.1097/PCC.0000000000002410.
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  - McCrindle, Brian W., Cedric Manlhiot, Jane W. Newburger, Ashraf S. Harahsheh, Therese M. Giglia, Frederic Dallaire, Kevin Friedman, et al. “Medium-Term Complications Associated With Coronary Artery Aneurysms After Kawasaki Disease: A Study From the International Kawasaki Disease Registry.” J Am Heart Assoc 9, no. 15 (August 4, 2020): e016440. https://doi.org/10.1161/JAHA.119.016440.
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  - Armstrong, Sarah, Jennifer S. Li, and Asheley C. Skinner. “Flattening the (BMI) Curve: Timing of Child Obesity Onset and Cardiovascular Risk.” Pediatrics 146, no. 2 (August 2020). https://doi.org/10.1542/peds.2020-1353.
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  - Hill, Kevin D., H Scott Baldwin, David P. Bichel, Alicia M. Ellis, Eric M. Graham, Christoph P. Hornik, Jeffrey P. Jacobs, et al. “Overcoming underpowering: Trial simulations and a global rank end point to optimize clinical trials in children with heart disease.” Am Heart J 226 (August 2020): 188–97. https://doi.org/10.1016/j.ahj.2020.05.011.
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  - Sarno, Lauren A., Lindsay Cortright, Tiara Stanley, Dmitry Tumin, Jennifer S. Li, and Charlie J. Sang. “Clinical and socio-economic predictors of work participation in adult CHD patients.” Cardiol Young 30, no. 8 (August 2020): 1081–85. https://doi.org/10.1017/S1047951120001572.
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  - Goldstein, Sarah A., Alfred D’Ottavio, Tracy Spears, Karen Chiswell, Robert J. Hartman, Richard A. Krasuski, Alex R. Kemper, et al. “Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease.” J Am Heart Assoc 9, no. 14 (July 21, 2020): e016400. https://doi.org/10.1161/JAHA.119.016400.
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  - Van Driest, Sara L., Lynn A. Sleeper, Bruce D. Gelb, Shaine A. Morris, Harry C. Dietz, Geoffrey A. Forbus, Elizabeth Goldmuntz, et al. “Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.” J Pediatr 222 (July 2020): 213-220.e5. https://doi.org/10.1016/j.jpeds.2020.03.064.
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  - Armstrong, Sarah C., McAllister Windom, Nathan A. Bihlmeyer, Jennifer S. Li, Svati H. Shah, Mary Story, Nancy Zucker, et al. “Rationale and design of "Hearts & Parks": study protocol for a pragmatic randomized clinical trial of an integrated clinic-community intervention to treat pediatric obesity.” Bmc Pediatr 20, no. 1 (June 26, 2020): 308. https://doi.org/10.1186/s12887-020-02190-x.
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  - Corey, Kristin M., Michael Jay Campbell, Kevin D. Hill, Christoph P. Hornik, Richard Krasuski, Piers C. Barker, Robert D. B. Jaquiss, and Jennifer S. Li. “Pulmonary Valve Endocarditis: The Potential Utility of Multimodal Imaging Prior to Surgery.” World J Pediatr Congenit Heart Surg 11, no. 2 (March 2020): 192–97. https://doi.org/10.1177/2150135119896287.
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  - Hill, Kevin D., H Scott Baldwin, David P. Bichel, Ryan J. Butts, Reid C. Chamberlain, Alicia M. Ellis, Eric M. Graham, et al. “Rationale and design of the STeroids to REduce Systemic inflammation after infant heart Surgery (STRESS) trial.” Am Heart J 220 (February 2020): 192–202. https://doi.org/10.1016/j.ahj.2019.11.016.
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  - Goldstone, Andrew B., Michael Baiocchi, David Wypij, Christian Stopp, Dean B. Andropoulos, Joseph Atallah, Andrew M. Atz, et al. “The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants.” Eur J Cardiothorac Surg 57, no. 1 (January 1, 2020): 63–71. https://doi.org/10.1093/ejcts/ezz123.
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  - Goldberg, Caren S., Chenwei Hu, Cheryl Brosig, J William Gaynor, William T. Mahle, Thomas Miller, Kathleen A. Mussatto, et al. “Behavior and Quality of Life at 6 Years for Children With Hypoplastic Left Heart Syndrome.” Pediatrics 144, no. 5 (November 2019). https://doi.org/10.1542/peds.2019-1010.
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  - Sutton, Lynn, Lisa G. Berdan, Jean Bolte, Robert M. Califf, Geoffrey S. Ginsburg, Jennifer S. Li, Jonathan McCall, et al. “Facilitating translational team science: The project leader model.” J Clin Transl Sci 3, no. 4 (August 2019): 140–46. https://doi.org/10.1017/cts.2019.398.
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  - Boruta, Mary, Richard Boruta, and Jennifer Li. “Acid Suppression Therapy and Symptom Improvement (or Lack Thereof) in Children.” Pediatrics 144, no. 1 (July 2019). https://doi.org/10.1542/peds.2019-0909.
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  - Pina, Liza Miriam, Xiangwen Dong, Liping Zhang, Mahesh N. Samtani, Alan D. Michelson, Henri Justino, Damien Bonnet, et al. “Rivaroxaban, a direct Factor Xa inhibitor, versus acetylsalicylic acid as thromboprophylaxis in children post-Fontan procedure: Rationale and design of a prospective, randomized trial (the UNIVERSE study).” Am Heart J 213 (July 2019): 97–104. https://doi.org/10.1016/j.ahj.2019.04.009.
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  - Taylor-Zapata, Perdita, Carissa M. Baker-Smith, Gilbert Burckart, Stephen R. Daniels, Joseph T. Flynn, George Giacoia, Dionna Green, et al. “Research Gaps in Primary Pediatric Hypertension.” Pediatrics 143, no. 5 (May 2019). https://doi.org/10.1542/peds.2018-3517.
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  - McCrary, Andrew W., Piers C. A. Barker, Rachel D. Torok, Tracy G. Spears, Jennifer S. Li, Christoph P. Hornik, and Matthew M. Laughon. “Agreement of an echocardiogram-based diagnosis of pulmonary hypertension in infants at risk for bronchopulmonary dysplasia among masked reviewers.” J Perinatol 39, no. 2 (February 2019): 248–55. https://doi.org/10.1038/s41372-018-0277-6.
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  - Handisides, Jill C., Danielle Hollenbeck-Pringle, Karen Uzark, Felicia L. Trachtenberg, Victoria L. Pemberton, Teresa W. Atz, Timothy J. Bradley, et al. “Health-Related Quality of Life in Children and Young Adults with Marfan Syndrome.” J Pediatr 204 (January 2019): 250-255.e1. https://doi.org/10.1016/j.jpeds.2018.08.061.
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  - Hoskoppal, Arvind, Shaji Menon, Felicia Trachtenberg, Kristin M. Burns, Julie De Backer, Bruce D. Gelb, Marie Gleason, et al. “Predictors of Rapid Aortic Root Dilation and Referral for Aortic Surgery in Marfan Syndrome.” Pediatr Cardiol 39, no. 7 (October 2018): 1453–61. https://doi.org/10.1007/s00246-018-1916-6.
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  - Herbert, Mrudu, Heidi Cope, Jennifer S. Li, and Priya S. Kishnani. “Severe Cardiac Involvement Is Rare in Patients with Late-Onset Pompe Disease and the Common c.-32-13T>G Variant: Implications for Newborn Screening.” J Pediatr 198 (July 2018): 308–12. https://doi.org/10.1016/j.jpeds.2018.02.007.
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  - Torok, Rachel D., Jennifer S. Li, Prince J. Kannankeril, Andrew M. Atz, Raafat Bishai, Ellen Bolotin, Stefanie Breitenstein, et al. “Recommendations to Enhance Pediatric Cardiovascular Drug Development: Report of a Multi-Stakeholder Think Tank.” J Am Heart Assoc 7, no. 4 (February 10, 2018). https://doi.org/10.1161/JAHA.117.007283.
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  - Watt, Kevin M., Debbie Avant, Jennifer Sherwin, Daniel K. Benjamin, Christoph Hornik, Jennifer S. Li, and P Brian Smith. “Effect of renal function on antihypertensive drug safety and efficacy in children.” Pediatr Nephrol 33, no. 1 (January 2018): 139–46. https://doi.org/10.1007/s00467-017-3763-8.
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  - Hill, Kevin D., Chu Wang, Andrew J. Einstein, Natalie Januzis, Giao Nguyen, Jennifer S. Li, Gregory A. Fleming, and Terry K. Yoshizumi. “Impact of imaging approach on radiation dose and associated cancer risk in children undergoing cardiac catheterization.” Catheter Cardiovasc Interv 89, no. 5 (April 2017): 888–97. https://doi.org/10.1002/ccd.26630.
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  - Chu, Patricia Y., Jennifer S. Li, Andrzej S. Kosinski, Christoph P. Hornik, and Kevin D. Hill. “Congenital Heart Disease in Premature Infants 25-32 Weeks' Gestational Age.” J Pediatr 181 (February 2017): 37-41.e1. https://doi.org/10.1016/j.jpeds.2016.10.033.
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  - Chu, Patricia Y., Christoph P. Hornik, Jennifer S. Li, Michael J. Campbell, and Kevin D. Hill. “Respiratory syncytial virus hospitalisation trends in children with haemodynamically significant heart disease, 1997-2012.” Cardiol Young 27, no. 1 (January 2017): 16–25. https://doi.org/10.1017/S1047951116000470.
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  - Mori, Mari, Lauren A. Bailey, Januario Estrada, Catherine W. Rehder, Jennifer S. Li, Joseph G. Rogers, Deeksha S. Bali, Anne F. Buckley, and Priya S. Kishnani. “Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.” Jimd Rep 31 (2017): 79–83. https://doi.org/10.1007/8904_2016_563.
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  - Hill, Kevin D., and Jennifer S. Li. “Childhood Hypertension: An Underappreciated Epidemic?” Pediatrics 138, no. 6 (December 2016). https://doi.org/10.1542/peds.2016-2857.
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  - Hornik, Christoph P., Eric M. Graham, Kevin Hill, Jennifer S. Li, George Ofori-Amanfo, Reese H. Clark, and P Brian Smith. “Cardiopulmonary resuscitation in hospitalized infants.” Early Hum Dev 101 (October 2016): 17–22. https://doi.org/10.1016/j.earlhumdev.2016.03.015.
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  - Plummer, Sarah T., Christoph P. Hornik, Hamilton Baker, Gregory A. Fleming, Susan Foerster, M Eric Ferguson, Andrew C. Glatz, et al. “Maladaptive aortic properties after the Norwood procedure: An angiographic analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial.” J Thorac Cardiovasc Surg 152, no. 2 (August 2016): 471-479.e3. https://doi.org/10.1016/j.jtcvs.2016.03.091.
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  - Hartz, Jacob, Jennifer S. Li, Ololade O. Akintoye, and Christoph P. Hornik. “Clinicians' Adherence to Guidelines on Evaluation of Hypertension in Children and Adolescents.” World J Pediatr Congenit Heart Surg 7, no. 4 (July 2016): 440–45. https://doi.org/10.1177/2150135116641877.
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  - Uzark, Karen, Victor Zak, Peter Shrader, Brian W. McCrindle, Elizabeth Radojewski, James W. Varni, Kaitlyn Daniels, et al. “Assessment of Quality of Life in Young Patients with Single Ventricle after the Fontan Operation.” J Pediatr 170 (March 2016): 166-72.e1. https://doi.org/10.1016/j.jpeds.2015.11.016.
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  - Hill, Kevin D., Mario R. Sampson, Jennifer S. Li, Robert D. Tunks, Scott R. Schulman, and Michael Cohen-Wolkowiez. “Pharmacokinetics of intravenous sildenafil in children with palliated single ventricle heart defects: effect of elevated hepatic pressures.” Cardiol Young 26, no. 2 (February 2016): 354–62. https://doi.org/10.1017/S1047951115000359.
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  - Chu, Patricia Y., Jennifer S. Li, Andrzej S. Kosinski, Christoph P. Hornik, and Kevin D. Hill. “Epidemiology and Mortality of Very and Extremely Preterm Infants With Congenital Heart Defects.” Circulation 132 (November 10, 2015).
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  - Mahle, William T., Anne M. Murphy, Jennifer S. Li, Yuk M. Law, Jane W. Newburger, Stephen R. Daniels, Daniel Bernstein, Bradley S. Marino, and Robert D. Ross. “Task Force 8: Pediatric Cardiology Fellowship Training in Research and Scholarly Activity.” J Am Coll Cardiol 66, no. 6 (August 11, 2015): 740–47. https://doi.org/10.1016/j.jacc.2015.03.006.
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  - Mahle, William T., Anne M. Murphy, Jennifer S. Li, Yuk M. Law, Jane W. Newburger, Stephen R. Daniels, Daniel Bernstein, et al. “Task Force 8: Pediatric Cardiology Fellowship Training in Research and Scholarly Activity. SPCTPD/ACC/AAP/AHA.” Circulation 132, no. 6 (August 11, 2015): e107–13. https://doi.org/10.1161/CIR.0000000000000199.
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  - Gaynor, J William, Christian Stopp, David Wypij, Dean B. Andropoulos, Joseph Atallah, Andrew M. Atz, John Beca, et al. “Neurodevelopmental outcomes after cardiac surgery in infancy.” Pediatrics 135, no. 5 (May 2015): 816–25. https://doi.org/10.1542/peds.2014-3825.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Response to letters regarding article, "Cumulative radiation exposure and cancer risk estimation in children with heart disease".” Circulation 131, no. 16 (April 21, 2015): e419–20. https://doi.org/10.1161/CIRCULATIONAHA.114.013266.
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  - Bloomfield, Gerald S., Tracy Y. Wang, L Ebony Boulware, Robert M. Califf, Adrian F. Hernandez, Eric J. Velazquez, Eric D. Peterson, and Jennifer S. Li. “Implementation of management strategies for diabetes and hypertension: from local to global health in cardiovascular diseases.” Glob Heart 10, no. 1 (March 2015): 31–38. https://doi.org/10.1016/j.gheart.2014.12.010.
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  - Plummer, Sarah T., Christoph P. Hornik, Hamilton Baker, Gregory A. Fleming, Susan Foerster, Eric Ferguson, Andrew Glatz, et al. “Maladaptive Aortic Properties after the Norwood Procedure: an Angiographic Analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial.” Circulation 130 (November 25, 2014).
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  - Hill, Kevin D., Jennifer S. Li, and Christoph P. Hornik. “Pediatric exclusivity and other contemporary regulatory initiatives: aligning financial incentives with the needs of our patients.” Clinical Investigation 4, no. 11 (November 2014): 989–91. https://doi.org/10.4155/cli.14.82.
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  - Pasquali, Sara K., Xia He, Marshall L. Jacobs, Samir S. Shah, Eric D. Peterson, Michael G. Gaies, Matthew Hall, et al. “Excess costs associated with complications and prolonged length of stay after congenital heart surgery.” Ann Thorac Surg 98, no. 5 (November 2014): 1660–66. https://doi.org/10.1016/j.athoracsur.2014.06.032.
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  - McCrindle, Brian W., Jennifer S. Li, Cedric Manlhiot, James S. Tweddell, Therese M. Giglia, M Patricia Massicotte, Paul Monagle, et al. “Challenges and priorities for research: a report from the National Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH) Working Group on thrombosis in pediatric cardiology and congenital heart disease.” Circulation 130, no. 14 (September 30, 2014): 1192–1203. https://doi.org/10.1161/CIRCULATIONAHA.113.008428.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry T. Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cumulative radiation exposure and cancer risk estimation in children with heart disease.” Circulation 130, no. 2 (July 8, 2014): 161–67. https://doi.org/10.1161/CIRCULATIONAHA.113.005425.
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  - Burch, Phillip T., Eric Gerstenberger, Chitra Ravishankar, David A. Hehir, Ryan R. Davies, Steven D. Colan, Lynn A. Sleeper, et al. “Longitudinal assessment of growth in hypoplastic left heart syndrome: results from the single ventricle reconstruction trial.” J Am Heart Assoc 3, no. 3 (June 23, 2014): e000079. https://doi.org/10.1161/JAHA.114.000079.
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  - Hill, Kevin D., Karen Chiswell, Robert M. Califf, Gail Pearson, and Jennifer S. Li. “Characteristics of pediatric cardiovascular clinical trials registered on ClinicalTrials.gov.” Am Heart J 167, no. 6 (June 2014): 921-9.e2. https://doi.org/10.1016/j.ahj.2014.02.002.
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  - Pasquali, Sara K., Marshall L. Jacobs, Xia He, Samir S. Shah, Eric D. Peterson, Matthew Hall, J William Gaynor, et al. “Variation in congenital heart surgery costs across hospitals.” Pediatrics 133, no. 3 (March 2014): e553–60. https://doi.org/10.1542/peds.2013-2870.
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  - Tunks, Robert D., Piers C. A. Barker, Daniel K. Benjamin, Michael Cohen-Wolkowiez, Gregory A. Fleming, Matthew Laughon, Jennifer S. Li, and Kevin D. Hill. “Sildenafil exposure and hemodynamic effect after Fontan surgery.” Pediatr Crit Care Med 15, no. 1 (January 2014): 28–34. https://doi.org/10.1097/PCC.0000000000000007.
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  - Hill, Kevin D., John F. Rhodes, Ranjit Aiyagari, G Hamilton Baker, Lisa Bergersen, Paul J. Chai, Gregory A. Fleming, et al. “Intervention for recoarctation in the single ventricle reconstruction trial: incidence, risk, and outcomes.” Circulation 128, no. 9 (August 27, 2013): 954–61. https://doi.org/10.1161/CIRCULATIONAHA.112.000488.
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  - Pasquali, Sara K., Xia He, Marshall L. Jacobs, Matthew Hall, J William Gaynor, Samir S. Shah, Eric D. Peterson, Kevin D. Hill, Jennifer S. Li, and Jeffrey P. Jacobs. “Hospital variation in postoperative infection and outcome after congenital heart surgery.” Ann Thorac Surg 96, no. 2 (August 2013): 657–63. https://doi.org/10.1016/j.athoracsur.2013.04.024.
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  - Hill, Kevin D., Robert D. Tunks, Piers C. A. Barker, Daniel K. Benjamin, Michael Cohen-Wolkowiez, Gregory A. Fleming, Matthew Laughon, and Jennifer S. Li. “Sildenafil exposure and hemodynamic effect after stage II single-ventricle surgery.” Pediatr Crit Care Med 14, no. 6 (July 2013): 593–600. https://doi.org/10.1097/PCC.0b013e31828aa5ee.
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  - Wessel, David L., Felix Berger, Jennifer S. Li, Ingo Dähnert, Amit Rakhit, Sylvie Fontecave, Jane W. Newburger, and Jane W. CLARINET Investigators. “Clopidogrel in infants with systemic-to-pulmonary-artery shunts.” N Engl J Med 368, no. 25 (June 20, 2013): 2377–84. https://doi.org/10.1056/NEJMoa1114588.
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  - Li, Jennifer S., Tracie A. Barnett, Elizabeth Goodman, Richard C. Wasserman, Alex R. Kemper, and Alex R. American Heart Association Atherosclerosis, Hypertension and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young, Council on Epidemiology and Prevention, and Council on Nutrition, Physical Activity and Metabolism. “Approaches to the prevention and management of childhood obesity: the role of social networks and the use of social media and related electronic technologies: a scientific statement from the American Heart Association.” Circulation 127, no. 2 (January 15, 2013): 260–67. https://doi.org/10.1161/CIR.0b013e3182756d8e.
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  - Pasquali, Sara K., Eric D. Peterson, Jeffrey P. Jacobs, Xia He, Jennifer S. Li, Marshall L. Jacobs, J William Gaynor, Jennifer C. Hirsch, Samir S. Shah, and John E. Mayer. “Differential case ascertainment in clinical registry versus administrative data and impact on outcomes assessment for pediatric cardiac operations.” Ann Thorac Surg 95, no. 1 (January 2013): 197–203. https://doi.org/10.1016/j.athoracsur.2012.08.074.
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  - Hill, Kevin D., John F. Rhodes, Ranjit Aiyagari, G. H. Baker, Lisa Bergersen, Paul J. Chai, Gregory A. Fleming, et al. “Intervention for Re-coarctation in the Single Ventricle Reconstruction Trial: Incidence, Risk and Outcomes.” Circulation 126, no. 21 (November 20, 2012).
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  - Hill, Kevin D., Robert Tunks, Gregory A. Fleming, John F. Rhodes, Matthew Laughon, Michael Cohen-Wolkowiez, and Jennifer S. Li. “Sildenafil Pharmacokinetics, Hemodynamic Efficacy and Safety after Stage II Single Ventricle Surgery.” Circulation 126, no. 21 (November 20, 2012).
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Sara K. Pasquali, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cancer Risk Estimation from Cardiac Catheterization in Children with Heart Disease.” Circulation 126, no. 21 (November 20, 2012).
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  - Pasquali, Sara K., Wendy K. Lam, Karen Chiswell, Alex R. Kemper, and Jennifer S. Li. “Status of the pediatric clinical trials enterprise: an analysis of the US ClinicalTrials.gov registry.” Pediatrics 130, no. 5 (November 2012): e1269–77. https://doi.org/10.1542/peds.2011-3565.
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  - Bates, Katherine E., Victoria L. Vetter, Jennifer S. Li, Susan Cummins, Fernando Aguel, Christopher Almond, Anne M. Dubin, et al. “Pediatric cardiovascular safety: challenges in drug and device development and clinical application.” Am Heart J 164, no. 4 (October 2012): 481–92. https://doi.org/10.1016/j.ahj.2012.07.019.
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  - LI, J. S., A. R. BENGUR, M. KAPPELER, W. NESMITH, and R. M. UNGERLEIDER. “DOPPLER DETERMINATION OF LEFT-VENTRICULAR DIASTOLIC DYSFUNCTION PREDICTS OUTCOME IN NEONATAL CONGENITAL HEART-DISEASE FOLLOWING REPAIR OR PALLIATION.” Circulation 92, no. 8 (October 15, 1995): 2781–2781.
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  - Herlong, J. R., J. S. Li, A. R. Bengur, and R. M. Ungerleider. “Pulmonary vein Doppler echocardiography after left atrial operation.” Ann Thorac Surg 60, no. 3 (September 1995): 678–80. https://doi.org/10.1016/0003-4975(95)00309-9.
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  - Zreik, H., A. R. Bengur, J. N. Meliones, D. Hansell, and J. S. Li. “Superior vena cava obstruction after extracorporeal membrane oxygenation.” J Pediatr 127, no. 2 (August 1995): 314–16. https://doi.org/10.1016/s0022-3476(95)70319-5.
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  - Campbell, P. T., J. S. Li, T. C. Wall, C. M. O’Connor, P. Van Trigt, R. T. Kenney, O. Melhus, and G. R. Corey. “Cytomegalovirus pericarditis: a case series and review of the literature.” Am J Med Sci 309, no. 4 (April 1995): 229–34. https://doi.org/10.1097/00000441-199504000-00009.
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  - Li, J. S., A. R. Snider, H. Zreik, B. E. Armstrong, J. W. Nesmith, and A. R. Bengur. “Relation of left ventricular mass, volume and mass/volume ratio in children with aortic stenosis and/or insufficiency.” Cardiology in the Young 5, no. 2 (January 1, 1995): 105–9. https://doi.org/10.1017/S1047951100011653.
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  - Li, J., J. K. Harrison, M. P. O’Laughlin, T. M. Bashore, and A. Garson. “Adult patients with congenital heart disease.” N C Med J 55, no. 4 (April 1994): 147–48.
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  - Kenney, R. T., J. S. Li, W. A. Clyde, T. C. Wall, C. M. O’Connor, P. T. Campbell, P. Van Trigt, and G. R. Corey. “Mycoplasmal pericarditis: evidence of invasive disease.” Clin Infect Dis 17 Suppl 1 (August 1993): S58–62. https://doi.org/10.1093/clinids/17.supplement_1.s58.
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  - RAYMOND, J. R., J. W. REGAN, R. E. BEACH, J. S. LI, V. W. DENNIS, and R. J. LEFKOWITZ. “ENRICHMENT OF ALPHA2-ADRENERGIC RECEPTORS OF RABBIT PROXIMAL TUBULE BASOLATERAL MEMBRANES (BLM).” Kidney International 31, no. 1 (January 1, 1987): 178–178.
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- Book Sections
  - Hill, K. D., R. D. Török, R. J. Portman, and J. S. Li. “Changes in drug development regulations and their impact on clinical trials.” In Pediatric Hypertension, 841–52, 2018. https://doi.org/10.1007/978-3-319-31107-4_38.
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  - Camitta, M. G. W., J. W. S. Geme, and J. S. Li. “Diagnosis and management of infective endocarditis.” In Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care, 2307–27, 2014. https://doi.org/10.1007/978-1-4471-4619-3_4.
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  - Hill, K. D., R. J. Portman, and J. S. Li. “Changes in pediatric food and drug administration written requests and regulations: Impact on clinical trial of hypertension trials in children.” In Pediatric Hypertension: Third Edition, 573–82, 2013. https://doi.org/10.1007/978-1-62703-490-6_38.
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  - Hill, K. D., and J. S. Li. “Conducting Clinical Trials in Developing and Emerging Countries: Review and Case Study.” In Pediatric Drug Development: Concepts and Applications, 477–81, 2013. https://doi.org/10.1002/9781118312087.ch38.
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- Other Articles
  - Pasquali, S. K., M. Hall, J. S. Li, E. D. Peterson, J. Jaggers, A. J. Lodge, J. P. Jacobs, M. L. Jacobs, and S. S. Shah. “Safety of aprotinin in congenital heart operations: Results from a large multicenter database.” Pediatric Cardiology, January 1, 2010. https://doi.org/10.1007/s00246-010-9792-8.
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- Conference Papers
  - Manlhiot, Cedric, Jane W. Newburger, Tisiana Low, Nagib Dahdah, Andrew S. Mackie, Geetha Raghuveer, Therese M. Giglia, et al. “Low-Molecular-Weight Heparin vs Warfarin for Thromboprophylaxis in Children With Coronary Artery Aneurysms After Kawasaki Disease: A Pragmatic Registry Trial.” In Can J Cardiol, 36:1598–1607, 2020. https://doi.org/10.1016/j.cjca.2020.01.016.
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  - Gabaldon, Josi R., Alexandra R. Zizzi, Alyssa M. Zidek, Jonathan D. Kenyon, Julie Counts, Leanna M. Ross, Ashley C. Skinney, Jennifer S. Li, William E. Kraus, and Sarah C. Armstrong. “Distribution Of Cardiorespiratory Fitness Among Children In The Hearts And Parks Study.” In Medicine and Science in Sports and Exercise, 52:473–473, 2020.
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  - Kenyon, Jonathan D., Alyssa M. Zidek, Josi R. Gabaldon, Alexandra R. Zizzi, Julie D. Counts, Leanna M. Ross, Cameron S. Catherine, et al. “Changes In Cardiorespiratory Fitness Among Children In The Hearts And Parks Heathy Lifestyle Intervention.” In Medicine and Science in Sports and Exercise, 52:63–63, 2020.
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  - Goldstein, Sarah A., Alfred D’Ottavio, Tracy Spears, Karen Chiswell, Manuela Wiedemeier, Toi D. Spates, Richard A. Krasuski, et al. “Causes of Death in Adults With Congenital Heart Disease Differ by Lesion Severity.” In Circulation, Vol. 138, 2018.
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  - Hill, Kevin D., Anil Maharaj, Elizabeth Thompson, Jennifer S. Li, Elliott Pearson, and Christoph Hornik. “A Double Blind, Randomized, Controlled Pharmacokinetic and Pharmacodynamics Trial of Ambrisentan After Fontan Surgery.” In Circulation, Vol. 138, 2018.
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  - Watkins, Stephanie E., Alex R. Kemper, Alfred D’Ottavio, Manuela Wiedemeier, Robert Meyer, Nathaniel Greene, Timothy M. Hoffman, et al. “Third Grade Academic Performance and Episodes of Care Among Children With Congenital Heart Defects.” In Circulation, Vol. 138, 2018.
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  - Newburger, Jane W., Lynn A. Sleeper, J William Gaynor, Danielle Hollenbeck-Pringle, Peter C. Frommelt, Jennifer S. Li, William T. Mahle, et al. “Transplant-Free Survival and Interventions at 6 Years in the SVR Trial.” In Circulation, 137:2246–53, 2018. https://doi.org/10.1161/CIRCULATIONAHA.117.029375.
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  - Hill, Kevin D., Sean O’Brien, H Scott Baldwin, David Bichel, Christoph Hornik, Jeffrey Jacobs, Marshall Jacobs, et al. “Overcoming Underpowering: Simulation Study to Evaluate an STS Global Rank Endpoint for Trials in Congenital Heart Surgery.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Li, Jennifer S., Kevin D. Hill, Christoph P. Hornik, Richard A. Krasuski, Piers C. Barker, Robert D. Jaquiss, and Michael J. Campbell. “Utility of Multi-modal Imaging in the Diagnosis of Pulmonary Valve Endocarditis.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - International Cardiac Collaborative on Neurodevelopment (ICCON) Investigators, Douglas A. “Impact of Operative and Postoperative Factors on Neurodevelopmental Outcomes After Cardiac Operations.” In Ann Thorac Surg, 102:843–49, 2016. https://doi.org/10.1016/j.athoracsur.2016.05.081.
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  - Hill, Kevin D., Heather T. Henderson, Christoph P. Hornik, and Jennifer S. Li. “Paediatric cardiovascular clinical trials: an analysis of ClinicalTrials.gov and the Food and Drug Administration Pediatric Drug Labeling Database.” In Cardiol Young, 25 Suppl 2:172–80, 2015. https://doi.org/10.1017/S1047951115000980.
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  - Chu, Patricia Y., Christoph P. Hornik, Jennifer S. Li, Michael J. Campbell, and Kevin D. Hill. “National Trends in RSV Hospitalizations in Children With Hemodynamically Significant Heart Disease, 1997-2009.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Hornik, Christoph P., Patricia Y. Chu, Jennifer S. Li, Reese H. Clark, Phillip Brian Smith, and Kevin D. Hill. “Comparative effectiveness of digoxin and propranolol for supraventricular tachycardia in infants.” In Pediatr Crit Care Med, 15:839–45, 2014. https://doi.org/10.1097/PCC.0000000000000229.
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  - Hill, Kevin D., Christoph P. Hornik, Jennifer S. Li, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Jason Johnson. “Radiation Exposure and Estimated Lifetime Attributable Risk of Cancer From Cardiac Catheterization in Children.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Pasquali, Sara K., Xia He, Marshall L. Jacobs, Samir S. Shah, Eric D. Peterson, Matthew Hall, J. W. Gaynor, et al. “Excess Costs Attributable to Complications and Prolonged Length of Stay Following Congenital Heart Surgery.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Pasquali, Sara K., Xia He, Marshall Jacobs, Samir Shah, Eric D. Peterson, Matthew Hall, J William Gaynor, et al. “HOSPITAL COSTS FOR PEDIATRIC HEART SURGERY VARY WIDELY ACROSS INSTITUTIONS.” In Journal of the American College of Cardiology, 61:E501–E501. Elsevier BV, 2013. https://doi.org/10.1016/s0735-1097(13)60501-x.
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  - Hornik, Christoph P., Jeffrey P. Jacobs, Xia He, Audra Hodges, Robert D. B. Jaquiss, Marshall L. Jacobs, Jennifer S. Li, Sean M. O’Brien, Eric D. Peterson, and Sara K. Pasquali. “PREVALENCE AND MORTALITY RISK ASSOCIATED WITH POST-OPERATIVE COMPLICATIONS FOLLOWING THE NORWOOD OPERATION: ANALYSIS OF A NATIONAL CLINICAL DATABASE.” In Journal of the American College of Cardiology, 57:E449–E449. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60449-x.
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  - Pasquali, Sara K., Jennifer S. Li, Xia He, Audra Hodges, Christoph P. Hornik, Robert D. B. Jaquiss, Marshall L. Jacobs, Sean M. O’Brien, Eric D. Peterson, and Jeffrey P. Jacobs. “PATIENT RISK STATUS, CENTER VOLUME AND OUTCOME FOLLOWING THE NORWOOD OPERATION.” In Journal of the American College of Cardiology, 57:E406–E406. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60406-3.
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  - Pasquali, Sara K., Matthew Hall, Jennifer S. Li, Eric D. Peterson, James Jaggers, Andrew J. Lodge, Bradley S. Marino, Denise M. Goodman, and Samir S. Shah. “Corticosteroids Are Associated With Increased Morbidity in Children Undergoing Congenital Heart Surgery.” In Circulation, 120:S567–S567. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Pasquali, Sara K., Matthew Hall, Jennifer S. Li, Eric D. Peterson, James Jaggers, Andrew J. Lodge, Jeffrey P. Jacobs, Marshall L. Jacobs, and Samir S. Shah. “Aprotinin is Not Associated With Renal Failure or Increased Mortality in Children Undergoing Congenital Heart Surgery.” In Circulation, 120:S574–S574. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Baker-Smith, Carissa M., Daniel K. Benjamin, Dianne Murphy, Eric L. Eisenstein, and Jennifer S. Li. “The economic return of performing pediatric anti-hypertensive drug clinical trials.” In Circulation, 116:822–822. LIPPINCOTT WILLIAMS & WILKINS, 2007.
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  - Li, Jennifer S., P Brian Smith, M Dianne Murphy, Robert M. Califf, and Daniel K. Benjamin. “Racial differences in blood pressure response to angiotensin converting enzyme inhibitors in children: An analysis of 6 pediatric hypertension trials.” In Circulation, 116:614–614. LIPPINCOTT WILLIAMS & WILKINS, 2007.
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  - Ansong, Annette K., Eric Yow, Katherine Berezny, Jutta von Stieglitz, and Jennifer S. Li. “Age at bidirectional glenn procedure and mortality: A multi-center, international registry.” In Journal of the American College of Cardiology, 49:267A-267A. ELSEVIER SCIENCE INC, 2007.
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  - Li, J. S., E. Yow, K. Y. Berezny, P. M. Bokesch, J. R. Charpie, J. P. Saul, B. Stos, et al. “Clinical outcome of palliative surgery including a systemic-to-pulmonary artery shunt in infants with cyanotic congenital heart disease: Results of a multi-center, international registry.” In Circulation, 112:U576–77. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Li, J. S., K. Y. Berezny, E. Yow, P. M. Bokesch, J. R. Charpie, G. A. Forbus, B. Stos, et al. “Influence of aspirin use on mortality in infants with cyanotic congenital heart disease palliated with a systemic-to-pulmonary artery shunt: A multi-center, international registry.” In Circulation, 112:U480–U480. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Newburger, J. W., L. A. Sleeper, B. W. McCrindle, L. L. Minich, W. Gersony, V. L. Vetter, A. M. Atz, et al. “Randomized trial of pulse steroid therapy in Kawasaki disease.” In Circulation, 112:U479–U479. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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  - Ansong, A. K., P. Kishnani, S. DeArmey, J. Mackey, R. J. Ing, E. Nozik-Grayck, S. F. Idriss, R. J. Kanter, Y. T. Chen, and J. S. Li. “Electrocardiographic response to enzyme replacement therapy for infantile Pompe disease.” In Circulation, 110:761–761. LIPPINCOTT WILLIAMS & WILKINS, 2004.
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  - Li, J. S., R. J. Ing, E. Nozik-Grayck, H. Rice, R. M. Kravitz, S. DeArmey, J. Mackey, A. Amalfitano, Y. T. Chen, and P. Kishnani. “Cardiac remodeling and clinical effects of recombinant human acid alpha-glucosidase enzyme replacement therapy for infantile glycogen storage disease type II.” In Circulation, 110:620–620. LIPPINCOTT WILLIAMS & WILKINS, 2004.
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  - McCrindle, B. W., R. V. Williams, P. D. Mitchell, D. T. Hsu, S. M. Paridon, A. M. Atz, J. S. Li, and J. W. Newburger. “The relationship of medical and patient characteristics to health-related quality of life in adolescents after the Fontan procedure.” In Circulation, 110:441–441. LIPPINCOTT WILLIAMS & WILKINS, 2004.
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  - Kay, Joseph D., Rakhi Kilaru, Katherine Berezny, David Deitchman, and Jennifer S. Li. “1114-205 Racial differences in blood pressure response in children with hypertension treated with fosinopril.” In Journal of the American College of Cardiology, 43:A387–A387. Elsevier BV, 2004. https://doi.org/10.1016/s0735-1097(04)91638-5.
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  - Li, Jennifer S., Katherine Y. Berezny, Rakhi Kilaru, Lydia Hazen, Ronald Portman, Ronald Hogg, Randall Jenkins, et al. “1085-167 Dose-response study of the efficacy and safety of fosinopril in children with hypertension: A randomized, double-blind, placebo-controlled, multicenter clinical trial.” In Journal of the American College of Cardiology, 43:A482–A482. Elsevier BV, 2004. https://doi.org/10.1016/s0735-1097(04)92039-6.
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  - Pasquali, S. K., V. Hasselblad, J. S. Li, D. F. Kong, and S. P. Sanders. “Coronary artery pattern and mortality following arterial switch operation for transposition of the great arteries: A meta-analysis.” In Circulation, 106:717–18. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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  - Li, J. S., S. P. Sanders, A. E. Perry, S. S. Stinnett, E. M. Darling, R. M. Ungerleider, J. Jaggers, P. Bokesch, A. Wheeler, and P. A. W. Anderson. “Pharmacokinetics, efficacy, and safety of TP10, soluble complement receptor 1, in infants undergoing cardiopulmonary bypass.” In Circulation, 102:599–599. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Campbell, M. J., P. Barker, S. Darty, J. Li, R. Kim, S. Pasquali, S. DeArmey, and P. Kishnani. “MRI assessment of left ventricular structure and function in children with infantile Pompe Disease,” n.d.
  - Campbell, M. J., P. Barker, S. Darty, J. Li, R. Kim, S. Pasquali, S. DeArmey, and P. Kishnani. “MRI assessment of left ventricular structure and function in children with infantile Pompe Disease,” n.d.
  - Campbell, M. J., P. Barker, and J. S. Li. “Utility of Adenosine Cardiac Stress MRI to Evaluate Ischemia in Patients with Kawasaki Disease,” n.d.
  - Chu, P., C. Hornik, J. S. Li, M. J. Campbell, and K. D. Hill. “National Trends in RSV Hospitalization in Children with Hemodynamically Significant Heart Disease, 1997-2009,” n.d.
Scholarly, Clinical, & Service Activities
Service to the Profession
- Chair, Sub Board of Pediatric Cardiology. American Board of Pediatrics. 2016 - 2017 2016 - 2017

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Education, Training, & Certifications

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Service to the Profession