Overview
Coordinating Centers, Pragmatic Clinical Research, Real World Evidence, Neurocognitive Data, Data Science Workforce Development
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2025 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute
·
2021 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Evaluating Social Determinants of Health-Based Alternatives to Race-Based Cognitive Normative Models.
Journal Article Neurology · December 2024 Background and objectivesRace and ethnicity are proxy measures of sociocultural factors that influence cognitive test performance. Our objective was to compare different regression-based cognitive normative models adjusting for demographics and di ... Full text CiteMultiply robust estimation of principal causal effects with noncompliance and survival outcomes.
Journal Article Clin Trials · October 2024 Treatment noncompliance and censoring are two common complications in clinical trials. Motivated by the ADAPTABLE pragmatic clinical trial, we develop methods for assessing treatment effects in the presence of treatment noncompliance with a right-censored ... Full text Link to item CiteAspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Male and Female Patients: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial.
Journal Article JAMA cardiology · September 2024 ImportanceAtherosclerotic cardiovascular disease (ASCVD) remains the leading cause of morbidity and mortality in the US. Although aspirin is recommended for secondary prevention of ASCVD, there was no difference in safety and effectiveness of aspi ... Full text CiteRecent Grants
The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2029Integrated Biostatistical Training for CVD Research
Inst. Training Prgm or CMEMentor · Awarded by North Carolina State University · 2022 - 2027Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
ResearchPrincipal Investigator · Awarded by Massachusetts General Hospital · 2019 - 2025View All Grants
Education, Training & Certifications
Harvard University, T.H. Chan School of Public Health ·
2004
Ph.D.