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Lisa Wruck

Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Durham Center, DUMC #3850, 300 West Morgan Street, Suite 800, Durham, NC 27701
P. O. Box 17969, 300 West Morgan Street, Suite 800, Durham, NC 27715

Overview


Coordinating Centers, Pragmatic Clinical Research, Real World Evidence, Neurocognitive Data, Data Science Workforce Development

Current Appointments & Affiliations


Professor of Biostatistics & Bioinformatics · 2025 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute · 2021 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Prevalence of pre-stroke and stroke-related vision impairments and their association with mild cognitive impairment and dementia.

Journal Article J Alzheimers Dis · December 12, 2025 BackgroundVision impairment is a risk factor for mild cognitive impairment (MCI) among stroke survivors, but it is unclear if this association is driven by vision impairment present before or due to the stroke, and if similar associations exist with dement ... Full text Link to item Cite

Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Chronic Obstructive Pulmonary Disease and Asthma: Insights From ADAPTABLE.

Journal Article J Am Heart Assoc · December 2, 2025 BACKGROUND: Guidelines recommend aspirin (75-100 mg daily) for the secondary prevention of atherosclerotic cardiovascular disease (ASCVD). However, it is unknown if people with a history of ASCVD and chronic obstructive pulmonary disease (COPD) or asthma, ... Full text Link to item Cite

Patient-directed data capture for clinical research: A pilot study testing two platforms.

Journal Article Contemp Clin Trials · December 2025 BACKGROUND: Patient-directed data capture enables individuals to access and share their electronic health record (EHR) data, potentially supporting patient engagement while also reducing data fragmentation. Although many vendors offer patient-directed data ... Full text Link to item Cite
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Recent Grants


The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2029

Integrated Biostatistical Training for CVD Research

Inst. Training Prgm or CMEMentor · Awarded by North Carolina State University · 2022 - 2027

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

ResearchPrincipal Investigator · Awarded by Massachusetts General Hospital · 2019 - 2026

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Education, Training & Certifications


Harvard University, T.H. Chan School of Public Health · 2004 Ph.D.