Current Appointments & Affiliations
Assistant Professor of Pediatrics
·
2024 - Present
Pediatrics, Critical Care Medicine,
Pediatrics
Member in the Duke Clinical Research Institute
·
2024 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Metabolic and Pharmacokinetic Profiling of a Ketone Ester by Background SGLT2 Inhibitor Therapy in HFrEF.
Journal Article JACC Basic Transl Sci · March 2025 Growing evidence supports therapeutic ketosis in heart failure with reduced ejection fraction, though uncertainty exists regarding use with SGLT2i and dose-dependent effects. In a phase I trial of 2 ketone ester (KE) doses in 20 heart failure with reduced ... Full text Link to item CitePopulation Pharmacokinetics of Caffeine in Infants with Hypoxic-Ischemic Encephalopathy: A Phase I, Dose-Escalating Trial.
Journal Article J Clin Pharmacol · February 12, 2025 The mainstay of treatment for infants with hypoxic-ischemic encephalopathy (HIE) is cooling. Caffeine may be an important adjunct to cooling and provide neuroprotection via its anti-inflammatory and anti-oxidative properties. This study aimed to characteri ... Full text Link to item CiteUrine biomarkers, acute kidney injury, and fluid overload in neonatal cardiac surgery.
Conference Cardiol Young · February 6, 2025 BACKGROUND: Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus, there is a need to ... Full text Link to item CiteRecent Grants
Real-world Data Enables Pharmacokinetic/Pharmacodynamic Drug Dosing in Critically Ill Children
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2029CPCCRN
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2026Pharmacokinetics and Pharmacodynamics of Digoxin in Infants with Single Ventricle Heart Disease
ResearchPrincipal Investigator · Awarded by DCRI-Duke-Site · 2024 - 2026View All Grants
Education, Training & Certifications
Georgetown University, School of Medicine ·
2016
M.D.