Current Appointments & Affiliations
Assistant Professor of Pediatrics
·
2024 - Present
Pediatrics, Critical Care Medicine,
Pediatrics
Member in the Duke Clinical Research Institute
·
2024 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Population Pharmacokinetics of Caffeine in Infants with Hypoxic-Ischemic Encephalopathy: A Phase I, Dose-Escalating Trial.
Journal Article J Clin Pharmacol · February 12, 2025 The mainstay of treatment for infants with hypoxic-ischemic encephalopathy (HIE) is cooling. Caffeine may be an important adjunct to cooling and provide neuroprotection via its anti-inflammatory and anti-oxidative properties. This study aimed to characteri ... Full text Link to item CiteUrine biomarkers, acute kidney injury, and fluid overload in neonatal cardiac surgery.
Conference Cardiol Young · February 6, 2025 BACKGROUND: Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus, there is a need to ... Full text Link to item CitePhysiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.
Journal Article CPT Pharmacometrics Syst Pharmacol · August 2024 Pantoprazole is a proton pump inhibitor indicated for the treatment of gastroesophageal reflux disease, a condition that disproportionately affects children with obesity. Appropriately dosing pantoprazole in children with obesity requires understanding the ... Full text Link to item CiteRecent Grants
Real-world Data Enables Pharmacokinetic/Pharmacodynamic Drug Dosing in Critically Ill Children
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2029CPCCRN
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2026Pharmacokinetics and Pharmacodynamics of Digoxin in Infants with Single Ventricle Heart Disease
ResearchPrincipal Investigator · Awarded by DCRI-Duke-Site · 2024 - 2026View All Grants
Education, Training & Certifications
Georgetown University, School of Medicine ·
2016
M.D.