Current Appointments & Affiliations
Professor Emeritus of Biochemistry
·
2010 - Present
Biochemistry,
Basic Science Departments
Dean Emeritus of the Graduate School
·
2010 - Present
Graduate School
Recent Publications
Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products.
Journal Article Biochemistry · October 7, 1997 To further understand the six-electron reductions of sulfite and nitrite catalyzed by the Escherichia coli sulfite reductase hemoprotein (SiRHP), we have determined crystallographic structures of the enzyme in complex with the inhibitors phosphate, carbon ... Full text Link to item CiteStructures of the siroheme- and Fe4S4-containing active center of sulfite reductase in different states of oxidation: heme activation via reduction-gated exogenous ligand exchange.
Journal Article Biochemistry · October 7, 1997 The active center of the Escherichia coli sulfite reductase hemoprotein (SiRHP) is exquisitely designed to catalyze the six-electron reductions of sulfite to sulfide and nitrite to ammonia. Refined high-resolution crystallographic structures of oxidized, t ... Full text Link to item CiteCrystallographic studies of the multi-electron reductions catalyzed by the siroheme and iron-sulfur cluster-containing enzyme sulfite reductase
Conference Acta Crystallographica Section A Foundations of Crystallography · August 8, 1996 Full text CiteRecent Grants
Biological Oxidations In Mitochondria And Microsomes
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1988 - 1990Mechanism Of Multielectron Reductases
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1987 - 1989View All Grants
Education, Training & Certifications
Johns Hopkins University ·
1965
Ph.D.