Scholars@Duke
E. Lee Tyrey

E. Lee Tyrey

Professor Emeritus of Obstetrics and Gynecology
Obstetrics and Gynecology, Reproductive Sciences
ltyrey@duke.edu
Box 3244 Med Ctr, Durham, NC 27710
246 Sands Bldg, Durham, NC 27710

Overview

Research interests focus on neuroendocrine mechanisms that regulate reproductive function in the female. Using the rat model, stereotaxic brain stimulation, electrolytic lesioning, and microsurgical transection of neural pathways are used to study brain systems that regulate the secretion of gonadotropins and prolactin from the anterior pituitary. Radioimmunoassays are used to monitor serum hormone levels during or after experimental manipulation. Disturbances of pituitary function that are induced by reproductive toxicants are studied with the goal of determining sites and mechanisms that mediate the adverse effects. Current studies address the disruption of reproductive cycles and ovulation by triazine herbicides.

Current Appointments & Affiliations

Professor Emeritus of Obstetrics and Gynecology · 2006 - Present Obstetrics and Gynecology, Reproductive Sciences, Obstetrics and Gynecology

Recent Grants

Developmental Effects Of Dietary Soy Phytoestrogens

ResearchCo-Principal Investigator · Awarded by Environmental Protection Agency · 1997 - 2001

Cannabinoid Effects On Female Reproductive Function

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1987 - 1989

View All Grants

Education, Training & Certifications

University of Illinois · 1969 Ph.D.
University of Illinois · 1964 M.S.
University of Illinois · 1963 B.S.