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Madeline M Robertson

Assistant Professor in Psychiatry and Behavioral Sciences
Psychiatry, Child & Family Mental Health & Community Psychiatry
2608 Erwin Rd, Suite 300, Durham, NC 27705

Selected Publications


Greater alcohol intake predicts accelerated brain aging in humans, which mediates the relationship between alcohol intake and behavioral inflexibility

Journal Article Alcohol, Clinical and Experimental Research · March 2025 AbstractBackgroundHazardous use of alcohol is associated with cognitive‐behavioral impairments and accelerated aging. To date, however, accelerated brain aging has not been tested as a med ... Full text Cite

Alterations in fear learning as a mechanism linking childhood exposure to violence with PTSD symptoms: a longitudinal study

Journal Article Psychological Medicine · September 2024 AbstractBackgroundFear learning is a core component of conceptual models of how adverse experiences may influence psychopathology. Specifically, existing theo ... Full text Cite

Alterations in neural circuits underlying emotion regulation following child maltreatment: a mechanism underlying trauma-related psychopathology.

Journal Article Psychol Med · August 2021 BACKGROUND: Disruptions in neural circuits underlying emotion regulation (ER) may be a mechanism linking child maltreatment with psychopathology. We examined the associations of maltreatment with neural responses during passive viewing of negative emotiona ... Full text Link to item Cite

Inhibitory corticotropin-releasing factor neurons in the dorsomedial prefrontal cortex promote stress-resilient behavior in male rodents.

Journal Article J Neurophysiol · February 1, 2021 Adaptive behavior in response to adverse experiences facilitates faster recovery and less time spent engaging in maladaptive behaviors that contribute to psychopathology, including anxiety, depression, and posttraumatic stress disorder. Dysregulation of ac ... Full text Link to item Cite

Resting-state EEG Connectivity in Young Children with ADHD.

Journal Article J Clin Child Adolesc Psychol · 2021 Objective: Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent and impairing neurodevelopmental disorder. While early childhood is a crucial time for early intervention, it is characterized by instability of ADHD diagnosis. Neural correla ... Full text Link to item Cite

Chronic alcohol exposure during critical developmental periods differentially impacts persistence of deficits in cognitive flexibility and related circuitry.

Journal Article Int Rev Neurobiol · 2021 Cognitive flexibility in decision making depends on prefrontal cortical function and is used by individuals to adapt to environmental changes in circumstances. Cognitive flexibility can be measured in the laboratory using a variety of discrete, translation ... Full text Link to item Cite

EEG power spectral slope differs by ADHD status and stimulant medication exposure in early childhood.

Journal Article J Neurophysiol · December 1, 2019 Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by hyperactivity/impulsivity and inattentiveness. Efforts toward the development of a biologically based diagnostic test have identified differences in th ... Full text Link to item Cite

Consistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes.

Journal Article Brain Stimul · 2019 BACKGROUND: Electrical neuromodulation via implanted electrodes is used in treating numerous neurological disorders, yet our knowledge of how different brain regions respond to varying stimulation parameters is sparse. OBJECTIVE/HYPOTHESIS: We hypothesized ... Full text Link to item Cite

A neural mass model to predict electrical stimulation evoked responses in human and non-human primate brain.

Journal Article J Neural Eng · December 2018 OBJECTIVE: Deep brain stimulation (DBS) is a valuable tool for ameliorating drug resistant pathologies such as movement disorders and epilepsy. DBS is also being considered for complex neuro-psychiatric disorders, which are characterized by high variabilit ... Full text Link to item Cite