Scholars@Duke
Maggie Marie Stoecker

Maggie Marie Stoecker

Assistant Professor of Pathology
Pathology
maggie.stoecker@duke.edu
Dept of Pathology, Box 3712, Durham, NC 27710

Selected Publications

Correction to: Axin gene methylation status correlates with radiosensitivity of lung cancer cells.

Journal Article BMC Cancer · March 27, 2019 Following publication of the original article. ... Full text Link to item Cite

Rare breast metastasis from adenoid cystic carcinoma of the submandibular gland.

Journal Article BMJ Case Rep · August 1, 2018 Adenoid cystic carcinomas (ACCs) are rare malignant neoplasms of exocrine glands, most commonly found in salivary glands. This report describes a 67-year-old woman with metastatic ACC to the breast, only the third reported case of its kind. The salivary gl ... Full text Link to item Cite

Overexpression of CRKL correlates with poor prognosis and cell proliferation in non-small cell lung cancer.

Journal Article Mol Carcinog · November 2013 Crk-Like (CRKL) is an adapter protein that has crucial roles in multiple biological processes, including cell proliferation, adhesion, and migration. Amplification of CRKL gene was found in non-small cell lung cancer (NSCLC). However, the expression patter ... Full text Link to item Cite

Axin gene methylation status correlates with radiosensitivity of lung cancer cells.

Journal Article BMC Cancer · August 2, 2013 BACKGROUND: We previously reported that Axin1 (Axin) is down-regulated in many cases of lung cancer, and X-ray irradiation increased Axin expression and inhibited lung cancer cells. The mechanisms, however, were not clear. METHODS: Four lung cancer cell li ... Full text Link to item Cite

Histiocytic/dendritic cell transformation of B-cell neoplasms: pathologic evidence of lineage conversion in differentiated hematolymphoid malignancies.

Journal Article Arch Pathol Lab Med · June 2013 B-cell lymphomas, such as low-grade follicular lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma, can transform to histiocytic/dendritic cell sarcoma (H/DS) in rare cases. The diagnosis of this unconventional neoplastic evolution relies ... Full text Link to item Cite

Sudden death due to undiagnosed T lymphoblastic leukemia/lymphoma in a 5-year-old boy.

Journal Article Am J Forensic Med Pathol · December 2012 Undiagnosed neoplasms in childhood are rare causes of sudden and unexpected death. Deaths due to undiagnosed hematologic malignancies are limited to a small number of case reports. The following case of acute leukemia was diagnosed at forensic autopsy in a ... Full text Link to item Cite

Follicular lymphoma with prominent Dutcher body formation: a pathologic study of 3 cases in comparison with nodal or splenic lymphoplasmacytic lymphoma and marginal zone lymphoma.

Journal Article Hum Pathol · November 2012 Dutcher bodies have been described in lymphoid neoplasms with plasmacytic differentiation, including plasma cell myeloma, lymphoplasmacytic lymphoma, and marginal zone lymphoma. We report a pathologic study of 3 cases of follicular lymphoma with extensive ... Full text Link to item Cite

Expression of ezrin correlates with malignant phenotype of lung cancer, and in vitro knockdown of ezrin reverses the aggressive biological behavior of lung cancer cells.

Journal Article Tumour Biol · October 2012 Ezrin, one of the ezrin-radixin-moesin proteins, is involved in the formation of cell membrane processes such as lamellipodia and filopodia and acts as a membrane-cytoskeleton linker. Its aberrant expression correlates with development and progression of s ... Full text Link to item Cite

Systemic mastocytosis with associated clonal hematologic nonmast cell lineage disease: a clinicopathologic review.

Journal Article Arch Pathol Lab Med · July 2012 Systemic mastocytosis (SM) is a heterogeneous disease with 6 subtypes, including systemic mastocytosis with associated clonal hematologic nonmast cell lineage disease (SM-AHNMD). Bone marrow biopsy specimens show multifocal aggregates of mast cells with pr ... Full text Link to item Cite

Concomitant Waldenstrom macroglobulinemia and IgA plasmablastic myeloma in a patient with untreated IgM paraproteinemia: sequential development of biclonal B-cell neoplasms over a 10-year period in a single individual.

Journal Article Hum Pathol · July 2012 Waldenstrom macroglobulinemia and plasma cell myeloma are both mature B-cell neoplasms primarily involving bone marrow and frequently demonstrating paraproteinemia. Plasma cell myeloma has been described in association with other indolent B-cell lymphomas, ... Full text Link to item Cite

Molecular detection of circulating Sezary cells in patients with mycosis fungoides: could it predict future development of secondary Sezary syndrome? A single-institution experience.

Journal Article Leuk Lymphoma · May 2012 While the majority of patients with early-stage mycosis fungoides (MF) have an excellent prognosis, a few cases progress to secondary Sezary syndrome (sSS), which carries a dismal clinical outcome. We retrospectively analyzed 135 cases of MF/SS and correla ... Full text Link to item Cite

N-terminal 1-54 amino acid sequence and Armadillo repeat domain are indispensable for P120-catenin isoform 1A in regulating E-cadherin.

Journal Article PLoS One · 2012 P120-catenin (p120ctn) exerts important roles in regulating E-cadherin and invasiveness in cancer cells. However, the mechanisms by which p120ctn isoforms 1 and 3 modulate E-cadherin expression are poorly understood. In the current study, HBE, H460, SPC an ... Full text Link to item Cite

P120-catenin isoforms 1 and 3 regulate proliferation and cell cycle of lung cancer cells via β-catenin and Kaiso respectively.

Journal Article PLoS One · 2012 BACKGROUND: The different mechanisms involved in p120-catenin (p120ctn) isoforms' 1/3 regulation of cell cycle progression are still not elucidated to date. METHODS AND FINDINGS: We found that both cyclin D1 and cyclin E could be effectively restored by re ... Full text Link to item Cite

A small cell variant of ALK-positive, CD8-positive anaplastic large cell lymphoma with primary subcutaneous presentation mimicking subcutaneous panniculitis-like T-cell lymphoma.

Journal Article Pathol Res Pract · August 15, 2011 ALK-positive anaplastic large cell lymphoma (ALK+ ALCL) is an uncommon non-Hodgkin's lymphoma of T-cell origin, the majority of which express CD4 and show frequent pan-T-cell antigen loss. While most cases of ALK+ ALCL have the common pattern characterized ... Full text Link to item Cite

Chronic Progressive External Ophthalmoplegia: A Report of 2 Cases.

Conference LABORATORY INVESTIGATION · February 1, 2011 Link to item Cite

Recurrent granulosa cell tumor presenting with spontaneous retroperitoneal hemorrhage: A case report.

Journal Article Gynecol Oncol Case Rep · 2011 ► Patients diagnosed with granulosa cell tumor require long-term surveillance. ► Recurrent granulosa cell tumor may present as spontaneous retroperitoneal hemorrhage. ► We present an unusual case of recurrent granulosa cell tumor resulting in retroperitone ... Full text Link to item Cite

Primary cutaneous giant cell plasmacytoma in an organ transplant recipient: a rare presentation of a posttransplant lymphoproliferative disorder.

Journal Article Am J Dermatopathol · July 2010 Posttransplant lymphoproliferative disorder (PTLD) is comprised of a spectrum of lymphoid diseases, ranging from early lesions, such as plasmacytic hyperplasia, to monomorphic neoplasms, including plasmacytoma-like lesions. Although PTLD may involve a vari ... Full text Link to item Cite

Primary mediastinal (thymic) large B cell lymphoma with aberrant expression of CD3: a case report with review of the literature.

Journal Article Int J Hematol · April 2010 We report the first case of primary mediastinal large B cell lymphoma (PMBL) with aberrant expression of CD3. PMBL is a subtype of diffuse large B cell lymphoma (DLBCL) and usually presents with bulky mediastinal lesions. Lineage ambiguity/infidelity is un ... Full text Link to item Cite