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Malcolm R DeBaun

Assistant Professor of Orthopaedic Surgery
Orthopaedic Surgery
Box 104002, DUMC, Durham, NC 27710
311 Trent Drive, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor of Orthopaedic Surgery · 2021 - Present Orthopaedic Surgery, Clinical Science Departments

Recent Publications


A controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafil.

Journal Article Blood · June 26, 2025 Recurrent ischemic priapism is a common complication of sickle cell anemia (SCA) and is associated with devastating physical and psychosocial consequences. All previous trials for priapism prevention have failed to demonstrate clear efficacy. We conducted ... Full text Link to item Cite

Reducing Time to Analgesia for Sickle Cell Pain Episode Treatment in the Pediatric Emergency Department

Journal Article Pediatric Quality and Safety · June 4, 2025 Introduction: Pain episodes are the most common emergency department (ED) presentation for patients with sickle cell disease (SCD). Prompt pain medication and frequent pain assessments are recommended. Our SMART aim was to reduce the time from ED rooming t ... Full text Cite
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Recent Grants


Safety and Efficacy of XPERIENCE Irrigation Solution to Prevent Fracture Related Infection: a Preclinical Study

ResearchPrincipal Investigator · Awarded by Next Science · 2024 - 2026

Fresh Tissue Lab

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by CurvaFix, Inc. · 2022 - 2023

Fresh Tissue Lab

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Medical Device Business Services, Inc. · 2022 - 2022

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Education, Training & Certifications


Stanford University, School of Medicine · 2015 M.D.