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Marcia David Palma

Research Associate, Senior
Molecular Genetics and Microbiology

Research Interests


Marcia David-Palma holds a degree in Biochemistry, a Master’s in Applied Microbiology, and a PhD in Biology with a specialization in Molecular Genetics from the Universidade Nova de Lisboa, Portugal. Her doctoral research provided key insights into the life cycle of the carotenoid-producing basidiomycete Phaffia rhodozyma.
Currently a Senior Research Associate at Duke University, Dr. David-Palma investigates the molecular characterization and evolutionary dynamics of reproductive systems in basidiomycete fungi, with a focus on species from the genera Cryptococcus, Kwoniella, and Malassezia. Her research also explores molecular pathways involved in the development of fungal pathogenicity in humans, as well as the ecological and evolutionary processes driving fungal biodiversity.

Selected Grants


Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis

ResearchSenior Research Associate · Awarded by National Institute of Allergy and Infectious Diseases · 1997 - 2026

Malassezia and Candida auris: skin microbiome dysbiosis and de-regulation of cutaneous homeostasis

ResearchResearch Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2026

Structure, function, and evolution of the Cryptococcus MAT locus

ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2002 - 2025

Fellowships, Gifts, and Supported Research


Cryptococcus in Africa: exploring diversity, host associations, and evolution of pathogenicity · February 1, 2025 - December 31, 2026 Awarded by: CIFAR Catalyst Fund
Comparative genomic analysis reveals karyotype evolution resulting in giant fungal chromosomes · December 2022 - June 2024 Awarded by: CIFAR Catalyst Fund