Overview
Marcy Uyenoyama studies mechanisms of evolutionary change at the molecular and population levels. Among the questions under study include the prediction and detection of the effects of natural selection on genomic structure. A major area of research addresses the development of maximum-likelihood and Bayesian methods for inferring evolutionary processes from the pattern of molecular variation. Evolutionary processes currently under study include characterization of population structure across genomes.
Current Appointments & Affiliations
Professor of Biology
·
2000 - Present
Biology,
Trinity College of Arts & Sciences
Recent Publications
Neutral Genetic Diversity in Mixed Mating Systems.
Journal Article Genes · December 2024 Background/objectivesSystems of reproduction differ with respect to the magnitude of neutral genetic diversity maintained in a population. In particular, the partitioning of reproductive organisms into mating types and regular inbreeding have long ... Full text Open Access CiteJoint identity among loci under mutation and regular inbreeding.
Journal Article Theoretical population biology · October 2024 This study describes a compact method for determining joint probabilities of identity-by-state (IBS) within and between loci in populations evolving under genetic drift, crossing-over, mutation, and regular inbreeding (partial self-fertilization). Analogue ... Full text CiteWright's Hierarchical F-Statistics.
Journal Article Molecular biology and evolution · May 2024 This perspective article offers a meditation on FST and other quantities developed by Sewall Wright to describe the population structure, defined as any departure from reproduction through random union of gametes. Concepts related to the F-statistics draw ... Full text Open Access CiteRecent Grants
Bioinformatics and Computational Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2021Mathematical Population Genetics
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1986 - 2014Mathematical Population Genetics
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1996 - 2005View All Grants
Education, Training & Certifications
Stanford University ·
1978
Ph.D.
Stanford University ·
1974
B.S.