Overview
PhD candidate in Dennis Ko's lab | Joined MGM program in 2020 | Washington University in St. Louis '19
Studying mechanism and pathophysiology of Salmonella secreted protein effectors.
Studying mechanism and pathophysiology of Salmonella secreted protein effectors.
Current Appointments & Affiliations
Recent Publications
A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory gene expression.
Journal Article Cell Rep · April 22, 2025 Salmonella causes ∼1 million cases of gastroenteritis annually in the United States. Critical to virulence are secreted effectors that reprogram host functions. We previously discovered the effector SarA facilitates phosphorylation of STAT3, inducing expre ... Full text Link to item CiteNuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages.
Journal Article mBio · April 10, 2024 UNLABELLED: Salmonella serovars Typhi and Paratyphi cause a prolonged illness known as enteric fever, whereas other serovars cause acute gastroenteritis. Mechanisms responsible for the divergent clinical manifestations of nontyphoidal and enteric fever Sal ... Full text Link to item CiteRecent Grants
The Molecular Mechanism and Pathophysiology of Robust STAT3 Signaling During Oral Salmonella Typhimurium Infection
FellowshipPI-Fellow · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2027View All Grants