Mary Louise Markert | Scholars@Duke

Mary Louise Markert
Professor Emeritus of Pediatrics

Dr. Markert is currently investigating cultured thymus tissue implantatoin in children with congenital athymia. Congenital athymia is a fatal disease as the patients have no T cells to defend against infection. There are several etiologies of congenital athymia including 22q11.2 deletion syndrome, CHARGE (coloboma, heart defects, choanal atresia, growth or mental retardation, genital abnormalities and ear anomalies and or deafness. Complete DiGeorge anomaly is a designation that encompasses the above in addition with patients with athymia who have heart and/or parathyroid defects. In research studies, patients with athymia who have no T cells are given postnatal cultured thymus tissue implants (CTTI). Of 95 patients with congenital athymia approximately 72% have developed T cells and survive. Dr. Markert is now studying patients previously given CTTI to learn how long the tissue functions and why the T cell numbers in her post thymus transplantation patients remain low for age - similar to the T cell numbers in patients with partial DiGeorge anomaly who do not need CTTI. In 2012, Dr. Markert began studies in an animal model to use CTTI to induce tolerance to solid organ transplants. This work in rats has been published and showed tolerance induction for solid organ transplants.

Current Appointments & Affiliations

Professor Emeritus of Pediatrics, Pediatrics, Allergy and Immunology, Pediatrics 2021
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1982

Contact Information

Box 3068 Med Ctr, Durham, NC 27710
Rm 101 Research Park 4, Research Dr., Durham, NC 27710
marke001@mc.duke.edu (919) 684-6263

Background
Education, Training, & Certifications
- M.D., Duke University 1982
- Ph.D., Duke University 1981
Previous Appointments & Affiliations
- Professor of Immunology, Integrative Immunobiology, Basic Science Departments 2013 - 2022
- Professor of Pediatrics, Pediatrics, Allergy and Immunology, Pediatrics 2011 - 2021
- Associate Professor of Immunology, Integrative Immunobiology, Basic Science Departments 2004 - 2013
- Associate Professor of Pediatrics, Pediatrics, Allergy and Immunology, Pediatrics 1997 - 2011
- Director, Clinical Research Unit, School of Medicine, Duke University 1993 - 2005
- Assistant Professor of Immunology, Integrative Immunobiology, Basic Science Departments 1994 - 2004
- Assistant Professor of Pediatrics, Pediatrics, Allergy and Immunology, Pediatrics 1987 - 1997
- Assistant Professor of Immunology, Molecular Genetics and Microbiology, Basic Science Departments 1991 - 1992
Recognition
In the News
- APR 15, 2022
  
  Pioneering Therapy Gives New Hope to Babies Lacking Thymus
- MAR 7, 2022
  
  Baby Receives World’s First Combination Heart Transplant-Thymus Procedure
- OCT 11, 2021 Duke Health News
  
  After Decades of Research, Drug Developed at Duke Receives FDA Approval
- AUG 4, 2021 Duke Health News
  
  Pioneering Therapy Provides Long-Term Survival for Babies Lacking Thymus
Expertise
Subject Headings
Research
Selected Grants
- Transplantation of Cryopreserved Thymus awarded by National Institutes of Health 2023 - 2025
- Enzyvant Monkey Study awarded by Enzyvant 2019 - 2022
- Thymus Transplantation in Pediatric Patients awarded by Orphavant Sciences GmbH 2017 - 2020
- Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
- Thymus transplantation to induce tolerance to heart transplants awarded by Enzyvant Sciences Ltd. 2017 - 2018
- Training Program in Inflammatory and Immunological Diseases awarded by National Institutes of Health 1980 - 2017
- Thymic Transplantation in Complete DiGeorge Syndrome awarded by National Institutes of Health 2004 - 2016
- Clinical Oncology Research Career Development Program awarded by National Institutes of Health 2009 - 2015
- Phase I Serum-free cultured thymus transplantation in DiGeorge anomaly, IND9836, Feb 5, 2008 awarded by National Institutes of Health 2009 - 2011
- Thymic Transplantation in Complete DiGeorge Syndrome awarded by National Institutes of Health 2009 - 2010
- Dynamics of TCR Repertoire Following Thymus Transplant awarded by National Institutes of Health 2004 - 2009
- NIH National Research Service Award Institutional Research Training Grant (T32) Duke Pediatric Cardiology awarded by National Institutes of Health 2004 - 2009
- Dose Study of Thymus Transplantation, IND 9836 awarded by Food and Drug Administration 2005 - 2008
- Parathyroid and Thymus Transplants in DiGeorge Syndrome awarded by National Institutes of Health 2004 - 2006
- Telomerase RNA Transfected Dendritic Cell Vaccines awarded by National Institutes of Health 2002 - 2006
- Thymus Transplantation in Complete DiGeorge Syndrom awarded by National Institutes of Health 1999 - 2004
- Thymic Transplantation in Complete DiGeorge Syndrome awarded by National Institutes of Health 1999 - 2004
- General Clinical Research Center awarded by National Institutes of Health 1975 - 2003
- Same awarded by National Institutes of Health 1995 - 2000
- Viral Control And Immune Reconstitution In Hiv Infection awarded by National Institutes of Health 1996 - 1999
- Viral Control & Immune Reconstitution In Hiv Infection awarded by National Institutes of Health 1995 - 1999
- Mechanisms And Therapy Of Primary Immunodeficiency awarded by National Institutes of Health 1996 - 1999
- Mechanisms And Therapy Of Primary Immunodeficiency awarded by National Institutes of Health 1995 - 1999
- Mechanisms and therapy of primary immunodeficiency awarded by National Institutes of Health 1995 - 1999
- Research Training In Allergy And Clinical Immunology awarded by National Institutes of Health 1907 - 1999
- General Clinical Research Center (Cru) awarded by National Institutes of Health 1975 - 1998
- Center For Developmental Immunology And Host Defense awarded by National Institutes of Health 1996 - 1998
- Center For Developmental Immunology And Host Defense awarded by National Institutes of Health 1992 - 1997
- General Clinical Research Center awarded by National Institutes of Health 1993 - 1995
- The Thymus In Immune Reconstitution For Hiv Infection awarded by National Institutes of Health 1994 - 1995
- Ada Regulation And The Immune Response: Animal Models awarded by National Institutes of Health 1994 - 1995
- Ada Regulation And The Immune Response: Animal Models awarded by National Institutes of Health 1992 - 1995
- Immunodeficiency And Ada Deficiency -- Molecular Analysis awarded by National Institutes of Health 1990 - 1991
- Immunodeficiency And Ada Deficiency - Molecular Analysis awarded by National Institutes of Health 1988 - 1991
- Immunodeficiency And Ada Deficiency: Molecular Analysis awarded by National Institutes of Health 1986 - 1989
External Relationships
- Enzyvant Therapeutics GmbH
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Kang, Lillian, M Louise Markert, and Joseph W. Turek. “Induction of donor-specific tolerance to heart transplantation: From concept to clinical translation.” J Thorac Cardiovasc Surg 165, no. 5 (May 2023): 1661–66. https://doi.org/10.1016/j.jtcvs.2021.12.048.
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  - Mustillo, Peter J., Kathleen E. Sullivan, Ivan K. Chinn, Luigi D. Notarangelo, Elie Haddad, E Graham Davies, Maria Teresa de la Morena, et al. “Clinical Practice Guidelines for the Immunological Management of Chromosome 22q11.2 Deletion Syndrome and Other Defects in Thymic Development.” J Clin Immunol 43, no. 2 (February 2023): 247–70. https://doi.org/10.1007/s10875-022-01418-y.
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  - Hicks, Elizabeth Daly, Noah O. Agada, Tyler R. Yates, Matthew S. Kelly, Jonathan S. Tam, Ronald M. Ferdman, Louis R. Dibernardo, John F. Madden, M Anthony Moody, and Mary Louise Markert. “Case Report: Nontuberculous mycobacterial infections in children with complete DiGeorge anomaly.” Front Immunol 14 (2023): 1078976. https://doi.org/10.3389/fimmu.2023.1078976.
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  - Bhalla, Pratibha, Qiumei Du, Ashwani Kumar, Chao Xing, Angela Moses, Igor Dozmorov, Christian A. Wysocki, et al. “Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome.” J Clin Invest 132, no. 22 (November 15, 2022). https://doi.org/10.1172/JCI160101.
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  - Fitch, Zachary W., Lillian Kang, Jie Li, Stuart J. Knechtle, Joseph W. Turek, Allan D. Kirk, M Louise Markert, and Jean Kwun. “Introducing thymus for promoting transplantation tolerance.” J Allergy Clin Immunol 150, no. 3 (September 2022): 549–56. https://doi.org/10.1016/j.jaci.2022.05.006.
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  - Markert, M Louise, Stephanie E. Gupton, and Elizabeth A. McCarthy. “Experience with cultured thymus tissue in 105 children.” J Allergy Clin Immunol 149, no. 2 (February 2022): 747–57. https://doi.org/10.1016/j.jaci.2021.06.028.
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  - Gupton, Stephanie E., Elizabeth A. McCarthy, and M Louise Markert. “Care of Children with DiGeorge Before and After Cultured Thymus Tissue Implantation.” J Clin Immunol 41, no. 5 (July 2021): 896–905. https://doi.org/10.1007/s10875-021-01044-0.
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  - Bosticardo, Marita, Francesca Pala, Enrica Calzoni, Ottavia M. Delmonte, Kerry Dobbs, Cameron L. Gardner, Nicolo’ Sacchetti, et al. “Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia.” Blood Adv 4, no. 12 (June 23, 2020): 2611–16. https://doi.org/10.1182/bloodadvances.2020001730.
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  - Bifsha, Panojot, Jennifer W. Leiding, Sung-Yun Pai, Aurelien B. L. Colamartino, Nicholas Hartog, Joseph A. Church, Benjamin R. Oshrine, Jennifer M. Puck, M Louise Markert, and Elie Haddad. “Diagnostic assay to assist clinical decisions for unclassified severe combined immune deficiency.” Blood Adv 4, no. 12 (June 23, 2020): 2606–10. https://doi.org/10.1182/bloodadvances.2020001736.
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  - Kwun, Jean, Jie Li, Clay Rouse, Jae Berm Park, Alton B. Farris, Maragatha Kuchibhatla, Joseph W. Turek, Stuart J. Knechtle, Allan D. Kirk, and M Louise Markert. “Cultured thymus tissue implantation promotes donor-specific tolerance to allogeneic heart transplants.” Jci Insight 5, no. 11 (June 4, 2020). https://doi.org/10.1172/jci.insight.129983.
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  - Hale, Laura P., Jadee Neff, Lynn Cheatham, Diana Cardona, M Louise Markert, and Joanne Kurtzberg. “Histopathologic assessment of cultured human thymus.” Plos One 15, no. 3 (2020): e0230668. https://doi.org/10.1371/journal.pone.0230668.
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  - Du, Qiumei, Larry K. Huynh, Fatma Coskun, Erika Molina, Matthew A. King, Prithvi Raj, Shaheen Khan, et al. “FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans.” J Clin Invest 129, no. 11 (November 1, 2019): 4724–38. https://doi.org/10.1172/JCI127565.
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  - Amatuni, George S., Robert J. Currier, Joseph A. Church, Tracey Bishop, Elena Grimbacher, Alan Anh-Chuong Nguyen, Rajni Agarwal-Hashmi, et al. “Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017.” Pediatrics 143, no. 2 (February 2019). https://doi.org/10.1542/peds.2018-2300.
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  - Liu, Ning, Kelly Schoch, Xi Luo, Loren D. M. Pena, Venkata Hemanjani Bhavana, Mary K. Kukolich, Sarah Stringer, et al. “Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder.” Hum Mol Genet 27, no. 14 (July 15, 2018): 2454–65. https://doi.org/10.1093/hmg/ddy146.
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  - Davies, E Graham, Melissa Cheung, Kimberly Gilmour, Jesmeen Maimaris, Joe Curry, Anna Furmanski, Neil Sebire, et al. “Thymus transplantation for complete DiGeorge syndrome: European experience.” J Allergy Clin Immunol 140, no. 6 (December 2017): 1660-1670.e16. https://doi.org/10.1016/j.jaci.2017.03.020.
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  - Stone, Cosby A., Mary Louise Markert, Roshini S. Abraham, and Allison Norton. “A case of atypical, complete DiGeorge syndrome without 22q11 mutation.” Ann Allergy Asthma Immunol 118, no. 5 (May 2017): 640-642.e2. https://doi.org/10.1016/j.anai.2017.02.025.
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  - Yin, Suellen Moli, Ronald M. Ferdman, Larry Wang, M Louise Markert, and Jonathan S. Tam. “Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome.” J Clin Immunol 35, no. 5 (July 2015): 435–38. https://doi.org/10.1007/s10875-015-0171-3.
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  - Rendell, Victoria R., Charles Giamberardino, Jie Li, M Louise Markert, and Todd V. Brennan. “Complete thymectomy in adult rats with non-invasive endotracheal intubation.” J Vis Exp, no. 94 (December 29, 2014). https://doi.org/10.3791/52152.
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  - Lee, Jan Hau, M Louise Markert, Christoph P. Hornik, Elizabeth A. McCarthy, Stephanie E. Gupton, Ira M. Cheifetz, and David A. Turner. “Clinical course and outcome predictors of critically ill infants with complete DiGeorge anomaly following thymus transplantation.” Pediatr Crit Care Med 15, no. 7 (September 2014): e321–26. https://doi.org/10.1097/PCC.0000000000000219.
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  - Louise Markert, M. “Thymus Transplantation,” August 12, 2014, 1059–67. https://doi.org/10.1016/B978-0-12-405546-9.00060-1.
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  - Yu, Xiaomin, Jorge R. Almeida, Sam Darko, Mirjam van der Burg, Suk See DeRavin, Harry Malech, Andrew Gennery, et al. “Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development.” J Allergy Clin Immunol 133, no. 4 (April 2014): 1109–15. https://doi.org/10.1016/j.jaci.2013.11.018.
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  - Ciupe, Stanca M., Blythe H. Devlin, Mary Louise Markert, and Thomas B. Kepler. “Quantification of total T-cell receptor diversity by flow cytometry and spectratyping.” Bmc Immunol 14 (August 6, 2013): 35. https://doi.org/10.1186/1471-2172-14-35.
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  - Markert, M Louise, Stephanie E. Gupton, Elizabeth A. McCarthy, Blythe H. Devlin, Chia-san Hsieh, Jie Li, Troy R. Torgerson, Hans D. Ochs, and Rebecca H. Buckley. “RESPONSE TO BACTERIOPHAGE Phi chi 174 IN CHILDREN WITH PARTIAL DIGEORGE ANOMALY AND IN CHILDREN WITH COMPLETE DIGEORGE ANOMALY AFTER CULTURED POSTNATAL ALLOGENEIC THYMUS TRANSPLANTATION.” Journal of Clinical Immunology 33, no. 3 (April 1, 2013): 679–80.
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  - McCarthy, Elizabeth A., Chia-san Hsieh, Jie Li, Stephanie E. Gupton, Blythe H. Devlin, Alain Fischer, Despina Moshous, and M Louise Markert. “THYMUS TRANSPLANTATION IN A THREE YEAR OLD CHILD WHO DID NOT DEVELOP SUFFICIENT NAIVE CD4 T CELLS AFTER PARENTAL BONE MARROW STEM CELL TRANSPLANTATION.” Journal of Clinical Immunology 33, no. 3 (April 1, 2013): 676–676.
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  - Heimall, Jennifer, Michael Keller, Rushani Saltzman, Nancy Bunin, Donna McDonald-McGinn, Elaine Zakai, Jean-Pierre de Villartay, et al. “Diagnosis of 22q11.2 deletion syndrome and artemis deficiency in two children with T-B-NK+ immunodeficiency.” J Clin Immunol 32, no. 5 (October 2012): 1141–44. https://doi.org/10.1007/s10875-012-9741-9.
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  - Albuquerque, Adriana S., José G. Marques, Susana L. Silva, Dario Ligeiro, Blythe H. Devlin, Jacques Dutrieux, Rémi Cheynier, et al. “Human FOXN1-deficiency is associated with αβ double-negative and FoxP3+ T-cell expansions that are distinctly modulated upon thymic transplantation.” Plos One 7, no. 5 (2012): e37042. https://doi.org/10.1371/journal.pone.0037042.
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  - Knutsen, Alan P., Mei W. Baker, and M Louise Markert. “Interpreting low T-cell receptor excision circles in newborns with DiGeorge anomaly: importance of assessing naive T-cell markers.” J Allergy Clin Immunol 128, no. 6 (December 2011): 1375–76. https://doi.org/10.1016/j.jaci.2011.08.019.
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  - Li, Bin, Jie Li, Blythe H. Devlin, and M Louise Markert. “Thymic microenvironment reconstitution after postnatal human thymus transplantation.” Clin Immunol 140, no. 3 (September 2011): 244–59. https://doi.org/10.1016/j.clim.2011.04.004.
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  - Hornik, Christoph P., Mary E. Hartman, M Louise Markert, Andrew J. Lodge, Ira M. Cheifetz, and David A. Turner. “Successful extracorporeal membrane oxygenation for respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation.” Respir Care 56, no. 6 (June 2011): 866–70. https://doi.org/10.4187/respcare.01051.
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  - Chinn, Ivan K., and M Louise Markert. “Induction of tolerance to parental parathyroid grafts using allogeneic thymus tissue in patients with DiGeorge anomaly.” J Allergy Clin Immunol 127, no. 6 (June 2011): 1351–55. https://doi.org/10.1016/j.jaci.2011.03.033.
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  - Markert, M Louise, José G. Marques, Bénédicte Neven, Blythe H. Devlin, Elizabeth A. McCarthy, Ivan K. Chinn, Adriana S. Albuquerque, et al. “First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases.” Blood 117, no. 2 (January 13, 2011): 688–96. https://doi.org/10.1182/blood-2010-06-292490.
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  - Chinn, Ivan K., John A. Olson, Michael A. Skinner, Elizabeth A. McCarthy, Stephanie E. Gupton, Dong-Feng Chen, Francisco A. Bonilla, et al. “Mechanisms of tolerance to parental parathyroid tissue when combined with human allogeneic thymus transplantation.” J Allergy Clin Immunol 126, no. 4 (October 2010): 814-820.e8. https://doi.org/10.1016/j.jaci.2010.07.016.
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  - Markert, M Louise, Blythe H. Devlin, and Elizabeth A. McCarthy. “Thymus transplantation.” Clin Immunol 135, no. 2 (May 2010): 236–46. https://doi.org/10.1016/j.clim.2010.02.007.
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  - Renner, Ellen D., Dominik Hartl, Stacey Rylaarsdam, Marguerite L. Young, Linda Monaco-Shawver, Gary Kleiner, M Louise Markert, et al. “Comèl-Netherton syndrome defined as primary immunodeficiency.” J Allergy Clin Immunol 124, no. 3 (September 2009): 536–43. https://doi.org/10.1016/j.jaci.2009.06.009.
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  - Ciupe, Stanca M., Blythe H. Devlin, M Louise Markert, and Thomas B. Kepler. “The dynamics of T-cell receptor repertoire diversity following thymus transplantation for DiGeorge anomaly.” Plos Comput Biol 5, no. 6 (June 2009): e1000396. https://doi.org/10.1371/journal.pcbi.1000396.
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  - Li, Bin, Jie Li, Chia-San Hsieh, Laura P. Hale, Yi-Ju Li, Blythe H. Devlin, and M Louise Markert. “Characterization of cultured thymus tissue used for transplantation with emphasis on promiscuous expression of thyroid tissue-specific genes.” Immunol Res 44, no. 1–3 (2009): 71–83. https://doi.org/10.1007/s12026-008-8083-4.
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  - Markert, M Louise, Blythe H. Devlin, Ivan K. Chinn, and Elizabeth A. McCarthy. “Thymus transplantation in complete DiGeorge anomaly.” Immunol Res 44, no. 1–3 (2009): 61–70. https://doi.org/10.1007/s12026-008-8082-5.
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  - Markert, M. L., B. H. Devlin, E. A. McCarthy, I. K. Chinn, and L. P. Hale. “Thymus transplantation,” December 1, 2008, 255–67. https://doi.org/10.1007/978-88-470-0828-1_30.
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  - Markert, M. L., and B. H. Devlin. “Thymic reconstitution,” December 1, 2008, 1253–61. https://doi.org/10.1016/B978-0-323-04404-2.10084-3.
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  - Albuquerque, A. S., J. G. Marques, S. L. Silva, I. K. Chinn, B. H. Devlin, R. Cheynier, C. Pignata, R. M. Victorino, M. L. Markert, and A. E. Sousa. “Immunological reconstitution following thymic transplantation of a nude/SCID patient.” Clinical and Experimental Immunology 154 (November 1, 2008): 36–36.
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  - Markert, M. L., B. H. Devlin, I. K. Chinn, E. A. McCarthy, and Y. J. Li. “Factors affecting success of thymus transplantation for complete DiGeorge anomaly.” Am J Transplant 8, no. 8 (August 2008): 1729–36. https://doi.org/10.1111/j.1600-6143.2008.02301.x.
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  - Markert, M Louise, Jie Li, Blythe H. Devlin, Jeffrey C. Hoehner, Henry E. Rice, Michael A. Skinner, Yi-Ju Li, and Laura P. Hale. “Use of allograft biopsies to assess thymopoiesis after thymus transplantation.” J Immunol 180, no. 9 (May 1, 2008): 6354–64. https://doi.org/10.4049/jimmunol.180.9.6354.
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  - Selim, Maria Angelica, Mary L. Markert, James L. Burchette, Christopher M. Herman, and John W. Turner. “The cutaneous manifestations of atypical complete DiGeorge syndrome: a histopathologic and immunohistochemical study.” J Cutan Pathol 35, no. 4 (April 2008): 380–85. https://doi.org/10.1111/j.1600-0560.2007.00816.x.
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  - Markert, M Louise. “Treatment of infants with complete DiGeorge anomaly.” J Allergy Clin Immunol 121, no. 4 (April 2008): 1063. https://doi.org/10.1016/j.jaci.2007.12.1181.
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  - Chinn, Ivan K., Blythe H. Devlin, Yi-Ju Li, and M Louise Markert. “Long-term tolerance to allogeneic thymus transplants in complete DiGeorge anomaly.” Clin Immunol 126, no. 3 (March 2008): 277–81. https://doi.org/10.1016/j.clim.2007.11.009.
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  - Hudson, Lori L., M. Louise Markert, Blythe H. Devlin, Barton F. Haynes, and Gregory D. Sempowski. “Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection.” Semin Immunol 19, no. 5 (October 2007): 297–309. https://doi.org/10.1016/j.smim.2007.10.002.
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  - Markert, M Louise, Blythe H. Devlin, Marilyn J. Alexieff, Jie Li, Elizabeth A. McCarthy, Stephanie E. Gupton, Ivan K. Chinn, et al. “Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants.” Blood 109, no. 10 (May 15, 2007): 4539–47. https://doi.org/10.1182/blood-2006-10-048652.
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  - Cunningham Rundles, Charlotte, Thomas Fleisher, Mary Louise Markert, Jordan Orange, Hans Ochs, and Kathleen Sullivan. “New developments in primary immunodeficiencies: Report on the 2006 CIS Primary Immunodeficiency Diseases Consortium Conference, June 1, 2006.” Clin Immunol 121, no. 3 (December 2006): 369–71. https://doi.org/10.1016/j.clim.2006.06.004.
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  - He, Min, John K. Tomfohr, Blythe H. Devlin, Marcella Sarzotti, M Louise Markert, and Thomas B. Kepler. “SpA: web-accessible spectratype analysis: data management, statistical analysis and visualization.” Bioinformatics 21, no. 18 (September 15, 2005): 3697–99. https://doi.org/10.1093/bioinformatics/bti600.
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  - Kepler, Thomas B., Min He, John K. Tomfohr, Blythe H. Devlin, Marcella Sarzotti, and M Louise Markert. “Statistical analysis of antigen receptor spectratype data.” Bioinformatics 21, no. 16 (August 15, 2005): 3394–3400. https://doi.org/10.1093/bioinformatics/bti539.
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  - Rice, Henry E., Michael A. Skinner, Samuel M. Mahaffey, Keith T. Oldham, Richard J. Ing, Laura P. Hale, and M Louise Markert. “Thymic transplantation for complete DiGeorge syndrome: medical and surgical considerations.” J Pediatr Surg 39, no. 11 (November 2004): 1607–15. https://doi.org/10.1016/j.jpedsurg.2004.07.020.
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  - Markert, M Louise, Marilyn J. Alexieff, Jie Li, Marcella Sarzotti, Daniel A. Ozaki, Blythe H. Devlin, Debra A. Sedlak, et al. “Postnatal thymus transplantation with immunosuppression as treatment for DiGeorge syndrome.” Blood 104, no. 8 (October 15, 2004): 2574–81. https://doi.org/10.1182/blood-2003-08-2984.
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  - Markert, M Louise, Marilyn J. Alexieff, Jie Li, Marcella Sarzotti, Daniel A. Ozaki, Blythe H. Devlin, Gregory D. Sempowski, et al. “Complete DiGeorge syndrome: development of rash, lymphadenopathy, and oligoclonal T cells in 5 cases.” J Allergy Clin Immunol 113, no. 4 (April 2004): 734–41. https://doi.org/10.1016/j.jaci.2004.01.766.
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  - Hale, Laura P., and M Louise Markert. “Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus.” J Immunol 172, no. 1 (January 1, 2004): 617–24. https://doi.org/10.4049/jimmunol.172.1.617.
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  - Markert, M Louise, Marcella Sarzotti, Daniel A. Ozaki, Gregory D. Sempowski, Maria E. Rhein, Laura P. Hale, Francoise Le Deist, et al. “Thymus transplantation in complete DiGeorge syndrome: immunologic and safety evaluations in 12 patients.” Blood 102, no. 3 (August 1, 2003): 1121–30. https://doi.org/10.1182/blood-2002-08-2545.
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  - Aguilar-Cordova, C. E., R. Macklin, M. L. Markert, C. A. Mickelson, D. G. Ando, X. O. Breakefield, T. C. Friedmann, et al. “U.S. Department of Health and Human Services National Institutes of Health Recombinant DNA Advisory Committee: Minutes of meeting: December 6, 2001.” Human Gene Therapy 13, no. 13 (September 27, 2002): 1663–73. https://doi.org/10.1089/10430340260201752.
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  - Hale, L. P., and M. L. Markert. “Corticosteroids may regulate epithelial cell differentiation and Hassall body formation in the thymus.” Clinical Immunology 103, no. 3 (June 1, 2002): S36–S36.
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  - Markert, M. L., M. Sarzotti, D. A. Ozaki, L. P. Hale, M. A. Alexieff, and J. Li. “Thymus transplantation after immunosuppression with thymoglobulin.” Clinical Immunology 103, no. 3 (June 1, 2002): S88–S88.
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  - Markert, M. L., M. Sarzotti, D. A. Ozaki, G. D. Sempowski, M. E. Rhein, L. P. Hale, M. A. Alexieff, and J. Li. “Thymic transplantation in complete DiGeorge syndrome.” Clinical Immunology 103, no. 3 (June 1, 2002): S77–78.
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  - Markert, M. L., A. P. Alvarez-McLeod, G. D. Sempowski, L. P. Hale, J. M. Horvatinovich, K. J. Weinhold, J. A. Bartlett, T. A. D’Amico, and B. F. Haynes. “Thymopoiesis in HIV-infected adults after highly active antiretroviral therapy.” Aids Res Hum Retroviruses 17, no. 17 (November 20, 2001): 1635–43. https://doi.org/10.1089/088922201753342040.
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  - Mickelson, C. A. “Department of Health and Human Services National Institutes of Health Recombinant DNA Advisory Committee. Minutes of meeting March 8-10, 2000.” Hum Gene Ther 11, no. 15 (October 10, 2000): 2159–92. https://doi.org/10.1089/104303400750001453.
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  - U.S. National Institutes of Health. Recombinant DNA Advisory Committee, Thomas A. “Prenatal gene tranfer: scientific, medical, and ethical issues: a report of the Recombinant DNA Advisory Committee.” Hum Gene Ther 11, no. 8 (May 1, 2000): 1211–29. https://doi.org/10.1089/10430340050015257.
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  - Markert, M. L., C. B. Hicks, J. A. Bartlett, J. L. Harmon, L. P. Hale, M. L. Greenberg, G. Ferrari, et al. “Effect of highly active antiretroviral therapy and thymic transplantation on immunoreconstitution in HIV infection.” Aids Res Hum Retroviruses 16, no. 5 (March 20, 2000): 403–13. https://doi.org/10.1089/088922200309061.
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  - Haynes, B. F., M. L. Markert, G. D. Sempowski, D. D. Patel, and L. P. Hale. “The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection.” Annu Rev Immunol 18 (2000): 529–60. https://doi.org/10.1146/annurev.immunol.18.1.529.
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  - Markert, M. L., A. Boeck, L. P. Hale, A. L. Kloster, T. M. McLaughlin, M. N. Batchvarova, D. C. Douek, et al. “Transplantation of thymus tissue in complete DiGeorge syndrome.” N Engl J Med 341, no. 16 (October 14, 1999): 1180–89. https://doi.org/10.1056/NEJM199910143411603.
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  - Collard, H. R., A. Boeck, T. M. Mc Laughlin, T. J. Watson, S. E. Schiff, L. P. Hale, and M. L. Markert. “Possible extrathymic development of nonfunctional T cells in a patient with complete DiGeorge syndrome.” Clin Immunol 91, no. 2 (May 1999): 156–62. https://doi.org/10.1006/clim.1999.4691.
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  - Buckley, R. H., S. E. Schiff, R. I. Schiff, L. Markert, L. W. Williams, J. L. Roberts, L. A. Myers, and F. E. Ward. “Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.” N Engl J Med 340, no. 7 (February 18, 1999): 508–16. https://doi.org/10.1056/NEJM199902183400703.
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  - “Recombinant DNA Advisory Committee. Department of Health and Human Services. National Institutes of Health. Minutes of meeting. March 10, 1998.” Hum Gene Ther 9, no. 16 (November 1, 1998): 2427–54. https://doi.org/10.1089/hum.1998.9.16-2427.
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  - “Recombinant DNA Advisory Committee. Department of Health and Human Services. National Institutes of Health. Minutes of meeting. December 15-16, 1997.” Hum Gene Ther 9, no. 11 (July 20, 1998): 1643–95. https://doi.org/10.1089/hum.1998.9.11-1643.
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  - Markert, M. L., D. S. Hummell, H. M. Rosenblatt, S. E. Schiff, T. O. Harville, L. W. Williams, R. I. Schiff, and R. H. Buckley. “Complete DiGeorge syndrome: persistence of profound immunodeficiency.” J Pediatr 132, no. 1 (January 1998): 15–21. https://doi.org/10.1016/s0022-3476(98)70478-0.
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  - Markert, M. L., M. Majure, T. O. Harville, G. Hulka, and K. Oldham. “Severe laryngomalacia and bronchomalacia in DiGeorge syndrome and CHARGE association.” Pediatr Pulmonol 24, no. 5 (November 1997): 364–69. https://doi.org/10.1002/(sici)1099-0496(199711)24:5<364::aid-ppul9>3.0.co;2-i.
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  - Buckley, R. H., R. I. Schiff, S. E. Schiff, M. L. Markert, L. W. Williams, T. O. Harville, J. L. Roberts, and J. M. Puck. “Human severe combined immunodeficiency: genetic, phenotypic, and functional diversity in one hundred eight infants.” J Pediatr 130, no. 3 (March 1997): 378–87. https://doi.org/10.1016/s0022-3476(97)70199-9.
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  - Davis, C. M., T. M. McLaughlin, T. J. Watson, R. H. Buckley, S. E. Schiff, L. P. Hale, B. F. Haynes, and M. L. Markert. “Normalization of the peripheral blood T cell receptor V beta repertoire after cultured postnatal human thymic transplantation in DiGeorge syndrome.” J Clin Immunol 17, no. 2 (March 1997): 167–75. https://doi.org/10.1023/a:1027382600143.
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  - Markert, M. L., D. D. Kostyu, F. E. Ward, T. M. McLaughlin, T. J. Watson, R. H. Buckley, S. E. Schiff, et al. “Successful formation of a chimeric human thymus allograft following transplantation of cultured postnatal human thymus.” J Immunol 158, no. 2 (January 15, 1997): 998–1005.
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  - Markert, M. L., B. D. Finkel, T. M. McLaughlin, T. J. Watson, H. R. Collard, C. P. McMahon, L. G. Andrews, M. J. Barrett, and F. E. Ward. “Mutations in purine nucleoside phosphorylase deficiency.” Hum Mutat 9, no. 2 (1997): 118–21. https://doi.org/10.1002/(SICI)1098-1004(1997)9:2<118::AID-HUMU3>3.0.CO;2-5.
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  - Markert, M. L., T. J. Watson, T. M. McLaughlin, D. S. Hummel, H. M. Rosenblatt, S. E. Schiff, T. O. Harville, L. Williams, R. I. Schiff, and R. H. Buckley. “Complete DiGeorge syndrome: Persistence of profound immunodeficiency.” Journal of Allergy and Clinical Immunology 99, no. 1 (January 1, 1997): 1599–1599.
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  - Markert, M. L., T. J. Watson, I. Kaplan, L. P. Hale, and B. F. Haynes. “The human thymic microenvironment during organ culture.” Clin Immunol Immunopathol 82, no. 1 (January 1997): 26–36. https://doi.org/10.1006/clin.1996.4266.
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  - Markert, M. L. “Thymic transplantation for digeorge syndrome.” Faseb Journal 10, no. 6 (December 1, 1996).
  - Garry, R. F., C. D. Fermin, P. F. Kohler, M. L. Markert, and H. Luo. “Antibodies against retroviral proteins and nuclear antigens in a subset of idiopathic CD4+ T lymphocytopenia patients.” Aids Res Hum Retroviruses 12, no. 10 (July 1, 1996): 931–40. https://doi.org/10.1089/aid.1996.12.931.
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  - Markert, M. L. “Perspective: research highlights at the Duke University center for AIDS research. Immunoreconstitution in HIV infection: the role of the thymus.” Aids Res Hum Retroviruses 12, no. 9 (June 10, 1996): 751–55. https://doi.org/10.1089/aid.1996.12.751.
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  - Markert, M. L., C. M. Davis, F. E. Ward, D. D. Kostyu, R. H. Buckley, S. E. Schiff, T. J. Watson, et al. “Thymic transplantation for digeorge syndrome.” Faseb Journal 10, no. 6 (April 30, 1996): 373–373.
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  - Buckley, R. H., R. E. Schiff, S. E. Schiff, M. L. Markert, L. W. Williams, T. O. Harville, J. L. Roberts, and J. Puck. “Human severe combined immunodeficiency (SCID): Genetic, phenotypic and functional diversity in 95 infants.” Pediatric Research 39, no. 4 (April 1, 1996): 41–41.
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  - Russell, S. M., N. Tayebi, H. Nakajima, M. C. Riedy, J. L. Roberts, M. J. Aman, T. S. Migone, et al. “Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.” Science 270, no. 5237 (November 3, 1995): 797–800. https://doi.org/10.1126/science.270.5237.797.
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  - MARKERT, M. L., T. J. WATSON, T. M. MCLAUGHLIN, C. A. MCGUIRE, F. E. WARD, D. KOSTYU, L. P. HALE, et al. “DEVELOPMENT OF T-CELL FUNCTION AFTER POSTNATAL THYMIC TRANSPLANTATION FOR DIGEORGE-SYNDROME.” American Journal of Human Genetics 57, no. 4 (October 1, 1995): 64–64.
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  - Nelson, D. M., K. A. Butters, M. L. Markert, N. L. Reinsmoen, and R. S. McIvor. “Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression.” J Immunol 154, no. 6 (March 15, 1995): 3006–14.
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  - BUCKLEY, R. H., R. I. SCHIFF, M. L. MARKERT, L. W. WILLIAMS, T. O. HARVILLE, and S. E. SCHIFF. “IMMUNOBIOLOGY OF HUMAN SEVERE COMBINED IMMUNODEFICIENCY.” Faseb Journal 9, no. 4 (March 10, 1995): A780–A780.
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  - Markert, M. L. “Molecular basis of adenosine deaminase deficiency.” Immunodeficiency 5, no. 2 (1994): 141–57.
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  - Buckley, R. H., S. E. Schiff, R. I. Schiff, J. L. Roberts, M. L. Markert, W. Peters, L. W. Williams, and F. E. Ward. “Haploidentical bone marrow stem cell transplantation in human severe combined immunodeficiency.” Semin Hematol 30, no. 4 Suppl 4 (October 1993): 92–101.
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  - Gossage, D. L., C. J. Norby-Slycord, M. S. Hershfield, and M. L. Markert. “A homozygous 5 base-pair deletion in exon 10 of the adenosine deaminase (ADA) gene in a child with severe combined immunodeficiency and very low levels of ADA mRNA and protein.” Hum Mol Genet 2, no. 9 (September 1993): 1493–94. https://doi.org/10.1093/hmg/2.9.1493.
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  - Atasoy, U., C. J. Norby-Slycord, and M. L. Markert. “A missense mutation in exon 4 of the human adenosine deaminase gene causes severe combined immunodeficiency.” Hum Mol Genet 2, no. 8 (August 1993): 1307–8. https://doi.org/10.1093/hmg/2.8.1307.
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  - Buckley, R. H., S. E. Schiff, R. I. Schiff, J. L. Roberts, M. L. Markert, W. Peters, L. W. Williams, et al. “Haploidentical bone marrow stem cell transplantation in human severe combined immunodeficiency.” Seminars in Hematology 30, no. 4 SUPPL. 4 (January 1, 1993): 92–104.
  - Aust, M. R., L. G. Andrews, M. J. Barrett, C. J. Norby-Slycord, and M. L. Markert. “Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.” Am J Hum Genet 51, no. 4 (October 1992): 763–72.
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  - Andrews, L. G., and M. L. Markert. “Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency.” J Biol Chem 267, no. 11 (April 15, 1992): 7834–38.
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  - Markert, M. L. “Molecular biology and allergy: current status and future prospects.” Pediatric Allergy and Immunology 3, no. 2 (January 1, 1992): 49–60. https://doi.org/10.1111/j.1399-3038.1992.tb00027.x.
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  - Markert, M. L. “Purine nucleoside phosphorylase deficiency.” Immunodefic Rev 3, no. 1 (1991): 45–81.
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  - Markert, M. L., C. Norby-Slycord, and F. E. Ward. “A high proportion of ADA point mutations associated with a specific alanine-to-valine substitution.” Am J Hum Genet 45, no. 3 (September 1989): 354–61.
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  - Markert, M. L., J. J. Hutton, D. A. Wiginton, J. C. States, and R. E. Kaufman. “Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements.” J Clin Invest 81, no. 5 (May 1988): 1323–27. https://doi.org/10.1172/JCI113458.
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  - Markert, M. L., M. S. Hershfield, R. I. Schiff, and R. H. Buckley. “Adenosine deaminase and purine nucleoside phosphorylase deficiencies: evaluation of therapeutic interventions in eight patients.” J Clin Immunol 7, no. 5 (September 1987): 389–99. https://doi.org/10.1007/BF00917017.
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  - Markert, M. L., M. S. Hershfield, D. A. Wiginton, J. C. States, F. E. Ward, S. H. Bigner, R. H. Buckley, R. E. Kaufman, and J. J. Hutton. “Identification of a deletion in the adenosine deaminase gene in a child with severe combined immunodeficiency.” J Immunol 138, no. 10 (May 15, 1987): 3203–6.
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  - Hershfield, M. S., R. H. Buckley, M. L. Greenberg, A. L. Melton, R. Schiff, C. Hatem, J. Kurtzberg, M. L. Markert, R. H. Kobayashi, and A. L. Kobayashi. “Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase.” N Engl J Med 316, no. 10 (March 5, 1987): 589–96. https://doi.org/10.1056/NEJM198703053161005.
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  - Markert, M. L., and R. H. Buckley. “Natural-killer-cell function and bone marrow transplantation.” N Engl J Med 315, no. 22 (November 27, 1986): 1418–19. https://doi.org/10.1056/NEJM198611273152216.
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  - Buckley, R. H., S. E. Schiff, H. A. Sampson, R. I. Schiff, M. L. Markert, A. P. Knutsen, M. S. Hershfield, A. T. Huang, G. H. Mickey, and F. E. Ward. “Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation.” J Immunol 136, no. 7 (April 1, 1986): 2398–2407.
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  - MCKINNEY, R. E., M. L. MARKERT, L. W. WILLIAMS, R. H. BUCKLEY, and C. M. WILFERT. “THE USE OF INTRAVENOUS IMMUNOGLOBULIN (IVIG) PREPARATIONS IN THE TREATMENT OF CHRONIC ENTEROVIRAL INFECTIONS.” Pediatric Research 20, no. 4 (April 1, 1986): A297–A297.
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  - Markert, M. L., and P. Cresswell. “Human B cell alloantigens: expression of MB and MT determinants.” J Immunol 128, no. 5 (May 1982): 2004–8.
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  - Markert, M. L., and P. Cresswell. “Human B cell alloantigens; alpha subunit variability.” J Immunol 128, no. 5 (May 1982): 1999–2003.
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  - Markert, M. L., and P. Cresswell. “Polymorphism of human B-cell alloantigens: evidence for three loci within the HLA system.” Proc Natl Acad Sci U S A 77, no. 10 (October 1980): 6101–4. https://doi.org/10.1073/pnas.77.10.6101.
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- Book Sections
  - Markert, M. L. “Defects in thymic development.” In Stiehm’s Immune Deficiencies: Inborn Errors of Immunity, 357–80, 2020. https://doi.org/10.1016/B978-0-12-816768-7.00013-2.
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  - Markert, M. L., E. A. McCarthy, S. E. Gupton, and A. P. Lim. “Cultured thymus tissue transplantation.” In Stiehm’s Immune Deficiencies: Inborn Errors of Immunity, 1229–40, 2020. https://doi.org/10.1016/B978-0-12-816768-7.00059-4.
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  - Markert, M. L. “Defects in Thymic Development: DiGeorge/CHARGE/Chromosome 22q11.2 Deletion.” In Stiehm’s Immune Deficiencies, 221–42, 2014. https://doi.org/10.1016/B978-0-12-405546-9.00008-X.
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  - Markert, M. L., B. H. Devlin, and E. A. McCarthy. “Thymic reconstitution.” In Clinical Immunology: Principles and Practice: Fourth Edition, 1032–38, 2013. https://doi.org/10.1016/B978-0-7234-3691-1.00023-4.
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  - Markert, M. L., and B. H. Devlin. “Thymic reconstitution: Characteristics of Naive T Cells.” In Clinical Immunology: Principles and Practice Expert Consult: Online and Print, 1253–61, 2008. https://doi.org/10.1016/B978-0-323-04404-2.10084-3.
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- Conference Papers
  - Kang, Lillian, Joseph R. Nellis, Nicholas D. Andersen, Henry E. Rice, Michael P. Carboni, M Louise Markert, and Joseph W. Turek. “Concurrent cultured thymus tissue implantation and orthotopic heart transplantation: A case report on the first clinical experience.” In Pediatric Transplantation, Vol. 26, 2022.
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  - Baloh, Carolyn, M Louise Markert, Vandana Shashi, and John Sleasman. “Predicting Autoimmunity Development in 22q11.2DS.” In Journal of Allergy and Clinical Immunology, 145:AB81–AB81. MOSBY-ELSEVIER, 2020.
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  - Kilgore, Jacob, Carolyn Baloh, Adam Blatt, Rebecca Young, M Louise Markert, Michael J. Smith, and John W. Sleasman. “The Association Between T-cell Immune Deficiency and the Risk of Serious Infection in Children with Thymic Hypoplasia Cared for at Duke University.” In Journal of Clinical Immunology, 40:S48–S48, 2020.
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  - Oers, Nicolai S. van, Qiumei Du, Huynh Larry, Fatma Coskun, Igor Dozmorov, Prithvi Raj, Shaheen Khan, Christian Wysocki, Mary Louise Markert, and Maria Teresa de la Morena. “22q11.2 Deletion Syndrome (DiGeorge) and Mutations in Forkhead Box N1 (FOXN1) cause a Thymic Hypoplasia through distinct Developmental Processes.” In Journal of Immunology, Vol. 202. AMER ASSOC IMMUNOLOGISTS, 2019.
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  - Bosticardo, Marita, Francesca Pala, Enrica Calzoni, Cameron Gardner, Kerry Dobbs, Suk See De Ravin, Nicholas Hartog, et al. “Artificial Thymic Organoids Represent a Reliable and Quick Tool to Study T Cell Differentiation in Human Bone Marrow Samples from Patients with Severe T Cell Immunodeficiency.” In Journal of Clinical Immunology, 39:S51–52. SPRINGER/PLENUM PUBLISHERS, 2019.
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  - Du, Qiumei, Larry Huynh, Fatma Coskun, Igor Dozmorov, Prithvi Raj, Shaheen Khan, Christian A. Wysocki, M Louise Markert, Maria Teresa de la Morena, and Nicolai S. van Oers. “Novel Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Cause a Severe Immunodeficiency Without Alopecia or Nail Dystrophy.” In Journal of Clinical Immunology, 39:S127–28. SPRINGER/PLENUM PUBLISHERS, 2019.
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  - Gupton, Stephanie E., Elizabeth A. McCarthy, and Mary Louise Markert. “Guidance for the Care of Patients Undergoing Cultured Thymus Tissue Transplantation (RVT-802).” In Journal of Clinical Immunology, 39:S49–50. SPRINGER/PLENUM PUBLISHERS, 2019.
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  - Yates, Tyler R., Jennifer Puck, Morna J. Dorsey, Ziad Khatib, Karin Chen, Vivian Hernandez-Trujillo, William Blouin, Ralph Quinones, Erwin W. Gelfand, and M Louise Markert. “Investigational Cultured Thymus Tissue Transplantation (RVT-802) Following Failed Stem Cell Transplantation in Athymic Patients.” In Journal of Clinical Immunology, 39:S26–27. SPRINGER/PLENUM PUBLISHERS, 2019.
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  - Oers, Nicolai S. van, Shaheen Khan, Larry K. Hunyh, Qiumei Du, Grace T. Padron, Erika Molina, Igor Dozmorov, M Louise Markert, and M Teresa de la Morena. “Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Lead to a Severe Immunodeficiency but Normal Hair and Nail Development in Patients.” In Journal of Immunology, Vol. 200. AMER ASSOC IMMUNOLOGISTS, 2018.
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  - Padron, Grace Toledo, Stephanie Gupton, and Mary Louise Markert. “THE CHANGING FACE OF COMPLETE DIGEORGE ANOMALY: ATHYMIC PATIENTS WITH CHARGE SYNDROME.” In Journal of Clinical Immunology, 37:200–201. SPRINGER/PLENUM PUBLISHERS, 2017.
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  - Agboola, Olabunmi, Jun Chen, and M Louise Markert. “Thymus Transplantation for Chronic Graft Versus Host Disease.” In Journal of Allergy and Clinical Immunology, 139:AB185–AB185. Elsevier BV, 2017. https://doi.org/10.1016/j.jaci.2016.12.605.
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  - Agada, Noah O., Suellen M. Yin, Jonathan S. Tam, Matthew S. Kelly, and M Louise Markert. “Disseminated Atypical Mycobacterial Infection in Three Patients with Complete Digeorge Anomaly.” In Journal of Allergy and Clinical Immunology, 135:AB10–AB10. Elsevier BV, 2015. https://doi.org/10.1016/j.jaci.2014.12.968.
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  - Yu, Xiaomin, Jorge Almeida, Sam Darko, Mirjam van der Burg, Suk See DeRavin, Harry Malech, Andrew Gennery, et al. “Human Syndromes of Immune Deficiency and Dysregulation are Characterized by Distinct Defects in T-Cell Receptor Repertoire Development.” In Journal of Clinical Immunology, 34:350–51. SPRINGER/PLENUM PUBLISHERS, 2014.
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  - Lee, J. H., M. L. Markert, C. P. Hornik, E. A. McCarthy, S. E. Gupton, I. M. Cheifetz, and D. A. Turner. “SEPSIS INCREASES MORBIDITY OF CRITICALLY ILL INFANTS WITH COMPLETE DIGEORGE ANOMALY TREATED WITH THYMUS TRANSPLANTATION.” In Intensive Care Medicine, 39:S412–S412. SPRINGER, 2013.
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  - Markert, M. L., B. H. Devlin, and E. A. McCarthy. “Thymus Defects/Transplant and Problems Associated with Immune Reconstitution.” In Proceedings of the 15th Meeting of the European Society Immunodeficiencies (Esid), edited by A. Etzioni and E. Gambineri, 99–104. MEDIMOND S R L, 2013.
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  - Chinn, I. K., J. A. Olson, M. A. Skinner, E. A. McCarthy, S. E. Gupton, F. A. Bonilla, R. L. Roberts, M. G. Kanariou, B. H. Devlin, and M. L. Markert. “Mechanisms of Tolerance to Parental Parathyroid Tissue when Combined with Human Allogeneic Thymus Transplantation.” In Journal of Allergy and Clinical Immunology, 125:AB55–AB55. Elsevier BV, 2010. https://doi.org/10.1016/j.jaci.2009.12.252.
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  - Li, Bin, Jie Li, Blythe H. Devlin, and Mary Louise Markert. “MHC class I restriction in DiGeorge anomaly patients after allogeneic thymus transplantation.” In Journal of Immunology, Vol. 182. AMER ASSOC IMMUNOLOGISTS, 2009.
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  - Cowell, Lindsay Grey, Blythe Devlin, Chia-San Hsieh, Susan Harley, Jie Li, and Mary Louise Markert. “The roles of recombination signal sequence efficiency and location within the TCR beta locus on the relative frequencies with which V beta gene segments participate in V(D)J recombination.” In Faseb Journal, Vol. 22. FEDERATION AMER SOC EXP BIOL, 2008.
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  - CHINN, I., J. OLSONJR, M. SKINNER, E. MCCARTHY, S. GUPTON, F. BONILLA, R. ROBERTS, M. KANARIOU, B. DEVLIN, and M. MARKERT. “Combined Thymus and Parathyroid Allotransplantation in Complete DiGeorge Anomaly.” In Journal of Allergy and Clinical Immunology, 121:S269–S269. Elsevier BV, 2008. https://doi.org/10.1016/j.jaci.2007.12.1067.
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  - Chinn, I. K., B. H. Devlin, M. J. Alexieff, J. Li, S. E. Gupton, E. A. McCarthy, and M. L. Markert. “Tolerance To Allogeneic Thymus Transplantation In Complete DiGeorge Syndrome.” In Journal of Allergy and Clinical Immunology, 119:S12–S12. Elsevier BV, 2007. https://doi.org/10.1016/j.jaci.2006.11.062.
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  - Chinn, Ivan, Blythe Devlin, and M Louise Markert. “Development of Regulatory T Cells After Thymus Transplantation in Subjects with Complete DiGeorge Syndrome.” In Clinical Immunology, 123:S42–43. Elsevier BV, 2007. https://doi.org/10.1016/j.clim.2007.03.297.
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  - Chinn, I. K., B. H. Devlin, M. A. Alexieff, J. Li, E. McCarthy, M. A. Skinner, J. A. Olson, and M. L. Markert. “Parathyroid Gland Transplantation without Posttransplantation Immunosuppression.” In Journal of Allergy and Clinical Immunology, 117:S108–S108. Elsevier BV, 2006. https://doi.org/10.1016/j.jaci.2005.12.431.
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  - Devlin, B. H., J. Li, M. Alexieff, S. Harley, E. McCarthy, M. He, T. B. Kepler, and M. L. Markert. “Time course of normalization of T cell receptor repertoire in a complete DiGeorge syndrome patient post-thymus transplantation.” In Clinical Immunology, 116:285–86. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005.
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  - Markert, M. L., B. H. Devlin, M. A. Alexieff, J. Li, E. McCarthy, M. A. Skinner, and J. A. Olson. “Parathyroid and thymus transplantation in complete DiGeorge syndrome.” In Clinical Immunology, 116:294–95. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005.
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  - Kepler, T. B., M. He, J. Tomfohr, S. Fadel, M. Sarzotti, and M. L. Markert. “Statistical methods for quantitative analysis of TCR diversity via immunoscope.” In Faseb Journal, 18:A1181–A1181. FEDERATION AMER SOC EXP BIOL, 2004.
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  - Tomfohr, J., M. He, L. Cowell, M. Sarzotti-Kelsoe, M. L. Markert, and T. B. Kepler. “T cell competition and repertoire diversity: the roles of TCR-specific and non-specific resource limitation determined through multivariate data analysis and computational modeling.” In Faseb Journal, 18:A798–A798. FEDERATION AMER SOC EXP BIOL, 2004.
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  - ATASOY, U., and M. L. MARKERT. “NONSENSE MUTATIONS DESTABILIZE ADA MESSENGER-RNA TRANSCRIPTS AT THE NUCLEAR-LEVEL.” In Pediatric Research, 37:A8–A8. WILLIAMS & WILKINS, 1995.
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  - HERSHFIELD, M. S., R. H. BUCKLEY, M. L. GREENBERG, A. L. MELTON, R. H. KOBAYASHI, A. L. KOBAYASHI, R. SCHIFF, J. KURTZBERG, M. L. MARKERT, and A. ABUCHOWSKI. “TREATMENT OF ADENOSINE-DEAMINASE DEFICIENCY WITH POLYETHYLENE-GLYCOL MODIFIED ADENOSINE-DEAMINASE (PEG-ADA).” In Clinical Research, 35:A593–A593. SLACK INC, 1987.
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  - MARKERT, M. L., M. S. HERSHFIELD, S. E. SCHIFF, H. A. SAMPSON, R. I. SCHIFF, and R. H. BUCKLEY. “IMMUNODEFICIENCY WITH PURINE SALVAGE PATHWAY ENZYME DEFICIENCIES - EVALUATION OF THERAPIES.” In Journal of Allergy and Clinical Immunology, 77:190–190. MOSBY-YEAR BOOK INC, 1986.
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  - MARKERT, M. L., H. WARNER, and P. CRESSWELL. “CHIMPANZEE ANTISERA DIFFERENTIATE BETWEEN HLA-DR AND MT ANTIGENS.” In Federation Proceedings, 40:1053–1053. FEDERATION AMER SOC EXP BIOL, 1981.
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