Jeffrey R. Marks
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery
I have been engaged in basic and applied cancer research for over 28 years beginning with my post-doctoral fellowship under Arnold Levine at Princeton. Since being appointed to the faculty in the Department of Surgery at Duke, my primary interest has been towards understanding breast and ovarian cancer. I am a charter member of the NCI-Early Detection Research Network (EDRN) and have been an integral scientist in the breast and gynecologic collaborative group for 15 years including leading this group for a 5 year period. I am also a major contributor to the Cancer Genome Atlas and have worked in this context for the past 4 years. My research interests are in the molecular etiology of these diseases and understanding how key genetic events contribute to their onset and progression. My work has been very multi-disciplinary incorporating quantitative, population, genetic, and behavioral approaches. I consider my specialty to be in the area of using human breast and ovarian cancer as the primary and only authentic model system to understand these diseases.
Current Appointments & Affiliations
- Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Surgical Sciences, Surgery 2022
- Professor in Surgery, Surgery, Surgical Sciences, Surgery 2019
- Professor of Pathology, Pathology, Clinical Science Departments 2019
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1988
Contact Information
- B216, LSRC, Duke University, Durham, NC 27710
- Box 3873 Med Ctr, Durham, NC 27710
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marks003@mc.duke.edu
(919) 684-6133
- Background
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Education, Training, & Certifications
- Ph.D., University of California - San Diego 1985
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Previous Appointments & Affiliations
- Associate Professor of Pathology, Pathology, Clinical Science Departments 2009 - 2019
- Associate Professor of Surgery, Surgery, Surgical Sciences, Surgery 2009 - 2019
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 1998 - 2009
- Associate Professor in Surgery, Surgery, Surgical Sciences, Surgery 1998 - 2009
- Associate Research Professor of Experimental Surgery in the Department of Surgery, Surgery, Clinical Science Departments 1994 - 1998
- Assistant Research Professor of Pathology, Pathology, Clinical Science Departments 1997 - 1998
- Assistant Research Professor of Experimental Surgery in the Department of Surgery, Surgery, Clinical Science Departments 1993 - 1994
- Recognition
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In the News
- Research
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Selected Grants
- Dynamic imaging and tissue biomarker models to delineate indolent from aggressive breast calcifications awarded by National Institutes of Health 2022 - 2027
- Molecular and Radiologic Predictors of Invasion in a DCIS Active Surveillance Cohort awarded by Breast Cancer Research Foundation 2021 - 2023
- sCRA Sample Agreement awarded by Cleveland Diagnostics, Inc 2021 - 2023
- Ovarian Cancer Survival in African-American Women awarded by Emory University 2020 - 2023
- Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2023
- Prevent Ductal Carcinoma in Situ Invasive Overtreatment Now - PRECISION awarded by MD Anderson Cancer Center 2017 - 2023
- Characterizing Molecular Subtypes of Ovarian Cancer in African-American Women awarded by University of Utah 2017 - 2022
- Breast Cancer Detection Consortium awarded by National Institutes of Health 2016 - 2022
- Discovery and validation of putative oncogenic ROS1 alterations in metastatic breast cancer awarded by Metavivor 2020 - 2022
- Genomic Diversity and the Microenvironment as Drivers of Progression in DCIS awarded by Department of Defense 2014 - 2021
- Molecular and Radiologic Predictors of Invasion in a DCIS Active Surveillance Cohort awarded by Breast Cancer Research Foundation 2019 - 2020
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Can contrast dynamics in breast MRI predict genomic intra-tumor heterogeneity awarded by Bracco Diagnostics, Inc. 2016 - 2020
- Molecular and Radiologic Predictors of Invasion in a DCIS Active Surveillance Cohort awarded by Breast Cancer Research Foundation 2018 - 2019
- (PQC3) Genomic Diversity and the Microenvironment as Drivers of Metastasis in DCIS awarded by National Institutes of Health 2014 - 2019
- Fibulin-3 as a Novel Biomarker and Trget in the Breast Tumor Microenvironment awarded by Susan G. Komen Breast Cancer Foundation 2015 - 2018
- Molecular and Radiologic Predictors of Invasion in a DCIS Active Surveillance Cohort awarded by Breast Cancer Research Foundation 2016 - 2018
- Gene expression programs of lactic acidosis in human cancers awarded by National Institutes of Health 2007 - 2018
- A Simple System for Early Detection of Breast Cancer awarded by Arizona State University 2014 - 2017
- Atlantic Breast and Gynecologic Clinical Validation Center awarded by National Institutes of Health 1999 - 2016
- Integrating Population and Basic Science in Cancer Research awarded by National Institutes of Health 2009 - 2015
- Clinical Oncology Research Career Development Program awarded by National Institutes of Health 2009 - 2015
- TCGA - Breast Cancer Tissue Acquisition awarded by National Institutes of Health 2010 - 2015
- Epidemiology of Ovarian Cancer in African-American Women awarded by National Institutes of Health 2010 - 2015
- Integration of Oncogenic Networks in Cancer Phenotypes awarded by National Institutes of Health 2004 - 2011
- MAL Promoter Hypermethylation and its Implications in Breast Cancer awarded by National Institutes of Health 2007 - 2010
- Developing Biomarker-Based Prognostics in Breast Cancer awarded by National Institutes of Health 2004 - 2009
- Biomarker Studies for Novel Anti-Cancer Agents awarded by National Institutes of Health 2003 - 2008
- Improving genomic prediction models in breast cancer. awarded by National Institutes of Health 2004 - 2007
- PPARy: Biomarker for Breast Cancer in Older Women awarded by National Institutes of Health 2005 - 2007
- Tissue Transglutaminase And Breast Cancer Biology awarded by National Institutes of Health 1997 - 2003
- Characterization of BRCA2 awarded by National Institutes of Health 1908 - 2002
- Immune Response to Breast Ductal Carcinoma In Situ awarded by National Institutes of Health 1992 - 2000
- Tissue Transglutaminase And Breast Cancer Biology awarded by National Institutes of Health 1997 - 1999
- Characterization Of Brca2 awarded by National Institutes of Health 1997 - 1999
- Planning A Program Of Research In Early Breast Cancer awarded by National Institutes of Health 1994 - 1998
- Spore In Breast Cancer awarded by National Institutes of Health 1995 - 1998
- Spore In Breast Cancer awarded by National Institutes of Health 1995 - 1998
- Spore In Breast Cancer awarded by National Institutes of Health 1995 - 1998
- Surrogate Markers Of Tumor Specific Immunity awarded by National Institutes of Health 1994 - 1998
- Molecularly-Defined Taa As Human Anti-Tumor Ctl Targets awarded by National Institutes of Health 1993 - 1997
- Molecularly-Defined Taa As Human Anti-Tumor Ctl Targets awarded by National Institutes of Health 1992 - 1997
- Molecularly-Defined Taa As Human Anti-Tumor Ctl Targets awarded by National Institutes of Health 1992 - 1997
- Retinoid Signaling Defects In Breast Cancer awarded by National Institutes of Health 1996 - 1997
- Retinoid Signalling Defects In Breast Cancer awarded by National Institutes of Health 1993 - 1997
- P53 In Human Breast Cancer awarded by National Institutes of Health 1993 - 1995
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Schildkraut, Joellen M., Courtney Johnson, Lauren F. Dempsey, Bo Qin, Paul Terry, Maxwell Akonde, Edward S. Peters, et al. “Survival of epithelial ovarian cancer in Black women: a society to cell approach in the African American cancer epidemiology study (AACES).” Cancer Causes Control, December 15, 2022, 1–15. https://doi.org/10.1007/s10552-022-01660-0.Full Text Link to Item
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Strand, Siri H., Belén Rivero-Gutiérrez, Kathleen E. Houlahan, Jose A. Seoane, Lorraine M. King, Tyler Risom, Lunden A. Simpson, et al. “Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts.” Cancer Cell 40, no. 12 (December 12, 2022): 1521-1536.e7. https://doi.org/10.1016/j.ccell.2022.10.021.Full Text Link to Item
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Sobhani, Faranak, Sathya Muralidhar, Azam Hamidinekoo, Allison H. Hall, Lorraine M. King, Jeffrey R. Marks, Carlo Maley, Hugo M. Horlings, E Shelley Hwang, and Yinyin Yuan. “Spatial interplay of tissue hypoxia and T-cell regulation in ductal carcinoma in situ.” Npj Breast Cancer 8, no. 1 (September 15, 2022): 105. https://doi.org/10.1038/s41523-022-00419-9.Full Text Link to Item
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Lips, Esther H., Tapsi Kumar, Anargyros Megalios, Lindy L. Visser, Michael Sheinman, Angelo Fortunato, Vandna Shah, et al. “Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.” Nat Genet 54, no. 6 (June 2022): 850–60. https://doi.org/10.1038/s41588-022-01082-3.Full Text Link to Item
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Peres, Lauren C., Christelle Colin-Leitzinger, Sweta Sinha, Jeffrey R. Marks, Jose R. Conejo-Garcia, Anthony J. Alberg, Elisa V. Bandera, et al. “Racial Differences in the Tumor Immune Landscape and Survival of Women with High-Grade Serous Ovarian Carcinoma.” Cancer Epidemiol Biomarkers Prev 31, no. 5 (May 4, 2022): 1006–16. https://doi.org/10.1158/1055-9965.EPI-21-1334.Full Text Link to Item
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Hou, Rui, Yifan Peng, Lars J. Grimm, Yinhao Ren, Maciej A. Mazurowski, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, E Shelley Hwang, and Joseph Y. Lo. “Anomaly Detection of Calcifications in Mammography Based on 11,000 Negative Cases.” Ieee Trans Biomed Eng 69, no. 5 (May 2022): 1639–50. https://doi.org/10.1109/TBME.2021.3126281.Full Text Link to Item
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Gosling, Sarah, Doriana Calabrese, Jayakrupakar Nallala, Charlene Greenwood, Sarah Pinder, Lorraine King, Jeffrey Marks, et al. “A multi-modal exploration of heterogeneous physico-chemical properties of DCIS breast microcalcifications.” Analyst 147, no. 8 (April 11, 2022): 1641–54. https://doi.org/10.1039/d1an01548f.Full Text Link to Item
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Hou, Rui, Lars J. Grimm, Maciej A. Mazurowski, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, Thomas Lynch, et al. “Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.” Radiology 303, no. 1 (April 2022): 54–62. https://doi.org/10.1148/radiol.210407.Full Text Link to Item
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Risom, Tyler, David R. Glass, Inna Averbukh, Candace C. Liu, Alex Baranski, Adam Kagel, Erin F. McCaffrey, et al. “Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma.” Cell 185, no. 2 (January 20, 2022): 299-310.e18. https://doi.org/10.1016/j.cell.2021.12.023.Full Text Link to Item
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Fortunato, Angelo, Diego Mallo, Shawn M. Rupp, Lorraine M. King, Timothy Hardman, Joseph Y. Lo, Allison Hall, Jeffrey R. Marks, E Shelley Hwang, and Carlo C. Maley. “A new method to accurately identify single nucleotide variants using small FFPE breast samples.” Brief Bioinform 22, no. 6 (November 5, 2021). https://doi.org/10.1093/bib/bbab221.Full Text Link to Item
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Lin, Chao-Chieh, Nathaniel W. Mabe, Yi-Tzu Lin, Wen-Hsuan Yang, Xiaohu Tang, Lisa Hong, Tianai Sun, et al. “RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence.” Cell Death Differ 27, no. 7 (July 2020): 2234–47. https://doi.org/10.1038/s41418-020-0499-y.Full Text Link to Item
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Hou, Rui, Maciej A. Mazurowski, Lars J. Grimm, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, Eun-Sil Shelley Hwang, and Joseph Y. Lo. “Prediction of Upstaged Ductal Carcinoma In Situ Using Forced Labeling and Domain Adaptation.” Ieee Trans Biomed Eng 67, no. 6 (June 2020): 1565–72. https://doi.org/10.1109/TBME.2019.2940195.Full Text Link to Item
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Hwang, E Shelley, Terry Hyslop, Laura H. Hendrix, Stephanie Duong, Isabelle Bedrosian, Elissa Price, Abigail Caudle, et al. “Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance).” J Clin Oncol 38, no. 12 (April 20, 2020): 1284–92. https://doi.org/10.1200/JCO.19.00510.Full Text Link to Item
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Rozenblatt-Rosen, Orit, Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood, Orr Ashenberg, et al. “The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.” Cell 181, no. 2 (April 16, 2020): 236–49. https://doi.org/10.1016/j.cell.2020.03.053.Full Text Open Access Copy Link to Item
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Ryser, Marc D., Diego Mallo, Allison Hall, Timothy Hardman, Lorraine M. King, Sergei Tatishchev, Inmaculada C. Sorribes, et al. “Minimal barriers to invasion during human colorectal tumor growth.” Nat Commun 11, no. 1 (March 9, 2020): 1280. https://doi.org/10.1038/s41467-020-14908-7.Full Text Link to Item
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ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, A. D. “Pan-cancer analysis of whole genomes.” Nature 578, no. 7793 (February 2020): 82–93. https://doi.org/10.1038/s41586-020-1969-6.Full Text Link to Item
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Fackler, Mary Jo, Soonweng Cho, Leslie Cope, Edward Gabrielson, Kala Visvanathan, Kathleen Wilsbach, Danielle Meir-Levi, et al. “DNA methylation markers predict recurrence-free interval in triple-negative breast cancer.” Npj Breast Cancer 6 (2020): 3. https://doi.org/10.1038/s41523-020-0145-3.Full Text Link to Item
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Cocce, Kimberly J., Jeff S. Jasper, Taylor K. Desautels, Logan Everett, Suzanne Wardell, Thomas Westerling, Robert Baldi, et al. “The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer.” Cell Rep 29, no. 4 (October 22, 2019): 889-903.e10. https://doi.org/10.1016/j.celrep.2019.09.032.Full Text Link to Item
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Thorsson, Vésteinn, David L. Gibbs, Scott D. Brown, Denise Wolf, Dante S. Bortone, Tai-Hsien Ou Yang, Eduard Porta-Pardo, et al. “The Immune Landscape of Cancer.” Immunity 51, no. 2 (August 20, 2019): 411–12. https://doi.org/10.1016/j.immuni.2019.08.004.Full Text Link to Item
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Hu, Qingsong, Youqiong Ye, Li-Chuan Chan, Yajuan Li, Ke Liang, Aifu Lin, Sergey D. Egranov, et al. “Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.” Nat Immunol 20, no. 7 (July 2019): 835–51. https://doi.org/10.1038/s41590-019-0400-7.Full Text Link to Item
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Mazurowski, Maciej A., Ashirbani Saha, Michael R. Harowicz, Elizabeth Hope Cain, Jeffrey R. Marks, and P Kelly Marcom. “Association of distant recurrence-free survival with algorithmically extracted MRI characteristics in breast cancer.” J Magn Reson Imaging 49, no. 7 (June 2019): e231–40. https://doi.org/10.1002/jmri.26648.Full Text Link to Item
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Hu, Qingsong, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, et al. “LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.” Cell Res 29, no. 4 (April 2019): 286–304. https://doi.org/10.1038/s41422-018-0134-3.Full Text Link to Item
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Cain, Elizabeth Hope, Ashirbani Saha, Michael R. Harowicz, Jeffrey R. Marks, P Kelly Marcom, and Maciej A. Mazurowski. “Multivariate machine learning models for prediction of pathologic response to neoadjuvant therapy in breast cancer using MRI features: a study using an independent validation set.” Breast Cancer Res Treat 173, no. 2 (January 2019): 455–63. https://doi.org/10.1007/s10549-018-4990-9.Full Text Link to Item
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Hou, R., Y. Ren, L. J. Grimm, M. A. Mazurowski, J. R. Marks, L. King, C. C. Maley, E. Shelley Hwang, and J. Y. Lo. “Malignant microcalcification clusters detection using unsupervised deep autoencoders.” Progress in Biomedical Optics and Imaging Proceedings of Spie 10950 (January 1, 2019). https://doi.org/10.1117/12.2512829.Full Text
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Sang, Ling-Jie, Huai-Qiang Ju, Guang-Ping Liu, Tian Tian, Guo-Lin Ma, Yun-Xin Lu, Ze-Xian Liu, et al. “LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling.” Mol Cell 72, no. 3 (November 1, 2018): 601. https://doi.org/10.1016/j.molcel.2018.10.024.Full Text Link to Item
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Saha, Ashirbani, Michael R. Harowicz, Elizabeth Hope Cain, Allison H. Hall, Eun-Sil Shelley Hwang, Jeffrey R. Marks, Paul Kelly Marcom, and Maciej A. Mazurowski. “Intra-tumor molecular heterogeneity in breast cancer: definitions of measures and association with distant recurrence-free survival.” Breast Cancer Res Treat 172, no. 1 (November 2018): 123–32. https://doi.org/10.1007/s10549-018-4879-7.Full Text Link to Item
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Wang, Yumeng, Xiaoyan Xu, Dejan Maglic, Michael T. Dill, Kamalika Mojumdar, Patrick Kwok-Shing Ng, Kang Jin Jeong, et al. “Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.” Cell Rep 25, no. 5 (October 30, 2018): 1304-1317.e5. https://doi.org/10.1016/j.celrep.2018.10.001.Full Text Link to Item
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Korkut, Anil, Sobia Zaidi, Rupa S. Kanchi, Shuyun Rao, Nancy R. Gough, Andre Schultz, Xubin Li, et al. “A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.” Cell Syst 7, no. 4 (October 24, 2018): 422-437.e7. https://doi.org/10.1016/j.cels.2018.08.010.Full Text Link to Item
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Sang, Ling-Jie, Huai-Qiang Ju, Guang-Ping Liu, Tian Tian, Guo-Lin Ma, Yun-Xin Lu, Ze-Xian Liu, et al. “LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling.” Mol Cell 72, no. 1 (October 4, 2018): 71-83.e7. https://doi.org/10.1016/j.molcel.2018.08.014.Full Text Link to Item
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Wu, Jie, Zerun Jiang, Chen Chen, Qingsong Hu, Ziyi Fu, Junjie Chen, Zhangding Wang, et al. “CircIRAK3 sponges miR-3607 to facilitate breast cancer metastasis.” Cancer Lett 430 (August 28, 2018): 179–92. https://doi.org/10.1016/j.canlet.2018.05.033.Full Text Link to Item
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Xing, Zhen, Yanyan Zhang, Ke Liang, Liang Yan, Yu Xiang, Chunlai Li, Qingsong Hu, et al. “Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer.” Cancer Res 78, no. 16 (August 15, 2018): 4524–32. https://doi.org/10.1158/0008-5472.CAN-17-0385.Full Text Link to Item
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Kahles, André, Kjong-Van Lehmann, Nora C. Toussaint, Matthias Hüser, Stefan G. Stark, Timo Sachsenberg, Oliver Stegle, et al. “Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.” Cancer Cell 34, no. 2 (August 13, 2018): 211-224.e6. https://doi.org/10.1016/j.ccell.2018.07.001.Full Text Link to Item
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Bailey, Matthew H., Collin Tokheim, Eduard Porta-Pardo, Sohini Sengupta, Denis Bertrand, Amila Weerasinghe, Antonio Colaprico, et al. “Comprehensive Characterization of Cancer Driver Genes and Mutations.” Cell 174, no. 4 (August 9, 2018): 1034–35. https://doi.org/10.1016/j.cell.2018.07.034.Full Text Link to Item
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Ricketts, Christopher J., Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, et al. “The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.” Cell Rep 23, no. 12 (June 19, 2018): 3698. https://doi.org/10.1016/j.celrep.2018.06.032.Full Text Link to Item
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Thorsson, Vésteinn, David L. Gibbs, Scott D. Brown, Denise Wolf, Dante S. Bortone, Tai-Hsien Ou Yang, Eduard Porta-Pardo, et al. “The Immune Landscape of Cancer.” Immunity 48, no. 4 (April 17, 2018): 812-830.e14. https://doi.org/10.1016/j.immuni.2018.03.023.Full Text Link to Item
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Berger, Ashton C., Anil Korkut, Rupa S. Kanchi, Apurva M. Hegde, Walter Lenoir, Wenbin Liu, Yuexin Liu, et al. “A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.” Cancer Cell 33, no. 4 (April 9, 2018): 690-705.e9. https://doi.org/10.1016/j.ccell.2018.03.014.Full Text Link to Item
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Liu, Yang, Nilay S. Sethi, Toshinori Hinoue, Barbara G. Schneider, Andrew D. Cherniack, Francisco Sanchez-Vega, Jose A. Seoane, et al. “Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.” Cancer Cell 33, no. 4 (April 9, 2018): 721-735.e8. https://doi.org/10.1016/j.ccell.2018.03.010.Full Text Link to Item
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Taylor, Alison M., Juliann Shih, Gavin Ha, Galen F. Gao, Xiaoyang Zhang, Ashton C. Berger, Steven E. Schumacher, et al. “Genomic and Functional Approaches to Understanding Cancer Aneuploidy.” Cancer Cell 33, no. 4 (April 9, 2018): 676-689.e3. https://doi.org/10.1016/j.ccell.2018.03.007.Full Text Link to Item
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Wang, Zehua, Bo Yang, Min Zhang, Weiwei Guo, Zhiyuan Wu, Yue Wang, Lin Jia, et al. “lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.” Cancer Cell 33, no. 4 (April 9, 2018): 706-720.e9. https://doi.org/10.1016/j.ccell.2018.03.006.Full Text Link to Item
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Bailey, Matthew H., Collin Tokheim, Eduard Porta-Pardo, Sohini Sengupta, Denis Bertrand, Amila Weerasinghe, Antonio Colaprico, et al. “Comprehensive Characterization of Cancer Driver Genes and Mutations.” Cell 173, no. 2 (April 5, 2018): 371-385.e18. https://doi.org/10.1016/j.cell.2018.02.060.Full Text Link to Item
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Chen, Han, Chunyan Li, Xinxin Peng, Zhicheng Zhou, John N. Weinstein, John N. Cancer Genome Atlas Research Network, and Han Liang. “A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.” Cell 173, no. 2 (April 5, 2018): 386-399.e12. https://doi.org/10.1016/j.cell.2018.03.027.Full Text Link to Item
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Ding, Li, Matthew H. Bailey, Eduard Porta-Pardo, Vesteinn Thorsson, Antonio Colaprico, Denis Bertrand, David L. Gibbs, et al. “Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.” Cell 173, no. 2 (April 5, 2018): 305-320.e10. https://doi.org/10.1016/j.cell.2018.03.033.Full Text Link to Item
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Hoadley, Katherine A., Christina Yau, Toshinori Hinoue, Denise M. Wolf, Alexander J. Lazar, Esther Drill, Ronglai Shen, et al. “Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.” Cell 173, no. 2 (April 5, 2018): 291-304.e6. https://doi.org/10.1016/j.cell.2018.03.022.Full Text Link to Item
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Huang, Kuan-Lin, R Jay Mashl, Yige Wu, Deborah I. Ritter, Jiayin Wang, Clara Oh, Marta Paczkowska, et al. “Pathogenic Germline Variants in 10,389 Adult Cancers.” Cell 173, no. 2 (April 5, 2018): 355-370.e14. https://doi.org/10.1016/j.cell.2018.03.039.Full Text Link to Item
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Liu, Jianfang, Tara Lichtenberg, Katherine A. Hoadley, Laila M. Poisson, Alexander J. Lazar, Andrew D. Cherniack, Albert J. Kovatich, et al. “An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.” Cell 173, no. 2 (April 5, 2018): 400-416.e11. https://doi.org/10.1016/j.cell.2018.02.052.Full Text Link to Item
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Malta, Tathiane M., Artem Sokolov, Andrew J. Gentles, Tomasz Burzykowski, Laila Poisson, John N. Weinstein, Bożena Kamińska, et al. “Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.” Cell 173, no. 2 (April 5, 2018): 338-354.e15. https://doi.org/10.1016/j.cell.2018.03.034.Full Text Link to Item
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Sanchez-Vega, Francisco, Marco Mina, Joshua Armenia, Walid K. Chatila, Augustin Luna, Konnor C. La, Sofia Dimitriadoy, et al. “Oncogenic Signaling Pathways in The Cancer Genome Atlas.” Cell 173, no. 2 (April 5, 2018): 321-337.e10. https://doi.org/10.1016/j.cell.2018.03.035.Full Text Link to Item
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Campbell, Joshua D., Christina Yau, Reanne Bowlby, Yuexin Liu, Kevin Brennan, Huihui Fan, Alison M. Taylor, et al. “Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.” Cell Rep 23, no. 1 (April 3, 2018): 194-212.e6. https://doi.org/10.1016/j.celrep.2018.03.063.Full Text Link to Item
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Chiu, Hua-Sheng, Sonal Somvanshi, Ektaben Patel, Ting-Wen Chen, Vivek P. Singh, Barry Zorman, Sagar L. Patil, et al. “Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context.” Cell Rep 23, no. 1 (April 3, 2018): 297-312.e12. https://doi.org/10.1016/j.celrep.2018.03.064.Full Text Link to Item
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Gao, Qingsong, Wen-Wei Liang, Steven M. Foltz, Gnanavel Mutharasu, Reyka G. Jayasinghe, Song Cao, Wen-Wei Liao, et al. “Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.” Cell Rep 23, no. 1 (April 3, 2018): 227-238.e3. https://doi.org/10.1016/j.celrep.2018.03.050.Full Text Link to Item
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Ge, Zhongqi, Jake S. Leighton, Yumeng Wang, Xinxin Peng, Zhongyuan Chen, Hu Chen, Yutong Sun, et al. “Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.” Cell Rep 23, no. 1 (April 3, 2018): 213-226.e3. https://doi.org/10.1016/j.celrep.2018.03.047.Full Text Link to Item
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Jayasinghe, Reyka G., Song Cao, Qingsong Gao, Michael C. Wendl, Nam Sy Vo, Sheila M. Reynolds, Yanyan Zhao, et al. “Systematic Analysis of Splice-Site-Creating Mutations in Cancer.” Cell Rep 23, no. 1 (April 3, 2018): 270-281.e3. https://doi.org/10.1016/j.celrep.2018.03.052.Full Text Link to Item
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Knijnenburg, Theo A., Linghua Wang, Michael T. Zimmermann, Nyasha Chambwe, Galen F. Gao, Andrew D. Cherniack, Huihui Fan, et al. “Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.” Cell Rep 23, no. 1 (April 3, 2018): 239-254.e6. https://doi.org/10.1016/j.celrep.2018.03.076.Full Text Link to Item
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Peng, Xinxin, Zhongyuan Chen, Farshad Farshidfar, Xiaoyan Xu, Philip L. Lorenzi, Yumeng Wang, Feixiong Cheng, et al. “Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers.” Cell Rep 23, no. 1 (April 3, 2018): 255-269.e4. https://doi.org/10.1016/j.celrep.2018.03.077.Full Text Link to Item
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Ricketts, Christopher J., Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, et al. “The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.” Cell Rep 23, no. 1 (April 3, 2018): 313-326.e5. https://doi.org/10.1016/j.celrep.2018.03.075.Full Text Link to Item
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Saltz, Joel, Rajarsi Gupta, Le Hou, Tahsin Kurc, Pankaj Singh, Vu Nguyen, Dimitris Samaras, et al. “Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.” Cell Rep 23, no. 1 (April 3, 2018): 181-193.e7. https://doi.org/10.1016/j.celrep.2018.03.086.Full Text Link to Item
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Seiler, Michael, Shouyong Peng, Anant A. Agrawal, James Palacino, Teng Teng, Ping Zhu, Peter G. Smith, Peter G. Cancer Genome Atlas Research Network, Silvia Buonamici, and Lihua Yu. “Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.” Cell Rep 23, no. 1 (April 3, 2018): 282-296.e4. https://doi.org/10.1016/j.celrep.2018.01.088.Full Text Link to Item
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Way, Gregory P., Francisco Sanchez-Vega, Konnor La, Joshua Armenia, Walid K. Chatila, Augustin Luna, Chris Sander, et al. “Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.” Cell Rep 23, no. 1 (April 3, 2018): 172-180.e3. https://doi.org/10.1016/j.celrep.2018.03.046.Full Text Link to Item
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Ellrott, Kyle, Matthew H. Bailey, Gordon Saksena, Kyle R. Covington, Cyriac Kandoth, Chip Stewart, Julian Hess, et al. “Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines.” Cell Syst 6, no. 3 (March 28, 2018): 271-281.e7. https://doi.org/10.1016/j.cels.2018.03.002.Full Text Link to Item
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Schaub, Franz X., Varsha Dhankani, Ashton C. Berger, Mihir Trivedi, Anne B. Richardson, Reid Shaw, Wei Zhao, et al. “Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.” Cell Syst 6, no. 3 (March 28, 2018): 282-300.e2. https://doi.org/10.1016/j.cels.2018.03.003.Full Text Link to Item
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Shi, Bibo, Lars J. Grimm, Maciej A. Mazurowski, Jay A. Baker, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, E Shelley Hwang, and Joseph Y. Lo. “Prediction of Occult Invasive Disease in Ductal Carcinoma in Situ Using Deep Learning Features.” J Am Coll Radiol 15, no. 3 Pt B (March 2018): 527–34. https://doi.org/10.1016/j.jacr.2017.11.036.Full Text Link to Item
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Wang, Shouyu, Ke Liang, Qingsong Hu, Ping Li, Jian Song, Yuedong Yang, Jun Yao, et al. “JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.” J Clin Invest 127, no. 12 (December 1, 2017): 4498–4515. https://doi.org/10.1172/JCI91553.Full Text Link to Item
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Zheng, Xin, Han Han, Guang-Ping Liu, Yan-Xiu Ma, Ruo-Lang Pan, Ling-Jie Sang, Rui-Hua Li, et al. “LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.” Embo J 36, no. 22 (November 15, 2017): 3325–35. https://doi.org/10.15252/embj.201797609.Full Text Link to Item
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Harowicz, Michael R., Ashirbani Saha, Lars J. Grimm, P Kelly Marcom, Jeffrey R. Marks, E Shelley Hwang, and Maciej A. Mazurowski. “Can algorithmically assessed MRI features predict which patients with a preoperative diagnosis of ductal carcinoma in situ are upstaged to invasive breast cancer?” J Magn Reson Imaging 46, no. 5 (November 2017): 1332–40. https://doi.org/10.1002/jmri.25655.Full Text Link to Item
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Shi, Bibo, Lars J. Grimm, Maciej A. Mazurowski, Jay A. Baker, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, E Shelley Hwang, and Joseph Y. Lo. “Can Occult Invasive Disease in Ductal Carcinoma In Situ Be Predicted Using Computer-extracted Mammographic Features?” Acad Radiol 24, no. 9 (September 2017): 1139–47. https://doi.org/10.1016/j.acra.2017.03.013.Full Text Link to Item
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Chen, Po-Han, Timothy J. Smith, Jianli Wu, Priscila F. Siesser, Brittany J. Bisnett, Farhan Khan, Maxwell Hogue, et al. “Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.” Embo J 36, no. 15 (August 1, 2017): 2233–50. https://doi.org/10.15252/embj.201696113.Full Text Open Access Copy Link to Item
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Lin, Aifu, Qingsong Hu, Chunlai Li, Zhen Xing, Guolin Ma, Cheng Wang, Jun Li, et al. “The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors.” Nat Cell Biol 19, no. 3 (March 2017): 238–51. https://doi.org/10.1038/ncb3473.Full Text Link to Item
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Harowicz, Michael R., Timothy J. Robinson, Michaela A. Dinan, Ashirbani Saha, Jeffrey R. Marks, P Kelly Marcom, and Maciej A. Mazurowski. “Algorithms for prediction of the Oncotype DX recurrence score using clinicopathologic data: a review and comparison using an independent dataset.” Breast Cancer Res Treat 162, no. 1 (February 2017): 1–10. https://doi.org/10.1007/s10549-016-4093-4.Full Text Link to Item
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Southey, Melissa C., David E. Goldgar, Robert Winqvist, Katri Pylkäs, Fergus Couch, Marc Tischkowitz, William D. Foulkes, et al. “PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.” J Med Genet 53, no. 12 (December 2016): 800–811. https://doi.org/10.1136/jmedgenet-2016-103839.Full Text Link to Item
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Adams, Daniel L., Diane K. Adams, R Katherine Alpaugh, Massimo Cristofanilli, Stuart S. Martin, Saranya Chumsri, Cha-Mei Tang, and Jeffrey R. Marks. “Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions.” Cancer Epidemiol Biomarkers Prev 25, no. 7 (July 2016): 1037–42. https://doi.org/10.1158/1055-9965.EPI-15-1221.Full Text Link to Item
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Ryser, Marc D., Mathias Worni, Elizabeth L. Turner, Jeffrey R. Marks, Rick Durrett, and E Shelley Hwang. “Outcomes of Active Surveillance for Ductal Carcinoma in Situ: A Computational Risk Analysis.” J Natl Cancer Inst 108, no. 5 (May 2016). https://doi.org/10.1093/jnci/djv372.Full Text Link to Item
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Piccolo, Stephen R., Laura M. Hoffman, Thomas Conner, Gajendra Shrestha, Adam L. Cohen, Jeffrey R. Marks, Leigh A. Neumayer, et al. “Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility.” Mol Syst Biol 12, no. 3 (March 10, 2016): 860. https://doi.org/10.15252/msb.20156506.Full Text Link to Item
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Lin, Aifu, Chunlai Li, Zhen Xing, Qingsong Hu, Ke Liang, Leng Han, Cheng Wang, et al. “The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.” Nat Cell Biol 18, no. 2 (February 2016): 213–24. https://doi.org/10.1038/ncb3295.Full Text Link to Item
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Lawrenson, Kate, Edwin S. Iversen, Jonathan Tyrer, Rachel Palmieri Weber, Patrick Concannon, Dennis J. Hazelett, Qiyuan Li, et al. “Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.” Carcinogenesis 36, no. 11 (November 2015): 1341–53. https://doi.org/10.1093/carcin/bgv138.Full Text Link to Item
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Ciriello, Giovanni, Michael L. Gatza, Andrew H. Beck, Matthew D. Wilkerson, Suhn K. Rhie, Alessandro Pastore, Hailei Zhang, et al. “Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer.” Cell 163, no. 2 (October 8, 2015): 506–19. https://doi.org/10.1016/j.cell.2015.09.033.Full Text Link to Item
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Elsarraj, Hanan S., Yan Hong, Kelli E. Valdez, Whitney Michaels, Marcus Hook, William P. Smith, Jeremy Chien, et al. “Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion.” Breast Cancer Res 17 (September 17, 2015): 128. https://doi.org/10.1186/s13058-015-0630-z.Full Text Link to Item
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Marks, Jeffrey R., Karen S. Anderson, Paul Engstrom, Andrew K. Godwin, Laura J. Esserman, Gary Longton, Edwin S. Iversen, Anu Mathew, Christos Patriotis, and Margaret S. Pepe. “Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.” Cancer Epidemiol Biomarkers Prev 24, no. 2 (February 2015): 435–41. https://doi.org/10.1158/1055-9965.EPI-14-1178.Full Text Link to Item
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Tang, Xiaohu, Chao-Chieh Lin, Ivan Spasojevic, Edwin S. Iversen, Jen-Tsan Chi, and Jeffrey R. Marks. “A joint analysis of metabolomics and genetics of breast cancer.” Breast Cancer Res 16, no. 4 (August 5, 2014): 415. https://doi.org/10.1186/s13058-014-0415-9.Full Text Link to Item
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Marks, Jeffrey R. “Refining the role of BRCA1 in combating oxidative stress.” Breast Cancer Res 15, no. 6 (December 5, 2013): 320. https://doi.org/10.1186/bcr3583.Full Text Link to Item
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Schildkraut, Joellen M., Edwin S. Iversen, Lucy Akushevich, Regina Whitaker, Rex C. Bentley, Andrew Berchuck, and Jeffrey R. Marks. “Molecular signatures of epithelial ovarian cancer: analysis of associations with tumor characteristics and epidemiologic risk factors.” Cancer Epidemiol Biomarkers Prev 22, no. 10 (October 2013): 1709–21. https://doi.org/10.1158/1055-9965.EPI-13-0192.Full Text Link to Item
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Grant, Delores J., Cathrine Hoyo, Lucy Akushevich, Edwin S. Iversen, Regina Whitaker, Jeffrey Marks, Andrew Berchuck, and Joellen M. Schildkraut. “Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American women.” Gynecol Oncol 129, no. 1 (April 2013): 173–78. https://doi.org/10.1016/j.ygyno.2012.12.027.Full Text Link to Item
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Jin, Hongjun, Don S. Daly, Jeffrey R. Marks, and Richard C. Zangar. “Oxidatively modified proteins as plasma biomarkers in breast cancer.” Cancer Biomark 13, no. 3 (2013): 193–200. https://doi.org/10.3233/CBM-130349.Full Text Link to Item
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Cancer Genome Atlas Network, Mark. “Comprehensive molecular portraits of human breast tumours.” Nature 490, no. 7418 (October 4, 2012): 61–70. https://doi.org/10.1038/nature11412.Full Text Link to Item
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Lowery, William J., Joellen M. Schildkraut, Liudmila Akushevich, Rex Bentley, Jeffrey R. Marks, David Huntsman, and Andrew Berchuck. “Loss of ARID1A-associated protein expression is a frequent event in clear cell and endometrioid ovarian cancers.” Int J Gynecol Cancer 22, no. 1 (January 2012): 9–14. https://doi.org/10.1097/IGC.0b013e318231f140.Full Text Link to Item
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Fackler, Mary Jo, Christopher B. Umbricht, Danielle Williams, Pedram Argani, Leigh-Ann Cruz, Vanessa F. Merino, Wei Wen Teo, et al. “Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence.” Cancer Res 71, no. 19 (October 1, 2011): 6195–6207. https://doi.org/10.1158/0008-5472.CAN-11-1630.Full Text Link to Item
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Kung, Hsiu-Ni, Jeffrey R. Marks, and Jen-Tsan Chi. “Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia.” Plos Genet 7, no. 8 (August 2011): e1002229. https://doi.org/10.1371/journal.pgen.1002229.Full Text Link to Item
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Wardell, Suzanne E., Jeffrey R. Marks, and Donald P. McDonnell. “The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy.” Biochem Pharmacol 82, no. 2 (July 15, 2011): 122–30. https://doi.org/10.1016/j.bcp.2011.03.031.Full Text Link to Item
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Gonzalez, Rachel M., Don S. Daly, Ruimin Tan, Jeffrey R. Marks, and Richard C. Zangar. “Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.” Cancer Epidemiol Biomarkers Prev 20, no. 7 (July 2011): 1543–51. https://doi.org/10.1158/1055-9965.EPI-10-1248.Full Text Link to Item
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Gatza, Michael L., Hsiu-Ni Kung, Kimberly L. Blackwell, Mark W. Dewhirst, Jeffrey R. Marks, and Jen-Tsan Chi. “Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes.” Breast Cancer Res 13, no. 3 (June 7, 2011): R62. https://doi.org/10.1186/bcr2899.Full Text Link to Item
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Koh, James, Moahad Dar, Brian R. Untch, Darshana Dixit, Yuhong Shi, Zhao Yang, Mohamed Abdelgadir Adam, et al. “Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor.” Mol Endocrinol 25, no. 5 (May 2011): 867–76. https://doi.org/10.1210/me.2010-0277.Full Text Link to Item
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Havrilesky, Laura J., Gillian D. Sanders, Shalini Kulasingam, Junzo P. Chino, Andrew Berchuck, Jeffrey R. Marks, and Evan R. Myers. “Development of an ovarian cancer screening decision model that incorporates disease heterogeneity: implications for potential mortality reduction.” Cancer 117, no. 3 (February 1, 2011): 545–53. https://doi.org/10.1002/cncr.25624.Full Text Link to Item
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Liggett, Thomas E., Anatoliy A. Melnikov, Jeffrey R. Marks, and Victor V. Levenson. “Methylation patterns in cell-free plasma DNA reflect removal of the primary tumor and drug treatment of breast cancer patients.” Int J Cancer 128, no. 2 (January 15, 2011): 492–99. https://doi.org/10.1002/ijc.25363.Full Text Link to Item
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Anderson, Karen S., Sahar Sibani, Garrick Wallstrom, Ji Qiu, Eliseo A. Mendoza, Jacob Raphael, Eugenie Hainsworth, et al. “Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer.” J Proteome Res 10, no. 1 (January 7, 2011): 85–96. https://doi.org/10.1021/pr100686b.Full Text Link to Item
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Il’yasova, Dora, Kelly Kennedy, Ivan Spasojevic, Frances Wang, Adviye A. Tolun, Karel Base, Sarah P. Young, et al. “Individual responses to chemotherapy-induced oxidative stress.” Breast Cancer Res Treat 125, no. 2 (January 2011): 583–89. https://doi.org/10.1007/s10549-010-1158-7.Full Text Link to Item
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Adam, Mohamed Abdelgadir, Brian R. Untch, Melissa E. Danko, Sandra Stinnett, Darshana Dixit, James Koh, Jeffrey R. Marks, and John A. Olson. “Severe obesity is associated with symptomatic presentation, higher parathyroid hormone levels, and increased gland weight in primary hyperparathyroidism.” J Clin Endocrinol Metab 95, no. 11 (November 2010): 4917–24. https://doi.org/10.1210/jc.2010-0666.Full Text Link to Item
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Moorman, Patricia G., Edwin S. Iversen, P Kelly Marcom, Jeffrey R. Marks, Frances Wang, Frances Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Eunjung Lee, et al. “Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis.” Breast Cancer Res Treat 124, no. 2 (November 2010): 441–51. https://doi.org/10.1007/s10549-010-0842-y.Full Text Link to Item
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Il’yasova, Dora, Ivan Spasojevic, Frances Wang, Adviye A. Tolun, Karel Base, Sarah P. Young, P Kelly Marcom, et al. “Urinary biomarkers of oxidative status in a clinical model of oxidative assault.” Cancer Epidemiol Biomarkers Prev 19, no. 6 (June 2010): 1506–10. https://doi.org/10.1158/1055-9965.EPI-10-0211.Full Text Link to Item
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Bernardini, Marcus Q., Tsukasa Baba, Paula S. Lee, Jason C. Barnett, Gregory P. Sfakianos, Angeles Alvarez Secord, Susan K. Murphy, Edwin Iversen, Jeffrey R. Marks, and Andrew Berchuck. “Expression signatures of TP53 mutations in serous ovarian cancers.” Bmc Cancer 10 (May 26, 2010): 237. https://doi.org/10.1186/1471-2407-10-237.Full Text Open Access Copy Link to Item
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Barry, William T., Dawn N. Kernagis, Holly K. Dressman, Ryan J. Griffis, J’vonne D. Hunter, John A. Olson, Jeff R. Marks, et al. “Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.” J Clin Oncol 28, no. 13 (May 1, 2010): 2198–2206. https://doi.org/10.1200/JCO.2009.26.7245.Full Text Link to Item
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Danko, Melissa E., Kyla M. Bennett, Jun Zhai, Jeffrey R. Marks, and John A. Olson. “Improved staging in node-positive breast cancer patients using lymph node ratio: results in 1,788 patients with long-term follow-up.” J Am Coll Surg 210, no. 5 (May 2010): 797–807. https://doi.org/10.1016/j.jamcollsurg.2010.02.045.Full Text Link to Item
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Yurkovetsky, Zoya, Steven Skates, Aleksey Lomakin, Brian Nolen, Trenton Pulsipher, Francesmary Modugno, Jeffrey Marks, et al. “Development of a multimarker assay for early detection of ovarian cancer.” J Clin Oncol 28, no. 13 (May 1, 2010): 2159–66. https://doi.org/10.1200/JCO.2008.19.2484.Full Text Link to Item
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Schildkraut, Joellen M., Edwin S. Iversen, Melanie A. Wilson, Merlise A. Clyde, Patricia G. Moorman, Rachel T. Palmieri, Regina Whitaker, Rex C. Bentley, Jeffrey R. Marks, and Andrew Berchuck. “Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.” Plos One 5, no. 4 (April 8, 2010): e10061. https://doi.org/10.1371/journal.pone.0010061.Full Text Open Access Copy Link to Item
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Barnett, Jason C., Sarah M. Bean, Regina S. Whitaker, Eiji Kondoh, Tsukasa Baba, Shingo Fujii, Jeffrey R. Marks, Holly K. Dressman, Susan K. Murphy, and Andrew Berchuck. “Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype.” Gynecol Oncol 116, no. 3 (March 2010): 556–62. https://doi.org/10.1016/j.ygyno.2009.11.020.Full Text Link to Item
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Hartman, Zachary C., Junping Wei, Takuya Osada, Oliver Glass, Gangjun Lei, Xiao-Yi Yang, Sharon Peplinski, et al. “An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity.” Clin Cancer Res 16, no. 5 (March 1, 2010): 1466–77. https://doi.org/10.1158/1078-0432.CCR-09-2549.Full Text Link to Item
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Phelan, Catherine M., Ya-Yu Tsai, Ellen L. Goode, Robert A. Vierkant, Brooke L. Fridley, Jonathan Beesley, Xiao Qing Chen, et al. “Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium.” Cancer Epidemiol Biomarkers Prev 19, no. 2 (February 2010): 600–604. https://doi.org/10.1158/1055-9965.EPI-09-0861.Full Text Link to Item
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Hoyo, Cathrine, Joellen M. Schildkraut, Susan K. Murphy, Wong-Ho Chow, Thomas L. Vaughan, Harvey Risch, Jeffrey R. Marks, et al. “IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.” Int J Cancer 125, no. 11 (December 1, 2009): 2673–78. https://doi.org/10.1002/ijc.24623.Full Text Link to Item
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Tebbit, Christopher L., Jun Zhai, Brian R. Untch, Matthew J. Ellis, Holly K. Dressman, Rex C. Bentley, Jay A. Baker, et al. “Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care.” Breast Cancer Res Treat 118, no. 3 (December 2009): 635–43. https://doi.org/10.1007/s10549-008-0301-1.Full Text Link to Item
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Il’yasova, Dora, Gabriel Mixon, Frances Wang, P Kelly Marcom, Jeffrey Marks, Ivan Spasojevich, Neal Craft, Francisco Arredondo, and Richard DiGiulio. “Markers of oxidative status in a clinical model of oxidative assault: a pilot study in human blood following doxorubicin administration.” Biomarkers 14, no. 5 (August 2009): 321–25. https://doi.org/10.1080/13547500902946757.Full Text Link to Item
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Hoyo, Cathrine, Janet Grubber, Wendy Demark-Wahnefried, Bruce Lobaugh, Amy S. Jeffreys, Steven C. Grambow, Jeffrey R. Marks, Temitope O. Keku, Phillip J. Walther, and Joellen M. Schildkraut. “Predictors of variation in serum IGF1 and IGFBP3 levels in healthy African American and white men.” J Natl Med Assoc 101, no. 7 (July 2009): 711–16. https://doi.org/10.1016/s0027-9684(15)30981-0.Full Text Link to Item
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Westmoreland, Tammy J., Sajith M. Wickramasekara, Andrew Y. Guo, Alice L. Selim, Tiffany S. Winsor, Arno L. Greenleaf, Kimberly L. Blackwell, John A. Olson, Jeffrey R. Marks, and Craig B. Bennett. “Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae.” Plos One 4, no. 6 (June 8, 2009): e5830. https://doi.org/10.1371/journal.pone.0005830.Full Text Link to Item
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Jesneck, Jonathan L., Sayan Mukherjee, Zoya Yurkovetsky, Merlise Clyde, Jeffrey R. Marks, Anna E. Lokshin, and Joseph Y. Lo. “Do serum biomarkers really measure breast cancer?” Bmc Cancer 9 (May 28, 2009): 164. https://doi.org/10.1186/1471-2407-9-164.Full Text Link to Item
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Levina, Vera, Brian M. Nolen, Adele M. Marrangoni, Peng Cheng, Jeffrey R. Marks, Miroslaw J. Szczepanski, Marta E. Szajnik, Elieser Gorelik, and Anna E. Lokshin. “Role of eotaxin-1 signaling in ovarian cancer.” Clin Cancer Res 15, no. 8 (April 15, 2009): 2647–56. https://doi.org/10.1158/1078-0432.CCR-08-2024.Full Text Link to Item
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Berchuck, Andrew, Edwin S. Iversen, Jingqin Luo, Jennifer P. Clarke, Hisani Horne, Douglas A. Levine, Jeff Boyd, et al. “Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome.” Clin Cancer Res 15, no. 7 (April 1, 2009): 2448–55. https://doi.org/10.1158/1078-0432.CCR-08-2430.Full Text Link to Item
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Schildkraut, Joellen M., Ellen L. Goode, Merlise A. Clyde, Edwin S. Iversen, Patricia G. Moorman, Andrew Berchuck, Jeffrey R. Marks, et al. “Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.” Cancer Res 69, no. 6 (March 15, 2009): 2349–57. https://doi.org/10.1158/0008-5472.CAN-08-2902.Full Text Link to Item
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Horne, Hisani N., Paula S. Lee, Susan K. Murphy, Miguel A. Alonso, John A. Olson, and Jeffrey R. Marks. “Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy.” Mol Cancer Res 7, no. 2 (February 2009): 199–209. https://doi.org/10.1158/1541-7786.MCR-08-0314.Full Text Link to Item
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Baba, T., P. A. Convery, N. Matsumura, R. S. Whitaker, E. Kondoh, T. Perry, Z. Huang, et al. “Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells.” Oncogene 28, no. 2 (January 15, 2009): 209–18. https://doi.org/10.1038/onc.2008.374.Full Text Link to Item
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Hardee, Matthew E., Rose J. Eapen, Zahid N. Rabbani, Matthew R. Dreher, Jeffrey Marks, Kimberly L. Blackwell, and Mark W. Dewhirst. “Her2/neu signaling blockade improves tumor oxygenation in a multifactorial fashion in Her2/neu+ tumors.” Cancer Chemother Pharmacol 63, no. 2 (January 2009): 219–28. https://doi.org/10.1007/s00280-008-0729-3.Full Text Link to Item
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Anders, Carey K., David S. Hsu, Gloria Broadwater, Chaitanya R. Acharya, John A. Foekens, Yi Zhang, Yixin Wang, et al. “Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression.” J Clin Oncol 26, no. 20 (July 10, 2008): 3324–30. https://doi.org/10.1200/JCO.2007.14.2471.Full Text Link to Item
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Desai, Shyamal D., Laurence M. Wood, Yu-Chen Tsai, Tao-Shih Hsieh, Jeffrey R. Marks, Georgia L. Scott, Beppino C. Giovanella, and Leroy F. Liu. “ISG15 as a novel tumor biomarker for drug sensitivity.” Mol Cancer Ther 7, no. 6 (June 2008): 1430–39. https://doi.org/10.1158/1535-7163.MCT-07-2345.Full Text Link to Item
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Schildkraut, Joellen M., Patricia G. Moorman, Amy E. Bland, Susan Halabi, Brian Calingaert, Regina Whitaker, Paula S. Lee, et al. “Cyclin E overexpression in epithelial ovarian cancer characterizes an etiologic subgroup.” Cancer Epidemiol Biomarkers Prev 17, no. 3 (March 2008): 585–93. https://doi.org/10.1158/1055-9965.EPI-07-0596.Full Text Link to Item
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Bennett, Craig B., Tammy J. Westmoreland, Carmel S. Verrier, Carrie A. B. Blanchette, Tiffany L. Sabin, Hemali P. Phatnani, Yuliya V. Mishina, et al. “Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.” Plos One 3, no. 1 (January 16, 2008): e1448. https://doi.org/10.1371/journal.pone.0001448.Full Text Open Access Copy Link to Item
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Anders, Carey K., Chaitanya R. Acharya, David S. Hsu, Gloria Broadwater, Katherine Garman, John A. Foekens, Yi Zhang, et al. “Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.” Plos One 3, no. 1 (January 2, 2008): e1373. https://doi.org/10.1371/journal.pone.0001373.Full Text Open Access Copy Link to Item
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Nolen, Brian M., Jeffrey R. Marks, Shlomo Ta’san, Alex Rand, The Minh Luong, Yun Wang, Kimberly Blackwell, and Anna E. Lokshin. “Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer.” Breast Cancer Res 10, no. 3 (2008): R45. https://doi.org/10.1186/bcr2096.Full Text Link to Item
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Hoyo, Cathrine, Janet Grubber, Wendy Demark-Wahnefried, Jeffrey R. Marks, Stephen J. Freedland, Amy S. Jeffreys, Steven C. Grambow, Robert M. Wenham, Philip J. Walther, and Joellen M. Schildkraut. “Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whites.” J Natl Med Assoc 99, no. 7 (July 2007): 718–22.Link to Item
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Spillman, Monique A., Judith Lacy, Susan K. Murphy, Regina S. Whitaker, Lisa Grace, Vanessa Teaberry, Jeffrey R. Marks, and Andrew Berchuck. “Regulation of the metastasis suppressor gene MKK4 in ovarian cancer.” Gynecol Oncol 105, no. 2 (May 2007): 312–20. https://doi.org/10.1016/j.ygyno.2006.12.017.Full Text Link to Item
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Gayther, Simon A., Honglin Song, Susan J. Ramus, Susan Krüger Kjaer, Alice S. Whittemore, Lydia Quaye, Jonathan Tyrer, et al. “Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.” Cancer Res 67, no. 7 (April 1, 2007): 3027–35. https://doi.org/10.1158/0008-5472.CAN-06-3261.Full Text Link to Item
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Huper, Gudrun, and Jeffrey R. Marks. “Isogenic normal basal and luminal mammary epithelial isolated by a novel method show a differential response to ionizing radiation.” Cancer Res 67, no. 7 (April 1, 2007): 2990–3001. https://doi.org/10.1158/0008-5472.CAN-06-4065.Full Text Link to Item
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Schildkraut, Joellen M., Susan K. Murphy, Rachel T. Palmieri, Edwin Iversen, Patricia G. Moorman, Zhiqing Huang, Susan Halabi, et al. “Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer.” Cancer Epidemiol Biomarkers Prev 16, no. 3 (March 2007): 473–80. https://doi.org/10.1158/1055-9965.EPI-06-0868.Full Text Link to Item
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Skates, Steven J., Nora K. Horick, Joseph M. Moy, Anna M. Minihan, Michael V. Seiden, Jeffrey R. Marks, Patrick Sluss, and Daniel W. Cramer. “Pooling of case specimens to create standard serum sets for screening cancer biomarkers.” Cancer Epidemiol Biomarkers Prev 16, no. 2 (February 2007): 334–41. https://doi.org/10.1158/1055-9965.EPI-06-0681.Full Text Link to Item
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Dong, Mei, Tam How, Kellye C. Kirkbride, Kelly J. Gordon, Jason D. Lee, Nadine Hempel, Patrick Kelly, Benjamin J. Moeller, Jeffrey R. Marks, and Gerard C. Blobe. “The type III TGF-beta receptor suppresses breast cancer progression.” J Clin Invest 117, no. 1 (January 2007): 206–17. https://doi.org/10.1172/JCI29293.Full Text Link to Item
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Gynecologic Oncology Group, Andrew, Angeles Alvarez Secord, Paula S. Lee, Kathleen M. Darcy, Laura J. Havrilesky, Lisa A. Grace, Jeffrey R. Marks, and Andrew Berchuck. “Maspin expression in epithelial ovarian cancer and associations with poor prognosis: a Gynecologic Oncology Group study.” Gynecol Oncol 101, no. 3 (June 2006): 390–97. https://doi.org/10.1016/j.ygyno.2006.02.014.Full Text Link to Item
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Brown, Nicholas M., Timothy T. Stenzel, Paula N. Friedman, Jerry Henslee, Gudrun Huper, and Jeffrey R. Marks. “Evaluation of expression based markers for the detection of breast cancer cells.” Breast Cancer Res Treat 97, no. 1 (May 2006): 41–47. https://doi.org/10.1007/s10549-005-9085-8.Full Text Link to Item
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Yao, Jun, Stanislawa Weremowicz, Bin Feng, Robert C. Gentleman, Jeffrey R. Marks, Rebecca Gelman, Cameron Brennan, and Kornelia Polyak. “Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression.” Cancer Res 66, no. 8 (April 15, 2006): 4065–78. https://doi.org/10.1158/0008-5472.CAN-05-4083.Full Text Link to Item
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Murphy, Susan K., Zhiqing Huang, Yaqing Wen, Monique A. Spillman, Regina S. Whitaker, Lauren R. Simel, Teresa D. Nichols, Jeffrey R. Marks, and Andrew Berchuck. “Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer.” Mol Cancer Res 4, no. 4 (April 2006): 283–92. https://doi.org/10.1158/1541-7786.MCR-05-0138.Full Text Link to Item
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Schafer, Zachary T., Amanda B. Parrish, Kevin M. Wright, Seth S. Margolis, Jeffrey R. Marks, Mohanish Deshmukh, and Sally Kornbluth. “Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells.” Cancer Res 66, no. 4 (February 15, 2006): 2210–18. https://doi.org/10.1158/0008-5472.CAN-05-3923.Full Text Link to Item
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Dressman, Holly K., Christopher Hans, Andrea Bild, John A. Olson, Eric Rosen, P Kelly Marcom, Vlayka B. Liotcheva, et al. “Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy.” Clin Cancer Res 12, no. 3 Pt 1 (February 1, 2006): 819–26. https://doi.org/10.1158/1078-0432.CCR-05-1447.Full Text Link to Item
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Bild, Andrea H., Guang Yao, Jeffrey T. Chang, Quanli Wang, Anil Potti, Dawn Chasse, Mary-Beth Joshi, et al. “Oncogenic pathway signatures in human cancers as a guide to targeted therapies.” Nature 439, no. 7074 (January 19, 2006): 353–57. https://doi.org/10.1038/nature04296.Full Text Link to Item
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Huang, Zhiqing, Yaqing Wen, Ruby Shandilya, Jeffrey R. Marks, Andrew Berchuck, and Susan K. Murphy. “High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer.” Nucleic Acids Res 34, no. 2 (2006): 555–63. https://doi.org/10.1093/nar/gkj468.Full Text Link to Item
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Lancaster, J. M., H. K. Dressman, J. P. Clarke, R. A. Sayer, M. A. Martino, J. M. Cragun, A. H. Henriott, et al. “Identification of genes associated with ovarian cancer metastasis using microarray expression analysis.” Int J Gynecol Cancer 16, no. 5 (2006): 1733–45. https://doi.org/10.1111/j.1525-1438.2006.00660.x.Full Text Link to Item
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Lancaster, J. M., R. A. Sayer, C. Blanchette, B. Calingaert, I. Konidari, J. Gray, J. Schildkraut, D. W. Schomberg, J. R. Marks, and A. Berchuck. “High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated preoperative serum levels.” Int J Gynecol Cancer 16, no. 4 (2006): 1529–35. https://doi.org/10.1111/j.1525-1438.2006.00623.x.Full Text Link to Item
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Schildkraut, Joellen M., Patricia G. Moorman, Susan Halabi, Brian Calingaert, Jeffrey R. Marks, and Andrew Berchuck. “Analgesic drug use and risk of ovarian cancer.” Epidemiology 17, no. 1 (January 2006): 104–7. https://doi.org/10.1097/01.ede.0000190538.55645.f8.Full Text Link to Item
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Petros, William P., Penelope J. Hopkins, Susan Spruill, Gloria Broadwater, James J. Vredenburgh, O Michael Colvin, William P. Peters, Roy B. Jones, Jeff Hall, and Jeffrey R. Marks. “Associations between drug metabolism genotype, chemotherapy pharmacokinetics, and overall survival in patients with breast cancer.” J Clin Oncol 23, no. 25 (September 1, 2005): 6117–25. https://doi.org/10.1200/JCO.2005.06.075.Full Text Link to Item
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Berchuck, Andrew, Edwin S. Iversen, Johnathan M. Lancaster, Jennifer Pittman, Jingqin Luo, Paula Lee, Susan Murphy, et al. “Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers.” Clin Cancer Res 11, no. 10 (May 15, 2005): 3686–96. https://doi.org/10.1158/1078-0432.CCR-04-2398.Full Text Link to Item
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Spillman, Monique A., Joellen M. Schildkraut, Susan Halabi, Patricia Moorman, Brian Calingaert, Rex C. Bentley, Jeffrey R. Marks, Susan Murphy, and Andrew Berchuck. “Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk.” Gynecol Oncol 97, no. 2 (May 2005): 543–49. https://doi.org/10.1016/j.ygyno.2005.01.025.Full Text Link to Item
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Wang, Wei, Gudrun Huper, Yueqi Guo, Susan K. Murphy, John A. Olson, and Jeffrey R. Marks. “Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.” Oncogene 24, no. 16 (April 14, 2005): 2705–14. https://doi.org/10.1038/sj.onc.1208464.Full Text Link to Item
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Sayer, Robyn A., Johnathan M. Lancaster, Jennifer Pittman, Jonathon Gray, Regina Whitaker, Jeffrey R. Marks, and Andrew Berchuck. “High insulin-like growth factor-2 (IGF-2) gene expression is an independent predictor of poor survival for patients with advanced stage serous epithelial ovarian cancer.” Gynecol Oncol 96, no. 2 (February 2005): 355–61. https://doi.org/10.1016/j.ygyno.2004.10.012.Full Text Link to Item
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Schildkraut, Joellen M., Wendy Demark-Wahnefried, Robert M. Wenham, Janet Grubber, Amy S. Jeffreys, Steven C. Grambow, Jeffrey R. Marks, et al. “IGF1 (CA)19 repeat and IGFBP3 -202 A/C genotypes and the risk of prostate cancer in Black and White men.” Cancer Epidemiol Biomarkers Prev 14, no. 2 (February 2005): 403–8. https://doi.org/10.1158/1055-9965.EPI-04-0426.Full Text Link to Item
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Berchuck, Andrew, Joellen M. Schildkraut, Robert M. Wenham, Brian Calingaert, Shazia Ali, Amy Henriott, Susan Halabi, et al. “Progesterone receptor promoter +331A polymorphism is associated with a reduced risk of endometrioid and clear cell ovarian cancers.” Cancer Epidemiol Biomarkers Prev 13, no. 12 (December 2004): 2141–47.Link to Item
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Wang, Wei, Rita Nahta, Gudrun Huper, and Jeffrey R. Marks. “TAFII70 isoform-specific growth suppression correlates with its ability to complex with the GADD45a protein.” Mol Cancer Res 2, no. 8 (August 2004): 442–52.Link to Item
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Ochiai, Hidenobu, Stephanie A. Moore, Gary E. Archer, Tatsunori Okamura, Tracy A. Chewning, Jeffrey R. Marks, John H. Sampson, and Matthias Gromeier. “Treatment of intracerebral neoplasia and neoplastic meningitis with regional delivery of oncolytic recombinant poliovirus.” Clin Cancer Res 10, no. 14 (July 15, 2004): 4831–38. https://doi.org/10.1158/1078-0432.CCR-03-0694.Full Text Link to Item
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Shao, Rong, Shideng Bao, Xuefang Bai, Carrie Blanchette, Ryan M. Anderson, Tongyun Dang, Mikhail L. Gishizky, Jeffrey R. Marks, and Xiao-Fan Wang. “Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.” Mol Cell Biol 24, no. 9 (May 2004): 3992–4003. https://doi.org/10.1128/MCB.24.9.3992-4003.2004.Full Text Link to Item
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Tebbit, Christopher L., Rex C. Bentley, John A. Olson, and Jeffrey R. Marks. “Estrogen receptor alpha (ESR1) mutant A908G is not a common feature in benign and malignant proliferations of the breast.” Genes Chromosomes Cancer 40, no. 1 (May 2004): 51–54. https://doi.org/10.1002/gcc.20017.Full Text Link to Item
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Westmoreland, Tammy J., Jeffrey R. Marks, John A. Olson, Eric M. Thompson, Michael A. Resnick, and Craig B. Bennett. “Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae.” Eukaryot Cell 3, no. 2 (April 2004): 430–46. https://doi.org/10.1128/EC.3.2.430-446.2004.Full Text Link to Item
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Berchuck, Andrew, Edwin S. Iversen, Johnathan M. Lancaster, Holly K. Dressman, Mike West, Joseph R. Nevins, and Jeffrey R. Marks. “Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays.” Am J Obstet Gynecol 190, no. 4 (April 2004): 910–25. https://doi.org/10.1016/j.ajog.2004.02.005.Full Text Link to Item
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Lancaster, Johnathan M., Holly K. Dressman, Regina S. Whitaker, Laura Havrilesky, Jonathan Gray, Jeffrey R. Marks, Joseph R. Nevins, and Andrew Berchuck. “Gene expression patterns that characterize advanced stage serous ovarian cancers.” J Soc Gynecol Investig 11, no. 1 (January 2004): 51–59. https://doi.org/10.1016/j.jsgi.2003.07.004.Full Text Link to Item
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Wenham, Robert M., Joellen M. Schildkraut, Kia McLean, Brian Calingaert, Rex C. Bentley, Jeffrey Marks, and Andrew Berchuck. “Polymorphisms in BRCA1 and BRCA2 and risk of epithelial ovarian cancer.” Clin Cancer Res 9, no. 12 (October 1, 2003): 4396–4403.Link to Item
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Porter, Dale, Stanislawa Weremowicz, Koei Chin, Pankaj Seth, Aparna Keshaviah, Jaana Lahti-Domenici, Young Kyung Bae, et al. “A neural survival factor is a candidate oncogene in breast cancer.” Proc Natl Acad Sci U S A 100, no. 19 (September 16, 2003): 10931–36. https://doi.org/10.1073/pnas.1932980100.Full Text Link to Item
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Ellis, Matthew J., Eric Rosen, Holly Dressman, and Jeffery Marks. “Neoadjuvant comparisons of aromatase inhibitors and tamoxifen: pretreatment determinants of response and on-treatment effect.” J Steroid Biochem Mol Biol 86, no. 3–5 (September 2003): 301–7. https://doi.org/10.1016/s0960-0760(03)00371-6.Full Text Link to Item
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Wenham, Robert M., Brian Calingaert, Shazia Ali, Kia McClean, Regina Whitaker, Rex Bentley, Johnathan M. Lancaster, Joellen Schildkraut, Jeffrey Marks, and Andrew Berchuck. “Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer.” J Soc Gynecol Investig 10, no. 6 (September 2003): 381–87. https://doi.org/10.1016/s1071-5576(03)00141-2.Full Text Link to Item
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Westmoreland, T. J., J. A. Olson, W. Y. Saito, G. Huper, J. R. Marks, and C. B. Bennett. “Dhh1 regulates the G1/S-checkpoint following DNA damage or BRCA1 expression in yeast.” J Surg Res 113, no. 1 (July 2003): 62–73. https://doi.org/10.1016/s0022-4804(03)00155-0.Full Text Link to Item
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Lancaster, Johnathan M., Robert M. Wenham, Susan Halabi, Brian Calingaert, Jeffrey R. Marks, Patricia G. Moorman, Rex C. Bentley, Andrew Berchuck, and Joellen M. Schildkraut. “No relationship between ovarian cancer risk and progesterone receptor gene polymorphism in a population-based, case-control study in North Carolina.” Cancer Epidemiol Biomarkers Prev 12, no. 3 (March 2003): 226–27.Link to Item
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Mu, David, Liyun Chen, Xiping Zhang, Lei-Hoon See, Christina M. Koch, Clifford Yen, James Jiayuan Tong, et al. “Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene.” Cancer Cell 3, no. 3 (March 2003): 297–302. https://doi.org/10.1016/s1535-6108(03)00054-0.Full Text Link to Item
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Porter, Dale, Jaana Lahti-Domenici, Aparna Keshaviah, Young Kyung Bae, Pedram Argani, Jeffrey Marks, Andrea Richardson, et al. “Molecular markers in ductal carcinoma in situ of the breast.” Mol Cancer Res 1, no. 5 (March 2003): 362–75.Link to Item
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Lancaster, Johnathan M., Robyn Sayer, Carrie Blanchette, Brian Calingaert, Regina Whitaker, Joellen Schildkraut, Jeffrey Marks, and Andrew Berchuck. “High expression of tumor necrosis factor-related apoptosis-inducing ligand is associated with favorable ovarian cancer survival.” Clin Cancer Res 9, no. 2 (February 2003): 762–66.Link to Item
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Gilliam, Lisa K., Edward K. Lobenhofer, Paula K. Greer, Richard M. Scearce, Frank D. Cirisano, Jeffrey R. Marks, and Laura P. Hale. “BRCA2 monoclonal antibodies react with differentiating epithelium.” Hybrid Hybridomics 21, no. 4 (August 2002): 261–69. https://doi.org/10.1089/153685902760213877.Full Text Link to Item
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Li, Jing, Ying Yang, Yue Peng, Richard J. Austin, Winfried G. van Eyndhoven, Ken C. Q. Nguyen, Tim Gabriele, et al. “Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.” Nat Genet 31, no. 2 (June 2002): 133–34. https://doi.org/10.1038/ng888.Full Text Link to Item
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Spang, Rainer, Harry Zuzan, Mike West, Joseph Nevins, Carrie Blanchette, and Jeffrey R. Marks. “Prediction and uncertainty in the analysis of gene expression profiles.” In Silico Biol 2, no. 3 (2002): 369–81.Link to Item
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Havrilesky, L. J., A. A. Alvarez, R. S. Whitaker, J. R. Marks, and A. Berchuck. “Loss of expression of the p16 tumor suppressor gene is more frequent in advanced ovarian cancers lacking p53 mutations.” Gynecol Oncol 83, no. 3 (December 2001): 491–500. https://doi.org/10.1006/gyno.2001.6464.Full Text Link to Item
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West, M., C. Blanchette, H. Dressman, E. Huang, S. Ishida, R. Spang, H. Zuzan, J. A. Olson, J. R. Marks, and J. R. Nevins. “Predicting the clinical status of human breast cancer by using gene expression profiles.” Proc Natl Acad Sci U S A 98, no. 20 (September 25, 2001): 11462–67. https://doi.org/10.1073/pnas.201162998.Full Text Link to Item
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Krop, I. E., D. Sgroi, D. A. Porter, K. L. Lunetta, R. LeVangie, P. Seth, C. M. Kaelin, et al. “HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells.” Proc Natl Acad Sci U S A 98, no. 17 (August 14, 2001): 9796–9801. https://doi.org/10.1073/pnas.171138398.Full Text Link to Item
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Porter, D. A., I. E. Krop, S. Nasser, D. Sgroi, C. M. Kaelin, J. R. Marks, G. Riggins, and K. Polyak. “A SAGE (serial analysis of gene expression) view of breast tumor progression.” Cancer Res 61, no. 15 (August 1, 2001): 5697–5702.Link to Item
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Moorman, P. G., A. Hamza, J. R. Marks, and J. A. Olson. “Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma.” Cancer 91, no. 12 (June 15, 2001): 2258–62.Link to Item
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Umbricht, C. B., E. Evron, E. Gabrielson, A. Ferguson, J. Marks, and S. Sukumar. “Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.” Oncogene 20, no. 26 (June 7, 2001): 3348–53. https://doi.org/10.1038/sj.onc.1204438.Full Text Link to Item
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Evron, E., C. B. Umbricht, D. Korz, V. Raman, D. M. Loeb, B. Niranjan, L. Buluwela, S. A. Weitzman, J. Marks, and S. Sukumar. “Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation.” Cancer Res 61, no. 6 (March 15, 2001): 2782–87.Link to Item
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Havrilesky, L. J., C. P. McMahon, E. K. Lobenhofer, R. Whitaker, J. R. Marks, and A. Berchuck. “Relationship between expression of coactivators and corepressors of hormone receptors and resistance of ovarian cancers to growth regulation by steroid hormones.” J Soc Gynecol Investig 8, no. 2 (2001): 104–13.Link to Item
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Seth, P., K. L. Lunetta, D. W. Bell, H. Gray, S. M. Nasser, E. Rhei, C. M. Kaelin, et al. “Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer.” Cancer Res 60, no. 24 (December 15, 2000): 6859–63.Link to Item
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Lobenhofer, E. K., and J. R. Marks. “Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity.” J Steroid Biochem Mol Biol 75, no. 1 (December 1, 2000): 11–20. https://doi.org/10.1016/s0960-0760(00)00132-1.Full Text Link to Item
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Raman, V., S. A. Martensen, D. Reisman, E. Evron, W. F. Odenwald, E. Jaffee, J. Marks, and S. Sukumar. “Compromised HOXA5 function can limit p53 expression in human breast tumours.” Nature 405, no. 6789 (June 22, 2000): 974–78. https://doi.org/10.1038/35016125.Full Text Link to Item
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Ferguson, A. T., E. Evron, C. B. Umbricht, T. K. Pandita, T. A. Chan, H. Hermeking, J. R. Marks, et al. “High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.” Proc Natl Acad Sci U S A 97, no. 11 (May 23, 2000): 6049–54. https://doi.org/10.1073/pnas.100566997.Full Text Link to Item
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Lobenhofer, E. K., G. Huper, J. D. Iglehart, and J. R. Marks. “Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis.” Cell Growth Differ 11, no. 2 (February 2000): 99–110.Link to Item
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Davis, P. L., A. Miron, L. M. Andersen, J. D. Iglehart, and J. R. Marks. “Isolation and initial characterization of the BRCA2 promoter.” Oncogene 18, no. 44 (October 28, 1999): 6000–6012. https://doi.org/10.1038/sj.onc.1202990.Full Text Link to Item
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Carey, L. A., N. W. Kim, S. Goodman, J. Marks, G. Henderson, C. B. Umbricht, J. S. Dome, W. Dooley, S. R. Amshey, and S. Sukumar. “Telomerase activity and prognosis in primary breast cancers.” J Clin Oncol 17, no. 10 (October 1999): 3075–81. https://doi.org/10.1200/JCO.1999.17.10.3075.Full Text Link to Item
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Lambers, A. R., C. Gumbs, S. Ali, J. R. Marks, J. D. Iglehart, A. Berchuck, and P. A. Futreal. “Bcl10 is not a target for frequent mutation in human carcinomas.” Br J Cancer 80, no. 10 (July 1999): 1575–76. https://doi.org/10.1038/sj.bjc.6690564.Full Text Link to Item
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Umbricht, C. B., M. E. Sherman, J. Dome, L. A. Carey, J. Marks, N. Kim, and S. Sukumar. “Telomerase activity in ductal carcinoma in situ and invasive breast cancer.” Oncogene 18, no. 22 (June 3, 1999): 3407–14. https://doi.org/10.1038/sj.onc.1202714.Full Text Link to Item
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Szukala, S. A., J. R. Marks, J. L. Burchette, A. A. Elbendary, and H. R. Krigman. “Co-expression of p53 by epithelial and stromal elements in carcinosarcoma of the female genital tract: an immunohistochemical study of 19 cases.” Int J Gynecol Cancer 9, no. 2 (March 1999): 131–36. https://doi.org/10.1046/j.1525-1438.1999.09905.x.Full Text Link to Item
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Dong, Q., S. P. Johnson, O. M. Colvin, N. Bullock, C. Kilborn, G. Runyon, D. M. Sullivan, et al. “Multiple DNA repair mechanisms and alkylator resistance in the human medulloblastoma cell line D-283 Med (4-HCR).” Cancer Chemother Pharmacol 43, no. 1 (1999): 73–79. https://doi.org/10.1007/s002800050865.Full Text Link to Item
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Lopez, C. B., T. D. Rao, H. Feiner, R. Shapiro, J. R. Marks, and A. B. Frey. “Repression of interleukin-2 mRNA translation in primary human breast carcinoma tumor-infiltrating lymphocytes.” Cell Immunol 190, no. 2 (December 15, 1998): 141–55. https://doi.org/10.1006/cimm.1998.1390.Full Text Link to Item
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Berchuck, A., K. A. Heron, M. E. Carney, J. M. Lancaster, E. G. Fraser, V. L. Vinson, A. M. Deffenbaugh, et al. “Frequency of germline and somatic BRCA1 mutations in ovarian cancer.” Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 4, no. 10 (October 1998): 2433–37.
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Berchuck, A., M. Carney, J. M. Lancaster, J. Marks, and A. P. Futreal. “Familial breast-ovarian cancer syndromes: BRCA1 and BRCA2.” Clin Obstet Gynecol 41, no. 1 (March 1998): 157–66. https://doi.org/10.1097/00003081-199803000-00022.Full Text Link to Item
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Burke, H. B., A. Hoang, J. D. Iglehart, and J. R. Marks. “Predicting response to adjuvant and radiation therapy in patients with early stage breast carcinoma.” Cancer 82, no. 5 (March 1, 1998): 874–77. https://doi.org/10.1002/(sici)1097-0142(19980301)82:5<874::aid-cncr11>3.0.co;2-y.Full Text Link to Item
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Carney, M. E., G. L. Maxwell, J. M. Lancaster, C. Gumbs, J. Marks, A. Berchuck, and P. A. Futreal. “Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers.” J Soc Gynecol Investig 5, no. 5 (1998): 281–85. https://doi.org/10.1016/s1071-5576(98)00018-5.Full Text Link to Item
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Davis, P. L., W. L. Shaiu, G. L. Scott, J. D. Iglehart, T. S. Hsieh, and J. R. Marks. “Complex response of breast epithelial cell lines to topoisomerase inhibitors.” Anticancer Res 18, no. 4C (1998): 2919–32.Link to Item
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Peters, K. G., A. Coogan, D. Berry, J. Marks, J. D. Iglehart, C. D. Kontos, P. Rao, S. Sankar, and E. Trogan. “Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis.” Br J Cancer 77, no. 1 (1998): 51–56. https://doi.org/10.1038/bjc.1998.8.Full Text Link to Item
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Burke, H. B., P. H. Goodman, D. B. Rosen, D. E. Henson, J. N. Weinstein, F. E. Harrell, J. R. Marks, D. P. Winchester, and D. G. Bostwick. “Artificial neural networks improve the accuracy of cancer survival prediction.” Cancer 79, no. 4 (February 15, 1997): 857–62. https://doi.org/10.1002/(sici)1097-0142(19970215)79:4<857::aid-cncr24>3.0.co;2-y.Full Text Link to Item
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Marks, J. R., G. Huper, J. P. Vaughn, P. L. Davis, J. Norris, D. P. McDonnell, R. W. Wiseman, P. A. Futreal, and J. D. Iglehart. “BRCA1 expression is not directly responsive to estrogen.” Oncogene 14, no. 1 (January 9, 1997): 115–21. https://doi.org/10.1038/sj.onc.1200808.Full Text Link to Item
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Vaughn, J. P., J. Stekler, S. Demirdji, J. K. Mills, M. H. Caruthers, J. D. Iglehart, and J. R. Marks. “Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides.” Nucleic Acids Res 24, no. 22 (November 15, 1996): 4558–64. https://doi.org/10.1093/nar/24.22.4558.Full Text Link to Item
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Kohler, M. F., P. Carney, R. Dodge, J. T. Soper, D. L. Clarke-Pearson, J. R. Marks, and A. Berchuck. “p53 overexpression in advanced-stage endometrial adenocarcinoma.” Am J Obstet Gynecol 175, no. 5 (November 1996): 1246–52. https://doi.org/10.1016/s0002-9378(96)70036-4.Full Text Link to Item
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Lancaster, J. M., H. A. Brownlee, D. A. Bell, P. A. Futreal, J. R. Marks, A. Berchuck, R. W. Wiseman, and J. A. Taylor. “Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer.” Mol Carcinog 17, no. 3 (November 1996): 160–62. https://doi.org/10.1002/(SICI)1098-2744(199611)17:3<160::AID-MC8>3.0.CO;2-J.Full Text Link to Item
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Hettasch, J. M., N. Bandarenko, J. L. Burchette, T. S. Lai, J. R. Marks, Z. A. Haroon, K. Peters, M. W. Dewhirst, J. D. Iglehart, and C. S. Greenberg. “Tissue transglutaminase expression in human breast cancer.” Lab Invest 75, no. 5 (November 1996): 637–45.Link to Item
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Vaughn, J. P., F. D. Cirisano, G. Huper, A. Berchuck, P. A. Futreal, J. R. Marks, and J. D. Iglehart. “Cell cycle control of BRCA2.” Cancer Res 56, no. 20 (October 15, 1996): 4590–94.Link to Item
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Davis, P., K. Bazar, G. Huper, G. Lozano, J. Marks, and J. D. Iglehart. “Dominance of wild-type p53-mediated transcriptional activation in breast epithelial cells.” Oncogene 13, no. 6 (September 19, 1996): 1315–22.Link to Item
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Elbendary, A. A., F. D. Cirisano, A. C. Evans, P. L. Davis, J. D. Iglehart, J. R. Marks, and A. Berchuck. “Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells.” Clin Cancer Res 2, no. 9 (September 1996): 1571–75.Link to Item
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Lancaster, J. M., R. Wooster, J. Mangion, C. M. Phelan, C. Cochran, C. Gumbs, S. Seal, et al. “BRCA2 mutations in primary breast and ovarian cancers.” Nat Genet 13, no. 2 (June 1996): 238–40. https://doi.org/10.1038/ng0696-238.Full Text Link to Item
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Vaughn, J. P., P. L. Davis, M. D. Jarboe, G. Huper, A. C. Evans, R. W. Wiseman, A. Berchuck, J. D. Iglehart, P. A. Futreal, and J. R. Marks. “BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.” Cell Growth Differ 7, no. 6 (June 1996): 711–15.Link to Item
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Hankins, G. R., A. T. De Souza, R. C. Bentley, M. R. Patel, J. R. Marks, J. D. Iglehart, and R. L. Jirtle. “M6P/IGF2 receptor: a candidate breast tumor suppressor gene.” Oncogene 12, no. 9 (May 2, 1996): 2003–9.Link to Item
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Norris, J., D. Fan, C. Aleman, J. R. Marks, P. A. Futreal, R. W. Wiseman, J. D. Iglehart, P. L. Deininger, and D. P. McDonnell. “Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers.” J Biol Chem 270, no. 39 (September 29, 1995): 22777–82. https://doi.org/10.1074/jbc.270.39.22777.Full Text Link to Item
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Vaughn, J. P., J. D. Iglehart, S. Demirdji, P. Davis, L. E. Babiss, M. H. Caruthers, and J. R. Marks. “Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.” Proc Natl Acad Sci U S A 92, no. 18 (August 29, 1995): 8338–42. https://doi.org/10.1073/pnas.92.18.8338.Full Text Link to Item
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Harpole, D. H., J. R. Marks, W. G. Richards, J. E. Herndon, and D. J. Sugarbaker. “Localized adenocarcinoma of the lung: oncogene expression of erbB-2 and p53 in 150 patients.” Clin Cancer Res 1, no. 6 (June 1995): 659–64.Link to Item
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Iglehart, J. D., B. J. Kerns, G. Huper, and J. R. Marks. “Maintenance of DNA content and erbB-2 alterations in intraductal and invasive phases of mammary cancer.” Breast Cancer Res Treat 34, no. 3 (June 1995): 253–63. https://doi.org/10.1007/BF00689717.Full Text Link to Item
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Layfield, L. J., B. M. Kerns, D. H. Conlon, J. D. Iglehart, J. R. Marks, and R. K. Dodge. “Determination of Proliferation Index By MIB‐1 Immunostaining in Early Stage Breast Cancer Using Quantitative Image Analysis.” The Breast Journal 1, no. 6 (January 1, 1995): 362–71. https://doi.org/10.1111/j.1524-4741.1995.tb00263.x.Full Text
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Harpole, D. H., J. E. Herndon, W. G. Wolfe, J. D. Iglehart, and J. R. Marks. “A prognostic model of recurrence and death in stage I non-small cell lung cancer utilizing presentation, histopathology, and oncoprotein expression.” Cancer Res 55, no. 1 (January 1, 1995): 51–56.Link to Item
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Krigman, H. R., A. C. Coogan, and J. R. Marks. “Simultaneous endometrial malignant mixed mesodermal tumor and ovarian serous adenocarcinoma.” Arch Pathol Lab Med 119, no. 1 (January 1995): 99–103.Link to Item
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Elbendary, A., A. Berchuck, P. Davis, L. Havrilesky, R. C. Bast, J. D. Iglehart, and J. R. Marks. “Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells.” Cell Growth Differ 5, no. 12 (December 1994): 1301–7.Link to Item
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Futreal, P. A., Q. Liu, D. Shattuck-Eidens, C. Cochran, K. Harshman, S. Tavtigian, L. M. Bennett, A. Haugen-Strano, J. Swensen, and Y. Miki. “BRCA1 mutations in primary breast and ovarian carcinomas.” Science 266, no. 5182 (October 7, 1994): 120–22. https://doi.org/10.1126/science.7939630.Full Text Link to Item
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Kamb, A., P. A. Futreal, J. Rosenthal, C. Cochran, K. D. Harshman, Q. Liu, R. S. Phelps, S. V. Tavtigian, T. Tran, and C. Hussey. “Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1.” Genomics 23, no. 1 (September 1, 1994): 163–67. https://doi.org/10.1006/geno.1994.1473.Full Text Link to Item
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Futreal, P. A., C. Cochran, J. Rosenthal, Y. Miki, J. Swenson, M. Hobbs, L. M. Bennett, A. Haugen-Strano, J. Marks, and J. C. Barrett. “Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture.” Hum Mol Genet 3, no. 8 (August 1994): 1359–64. https://doi.org/10.1093/hmg/3.8.1359.Full Text Link to Item
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Pykett, M. J., M. E. Murphy, P. R. Harnish, M. Muenke, J. Marks, and D. L. George. “Loss of chromosome 8p sequences in human breast carcinoma cell lines.” Cancer Genet Cytogenet 76, no. 1 (August 1994): 23–28. https://doi.org/10.1016/0165-4608(94)90064-7.Full Text Link to Item
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Futreal, P. A., C. Cochran, J. R. Marks, J. D. Iglehart, W. Zimmerman, J. C. Barrett, and R. W. Wiseman. “Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.” Cancer Res 54, no. 7 (April 1, 1994): 1791–94.Link to Item
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Marks, J. R., P. A. Humphrey, K. Wu, D. Berry, N. Bandarenko, B. J. Kerns, and J. D. Iglehart. “Overexpression of p53 and HER-2/neu proteins as prognostic markers in early stage breast cancer.” Ann Surg 219, no. 4 (April 1994): 332–41. https://doi.org/10.1097/00000658-199404000-00002.Full Text Link to Item
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HUMPHREY, P. A., D. W. FRANQUEMONT, W. A. GEARY, B. J. M. KERNS, J. D. IGLEHART, and J. R. MARKS. “IMMUNODETECTION OF P53 PROTEIN IN NONINVASIVE EPITHELIAL PROLIFERATIVE BREAST DISEASE.” Applied Immunohistochemistry 2, no. 1 (March 1, 1994): 22–28.Link to Item
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Lightner, V. A., J. R. Marks, and S. S. McCachren. “Epithelial cells are an important source of tenascin in normal and malignant human breast tissue.” Exp Cell Res 210, no. 2 (February 1994): 177–84. https://doi.org/10.1006/excr.1994.1027.Full Text Link to Item
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Liu, F. S., M. F. Kohler, J. R. Marks, R. C. Bast, J. Boyd, and A. Berchuck. “Mutation and overexpression of the p53 tumor suppressor gene frequently occurs in uterine and ovarian sarcomas.” Obstet Gynecol 83, no. 1 (January 1994): 118–24.Link to Item
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Kerns, B. J., P. A. Jordan, G. Huper, J. R. Marks, J. D. Iglehart, and L. J. Layfied. “Assessment of c-erbB-2 amplification by immunohistochemistry in paraffin-embedded breast cancer.” Mod Pathol 6, no. 6 (November 1993): 673–78.Link to Item
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Kohler, M. F., J. R. Marks, R. W. Wiseman, I. J. Jacobs, A. M. Davidoff, D. L. Clarke-Pearson, J. T. Soper, R. C. Bast, and A. Berchuck. “Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer.” J Natl Cancer Inst 85, no. 18 (September 15, 1993): 1513–19. https://doi.org/10.1093/jnci/85.18.1513.Full Text Link to Item
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Kohler, M. F., H. Nishii, P. A. Humphrey, H. Saski, J. Marks, R. C. Bast, D. L. Clarke-Pearson, J. Boyd, and A. Berchuck. “Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias.” Am J Obstet Gynecol 169, no. 3 (September 1993): 690–94. https://doi.org/10.1016/0002-9378(93)90644-x.Full Text Link to Item
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Lidor, Y. J., F. J. Xu, O. Martínez-Maza, G. J. Olt, J. R. Marks, A. Berchuck, S. Ramakrishnan, J. S. Berek, and R. C. Bast. “Constitutive production of macrophage colony-stimulating factor and interleukin-6 by human ovarian surface epithelial cells.” Exp Cell Res 207, no. 2 (August 1993): 332–39. https://doi.org/10.1006/excr.1993.1200.Full Text Link to Item
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Kohler, M. F., B. J. Kerns, P. A. Humphrey, J. R. Marks, R. C. Bast, and A. Berchuck. “Mutation and overexpression of p53 in early-stage epithelial ovarian cancer.” Obstet Gynecol 81, no. 5 ( Pt 1) (May 1993): 643–50.Link to Item
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Jacobs, I. J., M. F. Kohler, R. W. Wiseman, J. R. Marks, R. Whitaker, B. A. Kerns, P. Humphrey, A. Berchuck, B. A. Ponder, and R. C. Bast. “Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation.” J Natl Cancer Inst 84, no. 23 (December 2, 1992): 1793–98. https://doi.org/10.1093/jnci/84.23.1793.Full Text Link to Item
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Boente, M. P., A. Berchuck, G. C. Rodriguez, A. Davidoff, R. Whitaker, F. J. Xu, J. Marks, D. L. Clarke-Pearson, and R. C. Bast. “The effect of interferon gamma on epidermal growth factor receptor expression in normal and malignant ovarian epithelial cells.” Am J Obstet Gynecol 167, no. 6 (December 1992): 1877–82. https://doi.org/10.1016/0002-9378(92)91790-h.Full Text Link to Item
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Kerns, B. J., P. A. Jordan, M. B. Moore, P. A. Humphrey, A. Berchuck, M. F. Kohler, R. C. Bast, J. D. Iglehart, and J. R. Marks. “p53 overexpression in formalin-fixed, paraffin-embedded tissue detected by immunohistochemistry.” J Histochem Cytochem 40, no. 7 (July 1992): 1047–51. https://doi.org/10.1177/40.7.1607637.Full Text Link to Item
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Futreal, P. A., P. Söderkvist, J. R. Marks, J. D. Iglehart, C. Cochran, J. C. Barrett, and R. W. Wiseman. “Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms.” Cancer Res 52, no. 9 (May 1, 1992): 2624–27.Link to Item
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Davidoff, A. M., J. D. Iglehart, and J. R. Marks. “Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.” Proc Natl Acad Sci U S A 89, no. 8 (April 15, 1992): 3439–42. https://doi.org/10.1073/pnas.89.8.3439.Full Text Link to Item
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Kohler, M. F., A. Berchuck, A. M. Davidoff, P. A. Humphrey, R. K. Dodge, J. D. Iglehart, J. T. Soper, D. L. Clarke-Pearson, R. C. Bast, and J. R. Marks. “Overexpression and mutation of p53 in endometrial carcinoma.” Cancer Res 52, no. 6 (March 15, 1992): 1622–27.Link to Item
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Davidoff, A. M., J. C. Pence, N. A. Shorter, J. D. Iglehart, and J. R. Marks. “Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines.” Oncogene 7, no. 1 (January 1992): 127–33.Link to Item
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Davidoff, A. M., B. J. Kerns, J. C. Pence, J. R. Marks, and J. D. Iglehart. “p53 alterations in all stages of breast cancer.” J Surg Oncol 48, no. 4 (December 1991): 260–67. https://doi.org/10.1002/jso.2930480409.Full Text Link to Item
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Pence, J. C., A. M. Kizilbash, B. J. Kerns, J. R. Marks, and J. D. Iglehart. “Proliferation index in various stages of breast cancer determined by Ki-67 immunostaining.” J Surg Oncol 48, no. 1 (September 1991): 11–20. https://doi.org/10.1002/jso.2930480104.Full Text Link to Item
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Davidoff, A. M., J. E. Herndon, N. S. Glover, B. J. Kerns, J. C. Pence, J. D. Iglehart, and J. R. Marks. “Relation between p53 overexpression and established prognostic factors in breast cancer.” Surgery 110, no. 2 (August 1991): 259–64.Link to Item
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Marks, J. R., A. M. Davidoff, B. J. Kerns, P. A. Humphrey, J. C. Pence, R. K. Dodge, D. L. Clarke-Pearson, J. D. Iglehart, R. C. Bast, and A. Berchuck. “Overexpression and mutation of p53 in epithelial ovarian cancer.” Cancer Res 51, no. 11 (June 1, 1991): 2979–84.Link to Item
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Davidoff, A. M., P. A. Humphrey, J. D. Iglehart, and J. R. Marks. “Genetic basis for p53 overexpression in human breast cancer.” Proc Natl Acad Sci U S A 88, no. 11 (June 1, 1991): 5006–10. https://doi.org/10.1073/pnas.88.11.5006.Full Text Link to Item
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Davidoff, A. M., B. J. Kerns, J. D. Iglehart, and J. R. Marks. “Maintenance of p53 alterations throughout breast cancer progression.” Cancer Res 51, no. 10 (May 15, 1991): 2605–10.Link to Item
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Davidoff, A. M., J. C. Pence, B. J. M. Kerns, J. D. Iglehart, N. A. Shorter, and J. R. Marks. “P53 expression in neuroblastoma.” Surgical Forum 41 (December 1, 1990): 579–81.
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Iglehart, J. D., M. H. Kraus, B. C. Langton, G. Huper, B. J. Kerns, and J. R. Marks. “Increased erbB-2 gene copies and expression in multiple stages of breast cancer.” Cancer Res 50, no. 20 (October 15, 1990): 6701–7.Link to Item
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Cho, H. J., M. Seiberg, I. Georgoff, A. K. Teresky, J. R. Marks, and A. J. Levine. “Impact of the genetic background of transgenic mice upon the formation and timing of choroid plexus papillomas.” J Neurosci Res 24, no. 1 (September 1989): 115–22. https://doi.org/10.1002/jnr.490240116.Full Text Link to Item
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Marks, J. R., J. Lin, P. Hinds, D. Miller, and A. J. Levine. “Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen.” J Virol 63, no. 2 (February 1989): 790–97. https://doi.org/10.1128/JVI.63.2.790-797.1989.Full Text Link to Item
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Marks, J. R., and D. H. Spector. “Replication of the murine cytomegalovirus genome: structure and role of the termini in the generation and cleavage of concatenates.” Virology 162, no. 1 (January 1988): 98–107. https://doi.org/10.1016/0042-6822(88)90398-4.Full Text Link to Item
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Van Dyke, T. A., C. Finlay, D. Miller, J. Marks, G. Lozano, and A. J. Levine. “Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice.” J Virol 61, no. 6 (June 1987): 2029–32. https://doi.org/10.1128/JVI.61.6.2029-2032.1987.Full Text Link to Item
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Marks, J. R., and D. H. Spector. “Fusion of the termini of the murine cytomegalovirus genome after infection.” J Virol 52, no. 1 (October 1984): 24–28. https://doi.org/10.1128/JVI.52.1.24-28.1984.Full Text Link to Item
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Marks, J. R., J. A. Mercer, and D. H. Spector. “Transcription in mouse embryo cells permissively infected by murine cytomegalovirus.” Virology 131, no. 1 (November 1983): 247–54. https://doi.org/10.1016/0042-6822(83)90550-0.Full Text Link to Item
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Mercer, J. A., J. R. Marks, and D. H. Spector. “Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith Strain).” Virology 129, no. 1 (August 1983): 94–106. https://doi.org/10.1016/0042-6822(83)90398-7.Full Text Link to Item
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Book Sections
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Jesneck, J. L., S. Mukherjee, L. W. Nolte, A. E. Lokshin, J. R. Marks, and J. Lo. “Decision fusion of circulating markers for breast cancer detection in premenopausal women,” 1434–38, 2007. https://doi.org/10.1109/BIBE.2007.4375762.Full Text
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Marks, J., J. Lin, D. Miller, G. Lozano, J. Herbert, and A. J. Levine. “The expression of viral and cellular genes in papillomas of the choroid plexus induced in transgenic mice.,” 284:163–86, 1988.Link to Item
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Other Articles
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“Retraction. An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.” J Clin Oncol, February 20, 2012. https://doi.org/10.1200/jco.2012.42.0331.Full Text Link to Item
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Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Retraction: Genomic signatures to guide the use of chemotherapeutics.” Nat Med, January 2011. https://doi.org/10.1038/nm0111-135.Full Text Link to Item
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Hoyo, C., J. M. Schildkraut, S. K. Murph, W. H. Chow, T. L. Vaughan, H. Risch, J. R. Marks, et al. “IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas (International Journal of Cancer (2009) 125, (2673-2678)).” International Journal of Cancer, February 1, 2010. https://doi.org/10.1002/ijc.24975.Full Text
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300)).” Nature Medicine, August 1, 2008. https://doi.org/10.1038/nm0808-889.Full Text
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300)).” Nature Medicine, November 1, 2007. https://doi.org/10.1038/nm1107-1388.Full Text
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Dressman, Holly K., Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, et al. “An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.” J Clin Oncol, February 10, 2007. https://doi.org/10.1200/JCO.2006.06.3743.Full Text Link to Item
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Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Genomic signatures to guide the use of chemotherapeutics.” Nat Med, November 2006. https://doi.org/10.1038/nm1491.Full Text Link to Item
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Andrew, B., E. S. Iversen, J. M. Lancaster, H. K. Dressman, M. West, J. R. Nevins, J. R. Marks, and B. E. Miller. “Prediction of optimal versus suboptimal cytoreduction of advanced-stage serious ovarian cancer with the use of microarrays.” Women’S Oncology Review, September 1, 2004. https://doi.org/10.1080/14733400412331312585.Full Text
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Berchuck, A., G. L. Maxwell, and J. R. Marks. “Relationship between alterations in the p53 gene and chemosensitivity of ovarian cancers.” Cme Journal of Gynecologic Oncology, December 1, 1999.
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Conference Papers
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Hagos, Y. B., F. Sobhani, S. P. Castillo, A. H. Hall, K. AbdulJabbar, R. Salgado, B. Harmon, et al. “DCIS AI-TIL: Ductal Carcinoma In Situ Tumour Infiltrating Lymphocyte Scoring Using Artificial Intelligence.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 13602 LNCS:164–75, 2022. https://doi.org/10.1007/978-3-031-19660-7_16.Full Text
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Sobhani, F., A. Hamidinekoo, A. H. Hall, L. King, J. R. Marks, C. Maley, H. M. Horlings, E. Shelley Hwang, and Y. Yuan. “Automated Dcis Identification From Multiplex Immunohistochemistry Using Generative Adversarial Networks.” In Proceedings International Symposium on Biomedical Imaging, Vol. 2022-March, 2022. https://doi.org/10.1109/ISBI52829.2022.9761413.Full Text
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Narayanan, P. L., S. E. A. Raza, A. H. Hall, J. R. Marks, L. King, R. B. West, L. Hernandez, et al. “Unmasking the immune microecology of ductal carcinoma in situ with deep learning.” In Npj Breast Cancer, Vol. 7, 2021. https://doi.org/10.1038/s41523-020-00205-5.Full Text
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Ren, Y., J. Lu, Z. Liang, L. J. Grimm, C. Kim, M. Taylor-Cho, S. Yoon, J. R. Marks, and J. Y. Lo. “Retina-Match: Ipsilateral Mammography Lesion Matching in a Single Shot Detection Pipeline.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 12905 LNCS:345–54, 2021. https://doi.org/10.1007/978-3-030-87240-3_33.Full Text
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Angel, Peggi M., Janet Saunders, Heather Jensen-Smith, Evelyn Bruner, Marvella E. Ford, Savanna Berkhiser, Baylye Boxall, et al. “Abstract P2-10-18: Deciphering racial disparities in breast cancer collagen reorganization by targeted extracellular matrix proteomics.” In Cancer Research, Vol. 80. American Association for Cancer Research (AACR), 2020. https://doi.org/10.1158/1538-7445.sabcs19-p2-10-18.Full Text
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Rosenberg, Shoshana M., Laura H. Hendrix, Kristin L. Schreiber, Alastair M. Thompson, Isabelle Bedrosian, Kevin S. Hughes, Thomas Lynch, et al. “Abstract P1-21-07: The Patient-reported Outcomes after Routine Treatment of Atypical Lesions (PORTAL) study: Pain, psychosocial wellbeing, and quality of life among women undergoing guideline concordant care for DCIS vs. active surveillance for in situ and atypical lesions.” In Cancer Research, Vol. 80. American Association for Cancer Research (AACR), 2020. https://doi.org/10.1158/1538-7445.sabcs19-p1-21-07.Full Text
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Hou, R., L. J. Grimm, M. A. Mazurowski, J. R. Marks, L. M. King, C. C. Maley, E. S. Hwang, and J. Y. Lo. “A multitask deep learning method in simultaneously predicting occult invasive disease in ductal carcinoma in-situ and segmenting microcalcifications in mammography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11314, 2020. https://doi.org/10.1117/12.2549669.Full Text
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Peng, Y., R. Hou, Y. Ren, L. J. Grimm, J. R. Marks, E. S. Hwang, and J. Y. Lo. “Microcalcification localization and cluster detection using unsupervised convolutional autoencoders and structural similarity index.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11314, 2020. https://doi.org/10.1117/12.2551263.Full Text
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Fortunato, A., D. Mallo, L. King, T. Hardman, A. Hall, J. R. Marks, S. Hwang, and C. C. Maley. “Abstract P3-06-12: Genetic heterogeneity of DCIS is a predictor of invasive cancer.” In Cancer Research, Vol. 79. American Association for Cancer Research (AACR), 2019. https://doi.org/10.1158/1538-7445.sabcs18-p3-06-12.Full Text
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Kong, D., Y. Ren, R. Hou, L. J. Grimm, J. R. Marks, and J. Y. Lo. “Synthesis and texture manipulation of screening mammograms using conditional generative adversarial network.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10950, 2019. https://doi.org/10.1117/12.2513125.Full Text
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Ren, Y., R. Hou, D. Kong, Y. Geng, L. J. Grimm, J. R. Marks, and J. Y. Lo. “Multiview mammographic mass detection based on a single shot detection system.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10950, 2019. https://doi.org/10.1117/12.2513136.Full Text
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Ren, Y., Z. Zhu, Y. Li, D. Kong, R. Hou, L. J. Grimm, J. R. Marks, and J. Y. Lo. “Mask Embedding for Realistic High-Resolution Medical Image Synthesis.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 11769 LNCS:422–30, 2019. https://doi.org/10.1007/978-3-030-32226-7_47.Full Text
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Salas, Lucas A., Lauren C. Peres, Sarah E. Abbott, Casey S. Greene, Jeffrey R. Marks, Anthony J. Alberg, Elisa V. Bandera, et al. “Abstract 5318: High-grade serous ovarian cancer DNA methylation and survival in African-American women.” In Cancer Research, 78:5318–5318. American Association for Cancer Research (AACR), 2018. https://doi.org/10.1158/1538-7445.am2018-5318.Full Text
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Ryser, Marc D., Donald L. Weaver, Jeffrey R. Marks, Terry Hyslop, and E Shelley Hwang. “Quantifying the natural history and overtreatment rate of ductal carcinoma in situ.” In Cancer Research, Vol. 78. AMER ASSOC CANCER RESEARCH, 2018.Link to Item
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Lo, Joseph Y., Lars J. Grimm, Maciej A. Mazurowski, Jay A. Baker, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, Eun-Sil Shelley Hwang, and Bibo Shi. “Prediction of occult invasive disease in ductal carcinoma in situ using deep learning features.” In Cancer Research, Vol. 78. AMER ASSOC CANCER RESEARCH, 2018.Link to Item
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Hou, R., B. Shi, L. J. Grimm, M. A. Mazurowski, J. R. Marks, L. M. King, C. C. Maley, E. Shelley Hwang, and J. Y. Lo. “Improving classification with forced labeling of other related classes: Application to prediction of upstaged ductal carcinoma in situ using mammographic features.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10575, 2018. https://doi.org/10.1117/12.2293809.Full Text
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Shi, B., R. Hou, M. A. Mazurowski, L. J. Grimm, Y. Ren, J. R. Marks, L. M. King, C. C. Maley, E. S. Hwang, and J. Y. Lo. “Learning better deep features for the prediction of occult invasive disease in ductal carcinoma in situ through transfer learning.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10575, 2018. https://doi.org/10.1117/12.2293594.Full Text
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Ding, Y., J. R. Marks, L. M. King, A. H. Hall, E. R. Mardis, A. G. Rodrigo, C. C. Maley, and E. -. S. Hwang. “Abstract P1-06-06: Evidence for tumor heterogeneity and clonal evolution during invasive progression of breast cancer.” In Cancer Research, Vol. 77. American Association for Cancer Research (AACR), 2017. https://doi.org/10.1158/1538-7445.sabcs16-p1-06-06.Full Text
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Fortunato, A., L. King, D. Mallo, V. Kovacheva, Y. Yuan, A. Boddy, T. Graham, et al. “Abstract P1-05-30: Genomic and microenvironmental intra-tumor heterogeneity in DCIS.” In Cancer Research, Vol. 77. American Association for Cancer Research (AACR), 2017. https://doi.org/10.1158/1538-7445.sabcs16-p1-05-30.Full Text
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Harowicz, M. R., J. R. Marks, P. Kelly Marcom, and M. A. Mazurowski. “Can BI-RADS features on mammography be used as a surrogate for expensive genomic testing in breast cancer patients?” In Proceedings of Spie the International Society for Optical Engineering, Vol. 10327, 2017.
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Harowicz, M. R., J. R. Marks, P. Kelly Marcom, and M. A. Mazurowski. “Can BI-RADS features on mammography be used as a surrogate for expensive genomic testing in breast cancer patients?” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10136, 2017. https://doi.org/10.1117/12.2255866.Full Text
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Shi, B., L. J. Grimm, M. A. Mazurowski, J. R. Marks, L. M. King, C. C. Maley, E. S. Hwang, and J. Y. Lo. “Prediction of occult invasive disease in ductal carcinoma in situ using computer-extracted mammographic features.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10134, 2017. https://doi.org/10.1117/12.2255731.Full Text
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Shi, B., L. J. Grimm, M. A. Mazurowski, J. R. Marks, L. M. King, C. C. Maley, E. S. Hwang, and J. Y. Lo. “Can upstaging of ductal carcinoma in situ be predicted at biopsy by histologic and mammographic features?” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10134, 2017. https://doi.org/10.1117/12.2255847.Full Text
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Doherty, Jennifer A., Casey S. Greene, James E. Rudd, Laura J. Tafe, Anthony J. Alberg, Elisa V. Bandera, Jill Barnholtz-Sloan, et al. “Abstract 3407: Gene expression subtypes of high grade serous ovarian cancer in African American women.” In Cancer Research, 76:3407–3407. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.am2016-3407.Full Text
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Adams, Daniel L., Diane K. Adams, R Katherine Alpaugh, Massimo Cristofanilli, Stuart S. Martin, Saranya Chumsri, Cha-Mei Tang, and Jeffrey R. Marks. “Circulating cancer associated macrophage-like cells in the detection of invasive breast cancer.” In Journal of Clinical Oncology, 34:e23055–e23055. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.e23055.Full Text
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Das Roy, L., R. Zhou, L. Dillon, L. J. Moore, R. Puri, J. R. Marks, H. K. Lyerly, and P. Mukherjee. “Abstract P4-09-16: A monoclonal antibody with exceptional specificity across major breast cancer subtypes.” In Cancer Research, Vol. 76. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.sabcs15-p4-09-16.Full Text
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King, L. M., J. R. Marks, A. H. Hall, D. Temko, T. A. Graham, E. R. Mardis, C. C. Maley, and E. Hwang. “Abstract P6-05-03: Genomic diversity of ductal carcinoma in situ (DCIS) as a driver of invasion and metastasis.” In Cancer Research, Vol. 76. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.sabcs15-p6-05-03.Full Text
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Das Roy, Lopamudra, Ru Zhou, Laura Jeffords Moore, Lloye M. Dillon, Rahul Puri, Kim Lyerly, Jeffrey R. Marks, and Pinku Mukherjee. “Early detection of breast cancer using a unique tumor specific antibody.” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.Link to Item
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Adams, Daniel, Katherine Alpaugh, Massimo Cristofanilli, Stuart Martin, Saranya Chumsri, Raymond C. Bergen, Susan Tsai, et al. “Cancer associated macrophage-like cells as a blood-based biomarker for the screening of solid tumors.” In Cancer Research, Vol. 75, 2015. https://doi.org/10.1158/1538-7445.AM2015-5165.Full Text Link to Item
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Kung, Hsiu-Ni, Jeffrey R. Marks, and Jen-tsan Ashley Chi. “Glutamine synthetase is a genetic determinant of cell-type specific glutamine independence in breast epithelia.” In Cancer Research, Vol. 72, 2012. https://doi.org/10.1158/1538-7445.AM2012-3210.Full Text Link to Item
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Jin, Hongjun, Don S. Daly, Ruimin Tan, Amanda M. White, Jeffrey R. Marks, and Richard C. Zangar. “Abstract 3182: PTM ELISA microarray for breast cancer biomarker discovery.” In Cancer Research, 71:3182–3182. American Association for Cancer Research (AACR), 2011. https://doi.org/10.1158/1538-7445.am2011-3182.Full Text
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Untch, B. R., M Abdelgadir Adam, C. L. Tebbit, J. R. Marks, and J. A. Olson. “Tumor Sampling Variables Affect Reproducibility of Predictive Gene Expression Signatures in Breast Cancer.” In Annals of Surgical Oncology, 17:S30–S30. SPRINGER, 2010.Link to Item
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Baba, T., P. A. Convery, N. Matsumura, R. S. Whitaker, T. Perry, Z. Huang, S. Mori, et al. “Stem cell marker CD133 (PROMININ-1) is epigenetically regulated in ovarian cancer.” In Gynecologic Oncology, 108:S104–S104, 2008.Link to Item
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Baba, Tsukasa, Patricia Convey, Noriomi Matsumura, Regina S. Whitaker, Tiffany Perry, Zhiqing Huang, Seiichi Mori, et al. “Stem cell marker CD133 (PROMININ-1) is epigenetically regulated in ovarian cancer.” In Cancer Biomarkers, 4:175–76, 2008.Link to Item
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Danko, Melissa E., Brian R. Untch, Christopher L. Tebbit, Jun Zhai, Holly K. Dressman, Rex C. Bentley, Jay Baker, Jeffley R. Marks, Joseph R. Nevins, and John A Jr Olson. “A clinicogenomic model to predict lymph node metastasis in breast cancer.” In Journal of the American College of Surgeons, 207:S45–S45, 2008. https://doi.org/10.1016/j.jamcollsurg.2008.06.092.Full Text Link to Item
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Anders, C. K., S. D. Hsu, C. R. Acharya, Y. Zhang, Y. Wang, J. A. Foekens, P. K. Marcom, et al. “Molecular signatures characterize early stage breast cancer arising in young women and have prognostic and therapeutic implications independent of ER status.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Berchuck, Andrew, Johnathan M. Lancaster, Edwin S. Iversen, Jingqin Luo, Douglas A. Levine, Jeffrey Boyd, Angeles Alvarez Secord, Jeffrey R. Marks, Joseph R. Nevins, and Holly Dressman. “Most early-stage serous ovarian cancers have gene expression profiles predictive of long-term survival.” In Gynecologic Oncology, 104:S15–16. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2007.Link to Item
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Schildkraut, Joellen M., Amy French, Brian Calingaert, Rex C. Bentley, Susan Murphy, Jeffrey R. Marks, Patricia Moorman, Susan Halabi, and Andrew Berchuck. “Molecular epidemiology of cyclin E overexpression in epithelial ovarian cancer.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Tebbit, C. L., J. Pittman, M. J. Ellis, R. Bentley, H. Dressman, G. Mann, G. S. Leight, J. Nevins, J. R. Marks, and J. A. Olson. “Application of clinico-genomic models that predict breast cancer characteristics in a prospective study.” In Annals of Surgical Oncology, 12:S68–S68. SPRINGER, 2005.Link to Item
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Tebbit, C. L., J. R. Marks, H. Dressman, C. Blanchette, E. Iverson, J. Pittman, and J. A. Olson. “Gene expression signature characterizing cyclin E protein overexpression in primary breast tumors.” In Journal of the American College of Surgeons, 199:S78–79. ELSEVIER SCIENCE INC, 2004.Link to Item
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Berchuck, A., E. Iversen, J. M. Lancaster, A. Henriott, H. Dressman, M. West, J. R. Nevins, and J. R. Marks. “Prediction of long-term versus short-term survival in advanced stage serous ovarian cancer using expression microarrays.” In Journal of the Society for Gynecologic Investigation, 11:182A-182A. ELSEVIER SCIENCE INC, 2004.Link to Item
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Tebbit, C. L., J. R. Marks, E. J. Matthew, R. Eric, L. S. George, M. Gretchen, D. Holly, B. Rex, N. Joseph, and O. A. John. “Gene expression profiling can predict the extensive intraductal component phenotype in breast cancer.” In Breast Cancer Research and Treatment, 88:S112–S112. SPRINGER, 2004.Link to Item
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Pittman, J. L., C. L. Tebbit, E. P. Black, H. K. Dressman, E. S. Huang, J. A. Olson, J. R. Marks, et al. “Predictive models that combine multiple forms of genomic and clinical data to achieve personalized prediction of outcomes in breast cancer.” In Breast Cancer Research and Treatment, 88:S21–22. SPRINGER, 2004.Link to Item
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Berchuck, A., A. Henriott, R. M. Wenham, B. Calingaert, S. Ali, G. C. Rodriguez, J. R. Marks, and J. M. Schildkraut. “Progesterone receptor promoter+331/G/A polymorphism is associated with deceased risk of epithelial ovarian cancer.” In Cancer Epidemiology Biomarkers & Prevention, 12:1340S-1340S. AMER ASSOC CANCER RESEARCH, 2003.Link to Item
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Blackwell, K. L., M. W. Dewhirst, D. P. McDonnell, H. Dressman, S. A. Snyder, and J. R. Marks. “MTA-1 (metastasis associated protein-1) is upregulated in tamoxifen-resistant breast cancer.” In Breast Cancer Research and Treatment, 82:S88–S88. KLUWER ACADEMIC PUBL, 2003.Link to Item
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Tebbit, C. L., M. Ellis, J. R. Marks, R. C. Bentley, G. Mann, M. S. Soo, E. Rosen, J. Baker, G. Leight, and J. A. Olson. “Development of a novel tissue acquisition protocol for biomarker studies in early stage breast cancer.” In Breast Cancer Research and Treatment, 82:S143–44, 2003.Link to Item
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Marks, J. R., N. M. Brown, T. T. Stenzel, L. Roberts, J. Henslee, and P. Friedman. “Evaluation of new expression-based markers for detection of breast cancer cells.” In Clinical Cancer Research, 7:3688S-3688S. AMER ASSOC CANCER RESEARCH, 2001.Link to Item
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Young, S. R., N. Kataoka, Z. Wang, H. Kato, W. T. Loging, J. R. Marks, and N. Lehman. “BRCA1 copy number in paraffin embedded cancer tissue samples of known BRCA1 and BRCA2 mutation carriers using a BRCA1 FISH probe.” In American Journal of Human Genetics, 67:74–74. UNIV CHICAGO PRESS, 2000.Link to Item
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Frey, A. B., C. Lopez, H. Feiner, R. Shapiro, J. Marks, and T. D. Rao. “Repression of IL-2 mRNA translation in primary human breast cancer tumor infiltrating lymphocytes.” In Faseb Journal, Vol. 12, 1998.
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Hetiasch, J. M., Z. Haroon, M. W. Dewhirst, J. Marks, D. Iglehart, K. Peters, and C. S. Greenberg. “Tissue transglutaminase is associated with the neovasculature and extracellular matrix of human breast cancer.” In Faseb Journal, Vol. 10, 1996.
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KRIGMAN, H. R., A. ELBENDARY, and J. R. MARKS. “GLANDULAR AND STROMAL OVEREXPRESSION OF P53 IN MIXED MALIGNANT MESODERMAL TUMORS (MMMT) - AN ARGUMENT FOR CLONAL ORIGIN.” In Laboratory Investigation, 72:A92–A92. WILLIAMS & WILKINS, 1995.Link to Item
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