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Martha Kenney

Assistant Professor in Anesthesiology
Anesthesiology, Pediatrics

Overview


Martha Kenney, MD, is an Assistant Professor in the Department of Anesthesiology & Pediatrics at Duke University School of Medicine. She is an interdisciplinary pain researcher with expertise in pain management and physiology and pain processing in children and adolescents. Her research focuses on identifying modifiable risk factors for adverse pain outcomes in adolescents and young adults with complex painful conditions, especially sickle cell disease (SCD), and increasing community research engagement amongst underrepresented communities. Dr.  Kenney has a strong track record in SCD pain research. She is supported by a National Heart, Lung, and Blood Institute (NHLBI) Career Development Award (K01-HL169339-01) and a Patient-Centered Outcomes Research Institute (PCORI)engagement award. Her pain expertise has been recognized nationally. She contributed to the PhenX Sickle Cell Pain Working Group, establishing consensus on pain-specific patient-reported outcomes, and served on the U.S. Association for the Study of Pain’s (USASP) Patient Advisory Taskforce. She holds several leadership positions with national organizations, including as an expert member of the National Academies of Sciences, Engineering & Medicine’s (NASEM) Committee on Sickle Cell Disease in Social Security Disability Evaluations, a working group member of the Sickle Cell Disease Pain Analgesia and Integrative Network (SCDPAIN), a member of the National Pain Advocacy Center Scientific Advisory Council, a guest editor for The Journal of Pain, and the co-chair for the Diversity, Equity and Anti-racism Small Group of the USASP. Previously, she had an investigator-initiated grant by Global Blood Therapeutics which examined the impact of the COVID-19 pandemic on the pain management and care of sickle cell patients and on the operation of comprehensive sickle cell centers.

Dr. Kenney is a dually trained in general pediatrics and anesthesiology. She completed medical school, residency and fellowship trainings at Johns Hopkins School of Medicine and received her undergraduate degree in biochemistry from Brown University. Outside of her research, she is also certified professional coach with a focus on time management and work-life balance for women in academia.

Current Appointments & Affiliations


Assistant Professor in Anesthesiology · 2022 - Present Anesthesiology, Pediatrics, Anesthesiology
Assistant Professor in Medicine · 2025 - Present Medicine, Hematology, Medicine

In the News


Published October 9, 2024
Persisting to Help Children in PAIN

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Recent Publications


Exploring Perceived Barriers and Facilitators for Implementing Acute Pain Clinical Trials: A Mixed-Methods Analysis of Ketamine Infusions for Sickle Cell Pain.

Journal Article J Pain Res · 2025 OBJECTIVE: Vaso-occlusive events (VOEs) are the primary cause of acute pain in individuals with sickle cell disease (SCD), where high-dose opioids are the current standard treatment. Ketamine, a non-opioid analgesic, holds potential for managing acute SCD ... Full text Link to item Cite

Identifying distinct subgroups with severe pain in sickle cell disease: A cluster analysis of the GRNDaD multi-center registry.

Journal Article PLoS One · 2025 Sickle cell disease (SCD) affects millions of individuals worldwide, and is characterized by both acute, episodic pain and chronic, persistent pain. Despite the significant burden of the disease, clinicians continue to face significant challenges in treati ... Full text Link to item Cite

Altered pain processing and sensitization in sickle cell disease: a scoping review of quantitative sensory testing findings.

Journal Article Pain Med · February 1, 2024 OBJECTIVES: Over 50% of adults living with sickle cell disease (SCD) have chronic pain, but the underlying mechanisms of chronic pain in this population remain unclear. Quantitative sensory testing is an important measurement tool for understanding pain an ... Full text Link to item Cite
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Recent Grants


Creating a Theory of Change for Community-Driven Research in Sickle Cell Disease

ResearchPrincipal Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2025 - 2025

Predictors of Pain Severity and Pain-Related Outcomes in Individuals with Sickle Cell Disease

ResearchPrincipal Investigator · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2025

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Education, Training & Certifications


Johns Hopkins University · 2012 M.D.