Martin Fischer
Research Professor in the Department of Chemistry
Dr. Fischer’s research focuses on exploring novel nonlinear optical contrast mechanisms for molecular imaging. Nonlinear optical microscopes can provide non-invasive, high-resolution, 3-dimensional images even in highly scattering environments such as biological tissue.
Established contrast mechanisms, such as two-photon fluorescence or harmonic generation, can image a range of targets (such as autofluorescent markers or some connective tissue structure), but many of the most molecularly specific nonlinear interactions are harder to measure with power levels one might be willing to put on tissue. In order to use these previously inaccessible interactions as structural and molecular image contrasts we are developing ultrafast laser pulse shaping and pulse shape detection methods that dramatically enhance measurement sensitivity. Applications of these microscopy methods range from imaging biological tissue (mapping structure, endogenous tissue markers, or exogenous contrast agents) to characterization of nanomaterials (such as graphene and gold nanoparticles). The molecular contrast mechanisms we originally developed for biomedical imaging also provide pigment-specific signatures for paints used in historic artwork. Recently we have demonstrated that we can noninvasively image paint layers in historic paintings and we are currently developing microscopy techniques for use in art conservation and conservation science.
Current Appointments & Affiliations
- Research Professor in the Department of Chemistry, Chemistry, Trinity College of Arts & Sciences 2022
- Research Professor of Physics, Physics, Trinity College of Arts & Sciences 2022
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2008
Contact Information
- 2216 French Science Center, 124 Science Drive, Durham, NC 27708
- Box 90346, Durham, NC 27708-0346
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martin.fischer@duke.edu
(919) 660-1523
- Background
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Education, Training, & Certifications
- Ph.D., University of Texas, Austin 2001
- M.A., University of Texas, Austin 1993
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Previous Appointments & Affiliations
- Associate Research Professor in the Department of Chemistry, Chemistry, Trinity College of Arts & Sciences 2013 - 2022
- Associate Research Professor of Physics, Physics, Trinity College of Arts & Sciences 2018 - 2022
- Associate Research Professor of Physics, Physics, Trinity College of Arts & Sciences 2016 - 2018
- Assistant Research Professor of Chemistry, Chemistry, Trinity College of Arts & Sciences 2006 - 2013
- Recognition
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In the News
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AUG 13, 2020 -
AUG 9, 2020 Duke Health News -
MAR 19, 2019 -
JAN 22, 2014 Duke Today -
JAN 22, 2014
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- Expertise
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Subject Headings
- Research
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Selected Grants
- Next-Generation Optical Contrasts for Characterization of Biological Tissue, Hard Matter, and Cultural Heritage Objects awarded by National Science Foundation 2021 - 2024
- Advanced Light Imaging and Spectroscopy (ALIS) awarded by Chan Zuckerberg Initiative 2019 - 2024
- LUMICKS C-TRAP awarded by National Institutes of Health 2022 - 2023
- OP: Collaborative Research: Multimodal Molecular Spectroscopy and Imaging in Biological Tissue and Historical Artwork awarded by National Science Foundation 2016 - 2019
- Improving Melanoma Diagnosis with Pump-Probe Optical Imaging awarded by National Institutes of Health 2013 - 2017
- Collaborative Research: Development of Novel Nonlinear Optical Contrast for High-Resolution Morphological and Chemical Imaging of Historical Artwork awarded by National Science Foundation 2013 - 2017
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External Relationships
- American Association for the Advancement of Science
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Grass, David, Georgia M. Beasley, Martin C. Fischer, M Angelica Selim, Yue Zhou, and Warren S. Warren. “Contrast mechanisms in pump-probe microscopy of melanin.” Opt Express 30, no. 18 (August 29, 2022): 31852–62. https://doi.org/10.1364/OE.469506.Full Text Link to Item
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McKeown Wessler, Garrett C., Tianlin Wang, Jon-Paul Sun, Yuheng Liao, Martin C. Fischer, Volker Blum, and David B. Mitzi. “Structural, Optical, and Electronic Properties of Two Quaternary Chalcogenide Semiconductors: Ag2SrSiS4 and Ag2SrGeS4.” Inorganic Chemistry 60, no. 16 (August 2021): 12206–17. https://doi.org/10.1021/acs.inorgchem.1c01416.Full Text
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Jiang, Jun, David Grass, Yue Zhou, Warren S. Warren, and Martin C. Fischer. “Beyond intensity modulation: new approaches to pump-probe microscopy.” Optics Letters 46, no. 6 (March 2021): 1474–77. https://doi.org/10.1364/ol.417905.Full Text
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Fischer, Emma P., Martin C. Fischer, David Grass, Isaac Henrion, Warren S. Warren, and Eric Westman. “Low-cost measurement of face mask efficacy for filtering expelled droplets during speech.” Sci Adv 6, no. 36 (September 2020). https://doi.org/10.1126/sciadv.abd3083.Full Text Link to Item
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Fischer, Emma P., Martin C. Fischer, David Grass, Isaac Henrion, Warren S. Warren, and Eric Westman. “Low-cost measurement of facemask efficacy for filtering expelled droplets during speech,” June 22, 2020. https://doi.org/10.1101/2020.06.19.20132969.Full Text
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Jiang, Jun, Warren S. Warren, and Martin C. Fischer. “Crossed-beam pump-probe microscopy.” Optics Express 28, no. 8 (April 13, 2020): 11259–11259. https://doi.org/10.1364/oe.389004.Full Text
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Yu, Jin, Zhongguo Li, Charles Kolodziej, Seher Kuyuldar, Warren S. Warren, Clemens Burda, and Martin C. Fischer. “Visualizing the impact of chloride addition on the microscopic carrier dynamics of MAPbI3 thin films using femtosecond transient absorption microscopy.” The Journal of Chemical Physics 151, no. 23 (December 21, 2019): 234710–234710. https://doi.org/10.1063/1.5127875.Full Text
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Yu, Jin, Zhongguo Li, Yuheng Liao, Charles Kolodziej, Seher Kuyuldar, Warren S. Warren, Clemens Burda, and Martin C. Fischer. “Probing the Spatial Heterogeneity of Carrier Relaxation Dynamics in CH 3 NH 3 PbI 3 Perovskite Thin Films with Femtosecond Time‐Resolved Nonlinear Optical Microscopy.” Advanced Optical Materials 7, no. 22 (November 2019): 1901185–1901185. https://doi.org/10.1002/adom.201901185.Full Text
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Yu, Jin, Warren S. Warren, and Martin C. Fischer. “Visualization of vermilion degradation using pump-probe microscopy.” Science Advances 5, no. 6 (June 7, 2019). https://doi.org/10.1126/sciadv.aaw3136.Full Text
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Yang, Joel K. W., Martina Mrongovius, Martin C. Fischer, and Alexandra Boltasseva. “Design, Manufacture, and Analysis of Photonic Materials for Historical and Modern Visual Art: feature issue introduction.” Optical Materials Express 9, no. 5 (May 1, 2019): 2128–2128. https://doi.org/10.1364/ome.9.002128.Full Text
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Ju, Kuk-Youn, Simone Degan, Martin C. Fischer, Kevin C. Zhou, Xiaomeng Jia, Jin Yu, and Warren S. Warren. “Unraveling the molecular nature of melanin changes in metastatic cancer.” Journal of Biomedical Optics 24, no. 05 (April 11, 2019): 1–1. https://doi.org/10.1117/1.jbo.24.5.051414.Full Text
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Ju, Kuk-Youn, Martin C. Fischer, and Warren S. Warren. “Understanding the Role of Aggregation in the Broad Absorption Bands of Eumelanin.” Acs Nano 12, no. 12 (December 26, 2018): 12050–61. https://doi.org/10.1021/acsnano.8b04905.Full Text
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Yu, Jin, Warren S. Warren, and Martin C. Fischer. “Spectroscopic Differentiation and Microscopic Imaging of Red Organic Pigments Using Optical Pump–Probe Contrast.” Analytical Chemistry 90, no. 21 (November 6, 2018): 12686–91. https://doi.org/10.1021/acs.analchem.8b02949.Full Text
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Liu, Xiaojun, Xiaomeng Jia, Martin Fischer, Zhiqin Huang, and David R. Smith. “Enhanced Two-Photon Photochromism in Metasurface Perfect Absorbers.” Nano Letters 18, no. 10 (October 10, 2018): 6181–87. https://doi.org/10.1021/acs.nanolett.8b02042.Full Text
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Stanton, Ian N., Jennifer A. Ayres, Joshua T. Stecher, Martin C. Fischer, Dan Scharpf, Jonathan D. Scheuch, and Michael J. Therien. “Power-Dependent Radiant Flux and Absolute Quantum Yields of Upconversion Nanocrystals under Continuous and Pulsed Excitation.” The Journal of Physical Chemistry C 122, no. 1 (January 11, 2018): 252–59. https://doi.org/10.1021/acs.jpcc.7b11929.Full Text
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Wilson, Jesse W., Francisco E. Robles, Sanghamitra Deb, Warren S. Warren, and Martin C. Fischer. “Comparison of pump-probe and hyperspectral imaging in unstained histology sections of pigmented lesions.” Biomedical Optics Express 8, no. 8 (August 1, 2017): 3882–3882. https://doi.org/10.1364/boe.8.003882.Full Text
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Robles, Francisco E., Sanghamitra Deb, Martin C. Fischer, Warren S. Warren, and Maria Angelica Selim. “Label-Free Imaging of Female Genital Tract Melanocytic Lesions With Pump-Probe Microscopy: A Promising Diagnostic Tool.” J Low Genit Tract Dis 21, no. 2 (April 2017): 137–44. https://doi.org/10.1097/LGT.0000000000000290.Full Text Link to Item
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Robles, Francisco E., Kevin C. Zhou, Martin C. Fischer, and Warren S. Warren. “Stimulated Raman scattering spectroscopic optical coherence tomography.” Optica 4, no. 2 (February 20, 2017): 243–243. https://doi.org/10.1364/optica.4.000243.Full Text
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Villafana, Tana E., John K. Delaney, Warren S. Warren, and Martin C. Fischer. “High-resolution, three-dimensional imaging of pigments and support in paper and textiles.” Journal of Cultural Heritage 20 (July 2016): 583–88. https://doi.org/10.1016/j.culher.2016.02.003.Full Text
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Fischer, Martin C., Jesse W. Wilson, Francisco E. Robles, and Warren S. Warren. “Invited Review Article: Pump-probe microscopy.” Review of Scientific Instruments 87, no. 3 (March 2016): 031101–031101. https://doi.org/10.1063/1.4943211.Full Text
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Robles, Francisco E., Martin C. Fischer, and Warren S. Warren. “Dispersion-based stimulated Raman scattering spectroscopy, holography, and optical coherence tomography.” Optics Express 24, no. 1 (January 11, 2016): 485–485. https://doi.org/10.1364/oe.24.000485.Full Text
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Robles, Francisco E., Sanghamitra Deb, Jesse W. Wilson, Christina S. Gainey, M Angelica Selim, Paul J. Mosca, Douglas S. Tyler, Martin C. Fischer, and Warren S. Warren. “Pump-probe imaging of pigmented cutaneous melanoma primary lesions gives insight into metastatic potential.” Biomed Opt Express 6, no. 9 (September 1, 2015): 3631–45. https://doi.org/10.1364/BOE.6.003631.Full Text Link to Item
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Wilson, Jesse W., Jong Kang Park, Warren S. Warren, and Martin C. Fischer. “Flexible digital signal processing architecture for narrowband and spread-spectrum lock-in detection in multiphoton microscopy and time-resolved spectroscopy.” Review of Scientific Instruments 86, no. 3 (March 2015): 033707–033707. https://doi.org/10.1063/1.4916261.Full Text
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Park, Jong Kang, Martin C. Fischer, Kimihiro Susumu, Michael J. Therien, and Warren S. Warren. “Femtosecond pulse train shaping improves two-photon excited fluorescence measurements.” Optics Letters 39, no. 19 (October 1, 2014): 5606–5606. https://doi.org/10.1364/ol.39.005606.Full Text
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Robles, Francisco E., Martin C. Fischer, and Warren S. Warren. “Femtosecond pulse shaping enables detection of optical Kerr-effect (OKE) dynamics for molecular imaging.” Optics Letters 39, no. 16 (August 15, 2014): 4788–4788. https://doi.org/10.1364/ol.39.004788.Full Text
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Villafana, Tana Elizabeth, William P. Brown, John K. Delaney, Michael Palmer, Warren S. Warren, and Martin C. Fischer. “Femtosecond pump-probe microscopy generates virtual cross-sections in historic artwork.” Proceedings of the National Academy of Sciences 111, no. 5 (February 4, 2014): 1708–13. https://doi.org/10.1073/pnas.1317230111.Full Text
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Fischer, Martin. “Shedding new light on old art.” Physics World 26, no. 12 (December 2013): 19–23. https://doi.org/10.1088/2058-7058/26/12/30.Full Text
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Wilson, Jesse W., Simone Degan, Warren S. Warren, and Martin C. Fischer. “Optical clearing of archive-compatible paraffin embedded tissue for multiphoton microscopy: erratum.” Biomedical Optics Express 4, no. 2 (February 1, 2013): 219–219. https://doi.org/10.1364/boe.4.000219.Full Text
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Li, Baolei, Yingwen Cheng, Jie Liu, Congwen Yi, April S. Brown, Hsiangkuo Yuan, Tuan Vo-Dinh, Martin C. Fischer, and Warren S. Warren. “Direct Optical Imaging of Graphene In Vitro by Nonlinear Femtosecond Laser Spectral Reshaping.” Nano Letters 12, no. 11 (November 14, 2012): 5936–40. https://doi.org/10.1021/nl303358p.Full Text
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Wilson, Jesse W., Simone Degan, Warren S. Warren, and Martin C. Fischer. “Optical clearing of archive-compatible paraffin embedded tissue for multiphoton microscopy.” Biomedical Optics Express 3, no. 11 (November 1, 2012): 2752–2752. https://doi.org/10.1364/boe.3.002752.Full Text
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Robles, Francisco E., Jesse W. Wilson, Martin C. Fischer, and Warren S. Warren. “Phasor analysis for nonlinear pump-probe microscopy.” Optics Express 20, no. 15 (July 16, 2012): 17082–17082. https://doi.org/10.1364/oe.20.017082.Full Text
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Li, Baolei, Kevin E. Claytor, Hsiangkuo Yuan, Tuan Vo-Dinh, Warren S. Warren, and Martin C. Fischer. “Multicontrast nonlinear optical microscopy with a compact and rapid pulse shaper.” Optics Letters 37, no. 13 (July 1, 2012): 2763–2763. https://doi.org/10.1364/ol.37.002763.Full Text
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Wilson, Jesse W., Prathyush Samineni, Warren S. Warren, and Martin C. Fischer. “Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope.” Biomedical Optics Express 3, no. 5 (May 1, 2012): 854–854. https://doi.org/10.1364/boe.3.000854.Full Text
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Samineni, Prathyush, Adele deCruz, Tana E. Villafaña, Warren S. Warren, and Martin C. Fischer. “Pump-probe imaging of historical pigments used in paintings.” Optics Letters 37, no. 8 (April 15, 2012): 1310–1310. https://doi.org/10.1364/ol.37.001310.Full Text
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Samineni, Prathyush, Baolei Li, Jesse W. Wilson, Warren S. Warren, and Martin C. Fischer. “Cross-phase modulation imaging.” Optics Letters 37, no. 5 (March 1, 2012): 800–800. https://doi.org/10.1364/ol.37.000800.Full Text
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Zhang, R., J. A. Greenberg, M. C. Fischer, and D. J. Gauthier. “Controllable ultrabroadband slow light in a warm rubidium vapor.” Journal of the Optical Society of America B: Optical Physics 28, no. 11 (2011): 2578–83. https://doi.org/10.1364/JOSAB.28.002578.Full Text Open Access Copy
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Li, Baolei, Warren S. Warren, and Martin C. Fischer. “Phase-cycling coherent anti-Stokes Raman scattering using shaped femtosecond laser pulses.” Optics Express 18, no. 25 (December 6, 2010): 25825–25825. https://doi.org/10.1364/oe.18.025825.Full Text
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Samineni, Prathyush, Zachary Perret, Warren S. Warren, and Martin C. Fischer. “Measurements of nonlinear refractive index in scattering media.” Optics Express 18, no. 12 (June 7, 2010): 12727–12727. https://doi.org/10.1364/oe.18.012727.Full Text Open Access Copy
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Piletic, Ivan R., Martin C. Fischer, Prathyush Samineni, Gunay Yurtsever, and Warren S. Warren. “Rapid pulse shaping with homodyne detection for measuring nonlinear optical signals.” Optics Letters 33, no. 13 (July 1, 2008): 1482–1482. https://doi.org/10.1364/ol.33.001482.Full Text
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Fischer, Martin C., Henry C. Liu, Ivan R. Piletic, and Warren S. Warren. “Simultaneous self-phase modulation and two-photon absorption measurement by a spectral homodyne Z-scan method.” Optics Express 16, no. 6 (March 17, 2008): 4192–4192. https://doi.org/10.1364/oe.16.004192.Full Text
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Emami, Kiarash, Robert V. Cadman, John M. Woodburn, Martin C. Fischer, Stephen J. Kadlecek, Jianliang Zhu, Stephen Pickup, et al. “Early changes of lung function and structure in an elastase model of emphysema—a hyperpolarized3He MRI study.” Journal of Applied Physiology 104, no. 3 (March 2008): 773–86. https://doi.org/10.1152/japplphysiol.00482.2007.Full Text
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Fischer, Martin C., Henry C. Liu, Ivan R. Piletic, Yasmin Escobedo-Lozoya, Ryohei Yasuda, and Warren S. Warren. “Self-phase modulation signatures of neuronal activity.” Optics Letters 33, no. 3 (February 1, 2008): 219–219. https://doi.org/10.1364/ol.33.000219.Full Text
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Warren, W. S., M. C. Fischer, and Y. Tong. “Novel nonlinear contrast improves deep-tissue microscopy.” Laser Focus World 43, no. 6 (June 1, 2007): 99–103.
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Kadlecek, Stephen J., Kiarash Emami, Martin C. Fischer, Masaru Ishii, Jiangsheng Yu, John M. Woodburn, Mehdi NikKhah, et al. “Corrigendum to “Imaging physiological parameters with hyperpolarized gas MRI” Progress in NMR Spectrosc. 47 (2005) 187.” Progress in Nuclear Magnetic Resonance Spectroscopy 48, no. 4 (July 2006): 233–35. https://doi.org/10.1016/j.pnmrs.2006.05.001.Full Text
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KADLECEK, S., K. EMAMI, M. FISCHER, M. ISHII, J. YU, J. WOODBURN, M. NIKKHAH, V. VAHDAT, D. LIPSON, and J. BAUMGARDNER. “Imaging physiological parameters with hyperpolarized gas MRI.” Progress in Nuclear Magnetic Resonance Spectroscopy 47, no. 3–4 (December 15, 2005): 187–212. https://doi.org/10.1016/j.pnmrs.2005.08.006.Full Text
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Fischer, Martin C., Stephen Kadlecek, Jiangsheng Yu, Masaru Ishii, Kiarash Emami, Vahid Vahdat, David A. Lipson, and Rahim R. Rizi. “Measurements of Regional Alveolar Oxygen Pressure Using Hyperpolarized 3He MRI1.” Academic Radiology 12, no. 11 (November 2005): 1430–39. https://doi.org/10.1016/j.acra.2005.07.007.Full Text
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Haczku, Angela, Kiarash Emami, Martin C. Fischer, Stephen Kadlecek, Masaru Ishii, Reynold A. Panettieri, and Rahim R. Rizi. “Hyperpolarized 3He MRI in Asthma.” Academic Radiology 12, no. 11 (November 2005): 1362–70. https://doi.org/10.1016/j.acra.2005.08.027.Full Text
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Fischer, Martin C., Tong Ye, Gunay Yurtsever, Anthony Miller, Maria Ciocca, Wolfgang Wagner, and Warren S. Warren. “Two-photon absorption and self-phase modulation measurements with shaped femtosecond laser pulses.” Optics Letters 30, no. 12 (June 15, 2005): 1551–1551. https://doi.org/10.1364/ol.30.001551.Full Text
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Spector, Z. Z., K. Emami, M. C. Fischer, J. Zhu, M. Ishii, V. Vahdat, J. Yu, et al. “Quantitative assessment of emphysema using hyperpolarized 3He magnetic resonance imaging.” Magn Reson Med 53, no. 6 (June 2005): 1341–46. https://doi.org/10.1002/mrm.20514.Full Text Link to Item
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Ishii, Masaru, Martin C. Fischer, Kiarash Emami, Abass Alavi, Zebulon Z. Spector, Jiangsheng Yu, James E. Baumgardner, et al. “Hyperpolarized helium-3 MR imaging of pulmonary function.” Radiol Clin North Am 43, no. 1 (January 2005): 235–46. https://doi.org/10.1016/j.rcl.2004.09.010.Full Text Link to Item
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Spector, Z. Z., K. Emami, M. C. Fischer, J. Zhu, M. Ishii, J. Yu, S. Kadlecek, et al. “A small animal model of regional alveolar ventilation using HP 3He MRI1.” Acad Radiol 11, no. 10 (October 2004): 1171–79. https://doi.org/10.1016/j.acra.2004.08.001.Full Text Link to Item
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Fischer, M. C., Z. Z. Spector, M. Ishii, J. Yu, K. Emami, M. Itkin, and R. Rizi. “Single-acquisition sequence for the measurement of oxygen partial pressure by hyperpolarized gas MRI.” Magn Reson Med 52, no. 4 (October 2004): 766–73. https://doi.org/10.1002/mrm.20239.Full Text Link to Item
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Fischer, M. C., G. C. Gupta, L. L. Wang, K. Kojima, O. Mizuhara, and V. Swaminathan. “FEC performance under optical power transient conditions.” Ieee Photonics Technology Letters 15, no. 11 (November 2003): 1654–56. https://doi.org/10.1109/lpt.2003.818665.Full Text
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Soole, J. B. D., R. Pafchek, C. Narayanan, G. Bogert, L. Jampanaboyana, N. Chand, J. Yu, et al. “DWDM performance of a packaged reconfigurable optical add-drop multiplexer subsystem supporting modular systems growth.” Ieee Photonics Technology Letters 15, no. 11 (November 2003): 1600–1602. https://doi.org/10.1109/lpt.2003.818673.Full Text
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Jianjun Yu, V., M. Fischer, N. Chand, K. Kojima, and V. Swaminathan. “10-Gb/s transmission over 200-km conventional fiber without dispersion compensation using the bias control technique.” Ieee Photonics Technology Letters 14, no. 12 (December 2002): 1746–48. https://doi.org/10.1109/lpt.2002.804668.Full Text
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Shin, D. S., J. Wang, F. Bosch, P. A. Kiely, N. Chand, M. Fischer, K. Kojima, B. L. Kasper, E. M. Peral, and H. Ransijn. “10 Gbit∕s transmission over 50 km nonzero dispersion-shifted fibre using 1.3 [micro sign]m directly modulated uncooled transmitters.” Electronics Letters 38, no. 16 (2002): 864–864. https://doi.org/10.1049/el:20020606.Full Text
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Fischer, M. C., A. M. Dudarev, B. Gutiérrez-Medina, and M. G. Raizen. “FM spectroscopy in recoil-induced resonances.” Journal of Optics B: Quantum and Semiclassical Optics 3, no. 4 (August 1, 2001): 279–87. https://doi.org/10.1088/1464-4266/3/4/313.Full Text
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Fischer, M. C., B. Gutiérrez-Medina, and M. G. Raizen. “Observation of the Quantum Zeno and Anti-Zeno Effects in an Unstable System.” Physical Review Letters 87, no. 4 (July 10, 2001). https://doi.org/10.1103/physrevlett.87.040402.Full Text
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Madison, K. W., M. C. Fischer, and M. G. Raizen. “Observation of the Wannier-Stark fan and the fractional ladder in an accelerating optical lattice.” Physical Review A 60, no. 3 (September 1, 1999): R1767–70. https://doi.org/10.1103/physreva.60.r1767.Full Text
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Madison, K. W., M. C. Fischer, R. B. Diener, Qian Niu, and M. G. Raizen. “Dynamical Bloch Band Suppression in an Optical Lattice.” Physical Review Letters 81, no. 23 (December 7, 1998): 5093–96. https://doi.org/10.1103/physrevlett.81.5093.Full Text
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Fischer, M. C., K. W. Madison, Qian Niu, and M. G. Raizen. “Observation of Rabi oscillations between Bloch bands in an optical potential.” Physical Review A 58, no. 4 (October 1, 1998): R2648–51. https://doi.org/10.1103/physreva.58.r2648.Full Text
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Wilkinson, Steven R., Cyrus F. Bharucha, Martin C. Fischer, Kirk W. Madison, Patrick R. Morrow, Qian Niu, Bala Sundaram, and Mark G. Raizen. “Experimental evidence for non-exponential decay in quantum tunnelling.” Nature 387, no. 6633 (June 1997): 575–77. https://doi.org/10.1038/42418.Full Text
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Book Sections
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Fischer, M. C., and M. G. Raizen. “Experiments on quantum transport of ultra-cold atoms in optical potentials,” 789:205–37, 2009. https://doi.org/10.1007/978-3-642-03174-8_8.Full Text
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Conference Papers
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Robles, Francisco E., Martin C. Fischer, and Warren S. Warren. “Dispersion-based stimulated Raman scattering spectroscopy, holography, and optical coherence tomography (Conference Presentation).” In Multiphoton Microscopy in the Biomedical Sciences Xvi, edited by Ammasi Periasamy, Peter T. So, and Karsten König. SPIE, 2016. https://doi.org/10.1117/12.2212875.Full Text
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Warren, W. S., F. Robles, M. Fischer, J. Wilson, S. Deb, K. Ju, and S. Degan. “Melanin-targeted nonlinear microscopy for label-free molecular diagnosis and staging.” In Optics Infobase Conference Papers, 2016. https://doi.org/10.1364/TRANSLATIONAL.2016.TTh3B.3.Full Text
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Villafana, Tana, Bill Brown, John Delaney, Martin Fischer, Warren Warren, and Stephan Stranick. “3D chemical imaging of historic artworks and cultural heritage materials.” In Abstracts of Papers of the American Chemical Society, Vol. 251. AMER CHEMICAL SOC, 2016.Link to Item
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Wilson, J. W., W. S. Warren, and M. C. Fischer. “Real-time digital signal processing in multiphoton and time-resolved microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9703, 2016. https://doi.org/10.1117/12.2218102.Full Text
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Villafana, T. E., W. Brown, W. S. Warren, and M. Fischer. “Ultrafast pump-probe dynamics of iron oxide based earth pigments for applications to ancient pottery manufacture.” In Proceedings of Spie the International Society for Optical Engineering, Vol. 9527, 2015. https://doi.org/10.1117/12.2184758.Full Text
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Wilson, J. W., M. Anderson, J. K. Park, M. C. Fischer, and W. S. Warren. “Separating higher-order nonlinearities in transient absorption microscopy.” In Proceedings of Spie the International Society for Optical Engineering, Vol. 9584, 2015. https://doi.org/10.1117/12.2187133.Full Text
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Fischer, M. C., T. E. Villafana, W. Brown, J. Delaney, and W. S. Warren. “Nonlinear Optical Imaging in Art Conservation and Heritage Science.” In Optics Infobase Conference Papers, 2015.
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Warren, W. S., M. Fischer, J. Wilson, F. Robles, and S. Deb. “Enhancing Pigmented or Transparent Tissue Imaging with Laser Pulse Shaping.” In Optics Infobase Conference Papers, 2015.
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Park, J. K., M. C. Fischer, K. Susumu, M. J. Therien, and W. S. Warren. “Femtosecond pulse train shaping for accurate two-photon excited fluorescence measurements.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/ls.2014.lth4h.3.Full Text
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Park, J. K., M. C. Fischer, K. Susumu, M. J. Therien, and W. S. Warren. “Femtosecond pulse train shaping for accurate two-photon excited fluorescence measurements.” In Laser Science, Ls 2014, 2014.
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Wilson, J. W., S. Degan, M. C. Fischer, and W. S. Warren. “Optical clearing and multiphoton imaging of paraffin-embedded specimens.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8588, 2013. https://doi.org/10.1117/12.2003155.Full Text
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Robles, F. E., J. W. Wilson, M. C. Fischer, and W. S. Warren. “Adapting phasor analysis for nonlinear pump-probe microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8589, 2013. https://doi.org/10.1117/12.2002600.Full Text
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Li, B., C. Yi, A. Brown, M. C. Fischer, and W. S. Warren. “Homodyne near-degenerate four-wave-mixing microscopy for graphene imaging and biomedical applications.” In 2012 Conference on Lasers and Electro Optics, Cleo 2012, 2012.
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Samineni, P., A. De Cruz, T. Villafana, M. C. Fischer, and W. S. Warren. “Pump-probe microscopy of pigments used in historical art.” In 2012 Conference on Lasers and Electro Optics, Cleo 2012, 2012.
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Wilson, J. W., P. Samineni, M. C. Fischer, and W. S. Warren. “Nonlinear cross-phase modulation microscopy using spectral shifting.” In 2012 Conference on Lasers and Electro Optics, Cleo 2012, 2012.
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Villafaña, T. E., P. Samineni, W. S. Warren, and M. C. Fischer. “Historical pigments revealed by pump-probe microscopy.” In Laser Science, Ls 2012, 2012.
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Claytor, K., B. Li, P. Samineni, W. Warren, and M. Fischer. “Femtosecond pulse shaping enables nonlinear imaging in highly scattering materials.” In Optics Infobase Conference Papers, 2011.
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Li, B., K. Claytor, W. S. Warren, and M. C. Fischer. “Optimizing shape of femtosecond laser pulses for homodyne detection of nonlinear optical signals.” In Optics Infobase Conference Papers, 2011.
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Samineni, P., M. C. Fischer, and W. S. Warren. “Cross-phase modulation microscopy.” In Optics Infobase Conference Papers, 2011.
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Fischer, M. C., P. Samineni, B. Li, K. Claytor, and W. S. Warren. “Accessing nonlinear phase contrast in biological tissue using femtosecond laser pulse shaping.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8086, 2011. https://doi.org/10.1117/12.889668.Full Text
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Claytor, K., B. Li, P. Samineni, W. Warren, and M. Fischer. “Femtosecond pulse shaping enables nonlinear imaging in highly scattering materials.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/ls.2011.lmc5.Full Text
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Li, B., K. Claytor, W. S. Warren, and M. C. Fischer. “Optimizing shape of femtosecond laser pulses for homodyne detection of nonlinear optical signals.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/fio.2011.ftuq5.Full Text
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Samineni, P., M. C. Fischer, H. C. Liu, R. Yasuda, and W. S. Warren. “Nonlinear phase contrast imaging in neuronal tissue.” In Optics Infobase Conference Papers, 2011.
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Samineni, P., M. C. Fischer, H. C. Liu, R. Yasuda, and W. S. Warren. “Nonlinear phase contrast imaging in neuronal tissue.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/ntm.2011.nmd3.Full Text
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Samineni, P., M. C. Fischer, and W. S. Warren. “Cross-phase modulation microscopy.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/ls.2011.ltua2.Full Text
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Li, B., W. S. Warren, and M. C. Fischer. “Enhancing coherent anti-stokes Raman scattering background suppression with phase cycled structured femtosecond laser pulses.” In Optics Infobase Conference Papers, 2010.
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Samineni, P., Z. Perret, W. S. Warren, and M. C. Fischer. “Femtosecond laser pulse shaping improves self-phase modulation measurements in scattering media.” In Optics Infobase Conference Papers, 2010.
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Li, B., W. S. Warren, and M. C. Fischer. “Enhancing coherent anti-stokes Raman scattering background suppression with phase cycled structured femtosecond laser pulses.” In Optics Infobase Conference Papers, 2010. https://doi.org/10.1364/fio.2010.ftuf2.Full Text
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Samineni, P., Z. Perret, W. S. Warren, and M. C. Fischer. “Femtosecond laser pulse shaping improves self-phase modulation measurements in scattering media.” In Optics Infobase Conference Papers, 2010. https://doi.org/10.1364/fio.2010.fthg2.Full Text
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Warren, W. S., I. Piletic, M. Fischer, D. Fu, P. Samenini, and T. Matthews. “Nonlinear microscopy without fluorescence: Seeing the needle in the Haystack with Femtosecond pulse shaping.” In Optics Infobase Conference Papers, 2009.
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Fischer, M. C., I. Piletica, D. Fub, T. E. Matthewsa, H. Liuc, P. Saminenia, B. Lid, and W. S. Warrene. “Enhancing two-color absorption, self-phase modulation and raman microscopy signatures in tissue with femtosecond laser pulse shaping.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7183, 2009. https://doi.org/10.1117/12.816488.Full Text
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Warren, W. S. “Tissue imaging with shaped femtosecond laser pulses.” In Optics Infobase Conference Papers, 2009.
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Warren, W. S., I. Piletic, M. Fischer, D. Fu, P. Samenini, and T. Matthews. “Nonlinear microscopy without fluorescence: Seeing the needle in the Haystack with Femtosecond pulse shaping.” In Optics Infobase Conference Papers, 2009. https://doi.org/10.1364/ntm.2009.nmc1.Full Text
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Warren, W. S., M. Fischer, D. Fu, T. Ye, I. Piletic, and T. Matthews. “New nonlinear signatures in spectroscopy and imaging.” In Conference on Quantum Electronics and Laser Science (Qels) Technical Digest Series, 2008. https://doi.org/10.1109/QELS.2008.4552901.Full Text
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Fischer, M. C., H. C. Liu, D. Fu, P. Semineni, T. Matthews, I. Piletic, and W. S. Warren. “Femtosecond laser pulse shaping for molecular imaging in biological tissue.” In Optics Infobase Conference Papers, 2008.
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Fischer, M. C., H. C. Liu, D. Fu, P. Semineni, T. Matthews, I. Piletic, and W. S. Warren. “Femtosecond laser pulse shaping for molecular imaging in biological tissue.” In Optics Infobase Conference Papers, 2008. https://doi.org/10.1364/fio.2008.ftuy1.Full Text
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Liu, H. C., M. C. Fischer, P. Samineni, Y. Escobedo-Lozoya, R. Yasuda, and W. S. Warren. “Intrinsic nonlinear optical signatures of neuronal activity.” In Optics Infobase Conference Papers, 2008.
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Liu, H. C., M. C. Fischer, P. Samineni, Y. Escobedo-Lozoya, R. Yasuda, and W. S. Warren. “Intrinsic nonlinear optical signatures of neuronal activity.” In Optics Infobase Conference Papers, 2008. https://doi.org/10.1364/fio.2008.fwd2.Full Text
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Piletic, I. R., M. C. Fischer, P. Samineni, and W. S. Warren. “Accessing nonlinear contrast in imaging using rapid pulse shaping techniques.” In Optics Infobase Conference Papers, 2008.
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Piletic, I. R., M. C. Fischer, P. Samineni, and W. S. Warren. “Accessing nonlinear contrast in imaging using rapid pulse shaping techniques.” In Optics Infobase Conference Papers, 2008. https://doi.org/10.1364/fio.2008.ftuy3.Full Text
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Fischer, M. C., H. Liu, I. R. Piletic, T. Ye, R. Yasuda, and W. S. Warren. “Self-phase modulation and two-photon absorption imaging of cells and active neurons.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 6442, 2007. https://doi.org/10.1117/12.698693.Full Text
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Ye, T., G. Yurtsever, M. Fischer, J. D. Simon, and W. S. Warren. “Imaging melanin by two-photon absorption microscopy.” In Proceedings of Spie the International Society for Optical Engineering, Vol. 6089, 2006. https://doi.org/10.1117/12.646139.Full Text
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Warren, W. S., T. Ye, M. Fischer, G. Yurtsever, C. Li, H. Liu, and D. Fu. “Deep tissue imaging with shaped femtosecond laser pulses.” In Optics Infobase Conference Papers, 2006.
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Fischer, M. C., T. Ye, G. Yurtsever, A. Miller, M. Ciocca, W. Wagner, and W. S. Warren. “Two-photon absorption and self-phase modulation measurements with shaped femtosecond laser pulses.” In 2005 Conference on Lasers and Electro Optics, Cleo, 2:968–70, 2005. https://doi.org/10.1109/cleo.2005.201992.Full Text
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Ye, T., M. Fischer, G. Yurtsever, and W. S. Warren. “Two-photon absorption microscopy of tissue.” In Optics Infobase Conference Papers, 2005.
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Warren, W. S., A. Miller, W. Wagner, T. Ye, M. Fischer, and G. Yurtsever. “Two-photon absorption imaging with shaped femtosecond laser pulses.” In Springer Series in Chemical Physics, 79:867–69, 2004.
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Ye, T., W. Wagner, P. Tian, G. Yurtsever, M. Fischer, and W. S. Warren. “Deep tissue imaging approaches by direct capture of two-photon absorption.” In 2004 2nd Ieee International Symposium on Biomedical Imaging: Macro to Nano, 1:668–71, 2004.
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Warren, W. S., A. Miller, W. Wagner, T. Ye, M. Fischer, and G. Yurtsever. “Two-photon absorption imaging and self-phase modulation imaging with shaped laser pulses.” In Optics Infobase Conference Papers, 2004.
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Warren, W. S., A. Miller, W. Wagner, T. Ye, M. Fischer, and G. Yurtsever. “Two-photon absorption imaging with shaped femtosecond laser pulses.” In Optics Infobase Conference Papers, 2004.
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Kojima, K., M. C. Fischer, N. Chand, D. Klotzkin, P. A. Kiely, J. Sheridan-Eng, Y. Xu, and G. Tohmon. “Effect of reflection on un-isolated spot-size-converted 1.3 μm DFB lasers for 2.5 Gbit/s transmission.” In Conference on Optical Fiber Communication, Technical Digest Series, 70:473–75, 2002.
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Kojima, K., M. C. Fischer, N. Chand, D. Klotzkin, P. A. Kiely, J. Sheridan-Eng, Y. Xu, and G. Tohmon. “Effect of reflection on un-isolated spot-size-converted 1.3 µm DFB lasers for 2.5 Gbit/s transmission.” In Optics Infobase Conference Papers, 473–75, 2002.
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Yu, J., K. Kojima, N. Chand, M. C. Fischer, R. Espindola, and T. G. B. Mason. “160GB/s single-channel unrepeatered transmission over 200km of non-zero dispersion shifted fiber.” In European Conference on Optical Communication, Ecoc, 6:20–21, 2001.
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Gutiérrez-Medina, B., M. C. Fischer, and M. G. Raizen. “Observation of the quantum zeno and anti-zeno effects in an unstable system.” In Technical Digest Summaries of Papers Presented at the Quantum Electronics and Laser Science Conference, Qels 2001, QPD1.1-QPD1.2, 2001. https://doi.org/10.1109/QELS.2001.962243.Full Text
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Fischer, M. C., K. W. Madison, R. B. Diener, Q. Niu, and M. G. Raizen. “Dynamical Bloch band suppression in an optical lattice.” In Iqec, International Quantum Electronics Conference Proceedings, 239–40, 1999.
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Fischer, M. C., K. W. Madison, R. B. Diener, Q. Niu, and M. G. Raizen. “Dynamical Bloch band suppression in an optical lattice.” In Optics Infobase Conference Papers, 1999.
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Madison, K. W., M. C. Fischer, Q. Niu, and M. G. Raizen. “Nonexponential decay in atomic tunneling.” In Technical Digest European Quantum Electronics Conference, 24, 1998.
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Madison, K. W., C. F. Bharucha, M. C. Fischer, S. R. Wilkinson, P. R. Morrow, Q. Niu, B. Sundaram, and M. G. Raizen. “Observation of non-exponential decay In quantum tunnelling.” In Optics Infobase Conference Papers, 1997.
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Datasets
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Fischer, Martin, Warren Warren, David Grass, Henrion Isaac, Eric Westman, and Emma Fischer. “Video data from: Low-cost measurement of facemask efficacy for filtering expelled droplets during speech,” August 5, 2020. https://doi.org/10.7924/r4ww7dx6q.Data Access
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Fischer, Martin, Jesse Wilson, Simone Degan, Warren Warren, Jennifer Zhang, Tanya Mitropoulos, Christina Gainey, and Mary Jane Simpson. “Data from: In vivo pump-probe and multiphoton fluorescence microscopy of melanoma and pigmented lesions in a mouse model,” July 15, 2019. https://doi.org/10.7924/r4cc0zp95.Data Access
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Preprints
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Grass, David, Georgia M. Beasley, Martin C. Fischer, M Angelica Selim, Yue Zhou, and Warren S. Warren. “Contrast mechanisms in pump-probe microscopy of melanin,” July 1, 2022.Link to Item
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- Scholarly, Clinical, & Service Activities
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Service to the Profession
- Reviewer : Optics Letters, Optics Express, Journal of Biomedical Optics, Review of Scientific Instruments, Optical Materials, Journal of Microscopy, British Jour. January 15, 2013 2013
- Program Committee : 2011 Frontiers in Optics/Laser Science meeting: “Techniques and Applications in Nonlinear Microscopy. December 14, 2011 2011
- Reviewer for OSA, AIP and SPIE journals. December 14, 2011 2011
- Session Chair : 2011 Frontiers in Optics / Laser Science: “Towards Clinical Applications of Nonlinear Microscopy” and “Bioplasmonics”. December 14, 2011 2011
- Session Chair : ECBO 2011: Clinical and Biomedical Spectroscopy and Imaging II. December 14, 2011 2011
- Co-Organizer, CMBI and Ultrafast Meeting. December 2, 2009 2009
- Panel Member for Career Seminar. December 2, 2009 2009
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