Scholars@Duke
Marvaretta Miesha Stevenson

Marvaretta Miesha Stevenson

Associate Professor of Medicine
Medicine, Medical Oncology
marvaretta.stevenson@duke.edu
3404 Wake Forest Road, Mob 7 Suite 201, Raleigh, NC 27609
3404 Wake Forest Road, Mob 7 Suite 201, Raleigh, NC 27609

Selected Publications

A Phase 2 Clinical Trial of Combination Nivolumab, Ipilimumab, and Paclitaxel in Patients With Untreated Metastatic NSCLC: The OPTIMAL Trial.

Journal Article JTO Clin Res Rep · June 2022 INTRODUCTION: Most patients with advanced NSCLC will experience disease progression and death within 2 years. Novel approaches are needed to improve outcomes. METHODS: We conducted an open-label, nonrandomized, phase 2 trial in patients with treatment-naiv ... Full text Link to item Cite

Tumor acquisition for biomarker research in lung cancer.

Journal Article Cancer Invest · July 2014 The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success ra ... Full text Link to item Cite

Occult primary, version 3.2014.

Journal Article J Natl Compr Canc Netw · July 2014 The NCCN Guidelines for Occult Primary tumors provide recommendations for the evaluation, workup, management, and follow-up of patients with occult primary tumors (cancers of unknown primary). These NCCN Guidelines Insights summarize major discussion point ... Full text Link to item Cite

Development of a virtual multidisciplinary lung cancer tumor board in a community setting.

Journal Article J Oncol Pract · May 2013 PURPOSE: Creating an effective platform for multidisciplinary tumor conferences can be challenging in the rural community setting. The Duke Cancer Network created an Internet-based platform for a multidisciplinary conference to enhance the care of patients ... Full text Link to item Cite

Development of a virtual multidisciplinary lung cancer tumor board in a community setting.

Journal Article Journal of Clinical Oncology · December 1, 2012 325 Background: Creating an effective platform for multidisciplinary tumor conferences can be challenging in the rural community setting. The Duke Oncology Network, which is affiliated with hospitals in rural locations throughout ... Full text Cite

A pathway-based approach to identify molecular biomarkers in cancer.

Journal Article Ann Surg Oncol · July 2012 Many examples highlight the power of gene expression profiles, or signatures, to provide an understanding of biological phenotypes. This is best seen in the context of cancer, where expression signatures have tremendous power to identify new cancer subtype ... Full text Link to item Cite

Age- and sex-specific genomic profiles in non-small cell lung cancer.

Journal Article JAMA · February 10, 2010 CONTEXT: Gene expression profiling may be useful in examining differences underlying age- and sex-specific outcomes in non-small cell lung cancer (NSCLC). OBJECTIVE: To describe clinically relevant differences in the underlying biology of NSCLC based on pa ... Full text Link to item Cite

Characterizing the clinical relevance of an embryonic stem cell phenotype in lung adenocarcinoma.

Journal Article Clin Cancer Res · December 15, 2009 PURPOSE: Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear whether these phenotypic similarities are the result of a common biological phenotype, such as regulatory pathways. EXPERIMENTAL DESIGN: Lung cancer cell ... Full text Link to item Cite

Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia.

Journal Article J Clin Oncol · November 20, 2009 PURPOSE: To define the biology driving the aggressive nature of acute myeloid leukemia (AML) in elderly patients. PATIENTS AND METHODS: Clinically annotated microarray data from 425 patients with newly diagnosed de novo AML from two publicly available data ... Full text Link to item Cite

Characterizing the clinical relevance of an embryonic stem cell phenotype in lung adenocarcinoma.

Journal Article J Clin Oncol · May 20, 2009 11001 Background: Cancer cells possess traits reminiscent of those ascribed to normal stem cells. It is unclear whether these phenotypic similarities between normal/embryonic stem cells and mature tumor cells, specific to lung cancer, are a result of under ... Link to item Cite

Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer.

Journal Article Proc Natl Acad Sci U S A · March 31, 2009 We investigated the clinical implications of lung developmental transcription factors (TTF-1, NKX2-8, and PAX9) that we recently discovered as cooperating oncogenes activated by way of gene amplification at chromosome 14q13 in lung cancer. Using stable tra ... Full text Link to item Cite