Overview
Clinical Research in Neuromuscular diseases including myasthenia gravis, Lambert-Eaton myasthenic syndrome, botulinum toxins, electromyography, dystonic disorders including cervical dystonia (spasmodic torticollis), limb focal dystonia, and blepharospasm.
Current Appointments & Affiliations
Professor of Neurology
·
1999 - Present
Neurology, Neuromuscular Disease,
Neurology
Senior Vice Chair in the Department of Neurology
·
2017 - Present
Neurology,
Clinical Science Departments
Recent Publications
The Duke MG Patient Registry III. Comparative Effectiveness of Azathioprine and Mycophenolate Mofetil in Generalized Myasthenia Gravis, a Retrospective Single Center Review.
Conference Muscle Nerve · May 2026 INTRODUCTION/AIMS: Azathioprine (AZA) and mycophenolate mofetil (MMF) are the most commonly used non-steroidal immunosuppressants in patients with generalized myasthenia gravis (gMG) in North America but their relative effectiveness among disease subgroups ... Full text Link to item CiteCharacterizing Perinatal Treatment Patterns and Outcomes in Myasthenia Gravis.
Journal Article Muscle Nerve · February 2026 INTRODUCTION/AIMS: Studies on pregnancy in myasthenia gravis (MG) are limited by small sample sizes or examine a limited number of outcomes. The objective of this study was to estimate the prevalence of perinatal and infant outcomes and characterize perina ... Full text Link to item CiteSensitivity of Repetitive Nerve Stimulation Performed in Early and Later Stages of Myasthenia Gravis.
Journal Article Muscle Nerve · October 2025 INTRODUCTION/AIMS: Repetitive nerve stimulation (RNS) is a valuable tool in the diagnostic evaluation of myasthenia gravis (MG). However, there are conflicting reports of its sensitivity when performed ≤ 30 days from symptom onset. We aim to compare the se ... Full text Link to item CiteRecent Grants
A Phase 3, Open-Label, Multi-Center Trial to Evaluate the Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in
Clinical TrialPrincipal Investigator · Awarded by Revance Therapeutics Inc. · 2019 - 2021Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Trial to Evaluate the Efficacy and Safety of a Single Treatment of DaxibotulinumtoxinA for Injection in Adults with Isolated Cervical Dystonia (ASPEN-1)
Clinical TrialPrincipal Investigator · Awarded by Revance Therapeutics Inc. · 2019 - 20213,4-Diaminopyridine In Lambert-Eaton Syndrome
ResearchCo-Principal Investigator · Awarded by Food and Drug Administration · 1994 - 1998View All Grants
Education
Georgetown University ·
1990
M.D.