Overview
Clinical Research in Neuromuscular diseases including myasthenia gravis, Lambert-Eaton myasthenic syndrome, botulinum toxins, electromyography, dystonic disorders including cervical dystonia (spasmodic torticollis), limb focal dystonia, and blepharospasm.
Current Appointments & Affiliations
Professor of Neurology
·
1999 - Present
Neurology, Neuromuscular Disease,
Neurology
Senior Vice Chair in the Department of Neurology
·
2017 - Present
Neurology,
Clinical Science Departments
Recent Publications
Sensitivity of Repetitive Nerve Stimulation Performed in Early and Later Stages of Myasthenia Gravis.
Journal Article Muscle Nerve · October 2025 INTRODUCTION/AIMS: Repetitive nerve stimulation (RNS) is a valuable tool in the diagnostic evaluation of myasthenia gravis (MG). However, there are conflicting reports of its sensitivity when performed ≤ 30 days from symptom onset. We aim to compare the se ... Full text Link to item CiteComparative effectiveness of azathioprine and mycophenolate mofetil for myasthenia gravis (PROMISE-MG): a prospective cohort study.
Journal Article Lancet Neurol · March 2024 BACKGROUND: Myasthenia gravis is an autoimmune disorder of the neuromuscular junction. Treatment typically includes symptomatic oral cholinesterase inhibitors, immunosuppression, and immunomodulation. In addition to corticosteroids, azathioprine and mycoph ... Full text Link to item CitePregnancy in Seronegative Myasthenia Gravis: A Single-Center Case Series.
Journal Article J Clin Neuromuscul Dis · December 1, 2023 INTRODUCTION: The course of double-seronegative myasthenia gravis (DSNMG) during and after pregnancy has not been well described. OBJECTIVE: To assess the course of DSNMG during pregnancy and within 6 months postpartum. METHODS: A retrospective cohort stud ... Full text Link to item CiteRecent Grants
A Phase 3, Open-Label, Multi-Center Trial to Evaluate the Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in
Clinical TrialPrincipal Investigator · Awarded by Revance Therapeutics Inc. · 2019 - 2021Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Trial to Evaluate the Efficacy and Safety of a Single Treatment of DaxibotulinumtoxinA for Injection in Adults with Isolated Cervical Dystonia (ASPEN-1)
Clinical TrialPrincipal Investigator · Awarded by Revance Therapeutics Inc. · 2019 - 20213,4-Diaminopyridine In Lambert-Eaton Syndrome
ResearchCo-Principal Investigator · Awarded by Food and Drug Administration · 1994 - 1998View All Grants
Education, Training & Certifications
Georgetown University ·
1990
M.D.