Max Schiff

Journal Article J Neurosci · March 18, 2015 This study combines for the first time two major approaches to understanding the function and structure of neural circuits: large-scale multielectrode recordings, and confocal imaging of labeled neurons. To achieve this end, we develop a novel approach to ... Full text Open Access Link to item Cite

A polyaxonal amacrine cell population in the primate retina.

Journal Article J Neurosci · March 5, 2014 Amacrine cells are the most diverse and least understood cell class in the retina. Polyaxonal amacrine cells (PACs) are a unique subset identified by multiple long axonal processes. To explore their functional properties, populations of PACs were identifie ... Full text Open Access Link to item Cite

Characterization of thalamocortical responses of regular-spiking and fast-spiking neurons of the mouse auditory cortex in vitro and in silico

Journal Article Journal of Neurophysiology · March 1, 2012 We use a combination of in vitro whole cell recordings and computer simulations to characterize the cellular and synaptic properties that contribute to processing of auditory stimuli. Using a mouse thalamocortical slice preparation, we record the ... Full text Cite

Linking the Response Properties of Cells in Auditory Cortex with Network Architecture: Cotuning versus Lateral Inhibition

Journal Article The Journal of Neuroscience · September 10, 2008 The frequency-intensity receptive fields (RF) of neurons in primary auditory cortex (AI) are heterogeneous. Some neurons have V-shaped RFs, whereas others have enclosed ovoid RFs. Moreover, there is a wide range of temporal response profiles rangin ... Full text Cite

Synaptic mechanisms underlying auditory processing

Journal Article Current Opinion in Neurobiology · August 2006 Full text Cite

Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel.

Journal Article Nature · December 7, 2000 Gamma-aminobutyric acid (GABA)B receptors couple to Go to inhibit N-type calcium channels in embryonic chick dorsal root ganglion neurons. The voltage-independent inhibition, mediated by means of a tyrosine-kinase pathway, is transient and lasts up to 100 ... Full text Link to item Cite

Regulators of G protein signaling proteins as determinants of the rate of desensitization of presynaptic calcium channels.

Journal Article J Biol Chem · May 14, 1999 Norepinephrine inhibits omega-conotoxin GVIA-sensitive presynaptic Ca2+ channels in chick dorsal root ganglion neurons through two pathways, one mediated by Go and the other by Gi. These pathways desensitize at different rates. We have found that recombina ... Full text Link to item Cite