Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Resident, American University of Beirut (Lebannon) 2002 - 2005
  • Intern, American University of Beirut (Lebannon) 2001 - 2002
  • M.D., American University of Beirut (Lebannon) 2001
• 

  Duke Appointment History

  • Assistant Professor of Ophthalmology, Ophthalmology, Neuro-Ophthalmology, Ophthalmology 2009 - 2017
  • Clinical Associate in the Department of Ophthalmology, Ophthalmology, Neuro-Ophthalmology, Ophthalmology 2007 - 2009
  • Clinical Associate in the Department of Ophthalmology, Ophthalmology, Clinical Science Departments 2005 - 2007
• Research
• 

  Selected Grants

  • Analyzing retinal microanatomy in retinopathy of prematurity to improve care awarded by National Institutes of Health 2016 - 2020
  • An integrated and diverse genomic medicine program for undiagnosed diseases awarded by National Institutes of Health 2014 - 2018
  • Knight's Template OCT in Normal Children awarded by Knights Templar Eye Foundation, Inc. 2015 - 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Duncan, JE, Freedman, SF, and El-Dairi, MA. "Use of optical coherence tomography in the eyes of children." In Practical Management of Pediatric Ocular Disorders and Strabismus: A Case-based Approach, 271-290. July 27, 2016.  Full Text
    • El-Dairi, MA, and Bhatti, MT. "Optic neuritis in children." In Practical Management of Pediatric Ocular Disorders and Strabismus: A Case-based Approach, 427-438. July 27, 2016.  Full Text
    • El-Dairi, M, and Gospe, S. "Neuro-ophthalmology." In The Ophthalmology Clinical Trials Handbook, 379-424. January 1, 2015.

  • Conference Papers

    • Tong, AY, El-Dairi, M, Maldonado, RS, Rothman, AL, Yuan, EL, Stinnett, SS, Kupper, L, Cotten, CM, Gustafson, KE, Goldstein, RF, Freedman, SF, and Toth, CA. "Evaluation of optic nerve development in preterm and term infants using handheld spectral-domain optical coherence tomography." January 1, 2014.  Full Text

  • Journal Articles

    • Thompson, AC, and El-Dairi, MA. "Reply." Journal of Aapos : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus 22, no. 3 (June 2018): 248-249. (Letter)  Full Text
    • Pena, LDM, Jiang, Y-H, Schoch, K, Spillmann, RC, Walley, N, Stong, N, Rapisardo Horn, S, Sullivan, JA, McConkie-Rosell, A, Kansagra, S, Smith, EC, El-Dairi, M, Bellet, J, Keels, MA, Jasien, J, Kranz, PG, Noel, R, Nagaraj, SK, Lark, RK, Wechsler, DSG, Del Gaudio, D, Leung, ML, Hendon, LG, Parker, CC, Jones, KL, Undiagnosed Diseases Network Members, , Goldstein, DB, and Shashi, V. "Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases." Genetics in Medicine : Official Journal of the American College of Medical Genetics 20, no. 4 (April 2018): 464-469.  Full Text  Open Access Copy
    • El-Dairi, MA, and Bhatti, MT. "Temporary Lumbar Drain as Treatment for Pediatric Fulminant Idiopathic Intracranial Hypertension: Response." Journal of Neuro Ophthalmology : the Official Journal of the North American Neuro Ophthalmology Society 38, no. 1 (March 2018): 122-123.  Full Text
    • Mali, YP, and El-Dairi, M. "Diagnosis and Management of Pediatric Orbital Diseases." International Ophthalmology Clinics 58, no. 2 (2018): 111-136.  Full Text
    • Thompson, AC, Bhatti, MT, and El-Dairi, MA. "Bruch's membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema." Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (December 2017).  Full Text
    • Lee, J, El-Dairi, MA, Tran-Viet, D, Mangalesh, S, Dandridge, A, Jiramongkolchai, K, Viehland, C, and Toth, CA. "LONGITUDINAL CHANGES IN THE OPTIC NERVE HEAD AND RETINA OVER TIME IN VERY YOUNG CHILDREN WITH FAMILIAL EXUDATIVE VITREORETINOPATHY." Retina (Philadelphia, Pa.) (November 22, 2017).  Full Text
    • Jiramongkolchai, K, Bhatti, MT, Fuchs, HE, Cummings, TE, Jiramongkolchai, P, and El-Dairi, MA. "Endodermal Cyst of the Third Nerve in a Child." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 37, no. 3 (September 2017): 311-313.  Full Text
    • Wall, M, Thurtell, MJ, and NORDIC Idiopathic Intracranial Hypertension Study Group, . "Optic disc haemorrhages at baseline as a risk factor for poor outcome in the Idiopathic Intracranial Hypertension Treatment Trial." The British journal of ophthalmology 101, no. 9 (September 2017): 1256-1260.  Full Text
    • Jiramongkolchai, K, Buckley, EG, Bhatti, MT, Muh, CR, Wiggins, RE, Jiramongkolchai, P, and El-Dairi, MA. "Temporary Lumbar Drain as Treatment for Pediatric Fulminant Idiopathic Intracranial Hypertension." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 37, no. 2 (June 2017): 126-132.  Full Text
    • Gospe, SM, Bhatti, MT, and El-Dairi, MA. "Emerging Applications of Optical Coherence Tomography in Pediatric Optic Neuropathies." Seminars in pediatric neurology 24, no. 2 (May 2017): 135-142.  Full Text
    • Bleicher, ID, and El-Dairi, MA. "Swelling Superimposed on Atrophy Masks Optic Nerve Pathology." The Journal of pediatrics 180 (January 2017): 285-285.e1.  Full Text
    • Liu, KC, Rosdahl, JA, and El-Dairi, MA. "A 71-year-old man with bilateral vision loss." Digital journal of ophthalmology : DJO 23, no. 3 (January 2017): 85-87.  Full Text
    • Shashi, V, Pena, LDM, Kim, K, Burton, B, Hempel, M, Schoch, K, Walkiewicz, M, McLaughlin, HM, Cho, M, Stong, N, Hickey, SE, Shuss, CM, Undiagnosed Diseases Network, , Freemark, MS, Bellet, JS, Keels, MA, Bonner, MJ, El-Dairi, M, Butler, M, Kranz, PG, Stumpel, CTRM, Klinkenberg, S, Oberndorff, K, Alawi, M, Santer, R, Petrovski, S, Kuismin, O, Korpi-Heikkilä, S, Pietilainen, O, Aarno, P, Kurki, MI, Hoischen, A, Need, AC, Goldstein, DB, and Kortüm, F. "De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype." American Journal of Human Genetics 100, no. 1 (January 2017): 179-null.  Full Text
    • Aboobakar, IF, Mettu, P, and El-Dairi, MA. "Nonglaucomatous Cupping: Fundus Photography and Spectral Domain Optical Coherence Tomography Imaging Features." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 36, no. 4 (December 2016): 402-403.  Full Text
    • Shashi, V, Pena, LDM, Kim, K, Burton, B, Hempel, M, Schoch, K, Walkiewicz, M, McLaughlin, HM, Cho, M, Stong, N, Hickey, SE, Shuss, CM, Undiagnosed Diseases Network, , Freemark, MS, Bellet, JS, Keels, MA, Bonner, MJ, El-Dairi, M, Butler, M, Kranz, PG, Stumpel, CTRM, Klinkenberg, S, Oberndorff, K, Alawi, M, Santer, R, Petrovski, S, Kuismin, O, Korpi-Heikkilä, S, Pietilainen, O, Aarno, P, Kurki, MI, Hoischen, A, Need, AC, Goldstein, DB, and Kortüm, F. "De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype." American Journal of Human Genetics 99, no. 4 (October 2016): 991-999.  Full Text
    • Mettu, P, Bhatti, MT, El-Dairi, MA, Price, EB, Lin, AY, Alaraj, A, Setabutr, P, and Moss, HE. "Orbito-Masticatory Syndrome." Journal of Neuro Ophthalmology : the Official Journal of the North American Neuro Ophthalmology Society 36, no. 3 (September 2016): 308-312.  Full Text
    • Silverstein, E, Freedman, S, Zéhil, G-P, Jiramongkolchai, K, and El-Dairi, M. "The macula in pediatric glaucoma: quantifying the inner and outer layers via optical coherence tomography automatic segmentation." Journal of American Association for Pediatric Ophthalmology and Strabismus 20, no. 4 (August 2016): 332-336.  Full Text
    • Gospe, SM, Bhatti, MT, and El-Dairi, MA. "Anatomic and visual function outcomes in paediatric idiopathic intracranial hypertension." The British journal of ophthalmology 100, no. 4 (April 2016): 505-509.  Full Text
    • Wen, JC, Freedman, SF, El-Dairi, MA, and Asrani, S. "Microcystic Macular Changes in Primary Open-angle Glaucoma." Journal of glaucoma 25, no. 3 (March 2016): 258-262.  Full Text
    • Duncan, JE, Freedman, SF, and El-Dairi, MA. "The incidence of neovascular membranes and visual field defects from optic nerve head drusen in children." Journal of Aapos : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus 20, no. 1 (February 2016): 44-48.  Full Text
    • Tariq Bhatti, M, Maldonado, RS, Mettu, P, and El-Dairi, M. "Authors respond." Neurology: Clinical Practice 6, no. 1 (February 1, 2016): 9-10. (Letter)  Full Text
    • Jiramongkolchai, K, Freedman, SF, and El-Dairi, MA. "Retinal Changes in Pediatric Glaucoma and Nonglaucomatous Optic Atrophy." American journal of ophthalmology 161 (January 2016): 188-95.e1.  Full Text
    • Rothman, AL, Sevilla, MB, Mangalesh, S, Gustafson, KE, Edwards, L, Cotten, CM, Shimony, JS, Pizoli, CE, El-Dairi, MA, Freedman, SF, and Toth, CA. "Thinner Retinal Nerve Fiber Layer in Very Preterm Versus Term Infants and Relationship to Brain Anatomy and Neurodevelopment." American journal of ophthalmology 160, no. 6 (December 2015): 1296-1308.e2.  Full Text
    • Maldonado, RS, Mettu, P, El-Dairi, M, and Bhatti, MT. "The application of optical coherence tomography in neurologic diseases." Neurology. Clinical practice 5, no. 5 (October 2015): 460-469.  Full Text
    • Petrovski, S, Shashi, V, Petrou, S, Schoch, K, McSweeney, KM, Dhindsa, RS, Krueger, B, Crimian, R, Case, LE, Khalid, R, El-Dairi, MA, Jiang, Y-H, Mikati, MA, and Goldstein, DB. "Exome sequencing results in successful riboflavin treatment of a rapidly progressive neurological condition." Cold Spring Harbor molecular case studies 1, no. 1 (October 2015): a000257-.  Full Text
    • Shashi, V, Petrovski, S, Schoch, K, Crimian, R, Case, LE, Khalid, R, El-Dairi, MA, Jiang, Y-H, Mikati, MA, and Goldstein, DB. "Sustained therapeutic response to riboflavin in a child with a progressive neurological condition, diagnosed by whole-exome sequencing." Cold Spring Harbor molecular case studies 1, no. 1 (October 2015): a000265-.  Full Text
    • El-Dairi, MA, Chang, L, Proia, AD, Cummings, TJ, Stinnett, SS, and Bhatti, MT. "Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 35, no. 3 (September 2015): 246-253.  Full Text
    • Willoughby, AS, Ying, G-S, Toth, CA, Maguire, MG, Burns, RE, Grunwald, JE, Daniel, E, Jaffe, GJ, and Comparison of Age-Related Macular Degeneration Treatments Trials Research Group, . "Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials." Ophthalmology 122, no. 9 (September 2015): 1846-53.e5.  Full Text
    • Willoughby, AS, Ying, G-S, Toth, CA, Maguire, MG, Burns, RE, Grunwald, JE, Daniel, E, Jaffe, GJ, and Comparison of Age-Related Macular Degeneration Treatments Trials Research Group, . "Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials." Ophthalmology 122, no. 9 (September 2015): 1846-53.e5.  Full Text
    • Aboobakar, IF, Mettu, P, and El-Dairi, MA. "Optic Nerve Head Pit With Sectoral Inner Retinal Hypoplasia: A Bottomless Pit." Jama Ophthalmology 133, no. 6 (June 11, 2015): e1572-null.  Full Text
    • Goldhagen, BE, Bhatti, MT, Srinivasan, PP, Chiu, SJ, Farsiu, S, and El-Dairi, MA. "Retinal atrophy in eyes with resolved papilledema detected by optical coherence tomography." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 35, no. 2 (June 2015): 122-126.  Full Text
    • Margeta, MA, Buckley, EG, and El-Dairi, MA. "Low cerebrospinal fluid protein in prepubertal children with idiopathic intracranial hypertension." Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 19, no. 2 (April 2015): 135-139.  Full Text
    • Rothman, AL, Sevilla, MB, Freedman, SF, Tong, AY, Tai, V, Tran-Viet, D, Farsiu, S, Toth, CA, and El-Dairi, MA. "Assessment of retinal nerve fiber layer thickness in healthy, full-term neonates." American journal of ophthalmology 159, no. 4 (April 2015): 803-811.  Full Text
    • Ghasia, FF, El-Dairi, M, Freedman, SF, Rajani, A, and Asrani, S. "Reproducibility of spectral-domain optical coherence tomography measurements in adult and pediatric glaucoma." J Glaucoma 24, no. 1 (January 2015): 55-63.  Full Text  Link to Item
    • Huntington Study Group Reach2HD Investigators, . "Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial." The Lancet. Neurology 14, no. 1 (January 2015): 39-47.  Full Text
    • Huntington Study Group Reach2HD Investigators, . "Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial." The Lancet. Neurology 14, no. 1 (January 2015): 39-47.  Full Text
    • Ely, AL, El-Dairi, MA, and Freedman, SF. "Cupping reversal in pediatric glaucoma--evaluation of the retinal nerve fiber layer and visual field." American journal of ophthalmology 158, no. 5 (November 2014): 905-915.  Full Text
    • Noval, S, Freedman, SF, Asrani, S, and El-Dairi, MA. "Incidence of fovea plana in normal children." Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 18, no. 5 (October 2014): 471-475.  Full Text
    • Tong, AY, El-Dairi, M, Maldonado, RS, Rothman, AL, Yuan, EL, Stinnett, SS, Kupper, L, Cotten, CM, Gustafson, KE, Goldstein, RF, Freedman, SF, and Toth, CA. "Evaluation of optic nerve development in preterm and term infants using handheld spectral-domain optical coherence tomography." Ophthalmology 121, no. 9 (September 2014): 1818-1826.  Full Text
    • Al-Haddad, C, El Chaar, L, Antonios, R, El-Dairi, M, and Noureddin, B. "Interocular Symmetry in Macular Choroidal Thickness in Children." Journal of Ophthalmology 2014 (2014): 1-7.  Full Text
    • Vickers, LA, and El-Dairi, MA. "Subacute vision loss in a young, obese female." J Pediatr 163, no. 5 (November 2013): 1518-1519.  Full Text  Link to Item
    • Allingham, MJ, Cabrera, MT, O'Connell, RV, Maldonado, RS, Tran-Viet, D, Toth, CA, Freedman, SF, and El-Dairi, MA. "Racial variation in optic nerve head parameters quantified in healthy newborns by handheld spectral domain optical coherence tomography." J AAPOS 17, no. 5 (October 2013): 501-506.  Full Text  Link to Item
    • Kuo, AN, McNabb, RP, Chiu, SJ, El-Dairi, MA, Farsiu, S, Toth, CA, and Izatt, JA. "Correction of ocular shape in retinal optical coherence tomography and effect on current clinical measures." Am J Ophthalmol 156, no. 2 (August 2013): 304-311.  Full Text  Link to Item
    • Ghasia, FF, Freedman, SF, Rajani, A, Holgado, S, Asrani, S, and El-Dairi, M. "Optical coherence tomography in paediatric glaucoma: time domain versus spectral domain." Br J Ophthalmol 97, no. 7 (July 2013): 837-842.  Full Text  Link to Item
    • Mukherjee, N, El-Dairi, MA, and Bhatti, MT. "Optic Nerve Sheath Fenestration—Indications and Techniques." US Ophthalmic Review 06, no. 02 (2013): 125-125.  Full Text
    • Moreno, TA, El-Dairi, MA, and Cabrera, MT. "Isolated Horner syndrome and syringomyelia in a child." J AAPOS 16, no. 6 (December 2012): 569-570.  Full Text  Link to Item
    • Prakalapakorn, SG, Freedman, SF, Lokhnygina, Y, Gandhi, NG, Holgado, S, Chen, BB, and El-Dairi, MA. "Longitudinal reproducibility of optical coherence tomography measurements in children." J AAPOS 16, no. 6 (December 2012): 523-528.  Full Text  Link to Item
    • Gandhi, NG, Prakalapakorn, SG, El-Dairi, MA, Jones, SK, and Freedman, SF. "Icare ONE rebound versus Goldmann applanation tonometry in children with known or suspected glaucoma." Am J Ophthalmol 154, no. 5 (November 2012): 843-849.e1.  Full Text  Link to Item
    • El-Dairi, MA, Ghasia, F, and Bhatti, MT. "Pediatric optic neuritis." Int Ophthalmol Clin 52, no. 3 (2012): 29-xii. (Review)  Full Text  Link to Item
    • El-Dairi, M, Holgado, S, Asrani, S, and Freedman, SF. "Optical coherence tomography (OCT) measurements in black and white children with large cup-to-disc ratios." Exp Eye Res 93, no. 3 (September 2011): 299-307.  Full Text  Link to Item
    • Gupta, PK, Asrani, S, Freedman, SF, El-Dairi, M, and Bhatti, MT. "Differentiating glaucomatous from non-glaucomatous optic nerve cupping by optical coherence tomography. (Published online)" Open Neurol J 5 (January 26, 2011): 1-7.  Full Text  Link to Item
    • Chang, L, El-Dairi, MA, Frempong, TA, Burner, EL, Bhatti, MT, Young, TL, and Leigh, F. "Optical coherence tomography in the evaluation of neurofibromatosis type-1 subjects with optic pathway gliomas." J AAPOS 14, no. 6 (December 2010): 511-517.  Full Text  Link to Item
    • El-Dairi, MA, Holgado, S, Asrani, SG, Enyedi, LB, and Freedman, SF. "Correlation between optical coherence tomography and glaucomatous optic nerve head damage in children." Br J Ophthalmol 93, no. 10 (October 2009): 1325-1330.  Full Text  Link to Item
    • El-Dairi, M, Bhatti, MT, and Vaphiades, MS. "A shot of adrenaline." Surv Ophthalmol 54, no. 5 (September 2009): 618-624.  Full Text  Link to Item
    • El-Dairi, MA, Asrani, SG, Enyedi, LB, and Freedman, SF. "Optical coherence tomography in the eyes of normal children." Arch Ophthalmol 127, no. 1 (January 2009): 50-58.  Full Text  Link to Item
    • Mansour, AM, Al Dairy, M, Hamam, R, and Hidayat, AA. "Chronic granulomatous disease presenting as retinal mass. (Published online)" Cases J 1, no. 1 (October 21, 2008): 257-.  Full Text  Link to Item
    • El-Dairi, MA, Holgado, S, O'Donnell, T, Buckley, EG, Asrani, S, and Freedman, SF. "Optical coherence tomography as a tool for monitoring pediatric pseudotumor cerebri." J AAPOS 11, no. 6 (December 2007): 564-570.  Full Text  Link to Item
    • El-Dairi, MA, and Wallace, DK. "Advances in the management of retinopathy of prematurity." Expert Review of Ophthalmology 2, no. 3 (June 2007): 429-442.  Full Text
    • Mansour, AM, El-Dairi, MA, Shehab, MA, Shahin, HK, Shaaban, JA, and Antonios, SR. "Periocular corticosteroids in diabetic papillopathy." Eye (Lond) 19, no. 1 (January 2005): 45-51.  Full Text  Link to Item
    • Mansour, AM, and Al-Dairy, M. "Modifications in cataract surgery for the morbidly obese patient." J Cataract Refract Surg 30, no. 11 (November 2004): 2265-2268.  Full Text  Link to Item
    • Khawam, E, El-Dairi, M, Al-Haddad, C, and Younis, M. "Inferior oblique overaction/contracture following retrobulbar anesthesia for cataract extraction with a positive Bielschowsky Head Tilt test to the contralateral shoulder. A report of one case." Binocul Vis Strabismus Q 19, no. 4 (2004): 247-250.  Link to Item
    • Ma'luf, RN, Zein, WM, El Dairi, MA, and Bashshur, ZF. "Bilateral subperiosteal orbital hematomas and Henoch-Schönlein purpura." Arch Ophthalmol 120, no. 10 (October 2002): 1398-1399.  Link to Item

  • Other Articles

    • Tariq Bhatti, M, El-Dairi, MA, Cummings, TJ, and Proia, AD. ""Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis" Useful, but No Substitute for Thorough Histopathology: Response." Journal of Neuro Ophthalmology : the Official Journal of the North American Neuro Ophthalmology Society 36, no. 3 (September 2016): 343-344. (Letter)  Full Text
    • Bhatti, MT, El-Dairi, MA, Cummings, TJ, and Proia, AD. "Diagnostic Algorithm for Suspected Giant Cell Arteritis: Response." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 36, no. 2 (June 2016): 225-227.  Full Text
    • Jiramongkolchai, K, Bhatti, MT, Proia, A, Freedman, SF, and El-Dairi, MA. "Formation of Macular Inner Nuclear Layer Cysts in Optic Atrophy." Investigative Ophthalmology & Visual Science 57, no. 3 (March 2016): 989-991. (Letter)  Full Text
    • El-Dairi, M. "Optical coherence tomography in the management of congenital glaucoma." The British journal of ophthalmology 98, no. 2 (February 2014): 149-150.  Full Text
    • Chang, L, El-Dairi, MA, Young, TL, and Bhatti, MT. "Retinal nerve fiber layer thickness in children with optic pathway gliomas." Am J Ophthalmol 152, no. 3 (September 2011): 504-505. (Letter)  Full Text  Link to Item
    • Wallace, DK, El-Dairi, M, and Freedman, SF. "Technological advances in pediatric eye care." Arch Ophthalmol 127, no. 6 (June 2009): 805-806.  Full Text  Link to Item
    • Freedman, SF, and El-Dairi, M. "Reply." Journal of AAPOS 12, no. 4 (2008): 422-423.  Full Text
    • III, JLM, Khawam, E, Dairi, ME, and Al-Haddad, C. "RE: Inferior oblique overaction/contracture following retrobulbar anesthesia for cataract extraction with a positive bielschowsky head tilt test to the contralateral shoulder. A report of one case (BV&SQ 2004; 19:247-250) [1] (multiple letters)." Binocular Vision and Strabismus Quarterly 20, no. 1 (2005): 8-9.

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